Jerrold M.
Jerrold M. Deisenroth, Concord, MA US
Patent application number | Description | Published |
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20120124668 | Method for Immunizing Data in Computer Systems from Corruption - A system for immunizing a computer network against adverse effects caused by the receipt of a corrupting message. Each message transfers into a protocol-based controlled environment for a specific recipient where message criteria determine whether the incoming message is deemed to be a valid or suspicious message. Transmission criteria determine the final message disposition. If the message is valid, it is delivered to a recipient computer system in the network. If the incoming message is suspicious, the message is isolated in the controlled environment where the transmission criteria may provide remote access to the recipient. | 05-17-2012 |
Jerrold M. Olefsky, San Diego, CA US
Patent application number | Description | Published |
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20100239589 | Methods and Compositions for Ameliorating Diabetes and Symptoms Thereof - The present invention relates generally to the Tlr4 signaling pathway specifically in the hematopoietic system and its contribution to insulin resistance of liver and adipose tissue. The hematopoietic component expressing Tlr4 is a principle propagator of immune signaling and results in insulin resistance. Furthermore, disclosed herein are methods and compositions for treating or preventing disorders associated with insulin resistance using a Tlr4 antagonist. | 09-23-2010 |
Jerrold M. Olefsky, Solana Beach, CA US
Patent application number | Description | Published |
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20120295975 | METHODS OF TREATING INFLAMMATORY CONDITIONS - The present invention provides methods of treating a β-arrestin2 mediated and/or GPR120 mediated response in a subject. The β-arrestin2 mediated and/or GPR120 mediated response can be inflammation, including diabetes, inflammation associated with obesity and obesity. The methods can comprise administering to a subject a therapeutically effective amount of a compound predicted to bind a β-arrestin2 molecule and/or GPR120, wherein the compound selectively activates a β-arrestin2-dependent signaling pathway of GPR120. | 11-22-2012 |
20140357556 | Novel Target for Diagnosis and Treatment of Diabetes and Cardiovascular Diseases - Diagnostic, prognostic, and treatment methods, compositions, and kits for enhancing insulin secretion and beta cell numbers and functions, and controlling glycemia associated with diabetes, obesity, atherosclerosis, stroke, myocardial infarction, and other cardiovascular diseases, by modulating FKN/CX3CR1 expression levels or activities, and its downstream signaling pathways in a subject in need or at risk. | 12-04-2014 |