| Patent application number | Description | Published |
|---|
| 20090286800 | Glucokinase Activators - Compounds are provided for use with glucokinase that comprise the formula: | 11-19-2009 |
| 20100093767 | Mitotic Kinase Inhibitors - The invention relates to inhibitors of enzymes that disrupt the assembly and function of the mitotic spindle, compositions comprising the inhibitors of Formula (I), kits and articles of manufacture comprising the inhibitors and inhibitor compositions, and methods of using the inhibitors and inhibitor compositions. The inhibitors and inhibitor compositions are useful for treating, preventing or modulating diseases in which mitotic kinesins, including kinesin-like spindle protein (KSP), may be involved; symptoms of such diseases; or the effect of other physiological events mediated by mitotic kinesins, including KSP. | 04-15-2010 |
| 20100190763 | Poly (ADP-Ribose) Polymerase (PARP) Inhibitors - Disclosed are compounds of the following formula: | 07-29-2010 |
| 20110158989 | Poly (ADP-Ribose) Polymerase (PARP) INHIBITORS - Disclosed are compounds of the following formula: | 06-30-2011 |
| 20120094992 | POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS - Compounds of the following formula are provided for use in inhibiting Poly (ADP-ribose) Polymerase (PARP): | 04-19-2012 |
| 20120122835 | Poly (ADP-Ribose) Polymerase (PARP) Inhibitors - Disclosed are compounds of the following formula: | 05-17-2012 |
| 20120225887 | Glucokinase Activators - Compounds are provided for use with glucokinase that comprise the formula: | 09-06-2012 |
| 20130274239 | POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS - Disclosed are compounds of the following formula: | 10-17-2013 |
| 20140045859 | Glucokinase Activators - Compounds are provided for use with glucokinase that comprise the formula: | 02-13-2014 |
| 20150031652 | POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS - Disclosed are compounds of the following formula: | 01-29-2015 |
| Patent application number | Description | Published |
|---|
| 20110296515 | METHOD FOR MANAGING COMPUTER RESOURCES ACCESSED BY A PROGRAM OPERATING IN A RESTRICTED ENVIRONMENT - A resource manager of an operating system of a data processing system receives a first request from a first program for a ticket for accessing at least one of resources of the data processing system. In response to the first request, the resource manager determines whether the first program is entitled to access the resource. The ticket for accessing the resource is issued to the first program if the first program is entitled to access the resource. The ticket can be used by a second program to obtain rights to access the resource by acquiring the ticket from the first program, where the second program would not otherwise be entitled to access the resource based on a security profile associated with the second program. | 12-01-2011 |
| 20120185863 | METHODS FOR RESTRICTING RESOURCES USED BY A PROGRAM BASED ON ENTITLEMENTS - In response to a request for launching a program, a list of one or more application frameworks to be accessed by the program during execution of the program is determined. Zero or more entitlements representing one or more resources entitled by the program during the execution are determined. A set of one or more rules based on the entitlements of the program is obtained from at least one of the application frameworks. The set of one or more rules specifies one or more constraints of resources associated with the at least one application framework. A security profile is dynamically compiled for the program based on the set of one or more rules associated with the at least one application framework. The compiled security profile is used to restrict the program from accessing at least one resource of the at least one application frameworks during the execution of the program. | 07-19-2012 |
| 20130283344 | METHODS FOR RESTRICTING RESOURCES USED BY A PROGRAM BASED ON ENTITLEMENTS - In response to a request for launching a program, a list of one or more application frameworks to be accessed by the program during execution of the program is determined. Zero or more entitlements representing one or more resources entitled by the program during the execution are determined. A set of one or more rules based on the entitlements of the program is obtained from at least one of the application frameworks. The set of one or more rules specifies one or more constraints of resources associated with the at least one application framework. A security profile is dynamically compiled for the program based on the set of one or more rules associated with the at least one application framework. The compiled security profile is used to restrict the program from accessing at least one resource of the at least one application frameworks during the execution of the program. | 10-24-2013 |
