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| 20120081880 | SOLID STATE LIGHT SOURCE LIGHT BULB - A light emitting apparatus includes a lamp base, a light-transmissive bulb envelope, a light source for emitting light, and a heat sink coupled to the light source. A solid state LED light bulb may further include a down conversion material. The down conversion material is disposed within the bulb envelope, remote from the light source and between the light source and the lamp base. The heat sink may include at least one metal fin and, additionally or alternatively, include a mesh disposed over at least an outer portion of the bulb envelope. A solid state light bulb may include a light guide for directing the light emitted by the light source. The solid state light bulb configurations place the light source and heat sink at the apex of the light bulb envelope, distant from the lamp base, in order to dissipate heat produced by the light source into the environment. In addition, at least part of the heat sink is outside the light bulb envelope to maximize the heat dissipation. | 04-05-2012 |
| 20130100659 | SCATTERED-PHOTON EXTRACTION-BASED LIGHT FIXTURES - A scattered photon extraction light fixture includes an optic element having a first surface; a light source for emitting short wavelength radiation, the light source disposed opposite, perpendicular, or tangential to the first surface of the optic element; a wavelength-conversion material, disposed on the first surface of the optic element, for receiving and down converting at least some of the short wavelength radiation emitted by the light source and transferring a portion of the received and down converted radiation; and one or more reflectors positioned opposite the wavelength-conversion material. A scattered photon extraction light system includes a plurality of light emitting fixtures. One or more wavelength-conversion materials, in the embodiments of the present invention, are disposed remotely from the light source(s), and used to absorb radiation in one spectral region and emit radiation in another spectral region. Lighting efficiency is improved by capturing the short wavelength and down-converted radiation. | 04-25-2013 |
| 20140168941 | SCATTERED-PHOTON EXTRACTION-BASED LIGHT FIXTURES - A scattered photon extraction light fixture includes an optic element having a first surface; a light source for emitting short wavelength radiation, the light source disposed opposite, perpendicular, or tangential to the first surface of the optic element; a wavelength-conversion material, disposed on the first surface of the optic element, for receiving and down converting at least some of the short wavelength radiation emitted by the light source and transferring a portion of the received and down converted radiation; and one or more reflectors positioned opposite the wavelength-conversion material. A scattered photon extraction light system includes a plurality of light emitting fixtures. One or more wavelength-conversion materials, in the embodiments of the present invention, are disposed remotely from the light source(s), and used to absorb radiation in one spectral region and emit radiation in another spectral region. Lighting efficiency is improved by capturing the short wavelength and down-converted radiation. | 06-19-2014 |
| 20150308638 | SCATTERED-PHOTON EXTRACTION-BASED FIXTURES - A light fixture includes a light source, a wavelength-conversion material, and a reflector. The light source is configured to emit a first radiation, and has a front surface and a back surface. The wavelength-conversion material is arranged under the front surface and configured to convert the first radiation to a second radiation which has a first portion not able to reach the reflector and a second portion able to reach the reflector. The reflector is arranged over the back surface and configured to reflect the second portion away from the light source without passing through the wavelength-conversion material. The reflector has an end distant from the light source and is arranged in an elevation different from that of the wavelength-conversion material. | 10-29-2015 |
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| 20090041852 | DRY POWDER COMPOSITIONS AND SYSTEMS FOR POULTRY VACCINATION - This invention provides a dry powder composition for poultry vaccination via inhalation comprising an effective amount of a poultry vaccine agent, and a supporting amount of carriers for said poultry vaccine agent, said carriers comprising a combination of a reducing or non-reducing sugar and a biocompatible polymer, said dry powder composition being in the form of particles having an average particle size from 2 to 30 μm and a particle size polydispersity from 1.1 to 4.0. This invention also relates to a method for producing said dry powder compositions and a system for vaccination of poultry by inhalation. | 02-12-2009 |
| 20090239900 | QUININE AND QUINIDINE SALTS, METHODS FOR MAKING THEM, AND PHARMACEUTICAL FORMULATIONS COMPRISING THEM - The present invention provides a combination of:
| 09-24-2009 |
| 20090326078 | PROCESS FOR PREPARING A SOLID DOSAGE FORM - This invention provides a process for preparing a solid dosage form, comprising:—preparing an aqueous slurry, solution or suspension of (a) a powder material, and (b) a mixture of one or more polyols and one or more maltodextrins, and—spray drying the resultant aqueous slurry, solution or suspension, thereby obtaining particles which are directly compressible into a solid dosage form being able to disintegrate in an aqueous medium within no more than 15 minutes. | 12-31-2009 |
| 20100105784 | Pharmaceutical Pellets Comprising Modified Starch and Therapeutic Applications Therefor - Vaginal use compositions comprising pellets prepared from a debranched starch. Pellets may be conveniently prepared via extrusion/spheronization. | 04-29-2010 |
| 20110008454 | IMMEDIATE RELEASE PHARMACEUTICAL GRANULE COMPOSITIONS AND A CONTINUOUS PROCESS FOR MAKING THEM - A pharmaceutical or veterinary granule composition in the form of a mixture consisting essentially of: (i) at least one drug classifiable as Class II or Class IV of the Biopharmaceutical Classification System, wherein said drug (i) constitutes from 0.5% to 20% by weight of the composition, and excipients, said pharmaceutical or veterinary granule composition providing a drug release of at least 70% within 10 minutes in water, (ii) a first excipient being a maltodextrin representing from 40% by weight to 80% by weight of said composition, (iii) a wetting amount of a second excipient being a polyethylene glycol having a weight number molecular weight between 300 and 5,000, said second excipient comprising a solid fraction and a liquid fraction, and representing from 15% to 40% by weight of said composition, and optionally one or more pharmaceutically acceptable fillers selected from the group consisting of hydrocolloids, glidants, lubricants, surfactants and diluents, wherein the weight ratio of said first excipient (ii) to said second excipient (iii) is in a range from 1:1 to 5:1. | 01-13-2011 |
| 20110027377 | IMMEDIATE RELEASE PHARMACEUTICAL GRANULE COMPOSITIONS AND A CONTINUOUS PROCESS FOR MAKING THEM - A pharmaceutical or veterinary granule composition in the form of a mixture consisting essentially of: (i) at least one drug classifiable as Class II or Class IV of the Biopharmaceutical Classification System, wherein said drug (i) constitutes from above about 20% to 50% by weight of the composition, said pharmaceutical or veterinary granule composition providing a drug release of at least 70% within 10 minutes in water, (ii) a first excipient being a maltodextrin representing from 40% by weight to 85% by weight of said composition, (iii) a wetting amount of a second excipient being a polyethylene glycol having a weight number molecular weight between 300 and 5,000, said second excipient comprising a solid fraction and a liquid fraction, and representing from 15% to 40% by weight of said composition, and optionally one or more pharma-ceutically acceptable fillers selected from the group consisting of hydrocolloids, glidants, lubricants, surfactants and diluents, wherein the weight ratio of said first excipient (ii) to said second excipient (iii) is in a range from 1:1 to 5:1. | 02-03-2011 |
| 20110108646 | PROCESS AND APPARATUS FOR CONTINUOUS WET GRANULATION OF POWDER MATERIAL - An apparatus for wet granulating a powder material comprises:—a barrel having a granulation chamber and being provided with a first inlet ( | 05-12-2011 |
| 20110150940 | DRY POWDER COMPOSITIONS AND SYSTEMS FOR POULTRY VACCINATION - This invention provides a dry powder composition for poultry vaccination via inhalation comprising an effective amount of a poultry vaccine agent, and a supporting amount of carriers for said poultry vaccine agent, said carriers comprising a combination of a reducing or non-reducing sugar and a biocompatible polymer, said dry powder composition being in the form of particles having an average particle size from 2 to 30 μm and a particle size polydispersity from 1.1 to 4.0. This invention also relates to a method for producing said dry powder compositions and a system for vaccination of poultry by inhalation. | 06-23-2011 |
| 20110294864 | AQUEOUS COACERVATE COMPOSITIONS SUITABLE FOR MAKING POWDERS AND WATER-SOLUBLE FORMULATIONS OF BIOLOGICALLY-ACTIVE AGENTS - Aqueous gel-free two-phase coacervate compositions including a coacervate phase and an equilibrium water phase, comprising a mixture of:
