Patent application number | Description | Published |
20080275171 | Flexible Hydrogel-Based Functional Composite Materials - A composite having a flexible hydrogel polymer formed by mixing an organic phase with an inorganic composition, the organic phase selected from the group consisting of a hydrogel monomer, a crosslinker, a radical initiator, and/or a solvent. A polymerization mixture is formed and polymerized into a desired shape and size. | 11-06-2008 |
20080279908 | Hydroxyapatite-Binding Peptides for Bone Growth and Inhibition - Hydroxyapatite (HA)-binding peptides are selected using combinatorial phage library display. Pseudo-repetitive consensus amino acid sequences possessing periodic hydroxyl side chains in every two or three amino acid sequences are obtained. These sequences resemble the (Gly-Pro-Hyp) | 11-13-2008 |
20100098761 | Polymer Compositions For Biomedical And Material Applications - The invention relates to composite materials that contain a polymer matrix and aggregates, and in some embodiments, methods of making, and methods of using these materials. Preferably, the aggregates are calcium phosphate aggregates. Preferably, the material is resistant to fracture. In further embodiments, the materials are used in surgical procedures of bone replacement. In further embodiments, the materials contain polyhedral silsesquioxanes and/or biodegradable segments. In further embodiments, the polymer matrix comprises biomolecules. | 04-22-2010 |
20100159011 | Compositions For Biomedical Applications - The invention relates to composite materials that contain a polymer matrix and aggregates, and in some embodiments, methods of making, and methods of using these materials. Preferably, the aggregates are calcium phosphate aggregates. Preferably, the material is resistant to fracture. In further embodiments, the materials are used in surgical procedures of bone replacement. In further embodiments, the materials contain polyhedral silsesquioxanes and/or biodegradable segments. In further embodiments, the polymer matrix comprises biomolecules. | 06-24-2010 |
20100280561 | Thermal-Responsive Polymer Networks, Compositions, And Methods And Applications Related Thereto - The invention relates to materials comprising polymer network containing siloxanes or organic-based core structures, preferably the materials have thermal-responsive properties. In some embodiments, the invention relates to an organic core functionalized with polymers. In another embodiment, organic core-polymer conjugates comprise polylactone segments. The organic core-polymer conjugates may be crosslinked together to form a material, and these materials may be functionalized with bioactive compounds so that the materials have desirable biocompatibility or bioactivity when used in medical devices. In some embodiments, the invention relates to silsesquioxane groups functionalized with polymers. In another embodiment, silsequioxane-polymer conjugates comprise polylactone segments. The silsequioxane-polymer conjugates may be crosslinked together to form a material, and these materials may be functionalized with bioactive compounds so that the materials have desirable biocompatibility or bioactivity when used in medical devices. In further embodiments, the invention relates to composite materials that contain a polymer matrix and aggregates, and in some embodiments, methods of making, and methods of using these materials. Preferably, the aggregates are calcium phosphate aggregates. Preferably, the material is resistant to fracture. In further embodiments, the materials are used in surgical procedures of bone replacement. In further embodiments, the materials contain polyhedral silsesquioxanes and/or biodegradable segments | 11-04-2010 |
20120258160 | CHEMICALLY MODIFIED CELLULOSE FIBROUS MESHES FOR USE AS TISSUE ENGINEERING SCAFFOLDS - Cellulose and sulfated cellulose fibrous meshes exhibiting robust structural and mechanical integrity in water were fabricated using a combination of electrospinning, thermal-mechanical annealing and chemical modifications. The sulfated fibrous mesh exhibited higher retention capacity for human recombinant bone morphogenetic protein-2 than the cellulose mesh, and the retained proteins remained biologically active for at least 7 days. The sulfated fibrous mesh also more readily supported the attachment and osteogenic differentiation of rat bone marrow stromal cells in the absence of osteogenic growth factors. These properties combined make the sulfated cellulose fibrous mesh a promising bone tissue engineering scaffold. | 10-11-2012 |
20140058058 | MONOMERS AND POLYMERS FOR FUNCTIONAL POLYCARBONATES AND POLY(ESTER-CARBONATES) AND PEG-CO-POLYCARBONATE HYDROGELS - The invention generally relates to functional polymers and hydrogels. More particularly, the invention provides versatile monomers and polymers with well-defined functionalities, e.g., polycarbonates and poly(ester-carbonates), compositions thereof, and methods for making and using the same. The invention also provides cytocompatible poly(ethylene glycol)-co-polycarobonate hydrogels (e.g., crosslinked by copper-free, strain-promoted “click” chemistry). | 02-27-2014 |