| 20150347774 | RESTRICTED RESOURCE CLASSES OF AN OPERATING SYSTEM - Techniques for access control of a data processing system are described. In one embodiment, in response to a request from an application for accessing a resource of a data processing system, it is determined a first class of resources the requested resource belongs. A second class of resources the application is entitled to access is determined based on a resource entitlement encoded within the application and authorized by a predetermined authority. The application is allowed to access the resource if the first class and the second class of resources are matched. The application is denied from accessing the resource if the first class and the second class are not matched, regardless an operating privilege level of the application. | 12-03-2015 |
| Patent application number | Description | Published |
|---|
| 20090088076 | FLASH PAIRING BETWEEN BLUETOOTH DEVICES - In an example embodiment, a technique that allows a device unable to display a confirmation value and/or unable to receive a keyed data entry to confirm a generated confirmation value with a confirmation value produced by a second device. The confirmation value is output one character at a time. For example, for performing a six digit numerical comparison (NC), each digit is presented one at a time enabling a user to compare the output digit with the corresponding digit output by the second device. | 04-02-2009 |
| 20100061380 | Load Balancing across Multiple Network Address Translation (NAT) Instances and/or Processors - Disclosed are, inter alia, methods, apparatus, computer-storage media, mechanisms, and means associated with load balancing across multiple network address translation (NAT) instances and/or processors. N network address translation (NAT) processors and/or instances are each assigned a portion of the source address traffic in order to load balance the network address translation among them. Additionally, the address space of translated addresses is partitioned and uniquely assigned to the NAT processors and/or instances such that the identification of the assigned NAT processor and/or instance associated with a received translated address can be readily determined there from, and then used to network address translate that received packet. | 03-11-2010 |
| 20130145044 | Discovering Security Devices Located on a Call Path and Extending Bindings at those Discovered Security Devices - In one embodiment, an endpoint elicits a pattern of STUN responses to identify security devices located on a call path. The endpoint then uses address information from the identified security devices to establish an efficient media flow with a remote endpoint. The endpoint can optimize the number of network devices and network paths that process the endpoint's keepalive message. Additionally, the endpoint may request custom inactivity timeouts with each of the identified security devices for reducing bandwidth consumed by keepalive traffic. | 06-06-2013 |
| Patent application number | Description | Published |
|---|
| 20130227437 | VIRTUAL AREA COMMUNICATIONS - A virtual area has a spatial visualization and includes zones that are associated with respective geometric boundaries located in relation to the spatial visualization. Realtime data stream connections between sources and sinks of network nodes in the zones of the virtual area are administered to provide a wide variety of virtual area applications, including virtual area applications that implement spatial rules for one or more synchronous conferencing services (e.g., instant messaging, such as text chat, audio conferencing, video conferencing, application sharing, and file sharing). | 08-29-2013 |
| 20140115059 | BRIDGING PHYSICAL AND VIRTUAL SPACES - Examples of systems and methods for bridging virtual and physical spaces are described. In some of these examples, a particular communicant's real world state drives changes in one or more of the communications connections, virtual state, and communications interface of the particular communicant or another communicant. | 04-24-2014 |
| 20140115502 | BRIDGING PHYSICAL AND VIRTUAL SPACES - Examples of systems and methods for bridging virtual and physical spaces are described. In some of these examples, a particular communicant's real world state drives changes in one or more of the communications connections, virtual state, and communications interface of the particular communicant or another communicant. | 04-24-2014 |
| Patent application number | Description | Published |
|---|
| 20090069226 | Transmucosal delivery of peptides and proteins - Provided are methods and compositions for enhancing the transmucosal absorption of bioactive peptides and proteins. More particularly, the invention provides compositions for enhancing the transmucosal absorption of bioactive peptides and proteins, such as exendin-4, PYY, PYY3-36, and GLP-1 and their analogs and derivatives, wherein the compositions comprise an absorption enhancing mixture of a cationic polyamino acid, at least one additional absorption enhancing agent, and a buffer that is compatible with the polyamino acid. Also provided are methods for enhancing the transmucosal absorption and bioavailability of bioactive peptides and proteins using such compositions. | 03-12-2009 |