| 12-01-2011 |
| 20120207823 | PHARMACEUTICAL PELLETS COMPRISING MODIFIED STARCH AND THERAPEUTIC APPLICATIONS THEREFOR - Vaginal use compositions comprising pellets prepared from a debranched starch. Pellets may be conveniently prepared via extrusion/spheronization. | 08-16-2012 |
| 20130149357 | Porous Degradable Polyelectrolyte Microspheres as Vaccine Vector - The present invention discloses a composition comprising a polyelectrolyte complex and a polyol, characterised in that said polyol is in amorphous form. Optionally, the composition further comprises one or more drugs, wherein each drug has a molecular weight of at least 1000 Dalton. Said compositions are obtainable by spray-drying. The compositions may be prepared in particle form and as a suspension of particles. Pharmaceutical compositions are also provided for use in extracellular drug delivery. Pharmaceutical compositions are also provided that exhibit a controlled dual drug release. | 06-13-2013 |
| 20140154293 | INTRAVAGINAL DELIVERY SYSTEM - The present invention in general relates to an intravaginal delivery system as well as uses thereof and methods for manufacturing and use of the same. In particular the present invention relates to an intravaginal delivery system for the controlled release of one or more organic acids, such as lactic acid; said intravaginal delivery system being characterized in that it comprises a combination of ethylene vinyl acetate (EVA) copolymers and carboxylic polymers, such as for example methacrylic acid-methacrylic ester copolymers. | 06-05-2014 |
| 20140178471 | MULTI-LAYERED RELEASE FORMULATION - The present invention in general relates to a pharmaceutical dosage form comprising a multi-layered release formulation formed by co-extrusion. Said formulation in particular comprises a core layer comprising at least one polymer selected from polycaprolactone, ethylcellulose, or combinations thereof; and a coat layer comprising at least one (co)polymer selected from the list comprising: polyethylene oxide; polyethylene glycol; Basic Butylated Methacrylate (co)polymer; a (co)polymer of polyvinylcaprolactam, PEG and polyvinylacetate; or combinations thereof. | 06-26-2014 |
| 20140255498 | PHARMACEUTICAL NANOSUSPENSION - The present invention in general relates to a pharmaceutical suspension comprising nano-sized cocrystals of at least one active ingredient and at least one dicarboxylic acid. It in particular relates to a pharmaceutical suspension comprising nano-sized cocrystals of at least one anthelmintic drug and at least one dicarboxylic acid. The invention further relates to uses, methods for use and methods for manufacturing the pharmaceutical suspension according to this invention. | 09-11-2014 |
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| 20110110486 | APPARATUS AND METHODS FOR COMPUTED TOMOGRAPHY IMAGING - Apparatus and methods for computed tomography (CT) imaging are provided. One method includes providing a patient table to move along an examination axis of a rotating gantry of a CT imaging system having at least one imaging detector. The imaging detector includes a pixelated detector array. The method further includes configuring the CT imaging system to perform an overlapping helical CT scan by controlling a speed of the moving patient table along the examination axis through a field of view (FOV) of the at least one imaging detector of the rotating gantry. | 05-12-2011 |
| 20110147599 | SYSTEMS AND METHODS FOR FILTERING NOISE IN PIXELATED IMAGE DETECTORS - Systems and methods for filtering noise in pixelated photon counting image detectors are provided. One method includes obtaining image information including event count information for a pixelated solid-state photon counting radiation detector and obtaining a count-rate threshold. The method further includes filtering the event count information based on the count-rate threshold. | 06-23-2011 |
| 20110155899 | METHOD AND APPARATUS FOR ACQUIRING RADIATION DATA - Method and apparatus for extending a count rate capability of a detector array. The method includes receiving photons at a detector array, counting the photons that are above a first energy threshold using a first counter, counting the photons that are above a different second energy threshold using a second counter, and calculating a pile-up estimate using the photon counts from the first and second counters. | 06-30-2011 |
| 20110155918 | SYSTEMS AND METHODS FOR PROVIDING A SHARED CHARGE IN PIXELATED IMAGE DETECTORS - Systems and methods for providing a shared charge in pixelated image detectors are provided. One method includes providing a plurality of pixels for a pixelated solid state photon detector in a configuration such that a charge distribution is detected by at least two pixels and obtaining charge information from the at least two pixels. The method further includes determining a position of an interaction of the charge distribution with the plurality of pixels based on the obtained charge information. | 06-30-2011 |
| 20110220783 | METHODS AND SYSTEMS FOR CALIBRATING A NUCLEAR MEDICINE IMAGING SYSTEM - Methods and systems for calibrating a nuclear medicine imaging are provided. One method includes acquiring spatially determined non-uniform radiation flux information from a calibration scan of a calibration source using a gamma camera having an attached non-parallel-hole collimator. The method further includes determining a measured non-uniform count density profile from the acquired non-uniform radiation flux information. The method also includes creating a gamma camera uniformity correction map derived from (i) the measured non-uniform count density profile and (ii) a modeled or calculated non-uniform count density profile for calibrating the NM imaging system. | 09-15-2011 |
| 20130193337 | SYSTEMS AND METHODS FOR PROVIDING A SHARED CHARGE IN PIXELATED IMAGE DETECTORS - Systems and methods for providing a shared charge in pixelated image detectors are provided. One method includes providing a plurality of pixels for a pixelated solid state photon detector in a configuration such that a charge distribution is detected by at least two pixels and obtaining charge information from the at least two pixels. The method further includes determining a position of an interaction of the charge distribution with the plurality of pixels based on the obtained charge information. | 08-01-2013 |
| 20150065873 | METHODS AND SYSTEMS FOR CONTROLLING MOVEMENT OF DETECTORS HAVING MULTIPLE DETECTOR HEADS - Methods and systems for controlling movement of detectors having multiple detector heads are provided. One system includes a gantry, a patient support structure supporting a patient table thereon, and a plurality of detector units. At least some of the detector units are rotatable to position the detector units at different angles relative to the patient table. The imaging system further includes a detector position controller configured to control the position of the rotatable detector units, wherein at least some of the rotatable detector units positioned adjacent to each other have an angle of rotation to allow movement of the rotatable detector units a distance greater than a gap between adjacent rotatable detector units The detector position controller is configured to calculate at least one of field of view avoidance information or collision avoidance information to determine an amount of movement for one or more of the rotatable detector units. | 03-05-2015 |
| 20150177392 | IMAGING SYSTEM USING HIGH AND LOW ENERGY COLLIMATION - A customizable and upgradable imaging system is provided. Imaging detector columns are installed in a gantry to receive imaging information about a subject. Imaging detector columns can extend and retract radially as well as be rotated orbitally around the gantry. The system can provide detector columns that include both high and low energy collimation. The detector columns may also use side shielding and adaptively disable detector elements based on emission information and shielding information. This system can be a Nuclear Medicine (NM) imaging system to acquire Single Photon Emission Computed Tomography (SPECT) image information. | 06-25-2015 |
| 20150177393 | IMAGING SYSTEM USING INDEPENDENTLY CONTROLLABLE DETECTORS - A customizable and upgradable imaging system is provided. Imaging detector columns are installed in a gantry to receive imaging information about a subject. Imaging detector columns can extend and retract radially as well as be rotated orbitally around the gantry. The gantry can be partially populated with detector columns and the detector columns can be partially populated with detector elements. The system can automatically adjust an imaging operation based on installation information related to partial population or other factors such as scan type or subject specific information. This system can be a Nuclear Medicine (NM) imaging system to acquire Single Photon Emission Computed Tomography (SPECT) image information. | 06-25-2015 |
| 20150276949 | IMAGING SYSTEM AND METHOD OVERCOMING OBSTRUCTIONS USING INDEPENDENTLY CONTROLLABLE DETECTORS - Imaging systems, methods, and computer readable mediums are provided. Image detectors are installed in a gantry to detect image information related to a subject. If obstructions are detected related to the field of view of an image detector, a system matrix can be updated accordingly. Thus, upon image reconstruction, artifacts related to obstructions can be minimized or altogether eliminated. This system can be a Nuclear Medicine (NM) imaging system to acquire Single Photon Emission Computed Tomography (SPECT) image information. | 10-01-2015 |