20140088618 | ELASTOMERIC AND DEGRADABLE HIGH-MINERAL CONTENT POLYMER COMPOSITES - The invention provides novel compositions of hydroxyapatite and block co-polymers, methods of their preparation, and uses thereof, wherein the co-polymers have degradable hydrophobic blocks and hydrophilic blocks for stable interfacing with hydroxyapatite, resulting in stable polymer-hydroxyapatite suspensions. The super-hydrophilicity, strengthened mechanical integrity, and retained structural integrity of the HA-PELA composite in aqueous environment represent major advantages over the HA-PLA composites for skeletal tissue engineering applications. | 03-27-2014 |
20140255333 | THERMAL RESPONSIVE POLYMER SILOXANES, COMPOSITIONS, AND METHOD AND APPLICATIONS RELATED THERETO - The invention relates to materials comprising siloxanes, preferably the materials have thermal-responsive properties. In some embodiments, the invention relates to silsesquioxane groups functionalized with polymers. In another embodiment, silsequioxane-polymer conjugates comprise polylactone segments. The silsequioxane-polymer conjugates may be crosslinked together to form a material, and these materials may be functionalized with bioactive compounds so that the materials have desirable biocompatibility or bioactivity when used in medical devices. In further embodiments, the invention relates to composite materials that contain a polymer matrix and aggregates, and in some embodiments, methods of making, and methods of using these materials. Preferably, the aggregates are calcium phosphate aggregates. Preferably, the material is resistant to fracture. In further embodiments, the materials are used in surgical procedures of bone replacement. In further embodiments, the materials contain polyhedral silsesquioxanes and/or biodegradable segments. | 09-11-2014 |
20140357806 | THERMAL-RESPONSIVE POLYMER NETWORKS, COMPOSITIONS, AND METHODS AND APPLICATIONS RELATED THERETO - The invention relates to materials comprising polymer network containing siloxanes or organic-based core structures, preferably the materials have thermal-responsive properties. In some embodiments, the invention relates to an organic core functionalized with polymers. In another embodiment, organic core-polymer conjugates comprise polylactone segments. The organic core-polymer conjugates may be crosslinked together to form a material, and these materials may be functionalized with bioactive compounds so that the materials have desirable biocompatibility or bioactivity when used in medical devices. | 12-04-2014 |
20150209477 | COMPOSITIONS FOR BIOMEDICAL APPLICATIONS - The invention relates to composite materials that contain a polymer matrix and aggregates, and in some embodiments, methods of making, and methods of using these materials. Preferably, the aggregates are calcium phosphate aggregates. Preferably, the material is resistant to fracture. In further embodiments, the materials are used in surgical procedures of bone replacement. In further embodiments, the materials contain polyhedral silsesquioxanes and/or biodegradable segments. In further embodiments, the polymer matrix comprises biomolecules. | 07-30-2015 |
20150320913 | MULTI-FUNCTIONAL SURFACE COATING OF IMPLANTS - The invention provides novel surface coatings having surface polymer brushes with zwitterionic and antibiotics-conjugated side chains and synergistic anti-fouling and bactericidal properties. The surface coatings may be prepared using highly efficient surface-initiated “living” polymerization. The design of the surface polymer brushes are highly modular, allowing independent tuning of the anti-fouling and bactericidal properties, e.g., by varying the chemical nature of the zwitterionic motif and the antibiotic agent, the chemistry through which the antibiotic agent is conjugated to the polymer side chains, the molecular weight of the polymer brushes (e.g., thickness of coating and density of respective functional motifs), and the spatial arrangement of the respective functional motifs (e.g., homopolymers, block copolymers, random copolymers) to achieve optimal and sustained anti-infection outcome for a given application. | 11-12-2015 |
20150335790 | COMPOSITIONS AND METHODS FOR TEMPLATING THREE-DIMENSIONAL MINERALIZATION - The invention provides novel compositions and methods for three-dimensional mineralization templated by synthetic scaffolds having zwitterionic mediators. The invention enables 3-D mineralization nucleation and growth of minerals in a well-controlled and defined manner. The composite materials prepared by the disclosed methods are cytocompatible and/or biodegradable and are suitable for use as medical implants in a variety of applications in skeletal tissue repair and regeneration. For example, cytocompatible zwitterionic sulfobetaine ligands are employed to facilitate 3-D mineralization of HA across covalently crosslinked hydrogels. The overall charge-neutral zwitterionic hydrogel effectively recruited oppositely charged precursor ions while overcame excessive swelling exhibited by anionic and cationic hydrogels under physiological conditions, resulting in denser and structurally well-integrated mineralized composite materials. | 11-26-2015 |