| 20090291886 | TRANSMUCOSAL DELIVERY OF PEPTIDES AND PROTEINS - Provided are methods and compositions for enhancing the transmucosal absorption of bioactive peptides and proteins. More particularly, the invention provides compositions for enhancing the transmucosal absorption of bioactive peptides and proteins, such as exendin-4, PYY, PYY | 11-26-2009 |
| 20140093552 | Multilayer Biodegradable Microparticles for Sustained Release of Therapeutic Agents - Microparticles are prepared by a method that includes: (a) forming a layer comprising a first polymer on a solid surface by depositing a first composition one or more times on the solid surface, wherein the first composition comprises the first polymer and a first solvent, and evaporating the first solvent in the first composition; (b) forming one or more layers comprising a second polymer and a therapeutic agent by depositing a second composition on all or part of the layer formed in step (a), wherein the second composition comprises the second polymer, the therapeutic agent, and a second solvent; and evaporating the second solvent in the second composition; and (c) forming an additional layer comprising a third polymer by depositing a third composition one or more times on a previously formed layer, wherein the third composition comprises the third polymer and a third solvent; and evaporating the third solvent in the third composition. | 04-03-2014 |
| 20150157725 | TRANSMUCOSAL DELIVERY OF PEPTIDES AND PROTEINS - Provided are methods and compositions for enhancing the transmucosal absorption of bioactive peptides and proteins. More particularly, the invention provides compositions for enhancing the transmucosal absorption of bioactive peptides and proteins, such as exendin-4, PYY, PYY3-36, and GLP-1 and their analogs and derivatives, wherein the compositions comprise an absorption enhancing mixture of a cationic polyamino acid, at least one additional absorption enhancing agent, and a buffer that is compatible with the polyamino acid. Also provided are methods for enhancing the transmucosal absorption and bioavailability of bioactive peptides and proteins using such compositions. | 06-11-2015 |
| Patent application number | Description | Published |
|---|
| 20080200383 | Pharmaceutical Formulations Comprising Incretin Peptide and Aprotic Polar Solvent - The present disclosure is directed to stable pharmaceutical formulations and uses thereof. | 08-21-2008 |
| 20110212138 | SUSTAINED RELEASE FORMULATIONS USING NON-AQUEOUS CARRIERS - The disclosure provides one-component, injectable, sustained release formulations which comprise microspheres containing active pharmaceutical ingredients (e.g., exenatide), wherein the microspheres are suspended in a non-aqueous carrier. The non-aqueous carrier can be an oil, a fractionated oil, triglycerides, diglycerides, monoglycerides, propylene glycol fatty acid diesters, and the like. The formulations offer distinct advantages of long shelf life for the stability and potency of the formulation and sustained release of active pharmaceutical ingredients to reduce the frequency of medication dosing and to increase patient compliance. | 09-01-2011 |
| 20150056285 | SUSTAINED RELEASE FORMULATIONS USING NON-AQUEOUS CARRIERS - The disclosure provides one-component, injectable, sustained release formulations which comprise microspheres containing active pharmaceutical ingredients (e.g., exenatide), wherein the microspheres are suspended in a non-aqueous carrier. The non-aqueous carrier can be an oil, a fractionated oil, triglycerides, diglycerides, monoglycerides, propylene glycol fatty acid diesters, and the like. The formulations offer distinct advantages of long shelf life for the stability and potency of the formulation and sustained release of active pharmaceutical ingredients to reduce the frequency of medication dosing and to increase patient compliance. | 02-26-2015 |
| 20150111824 | Pharmaceutical Formulations Comprising Incretin Mimetic Peptide and Aprotic Polar Solvent - The present disclosure is directed to stable pharmaceutical formulations and uses thereof. | 04-23-2015 |
| Patent application number | Description | Published |
|---|
| 20140251786 | System for Harvesting Oriented Light for Carbon Dioxide Reduction - A system and method for harvesting oriented light for reducing carbon dioxide to produce fuels, such as methane, are disclosed. The present disclosure also relates to oriented photocatalytic semiconductor surfaces that may include oriented photocatalytic capped colloidal nanocrystals (PCCN) which may form oriented photoactive materials. The disclosed photocatalytic system for harvesting oriented light may include a polarization system that employs reflective or polarizing surfaces, such as mirror surfaces for collecting solar energy, and orient the light rays for maximum absorption and energy conversion on oriented photoactive material. The photocatalytic system may also include elements necessary to collect and transfer methane, for subsequent transformation into electrical energy. | 09-11-2014 |