| 20150342543 | COMPACT GANTRY SYSTEM USING INDEPENDENTLY CONTROLLABLE DETECTORS - A gantry system is provided. The gantry system may be used for acquiring image data and reconstructing the image data into output images. Image detectors include a detector arm and detector head. Image detectors are attached to a gantry in a compact configuration such that the image detector head may extend into the bore of a stator. The system can be a Nuclear Medicine (NM) imaging system to acquire Single Photon Emission Computed Tomography (SPECT) image information. | 12-03-2015 |
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| 20110112036 | PHARMACEUTICAL COMPOSITIONS OF PACLITAXEL, PACLITAXEL ANALOGS OR PACLITAXEL CONJUGATES AND RELATED METHODS OF PREPARATION AND USE - Pharmaceutical compositions useful for hydrophobic agents paclitaxel, paclitaxel analogs and conjugates thereof (e g ANG1005) which do not contain Cremophor™ The compositions further comprise an optional tonicity agent, a buffering agent a bulking agent and a solubilizmg agent which is not Cremophor™ Methods of preparing said compositions and of said compositions in the treatment of cancer are also included. | 05-12-2011 |
| 20110288009 | LEPTIN AND LEPTIN ANALOG CONJUGATES AND USES THEREOF - The present invention features a compound having the formula A-X-B, where A is peptide vector capable of enhancing transport of the compound across the blood-brain barrier or into particular cell types, X is a linker, and B is a leptin, a leptin analog, or OB receptor agonist. The compounds of the invention can be used to treat any disease in which increased amounts of leptin are desired, such as metabolic diseases including obesity and diabetes. | 11-24-2011 |
| 20110288011 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF - The present invention features a compound having the formula A-X-B, where A is peptide vector capable of enhancing transport of the compound across the blood-brain barrier or into particular cell types, X is a linker, and B is a peptide therapeutic. The compounds of the invention can be used to treat any disease for which the peptide therapeutic is useful. | 11-24-2011 |
| 20120015876 | CONJUGATES OF GLP-1 AGONISTS AND USES THEREOF - The present invention features a compound having the formula A-X-B, where A is peptide vector capable of enhancing transport of the compound across the blood-brain barrier or into particular cell types, X is a linker, and B is a GLP-1 agonist (e.g., exendin-4 or an exendin-4 analog). The compounds of the invention can be used to treat any disease where increased GLP-1 activity is desired, for example, metabolic diseases, such as obesity and diabetes. | 01-19-2012 |
| 20120122798 | TREATMENT OF OVARIAN CANCER USING AN ANTICANCER AGENT CONJUGATED TO AN ANGIOPEP-2 ANALOG - Ovarian cancer is treated with conjugates of an anticancer agent and an Angiopep-2 polypeptide analog (i.e. a polypeptide comprising an ammo acid sequence at least 80% identical to Seq. ID NO:97). Such treatment includes utility in treating metastatic ovarian cancer and in treating patients who have previously exhibited resistance to standard chemotherapeutic agents. Preferred anticancer agents include taxanes while the preferred conjugate is ANG1005, a conjugate comprising three molecules of paclitaxel conjugated to the peptide Angiopep-2. | 05-17-2012 |
| 20120196803 | FUSION PROTEINS FOR DELIVERY OF GDNF AND BDNF TO THE CENTRAL NERVOUS SYSTEM - The present invention relates to a compound that includes a peptide vector, such as angiopep-2 which acts as a carrier across the blood-brain barrier, linked to glial-derived neurotrophic factor (GDNF), brain-derived neurotrophic factor (BDNF), or a related molecule, such as an analog or a fragment thereof. The compounds of the invention may be used to treat any disease where increased neuronal survival or growth is desired, e.g., neurodegenerative diseases, such as Parkinson's disease or amyotrophic lateral sclerosis. Other diseases can be treated using the compounds include schizophrenia and depression. | 08-02-2012 |
| 20120277158 | COMPOSITIONS AND METHODS FOR THE TRANSPORT OF THERAPEUTIC AGENTS - The present invention is directed to conjugates that include a polypeptide capable of crossing the blood-brain barrier or entering one or more cell types attached to a transport vector, i.e., a composition capable of transporting an agent (e.g., a therapeutic agent). In certain cases, the polypeptides are directly conjugated to a lipid or polymeric vector to allow targeted application of a therapeutic agent to treat, for example, a cancer, a neurodegenerative disease, or a lysosomal storage disorder. | 11-01-2012 |
| 20130280281 | SHORT AND D-AMINO ACID-CONTAINING POLYPEPTIDES FOR THERAPEUTIC CONJUGATES AND USES THEREOF - The present invention relates to short polypeptides (e.g., fewer than 19 amino acids in length) and longer polypeptides (e.g., 19 or more amino acids in length) having one or more D-amino acids as targeting moieties. These polypeptides, when conjugated to agents (e.g., therapeutic agents or transport vectors) are capable of transporting the agents across the BBB or into particular cell types. In particular, the short polypeptides can include one or more D-amino acids. These compounds are therefore particularly useful in the treatment of neurological diseases or diseases associated with particular cell types, organs, or tissues. | 10-24-2013 |
| 20140335163 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS - The present invention is related to a compound that includes a lysosomal enzyme and a targeting moiety, for example, where compound is a fusion protein including iduronate-2-sulfatase and Angiopep-2. In certain embodiments, these compounds, owning to the presence of the targeting moiety can crossing the blood-brain barrier or accumulate in the lysosome more effectively than the enzyme alone. The invention also features methods for treating lysosomal storage disorders (e.g., mucopolysaccharidosis Type II) using such compounds. | 11-13-2014 |
| 20150037311 | TARGETED LYSOSOMAL ENZYME COMPOUNDS - The present invention is related to a compound that includes a lysosomal enzyme and a targeting moiety, for example, where compound is a fusion protein including iduronate-2-sulfatase and Angiopep-2. In certain embodiments, these compounds, owning to the presence of the targeting moiety can crossing the blood-brain barrier or accumulate in the lysosome more effectively than the enzyme alone. The invention also features methods for treating lysosomal storage disorders (e.g., mucopolysaccharidosis Type II) using such compounds. | 02-05-2015 |
| 20150147310 | TARGETED ENZYME COMPOUNDS AND USES THEREOF - The present invention is related to a compound that includes (a) α-L-iduronidase (IDUA), fragment, or analog thereof and (b) a targeting moiety, for example, where compound is a fusion protein including IDUA and Angiopep-2. In certain embodiments, these compounds, owning to the presence of the targeting moiety can crossing the blood-brain barrier or accumulate in the lysosome more effectively than the enzyme alone. The invention also features methods for treating mucopolysaccharidosis type I (MPS-I) using such compounds. | 05-28-2015 |
| 20150290341 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS - The present invention is related to a compound that includes a lysosomal enzyme and a targeting moiety, for example, a compound that includes iduronate-2-sulfatase conjugated to Angiopep-2 through a linker formed by specific click chemistry reactions. In certain embodiments, these compounds, owing to the presence of the targeting moiety, can cross the blood-brain barrier or accumulate in the lysosome more effectively than the enzyme alone. The invention also features pharmaceutical compositions containing such compounds and methods for treating lysosomal storage disorders (e.g., mucopolysaccharidosis Type II) using such compounds. | 10-15-2015 |
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| 20090004835 | Method for producing semi-conducting material wafers by moulding and directional crystallization - Wafers of semi-conducting material are formed by moulding and directional crystallization from a liquid mass of this material. A seed, situated at the bottom of the crucible, presents an orientation along non-dense crystallographic planes. The mould is filled with the molten semi-conducting material by means of a piston or by creation of a pressure difference in the device. The mould is preferably coated with a non-wettable anti-adhesive deposit. | 01-01-2009 |
| 20110212630 | METHOD FOR PREPARING A SELF-SUPPORTING CRYSTALLIZED SILICON THIN FILM - The invention relates to a method for preparing a self-supporting crystallized silicon thin film having a grain size of more than 1 mm. The invention also relates to the use of said method for preparing self-supporting silicon bands and to the bands thus obtained. | 09-01-2011 |
| 20110229711 | METHOD OF ASSEMBLING CARBON PARTS BY REFRACTORY BRAZING - The present invention relates to a method of assembling carbon parts using a braze based on silicon carbide. The invention also relates to the parts assembled using such a method. | 09-22-2011 |