Patent application number | Description | Published |
20080267326 | Multi-channel receiver with improved AGC - An improved multi-channel receiver for satellite broadcast applications or the like. In an exemplary embodiment, an AGC loop, under the control of an AGC processor, controls the gain of an analog sub-receiver adapted to simultaneously receive multiple signals to achieve a desired AGC setpoint signal intensity from the sub-receiver. Multiple digital demodulators, coupled to the sub-receiver by an analog-to-digital converter (ADC), demodulate the multiple received signals. The AGC controller, based upon which of the received signals are being demodulated, selects the desired AGC setpoint from a table of setpoints. The AGC controller may also provide selective power control to circuitry in the receiver and select the resolution of the ADC. The controller updates the AGC loop with step values selected from a group of values by an AGC control algorithm. Different groups of step values may be used by the controller depending on whether the signals are fading or not. | 10-30-2008 |
20080268798 | Multi-channel receiver with improved AGC - An improved multi-channel receiver for satellite broadcast applications or the like. In an exemplary embodiment, an AGC loop, under the control of an AGC processor, controls the gain of an analog sub-receiver adapted to simultaneously receive multiple signals to achieve a desired AGC setpoint signal intensity from the sub-receiver. Multiple digital demodulators, coupled to the sub-receiver by an analog-to-digital converter (ADC), demodulate the multiple received signals. The AGC controller, based upon which of the received signals are being demodulated, selects the desired AGC setpoint from a table of setpoints. The AGC controller may also provide selective power control to circuitry in the receiver and select the resolution of the ADC. The controller updates the AGC loop with step values selected from a group of values by an AGC control algorithm. Different groups of step values may be used by the controller depending on whether the signals are fading or not. | 10-30-2008 |
20110188489 | MULTI-CHANNEL RECEIVER WITH IMPROVED AGC - An improved multi-channel receiver for satellite broadcast applications or the like. In an exemplary embodiment, a primary AGC loop controls an analog sub-receiver adapted to simultaneously receive multiple signals. Multiple digital demodulators, coupled to the sub-receiver, demodulate the multiple received signals. Multiple secondary AGC loops, one for each received signal, compensate for variations in demodulated signal strengths caused by the primary AGC loop. A feed-forward AGC compensation technique generates scalar control values for scaling the demodulated signals before the demodulated signals are processed by the secondary AGC loops. This at least partially compensates for gain variations caused by the primary AGC, reducing received signal drop-outs before the secondary AGC loops can compensate for the gain variations. Because of systemic delays in the sub-receiver and the demodulators, the scalar control values are independently timed to be coincident with the variations in the demodulated signal strengths caused by the primary AGC loop. | 08-04-2011 |
Patent application number | Description | Published |
20150077119 | THREE-DIMENSIONAL FOCUSING INDUCED POLARIZATION EQUIPMENT FOR ADVANCED GEOLOGICAL PREDICTION OF WATER INRUSH DISASTER SOURCE IN UNDERGROUND ENGINEERING - The invention discloses three-dimensional focusing induced polarization equipment for advance geological prediction of a water inrush disaster source in underground engineering, comprising a constant-current multiplex transmitter, an intelligent multichannel receiver, an automatic multi-electrode switch, an industrial personal computer, an observation electrode array and shielding electrodes, wherein electrodes in the observation electrode array are respectively used as a source electrode and observation electrodes; the industrial personal computer controls the constant-current multiplex transmitter to transmit currents of the same polarity to the shielding electrodes and the source electrode, so that the currents of the source electrodes are nearly directed straight ahead of a driving face under the action of the shielding electrodes; the observation electrodes are used for scanning data acquisition, and the data are fed back to the industrial personal computer through the intelligent multi-channel receiver; and the industrial personal computer controls the automatic multi-electrode switch to change the source electrode. | 03-19-2015 |