| 20140252275 | System for Harvesting Oriented Light - Water Splitting - A system and method for splitting water to produce hydrogen and oxygen employing focused polarized sunlight energy is disclosed. Hydrogen and oxygen may then be stored for later use as fuels. The system and method use inorganic capping agents that cap the surface of semiconductor nanocrystals to form photocatalytic capped colloidal nanocrystals, which may be deposited and oriented on a substrate to form an oriented photoactive material. The oriented photoactive material may be employed in the system to harvest sunlight and produce energy necessary for water splitting. The system may also include a light polarization system and elements necessary to collect, transfer, and store hydrogen and oxygen, for subsequent transformation into electrical energy. | 09-11-2014 |
| 20140256532 | Oriented Photocatalytic Semiconductor Surfaces - The present disclosure relates to oriented photocatalytic semiconductor surfaces which may include photocatalytic capped colloidal nanocrystals (PCCNs) positioned all in the same orientation. The photoactive material may be employed in a plurality of photocatalytic energy conversion applications such as the photocatalytic reduction of carbon dioxide and water splitting, among others. The disclosed oriented PCCNs, within the oriented photoactive material, may also exhibit different shapes and sizes, and higher efficiency in a light harvesting process. Having all the PCCNs oriented at the same angle and dipole moment may allow the light to interact with the dipole at an increased efficiency, to predict the polarity of the light or a more efficient interaction with the nanocrystals substrate, and therefore, increasing the harvesting efficiency by controlling different parts of the light spectrum in the same system. | 09-11-2014 |
| 20140262742 | Substrate for Increased Efficiency of Semiconductor Photocatalysts - A high surface area grid having two mesh sheets aligned in opposite direction to each other is disclosed. One mesh sheet may be horizontally aligned while the other may be vertically aligned. Piezoelectric actuators may be attached along the sides of each wire sheet, employing piezoelectric actuators to allow a precise control of the displacement of the wires. High surface area grid may be employed in the formation of a photoactive material, where semiconductor photocatalysts may be deposited onto high surface area grid. Photoactive material may be employed for a plurality of photocatalytic energy conversion applications such as water splitting and carbon dioxide reduction. Employing a high surface area grid with the capability of dynamically-controlled dimensions may increase efficiency of semiconductor photocatalysts on its surface. | 09-18-2014 |
| 20140262743 | System for Harvesting Oriented Light for Water Splitting and Carbon Dioxide Reduction - A photosynthetic system for splitting water to produce hydrogen and using the produced hydrogen for the reduction of carbon dioxide into methane is disclosed. The disclosed photosynthetic system employs photoactive materials that include oriented photocatalytic capped colloidal nanocrystals (PCCN) within their composition, in order to harvest sunlight and obtain the energy necessary for water splitting and subsequent carbon dioxide reduction processes. The photosynthetic system may also include elements necessary to transfer water produced in the carbon dioxide reduction process, for subsequent use in water splitting process. The systems may also include elements necessary to store oxygen and collect and transfer methane for subsequent transformation of methane into energy. | 09-18-2014 |
| 20140262806 | Method for Increasing Efficiency of Semiconductor Photocatalysts - A method and composition for producing a photoactive material including photocatalytic capped colloidal nanocrystals (PCCN) and plasmonic nanoparticles are disclosed. The PCCN may include a semiconductor nanocrystal synthesis and an exchange of organic capping agents with inorganic capping agents. Additionally, the PCCN may be deposited between the plasmonic nanoparticles, and may act as photocatalysts for redox reactions. The photoactive material may be used in a plurality of photocatalytic energy conversion applications, such as water splitting and CO | 09-18-2014 |
| 20140272623 | SYSTEM FOR INCREASING EFFICIENCY OF SEMICONDUCTOR PHOTOCATALYSTS EMPLOYING A HIGH SURFACE AREA SUBSTRATE - A system for energy production may include a photoactive material with photocatalytic capped colloidal nanocrystals (PCCN) and plasmonic nanoparticles over a high surface area gridded substrate for increasing light harvesting efficiency. The formation of PCCN may include a semiconductor nanocrystal synthesis and an exchange of organic capping agents with inorganic capping agents. Additionally, the PCCN may be deposited between the plasmonic nanoparticles, and may act as photocatalysts for redox reactions. The photoactive material may be used in a plurality of photocatalytic energy conversion applications such as water splitting or CO | 09-18-2014 |