| 20110268958 | PROCESS FOR FORMING A NON-STICK COATING BASED ON SILICON CARBIDE - The present invention relates to a process for forming a nonstick coating, said coating being formed from grains of silicon carbide, which are surface-coated with a layer of silicon oxide. It also targets the materials having a coating formed by this process. | 11-03-2011 |
| 20120040139 | MATERIAL HAVING A MULTILAYER ARCHITECTURE AND INTENDED FOR BEING CONTACTED WITH LIQUID SILICON - The present invention relates to novel materials intended for being contacted with liquid silicon and having a multilayer architecture, the intermediate layer of which is formed by a silicon carbide matrix containing at least one carbon nodule. The invention also relates to the method for preparing said materials. | 02-16-2012 |
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| 20090283875 | Self-supported film and silicon wafer obtained by sintering - Self-supported film and silicon wafer obtained by sintering. A silicon wafer for a photovoltaic cell is produced by a debinding step of a self-supported film formed of at least one main thin layer comprising at least 50% volume of silicon particles, devoid of silicon oxide and encapsulated in a polymer matrix protecting them against oxidation, followed by a sintering step to form the silicon wafer. | 11-19-2009 |
| 20110220193 | PHOTOVOLTAIC CELL WITH DISTRIBUTED EMITTER IN A SUBSTRATE, AND METHOD FOR MANUFACTURE OF SUCH A CELL - A photovoltaic cell including a substrate composed of a semiconductor of a first type of conductivity including two main faces substantially parallel with one another, the substrate including a plurality of blind holes, openings of which are positioned in a single one of the two main faces, and the blind holes filled by a semiconductor of a second type of conductivity opposed to the first type of conductivity forming an emitter of the photovoltaic cell. The substrate forms a base of the photovoltaic cell. First collector pins composed of a semiconductor of the second type of conductivity are in contact with the emitter of the photovoltaic cell, and second collector pins composed of a semiconductor of the first type of conductivity are in contact with the substrate and interdigitated with the first collector pins. | 09-15-2011 |
| 20110259316 | MELTING-SOLIDIFICATION FURNACE WITH VARIABLE HEAT EXCHANGE VIA THE SIDE WALLS - The melting and solidification furnace for crystalline material includes a crucible having a bottom and side walls, and means for heating the crystalline material by magnetic induction. The furnace includes at least one lateral thermal insulation system arranged at the periphery of the crucible around the side walls. At least one lateral element of the lateral thermal insulation system moves with respect to the side walls between an insulating position and a position fostering thermal leakage. The lateral thermal insulation system has an electric conductivity of less than 1 S/m and a thermal conductivity of less than 15 W/m/K. | 10-27-2011 |
| 20130001808 | ENCAPSULATION DEVICE HAVING IMPROVED SEALING - An encapsulation device including two casings made of a flexible polymer material, each delimiting a sealed space, and at least one hydrophobic material filling each of the casings, the casings being stacked and sealingly interconnected at peripheral edges thereof, a sealed space then being defined between the two casings for receiving a device to be encapsulated. | 01-03-2013 |
| 20130040105 | DEVICE AND METHOD FOR MECHANICALLY TEXTURING A SILICON WAFER INTENDED TO COMPRISE A PHOTOVOLTAIC CELL, AND RESULTING SILICON WAFER - A solution for texturing silicon wafers configured to constitute photovoltaic (PV) cells. Silicon wafers can be produced, the surface of which include uniformly engraved patterns having a depth of between 5 and 50 μm. | 02-14-2013 |
| 20130098437 | Photovoltaic Cell Having a Structured Back Surface and Associated Manufacturing Method - The invention relates to a photovoltaic cell ( | 04-25-2013 |
| 20130260507 | Method for Forming a Fibrous Layer - The present invention relates to a method for forming, on the surface of one of the sides of a silicon substrate, a fibrous layer having a mean lattice pitch of no more than 2 μm, without requiring soaking. | 10-03-2013 |
| 20140154402 | PRODUCTION OF POLYCRYSTALLINE SILICON BY NATURAL SINTERING FOR PHOTOVOLTAIC APPLICATIONS - Silicon sintering method, without applying an external force, comprising placement of a silicon sample in a furnace, then heat treatment of this sample at, at least one temperature and at least one partial pressure of oxidising species to control the thickness of a silicon oxide layer on its surface. | 06-05-2014 |
| 20140190398 | SYSTEM FOR MANUFACTURING A CRYSTALLINE MATERIAL BY DIRECTIONAL CRYSTALLIZATION PROVIDED WITH AN ADDITIONAL LATERAL HEAT SOURCE - The crystallization system includes a crucible provided with a bottom and with side walls designed to contain the material to be solidified and a device for creating a main thermal gradient inside the crucible in a perpendicular direction to the bottom of the crucible. An additional inductive heating device is arranged at the level of the side walls of the crucible facing the liquid material and without overlapping with the solid phase. This additional inductive heating device is configured to heat a part of the crystalline material located in the vicinity of the triple contact line between the liquid material, the solidified material and the crucible so that the interface between the liquid material and the solidified material forms a convex meniscus in the vicinity of the triple contact line. | 07-10-2014 |
| 20140234602 | MULTILAYER STRUCTURE OFFERING IMPROVED IMPERMEABILITY TO GASES - A multilayer structure including a substrate and a first stack of a layer of SiO | 08-21-2014 |
| 20140261156 | Method of Forming a Crystallized Silicon Layer on the Surface of a Plurality of Substrates - The present invention concerns a method of forming, by liquid phase epitaxial growth, on the surface of a plurality of substrates, a layer of crystallised silicon having a grain size greater than or equal to 200 μm, comprising at least the steps consisting of: (i) arranging a liquid bath formed from a liquid metal solvent phase in which liquid silicon is homogeneously dispersed; (ii) immersing, in the bath of step (i), said substrates ( | 09-18-2014 |
| 20150079772 | Method for Preparing a Coarse-Grain Crystallized Silicon Layer - The present invention relates to a method for forming a crystallised silicon layer made up of grains having an average size of no less than 20 μm, including at least the steps that comprise: (1) providing a layer of silicon to be (re)crystallised, the average grain size of which is less than 10 μm; (2) placing said layer of silicon to be (re)crystallised in contact with a liquid composition at least partially made up of a metal solvent; and (3) exposing the assembly to a thermal treatment suitable for (re)crystallising said layer of silicon with the expected grain size, characterised in that said thermal treatment includes heating the assembly made up of the layer of silicon in contact with said liquid composition to a temperature that is lower than 1410° C. and at least equal to the eutectic temperature in the solvent-silicon phase diagram. | 03-19-2015 |
| 20150155168 | METHOD FOR FORMING AN EPITACTIC SILICON LAYER - The present invention relates to a method for manufacturing an epitactic silicon layer made up of crystallites with a size no lower than 20 μm, including: providing a layer of crystallised silicon the surface of which, being inhomogeneous in terms of the size of the crystallites, is made up of large crystallites with a size no lower than 20 μm, and small crystallites of a smaller size; forming, on the surface of the inhomogeneous silicon layer, a layer of at least one non-nucleating material for the silicon, the thickness of which is adjusted such to cover the entire outer surface of the small crystallites, while leaving all or part of the outer surface of the large crystallites accessible; and carrying out epitaxial growth of a silicon layer on the surface of the assembly obtained at the end of step, under conditions that are suitable for forming the expected epitactic layer. | 06-04-2015 |
| 20150236190 | Device and method for restoring silicon-based photovoltaic solar cells - A restoration device of at least one silicon-based photovoltaic solar cell is provided with a support of the cell and a charge carriers generator configured to generate charge carriers in the photovoltaic solar cell. The device is further provided with a tank designed to be filled by a liquid, and the support is configured to place the photovoltaic solar cell in the liquid. | 08-20-2015 |
| 20150249173 | METHOD FOR MANUFACTURING A MONOLITHIC SILICON WAFER COMPRISING MULTIPLE VERTICAL JUNCTIONS - The present invention relates to a method for manufacturing a monolithic silicon wafer ( | 09-03-2015 |
| 20150263216 | DEVICE AND METHOD FOR RESTORING SILICON-BASED SOLAR CELLS USING AN ULTRASOUND TRANSDUCER - The restoration device of least one silicon-based photovoltaic solar cell includes a support of the cell, a heat source configured to heat the photovoltaic solar cell, and unit for generating charge carriers in the cell. To better accelerate the restoration kinetics of the solar cell, the device includes an ultrasonic transducer designed to generate ultrasonic waves propagating in the photovoltaic solar cell. | 09-17-2015 |