20150233242 | COMPREHENSIVE ADVANCED GEOLOGICAL DETECTION SYSTEM CARRIED ON TUNNEL BORING MACHINE - The present invention presents a comprehensive advanced geological detection system carried on a tunnel boring machine. The comprehensive advanced geological detection system includes a multifunctional combination main frame, an induced polarization detection device, a seismic wave detection device, an integrated junction device, a borehole ground penetrating radar detection device and a comprehensive interpretation and decision system; the multifunctional combination main frame includes a time division multiplexing control module, an excitation source control module and a parallel data acquisition module; the excitation source control module outputs trigger signals to the three detection devices respectively, and the three detection devices respectively output measurement data and feedback signals to the time division multiplexing control module through the parallel data acquisition module; and the comprehensive interpretation and decision system supports geological interpretations and decisions through the inversion/migration imaging joint inversion of three detection methods. | 08-20-2015 |
20150338549 | TUNNEL CONSTRUCTION LARGE-SCALE INTEGRATED GEOPHYSICAL ADVANCED DETECTION MODEL TEST DEVICE - The present invention discloses a tunnel construction large-scale integrated geophysical advanced detection model test device. The model test device includes a tunnel surrounding rock, a main tunnel model, a model test case, a water-containing geological structure device, a numerical control automated construction device and a main control chamber. The model test device is a large-scale integrated geophysical advanced detection model test device meeting the detection using a seismic wave method, an electromagnetic method and a direct-current electric method. By using the geophysical advanced detection model test device, the geophysical response features of the water-containing geological structure device in front of a tunnel face may be studied, multiple geophysical advanced detection forward and inversion methods for the water-containing geological structure device are verified, and the relationship between some geophysical detection method results and water burst quantity is studied, so as to lay a test foundation for the advanced prediction and water burst quantity prediction of the water-containing geological construction device in actual engineering. | 11-26-2015 |
Patent application number | Description | Published |
20150266745 | Metal Cyanometallate Synthesis Method - A method is provided for synthesizing metal cyanometallate (MCM). The method provides a solution of A | 09-24-2015 |
20150266746 | Metal Cyanometallate Synthesis Method - A method is provided for synthesizing metal cyanometallate (MCM). The method provides a solution of A | 09-24-2015 |
20150357630 | Prussian Blue Analogue Electrodes without Zeolitic Water Content - A battery is provided with a hexacyanometallate cathode. The battery cathode is made from hexacyanometallate particles overlying a current collector. The hexacyanometallate particles have the chemical formula A | 12-10-2015 |
20150357646 | Sodium and Potassium Ion Batteries with Halogen Salts - A sodium or potassium battery is provided, prior to an initial charge and discharge cycle, with a halogen salt additive. As is conventional, the battery is made up of the following components: an anode, a cathode, and an electrolyte. In addition, the battery includes a halogen salt (MX), where M is a metal and X is a halogen element. The halogen salt is added to the anode, the cathode, the electrolyte, or combinations thereof. The concentration MX with respect to the component(s) to which it is added is in the range of 0.01% to 10% in weight. The element X can be selected from the group of halogen elements listed in the Periodic Table. M is a material such as lithium, sodium, potassium, cesium, magnesium, calcium, barium, titanium, manganese, iron, cobalt, nickel, copper, zinc, ammonium, or combinations thereof. Advantageously, the electrolyte may be either aqueous or non-aqueous. | 12-10-2015 |
20160056467 | Alkali-Ion Battery with Enhanced Transition Metal Cyanometallate Electrode Structure - An alkali-ion battery is provided with a transition metal cyanometallate (TMCM) sheet cathode and a non-alkaline metal anode. The fabrication method mixes TMCM powders, conductive additives, and a polytetrafluoroethylene binder with a solution containing water, forming a wet paste. The wet paste is formed into a free-standing sheet of cathode active material, which is laminated to a cathode current collector, forming a cathode electrode. The free-standing sheet of cathode active material has a thickness typically in the range of 100 microns to 2 millimeters. The cathode electrode is assembled with a non-alkaline metal anode electrode and an ion-permeable membrane interposed between the cathode electrode and anode electrode, forming an assembly. The assembly is dried at a temperature of greater than 100 degrees C. The dried assembly is then inserted into a container (case) and electrolyte is added. Thick anodes made from free-standing sheets of active material can be similarly formed. | 02-25-2016 |