| 20140301904 | System for Harvesting Oriented Light - Water Splitting - A system and method for splitting water to produce hydrogen and oxygen employing focused polarized sunlight energy is disclosed. Hydrogen and oxygen may then be stored for later use as fuels. The system and method use inorganic capping agents that cap the surface of semiconductor nanocrystals to form photocatalytic capped colloidal nanocrystals, which may be deposited and oriented on a substrate to form an oriented photoactive material. The oriented photoactive material may be employed in the system to harvest sunlight and produce energy necessary for water splitting. The system may also include a light polarization system and elements necessary to collect, transfer, and store hydrogen and oxygen, for subsequent transformation into electrical energy. | 10-09-2014 |
| 20140301905 | System for Harvesting Oriented Light - Water Splitting - A system and method for splitting water to produce hydrogen and oxygen employing focused polarized sunlight energy is disclosed. Hydrogen and oxygen may then be stored for later use as fuels. The system and method use inorganic capping agents that cap the surface of semiconductor nanocrystals to form photocatalytic capped colloidal nanocrystals, which may be deposited and oriented on a substrate to form an oriented photoactive material. The oriented photoactive material may be employed in the system to harvest sunlight and produce energy necessary for water splitting. The system may also include a light polarization system and elements necessary to collect, transfer, and store hydrogen and oxygen, for subsequent transformation into electrical energy. | 10-09-2014 |
| 20140339072 | Photocatalytic CO2 Reduction System - A system employing sunlight energy for reducing CO | 11-20-2014 |
| 20140342254 | Photo-catalytic Systems for Production of Hydrogen - A system for splitting water and producing hydrogen for later use as an energy source may include the use of a photoactive material including PCCN and plasmonic nanoparticles. A method for producing the PCCN may include a semiconductor nanocrystal synthesis and an exchange of organic capping agents with inorganic capping agents. The PCCN may be deposited between the plasmonic nanoparticles and may act as photocatalysts for redox reactions. The photoactive material may be used in presence of water and sunlight to split water into hydrogen and oxygen. Production of charge carriers may be triggered by photo-excitation and enhanced by the rapid electron resonance from localized surface plasmon resonance of plasmonic nanoparticles. By combining different semiconductor materials for PCCN and plasmonic nanoparticles and by changing their shapes and sizes, band gaps may be tuned to expand the range of wavelengths of sunlight usable by the photoactive material. The system may include elements for collecting, transferring, and storing hydrogen and oxygen, for subsequent transformation into electrical energy. | 11-20-2014 |
| 20140349281 | System and Method for Dispensing Barcoded Solutions - The present disclosure provides a system capable of dispensing DNA encoding solutions at controllable flow rates and in uniform patterns, allowing sufficient DNA to be deposited onto a substrate for subsequent detection and identification of the substrate. The disclosed dispensing system may also include a feedback mechanism capable of validating that sufficient DNA has been applied to a substrate so that a barcode may be generated, detected, and identified at a later time. | 11-27-2014 |
| 20140349303 | System and Method for Producing and Reading DNA Barcodes - The present disclosure relates to biological material identification systems and methods. DNA oligomers may be used to encode for specific characteristics of biological materials. Encoding may be done by depositing suitable amounts of DNA oligomers onto a portion of a biological material. To identify the biological materials, the encoded portions of the biological materials may be extracted and immersed in buffer solutions. Then, lateral flow tests may be used to decode the DNA for interpretation, creating a readable barcode that may be compared with a database to determine if the biological material may be approved. | 11-27-2014 |
| 20140349861 | Method for Distinguishing Biological Material Products - A method for encoding and identifying biological materials is disclosed. The method may include encoding and identifying plants from which controlled substances may be derived and other materials for which movement and distribution may need to be tracked. The biological material may be first encoded using DNA oligomers. A spray method or the use of an encoded substrate, both using these DNA oligomers for encoding the biological material, may be employed. The biological material, or a part of the biological material, may be first encoded by atomizing a solution containing DNA oligomers onto it and then dried by an appropriate method. Thereafter, the part of the encoded biological material, or the nitrocellulose substrate, may be dissolved with a buffer solution for extracting the DNA oligomers. Then, the dissolved solution may be used for generating a barcode by a suitable detection scheme. | 11-27-2014 |