| 20150299897 | METHOD FOR FORMING AN EPITAXIAL SILICON LAYER - The invention relates to a method for forming a crystallised silicon layer having a crystallite size higher than or equal to 100 μm, by the epitaxial growth in a vapour phase, on the surface of at least one silicon substrate, including at least the steps: (i) providing a silicon substrate having a particle size higher than or equal to 100 μm and including a metal impurities content of between 0 ppb and 1 ppm by weight; and (ii) forming the silicon layer on the surface of the substrate heated to a temperature of between 1000 and 1300° C., by decomposition of at least one silicon precursor by unit of an inductive plasma torch, the surface of the substrate for supporting the silicon layer being positioned close to the outlet of the plasma torch in step (ii). | 10-22-2015 |
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| 20110144009 | Brown Adipocyte Progenitors in Human Skeletal Muscle - Brown adipose tissue (“BAT”) progenitor cells and methods for identifying BAT progenitor cells in a population of cells are provided. Methods are also provided for inducing differentiation of BAT progenitor cells into differentiated brown adipocytes, inducing expression or increased activity levels of BAT uncoupling protein-1 (“UCP1”), and for identifying agents capable of inducing differentiation of BAT progenitor cells into brown adipocytes and/or inducing expression or increased activity levels of UCP1. Differentiated brown adipocytes and agents and methods for inducing differentiation of BAT progenitor cells can be used for treatment of or the making of medicaments for the treatment of metabolic diseases or conditions in a patient such as obesity, overweight, impaired glucose tolerance, insulin-resistance, type 2 diabetes, dyslipidemia, hypertension, cardiovascular diseases, metabolic syndrome, and the like. Differentiated brown adipocytes and agents and methods for inducing differentiation of BAT progenitor cells can be used for prevention of hypothermia. | 06-16-2011 |
| 20130303573 | Brown Adipocyte Progenitors in Human Skeletal Muscle - Brown adipose tissue (“BAT”) progenitor cells and methods for identifying BAT progenitor cells in a population of cells are provided. Methods are also provided for inducing differentiation of BAT progenitor cells into differentiated brown adipocytes, inducing expression or increased activity levels of BAT uncoupling protein-1 (“UCP1”), and for identifying agents capable of inducing differentiation of BAT progenitor cells into brown adipocytes and/or inducing expression or increased activity levels of UCP1. Differentiated brown adipocytes and agents and methods for inducing differentiation of BAT progenitor cells can be used for treatment of or the making of medicaments for the treatment of metabolic diseases or conditions in a patient such as obesity, overweight, impaired glucose tolerance, insulin-resistance, type 2 diabetes, dyslipidemia, hypertension, cardiovascular diseases, metabolic syndrome, and the like. Differentiated brown adipocytes and agents and methods for inducing differentiation of BAT progenitor cells can be used for prevention of hypothermia. | 11-14-2013 |
| 20150240206 | Brown Adipocyte Progenitors in Human Skeletal Muscle - This invention relates to brown adipose tissue (BAT) progenitor cells and methods for isolating BAT progenitor cells from skeletal muscle. BAT progenitor cell surface markers and medium and agents for inducing cell differentiation into brown adipocytes are also provided. In some embodiments, the BAT progenitor cell expresses a first cell surface marker associated with endothelial cells, the first cell surface marker being detectable in an antibody based assay using a first antibody. In addition, the BAT progenitor cell can be substantially free of a second cell surface marker associated with endothelial cells, the second cell surface marker being substantially undetectable in said antibody based assay using a second antibody. The BAT progenitor cell can also be substantially free of additional cell surface markers. | 08-27-2015 |
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| 20090175871 | METHOD FOR DEMONSTRATING PRESENCE OR ABSENCE OF MARKERS ASSOCIATED WITH THE PRESENCE AND/OR THE CHEMOSENSITIVITY OF TUMORS - A method for detecting presence or absence of a tumor in a mammal and/or its sensitivity to chemotherapies, including, on a biological sample from said mammal, detecting and/or quantifying: presence of an eEF1A1 protein, and/or presence of antibodies directed against an eEF1A1 protein or a fragment including at least one epitope of eEF1a1 protein, and/or presence of a MARK3 protein, and/or presence of antibodies directed against a MARK3 protein or a fragment comprising at least one epitope of the MARK3 protein. | 07-09-2009 |
| 20090280523 | Method for determining the molecular composition of a target tissue or another body structure, and its diagnostic applications - The present invention relates to a sampling instrument adapted for taking a sample in situ and in vivo or taking a sample ex vivo of a target tissue or body structure, in a maximum quantity of less than 10 | 11-12-2009 |
| 20100076054 | SENSIZITATION OF CANCER CELLS TO THERAPY USING SINA TARGETING GENES FROM THE 1P AND 19Q CHROMOSOMAL REGIONS - The invention relates to the identification of genes involved in resistance of cancer cells to therapy, to short nucleic acid molecules which inhibit the expression of these genes by RNA interference and to their use as adjuvant in cancer therapy, to sensitize cancer cells to conventional anticancer agents; the short nucleic acid molecules are double-stranded short interfering nucleic acid molecules including a sense and an antisense region, wherein the sense region includes a nucleotide sequence that is selected from the group consisting of: the sequences SEQ ID NO: 15, 11, 13, 14, 30, 31, 38, 46, 64 and 70 and the sequences having at least 70% identity, preferably at least 80% identity, more preferably at least 90% identity with the sequences, and the antisense region includes a nucleotide sequence that is complementary to the sense region. | 03-25-2010 |
| 20110294867 | SENSIZITATION OF CANCER CELLS TO THERAPY USING SINA TARGETING GENES FROM THE 1P AND 19Q CHROMOSOMAL REGIONS - The invention relates to the identification of genes involved in resistance of cancer cells to therapy, to short nucleic acid molecules which inhibit the expression of these genes by RNA interference and to their use as adjuvant in cancer therapy, to sensitize cancer cells to conventional anticancer agents; the short nucleic acid molecules are double-stranded short interfering nucleic acid molecules including a sense and an antisense region, wherein the sense region includes a nucleotide sequence that is selected from the group consisting of: the sequences SEQ ID NO: 15, 11, 13, 14, 30, 31, 38, 46, 64 and 70 and the sequences having at least 70% identity, preferably at least 80% identity, more preferably at least 90% identity with the sequences, and the antisense region includes a nucleotide sequence that is complementary to the sense region. | 12-01-2011 |
| 20120172753 | SURGICAL INSTRUMENT FOR MOLECULAR SAMPLING - The present disclosure relates to a surgical instrument for sampling molecules in an organ which can be accessed directly or via a surgical portal, including:
| 07-05-2012 |
| 20120322680 | USE OF MIRNAS AS BIOMARKERS IN GLIOMA DIAGNOSIS - The present application relates to the use of miRNAs as biomarkers in glioma diagnosis. It also relates to the use of miRNAs as biomarkers in glioblastoma and oligodendroglioma diagnosis. | 12-20-2012 |
| 20130330727 | INTRA-TISSUE IN VITRO DIAGNOSIS METHOD FOR DIAGNOSING BRAIN TUMOURS - An in vitro diagnostic method for diagnosing a brain tumour belonging to the group formed by two types of tumours: ODGs and GBMs, and for identifying the type of tumour, the method includes the measurement of at least two ratios of the expression levels of miRNA pairs extracted from a biological sample originating from a patient suspected of presenting one of the above-mentioned brain tumours. | 12-12-2013 |
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| 20100259189 | METHOD AND STRUCTURE OF FORMING A FLUORESCENT LIGHTING SYSTEM - A lighting system comprising a first plurality of fluorescent lamps ( | 10-14-2010 |
| 20120069609 | METHOD FOR LOWERING POWER LOSS AND CIRCUIT - A method and circuit for suppressing a bias current and decreasing power consumption. A current suppression circuit is coupled to a circuit element, which is capable of conducting the bias current. Coupling the current suppression circuit to the circuit element forms a node. In one operating mode, the current suppression circuit applies a voltage to the node in response to a heavy load. In another operating mode, the current suppression circuit lowers the voltage at the node in response to a light load or no load. Lowering the voltage at the node decreases the flow of bias current through the circuit element thereby lowering power loss. | 03-22-2012 |
| 20130193940 | METHOD OF FORMING A SWITCHED MODE POWER SUPPLY CONTROLLER DEVICE WITH AN OFF MODE AND STRUCTURE THEREFOR - At least one embodiment is directed to a semiconductor voltage controller comprising: a start-mode circuit associated with a start-mode; and an off-mode circuit associated with an off-mode, where the voltage controller can be configured to receive a feedback signal and an off-mode signal from a single input and provide an output voltage, where the voltage controller can be configured to be in the off-mode when the feedback signal is less than a skip level and the feedback signal is less than a HV control level, and where the voltage controller can be configured to be in start mode when the feedback signal is greater than HV control level and Vcc is below a Vcc-start. | 08-01-2013 |
| 20130272034 | METHOD OF FORMING A LOW POWER DISSIPATION REGULATOR AND STRUCTURE THEREFOR - In one embodiment, a method of forming a conditioning circuit includes configuring an output biasing network to provide a biasing voltage to an MOS transistor to enable the MOS transistor to operate in a saturated operating mode for input voltages that are less than a threshold voltage. | 10-17-2013 |
| 20130300387 | METHOD OF FORMING A SEMICONDUCTOR DEVICE AND STRUCTURE THEREOF - A power control circuit and method of formation is provided, which in one embodiment includes a low voltage detection circuit to process a rectified input voltage from at least one alternating current (AC) voltage source and to output a low voltage indication signal upon detection of an initiation of an increase in the rectified input voltage; and a driver circuit configured to receive a signal representative of the low voltage indication signal and, in response, to output a drive signal to the switch control input of the power switch to turn on the power switch. | 11-14-2013 |
| 20140247627 | CONVERTER AND METHOD - In accordance with an embodiment, a method for controlling a circuit includes controlling pulse width modulation on a primary side of a quasi-resonant controller to achieve continuous current mode operation from a synchronous rectification controller on a secondary side. | 09-04-2014 |
| 20150145496 | METHOD OF FORMING A SWITCHED MODE POWER SUPPLY CONTROLLER DEVICE WITH AN OFF MODE AND STRUCTURE THEREFOR - At least one embodiment is directed to a semiconductor voltage controller comprising: a start-mode circuit associated with a start-mode; and an off-mode circuit associated with an off-mode, where the voltage controller can be configured to receive a feedback signal and an off-mode signal from a single input and provide an output voltage, where the voltage controller can be configured to be in the off-mode when the feedback signal is less than a skip level and the feedback signal is less than a HV control level, and where the voltage controller can be configured to be in start mode when the feedback signal is greater than HV control level and Vcc is below a Vcc-start. | 05-28-2015 |
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| 20100317824 | POLYETHER DERIVATIVES OF SECONDARY HYDROXY FATTY ACIDS AND DERIVATIVES THEREOF - A compound that is a polyether of a saturated monobasic secondary hydroxyl fatty acid, preferably 12-hydroxy stearate, or a reaction product of the polyether with a polyhydric alcohol, a capping agent or a combination of both. Prepare the compound by contacting a saturated hydroxy monobasic fatty acid or derivative thereof with an alkoxide in the presence of a double metal cyanide catalyst such that a polyether of the fatty acid is formed. Optionally, preparation also includes a step of capping the polyether, or alternatively, contacting the polyether with a polyhydric alcohol. | 12-16-2010 |
| 20110105802 | Continuous Loop Flow Process For Polyether Polyol Production - The present disclosure relates, according to some embodiments, to compositions, apparatus, methods, and systems that may be used to produce polyols, for example, polyether polyols with a narrow range of molecular weights, with little if any unsaturated byproducts, in a sustained and/or continuous reaction, with efficient heat transfer, and/or at high production rates. For example, in some embodiments, teachings of the disclosure may be used to produce polyether polyols in a continuous loop flow process. A continuous loop flow process may be practiced such that heat is effectively transferred and/or product properties (e.g., range of molecular weights) are controllable. For example, a continuous loop flow process may use one or more continuous flow loops comprising a heat exchanger, a means to move material around each loop, inlets for catalyst, monomer, initiator or starter, and an outlet for polyol product. | 05-05-2011 |
| 20120283483 | METHOD FOR CONTINUOUSLY PRODUCING LOW EQUIVALENT WEIGHT POLYOLS USING DOUBLE METAL CYANIDE CATALYSTS - Polyether polyols having equivalent weights of up to 500 are continuously prepared in the presence of a double metal cyanide catalyst. A first step of the reaction is performed at a temperature of at least 1500 C, while controlling the hydroxyl content and unreacted alkylene oxide content of the reaction mixture to within certain ranges. A portion of that reaction mixture is withdrawn and permitted to react non-isothermally to consume the unreacted alkylene oxide. This process is highly efficient, does not result in catalyst deactivation, as is commonly seen in previous processes, and does not produce a significant ultra high molecular weight tail. | 11-08-2012 |
| 20130143977 | Ethylene Oxide/Propylene Oxide Polyether Polyols and Polyurethanes Made Therefrom - Copolymers of propylene oxide and ethylene oxide have an inner block that contains from 65-90 weight percent oxyethylene units and from 10 to 35 weight percent oxypropylene units. This block has a molecular weight of from 150 to 350. The copolymer has an outer block which contains at least 95 weight % oxypropylene units and from 0 to 5% oxyethylene units. The equivalent weight of the copolymer is from 800 to 2000. The copolymers are useful in making polyurethane foams that have unexpectedly high tensile and/or tear strengths. | 06-06-2013 |
| 20130289236 | ALKYLENE OXIDE POLYMERIZATION USING A DOUBLE METAL CYANIDE CATALYST COMPLEX AND A MAGNESIUM, GROUP 3 - GROUP 15 METAL OR LANTHANIDE SERIES METAL COMPOUND - Alkylene oxide polymerizations are performed in the presence of a double metal cyanide polymerization catalyst and certain magnesium, Group 3-Group 15 metal or lanthanide series metal compounds. The presence of the magnesium, Group 3-Group 15 metal or lanthanide series metal compound provides several benefits including more rapid catalyst activation, faster polymerization rates and the reduction in the amount of ultra high molecular weight polymers that are formed. The catalyst mixture is unexpectedly useful in making polyethers having low equivalent weights. | 10-31-2013 |
| 20140018459 | METHOD FOR PRODUCING SHORT-CHAIN POLYFUNCTIONAL POLYETHER POLYOLS UTILIZING SUPERACID AND DOUBLE-METAL CYANIDE CATALYSIS - A two stage alkoxlyation process for preparing a short-chain polyether polyol from a starter compound comprising from 3 to 9 hydroxyl groups and at least one alkylene oxide, wherein said starter compound has a hydroxy equivalent weight of from 22 to 90 Da. Said process comprises a first stage alkoxlyation using a superacid catalyst to prepare an oligomeric alkoxylated starter compound that is further alkoxylated to the short-chain polyether polyol of the invention in a second stage using a DMC catalyst. The process of the present invention may be performed continuously, in a batch, or semi-batch process. | 01-16-2014 |
| 20140058037 | Stabilizer Polymerization Process and Process for Making Polymer Polyols - A polymeric stabilizer is produced by copolymerizing an unsaturated polyether with an unsaturated low molecular weight monomer in a controlled radical polymerization. The polymeric stabilizer is useful for producing polymer polyol products via a mechanical dispersion process or an in situ polymerization process. | 02-27-2014 |
| 20140163197 | PROCESS FOR MAKING POLYETHER ALCOHOLS HAVING OXYETHYLENE UNITS BY POLYMERIZATION OF ETHYLENE CARBONATE IN THE PRESENCE OF DOUBLE METAL CYANIDE CATALYSTS - Ethylene carbonate is polymerized by itself or together with another cyclic monomer such as 1,2-propylene oxide in the presence of a double metal cyanide catalyst. Most of the ethylene carbonate adds to the chain to form a terminal carbonate group, which decarboxylates to produce a hydroxyethyl group at the end of the polymer chain. The polymerization of more ethylene carbonate onto the chain end results in the formation of poly(ethyleneoxy) units. Therefore, the process provides a method for making poly(ethyleneoxy) polymers without the need to polymerize ethylene oxide. The process is useful for making polyethers that are useful as water-absorbable polymers, surfactants and as raw materials for polyurethanes. The process is also useful for increasing the primary hydroxyl content of a polyether. | 06-12-2014 |
| 20150225504 | ALKYLENE OXIDE POLYMERIZATION USING A DOUBLE METAL CYANIDE CATALYST COMPLEX AND A MAGNESIUM, GROUP 3 - GROUP 15 METAL OR LANTHANIDE SERIES METAL COMPOUND - Alkylene oxide polymerizations are performed in the presence of a double metal cyanide polymerization catalyst and certain magnesium, Group 3-Group 15 metal or lanthanide series metal compounds. The presence of the magnesium, Group 3-Group 15 metal or lanthanide series metal compound provides several benefits including more rapid catalyst activation, faster polymerization rates and the reduction in the amount of ultra high molecular weight polymers that are formed. The catalyst mixture is unexpectedly useful in making polyethers having low equivalent weights. | 08-13-2015 |
| 20150376332 | Ethylene Oxide/Propylene Oxide Polyether Polyols and Polyurethanes Made Therefrom - Copolymers of propylene oxide and ethylene oxide have an inner block that contains from 65-90 weight percent oxyethylene units and from 10 to 35 weight percent oxypropylene units. This block has a molecular weight of from 150 to 350. The copolymer has an outer block which contains at least 95 weight % oxypropylene units and from 0 to 5% oxyethylene units. The equivalent weight of the copolymer is from 800 to 2000. The copolymers are useful in making polyurethane foams that have unexpectedly high tensile and/or tear strengths. | 12-31-2015 |
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| 20090022921 | Process for Manufacturing a Composite Ring - A process for manufacturing a composite block of closed geometry, in the form of a continuous ring, based on fibres and on a crosslinkable resin, by continuous winding and superposition of several layers of a tape of reinforcement fibres embedded in a matrix based on a composition comprising a crosslinkable resin. The process comprises from upstream to downstream, the following steps: producing a rectilinear arrangement ( | 01-22-2009 |
| 20100181006 | Method and Device for the Manufacture of a Composite Ring - Process for manufacturing a composite block of closed geometry, in the form of a continuous ring, based on reinforcing fibres and on a cross-linkable resin, by continuously winding in superposition a predetermined number Nc of layers of a tape of the reinforcing fibres embedded in a matrix based on a composition comprising the cross-linkable resin, the method comprising, from the upstream end downstream, the steps of: producing a rectilinear arrangement ( | 07-22-2010 |
| 20100260967 | Composite Laminated Product - Composite laminated product ( | 10-14-2010 |
| 20100307653 | Non-Pneumatic Elastic Wheel - Non-pneumatic resilient wheel ( | 12-09-2010 |
| 20110104428 | Composite Laminate Product - A laminated product ( | 05-05-2011 |
| 20110260525 | Non-Pneumatic Resilient Tire - Non-pneumatic resilient wheel ( | 10-27-2011 |
| 20150307981 | SURFACE SULFURIZATION OF A METAL BODY BY FLAME SPRAY PYROLYSIS - The surface of a body, in particular a metal reinforcer, at least the surface of which comprises a layer of metal referred to as surface metal capable of forming sulphides, is sulfurized. The metal can be chosen from copper, zinc and their alloys. The process comprises at least one stage of flame spray pyrolysis (FSP) of a sulphur-donating precursor, for example, thiophene, which generates hydrogen sulphide in the flame. The metal bodies or reinforcers thus treated can be directly adhesively bonded, without adhesion primer or addition of metal salt, such as a cobalt salt, to matrices of unsaturated rubber such as natural rubber. | 10-29-2015 |
| 20150352900 | READY-TO-USE METAL REINFORCEMENT THE SURFACE OF WHICH IS PROVIDED WITH METAL-SULFIDE NANOPARTICLES - A ready-for-use metal reinforcer, for example, of the wire or cord type, made of brass-coated carbon steel, is capable of adhering directly by vulcanization to a matrix of unsaturated rubber such as natural rubber. The surface of the reinforcer is provided with nanoparticles of at least one sulfide of a metal chosen from cobalt, copper, iron, zinc and the alloys comprising at least one of these elements. Such a reinforcer can be used as the reinforcing element of a finished article made of rubber, such as a tire. | 12-10-2015 |
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| 20090317378 | Antimicrobial composition and uses thereof - A composition for prophylactic and/or therapeutic medicinal applications, or plant protection applications, in particular for the control of microorganisms, either planktonic or organized in biofilms. The composition includes at least one ion selected from hypohalite, at least one compound selected from lactoferrin, lactoferrin peptide, lysozyme, immunoglobulins or a combination thereof, optionally hypothiocyanite, and optionally at least one growth factor. | 12-24-2009 |
| 20130064809 | Antimicrobial Composition and Uses Thereof - A composition for prophylactic and/or therapeutic medicinal applications, or plant protection applications, in particular for the control of microorganisms, either planktonic or organized in biofilms. The composition includes at least one ion selected from hypohalite, at least one compound selected from lactoferrin, lactoferrin peptide, lysozyme, immunoglobulins or a combination thereof, optionally hypothiocyanite, and optionally at least one growth factor. | 03-14-2013 |
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| 20090278740 | HYBRID POSITIONING METHOD AND DEVICE - The invention relates to a method of determining the position of an aircraft by combining inertial data with range data between the aircraft and satellites, in which: a) the range is stored in a FIFO memory so as make delayed range data available at the output from the memory; b) the delayed range data is combined with inertial data to obtain an estimate of position data for the aircraft; and c) a watch is maintained for the appearance of a fault in the range data, and when such a fault is detected, at least some of the data stored in the FIFO memory is modifying so as to be neutralized. | 11-12-2009 |
| 20100268414 | METHOD AND SYSTEM FOR ESTIMATING THE ANGULAR SPEED OF A MOBILE - A method of determining an angular velocity of an aircraft includes measuring the angular velocity using at least one gyro delivering a measured angular velocity signal affected by stochastic noise; measuring the angular acceleration of the aircraft using at least one accelerometer delivering a signal representing the angular acceleration of the aircraft; and using a filtering complementary in a frequency domain to combine a sum of the measured angular velocity signal and the angular acceleration signal so as to obtain a hybrid estimated angular velocity signal with reduced stochastic noise. | 10-21-2010 |
| 20110190964 | TURNING-STABILIZED ESTIMATION OF THE ATTITUDE ANGLES OF AN AIRCRAFT - The present invention relates to estimating the attitude angles of an aircraft ( | 08-04-2011 |
| 20110273324 | CONTINUOUS HIGH-ACCURACY LOCATING METHOD AND APPARATUS - Method and apparatus for locating an object ( | 11-10-2011 |
| 20110313703 | INERTIAL MEASUREMENT DEVICE AND AN AIRCRAFT INCLUDING SUCH A DEVICE - The present invention relates to an inertial measurement device secured to a structure of a vehicle for which it is desired to measure speeds and/or accelerations, the device comprising at least one piece of moving equipment in rotation about a stationary axis of rotation Y relative to the structure, said moving equipment including at least two measurement means having respective sensitivity axes X′ and Z′ that are mutually orthogonal and that lie in a plane perpendicular to the stationary axis of rotation Y, a motor for driving the moving equipment in rotation, means for determining the angular position of the moving equipment, means for responding to the angular position of the moving equipment to determine the projection of the measurements taken in the rotary frame of reference axes X′ and Z′ by the said at least two measurement means onto a vehicle frame of reference X and Z. | 12-22-2011 |
| 20140089542 | CHAINED INFORMATION EXCHANGE SYSTEM COMPRISING A PLURALITY OF MODULES CONNECTED TOGETHER BY HARDENED DIGITAL BUSES - A chained information exchange system ( | 03-27-2014 |
| 20150266591 | METHOD AND A DEVICE FOR ISSUING TERRAIN AVOIDANCE WARNINGS FOR A ROTARY WING AIRCRAFT - A method and a device ( | 09-24-2015 |
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| 20100179370 | DEVICE AND METHOD OF INERTING TOXIC MATERIALS BY PLASMA MELTING - The present invention pertains to a process and an device for plasma fusion inertizing of toxic materials, consisting of a melting vessel having an internal volume defined by walls. At least one non-transferred arc plasma source intended to generate a lance of plasma is inclined toward the lower part of the melting vessel and propagated along an axis of propagation situated outside of the vertical plane containing the normal to the wall at the point of intersection of said propagation axis with said wall so as to agitate the melting bath. The melting vessel is in fluid communication with the upstream part of a refining and pouring vessel and consists of an opening to which a non-transferred arc plasma source is connected, said source being mounted so as to emit a plasma lance to strike the refining bath directly in said upstream part. | 07-15-2010 |
| 20120193215 | METHOD AND APPARATUS FOR TREATING A SYNGAS - Treating a synthesis gas includes generating a plasma jet from a non-transferred arc torch having a main axis, the jet having a propagation axis substantially collinear with the torch main axis. The plasma torch is mounted on a feed enclosure. The syngas is received at an inlet port of the feed enclosure, downstream from the plasma torch and feeding the syngas so the flow encounters the plasma jet to mix the syngas and plasma jet in a distribution chamber. The mixture is propagated in a reactor downstream from the feed enclosure to convert the syngas into an outlet gas. The reactor is in communication in its upstream portion with the feed enclosure through a flared segment, and has a longitudinal axis that is substantially collinear with the propagation axis of the plasma jet. The outlet gas is extracted via an outlet port and particles are captured by a submerged conveyor. | 08-02-2012 |
| 20150021301 | SYSTEM FOR CONVERTING ELECTRIC ENERGY INTO THERMAL ENERGY - A system for transferring electrical energy to thermal energy which comprises two electrodes separated by a distance along the axis joining them and able to create field lines defining a zone of influence when subjected to a potential difference, an electrical power supply device for these electrodes, which is able to provide the potential difference, and a device for triggering an electric arc between these two electrodes. The triggering device comprises a device for emitting a laser pulse, a device for focusing the pulse at N focusing points situated in the zone of influence of the two electrodes, with a peak power density of the pulse per focusing point of greater than 1 GW/cm | 01-22-2015 |
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| 20100104581 | Methods for Diagnosing and Treating Graft Rejection and Inflammatory Conditions - The present invention relates to a method of diagnosis and/or prognosis of an inflammatory condition, which method comprises determining the expression level of TRIB1 in a biological sample of a patient, in particular in peripheral blood or in a biopsy of a diseased tissue. Methods for treating inflammatory conditions by modulating TRIB1 expression or activity are also described. | 04-29-2010 |
| 20100304988 | DIAGNOSTIC OF IMMUNE GRAFT TOLERANCE - The present invention concerns a method for the in vitro diagnosis of a graft tolerant phenotype, comprising: determining from a grafted subject biological sample an expression profile comprising, or consisting of, 8 genes, and optionally at least one among 41 further genes, identified in the present invention as differentially expressed between graft tolerant subjects and subjects in chronic rejection, optionally measuring other parameters, and determining the presence or absence of a graft tolerant phenotype from said expression profile and optional other parameters. Said method may further comprise, if said subject is diagnosed as a graft non-tolerant subject, diagnosing from the expression profile if said subject is developing chronic rejection. The invention further concerns kits and oligonucleotide microarrays suitable to implement said method. | 12-02-2010 |
| 20100305038 | DIAGNOSTIC OF IMMUNE GRAFT TOLERANCE USING TMTC3 GENE EXPRESSION LEVELS - The present invention concerns a method for the in vitro diagnosis or prognosis of a graft tolerant or graft non-tolerant phenotype, comprising: determining from a grafted subject biological sample an expression profile comprising TMTC3 gene, optionally measuring other parameters, and determining the presence of a graft tolerant or graft non-tolerant phenotype from said expression profile and optional other parameters, wherein said method does not comprise determining an expression profile comprising, in addition to TMTC3, the following 7 genes: BUB1B, CDC2, CHEK1, MS4A1, RAB30, RHOH, and SYNGR3. Said method may further comprise, if said subject is diagnosed as a graft non-tolerant subject, diagnosing from the expression profile if said subject is developing chronic rejection. The present invention also relates to a medicament comprising a TMTC3 protein, or a fragment, an analogue or an analogue fragment thereof, in particular for the treatment, prevention, delay or inhibition of graft rejection. | 12-02-2010 |
| 20110071071 | PSMB10: A DIAGNOSIS MARKER AND THERAPEUTIC TARGET OF CHRONIC REJECTION - The present invention relates to a method for diagnosing chronic graft rejection of a grafted organ in a subject from a biological sample of said subject, comprising: (a) determining in vitro an expression level value for PSMB10 in said subject biological sample, (b) comparing said value to at least one reference expression level value for PSMB10 in at least one reference sample, and (c) diagnosing if said subject is or not undergoing chronic rejection of said grafted organ. The invention also concerns a diagnostic kit or microarray for performing the method of the invention. The invention further concerns the medical use of proteasome inhibitors for treating chronic rejection. | 03-24-2011 |
| 20130006067 | METHOD AND DEVICE FOR DETERMINING A RISK OF GRAFT REJECTION - The invention relates to a method for determining a risk of permanent rejection of a graft after being transplanted to a recipient, said method being characterized in that it includes the following steps: (a) entering physiological/clinical characteristics of the recipient and the donor into a computation unit by means of an input interface, said characteristics including the gender of the recipient, the creatinine level of the graft donor when sampled, the age of the recipient at the time of the transplant,—the number of renal transplants previously received by the recipient,—a creatinine level of the recipient measured twice at at least one predetermined point in time after the transplant, a proteinuria level of the recipient measured at a predetermined point in time after the transplant, and the existence of an episode of permanent rejection of the transplant during the first year of the transplant; (b) determining the parameters on the basis of said characteristics; (c) combining said parameters so as to obtain a risk score of permanent rejection of the gait; and (d) analyzing said risk score so as to determine a risk of permanent rejection of a graft. | 01-03-2013 |
| 20130177925 | DETECTION OF ANTIGEN-SPECIFIC PERIPHERAL BLOOD MONONUCLEAR CELLS AND METHODS FOR DIAGNOSING IMMUNE DISORDERS - The present invention relates to a method for detecting the presence or the absence, and optionally quantifying and/or isolating, antigen-specific peripheral blood mononuclear cells. This method, which involves flow cytometry, is based on the use of a fluorescently-labeled antibody specifically recognizing peripheral blood mononuclear cells, and of fluorescently-labeled beads coated with at least one antigen that is specifically recognized by antigen-specific peripheral blood mononuclear cells. The method according to the invention is for example useful for diagnosing immune disorders such as transplant rejections and autoimmune disorders. | 07-11-2013 |
| 20140308281 | ANTIBODIES DIRECTED AGAINST THE ALPHA CHAIN OF IL7 RECEPTOR - THEIR USE FOR THE PREPARATION OF DRUG CANDIDATES - The invention concerns antibodies directed against CD127, I.e. the alpha chain of the receptor for interleukin7 (IL-7), especially the receptor for human IL-7 expressed on human cells (designated human IL-7R alpha or IL-7Ra) or the TSLP receptor. The antibodies of the invention have cytotoxic activity against CD127 positive cells. The invention also relates to the use of these antibodies in order to deplete subpopulations of T lymphocytes as a result of cytotoxic action of the antibodies, through ADCC and optionally through CDC. Accordingly the invention concerns the use of the antibodies in the treatment of transplant rejection, autoimmune diseases, allergic diseases, lymphoma or cancer when these pathologies are associated with CD127 positive cells. | 10-16-2014 |
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| 20090236880 | Adjustable Vehicle Seat - A seat assembly is provided for use in a vehicle interior, and includes a frame and lower and upper bracket assemblies. The lower bracket assembly is connected to a lower portion of the frame, and selectively moves the frame in a longitudinal direction with respect to the vehicle interior. The upper bracket assembly is connected to an upper portion of the frame, and has a slot which receives a selector pin for selectively pivoting the upper portion of the frame with respect to the lower portion of the frame. A moveable linkage is connected to the upper bracket assembly and moves the selector pin for adjusting between different passenger seating positions. An adjustment mechanism includes a lever for moving the moveable linkage via a cable. The seat assembly can include a deployable storage bin positioned between the bulkhead and a seat surface. | 09-24-2009 |
| 20090243325 | Vehicle Seat Assembly And Method For Use Thereof - A seat row assembly is provided, having a first rail and a first seat movably connected to the first rail. A second seat is moveable between a first position and a second position, such that the second seat in its second position does not occupy the same space as in its first position. The first seat is configured to selectively move from a first position into a second position, in which it occupies space occupied by the second seat in its respective first configuration. A second rail, perpendicular to the first rail, is movably connected to the first rail such that the first seat is selectively movable along both the first rail and the second rail. The seats may be configured to fold to a collapsed configuration. A method of allowing access to a third row of seats in a vehicle having a second row of seats is also provided. | 10-01-2009 |
| 20100123344 | SELF-RETRACTING HEADREST ASSEMBLY WITH DIVIDED HEADREST - A headrest assembly for a seat having a seat back and a seat bottom is provided that includes a headrest having first and second divided headrest portions. First and second articulated arms are pivotably mounted with respect to the seat back in a scissor arrangement and supporting the first and second headrest portions, respectively. Each of the articulated arms has a respective distal portion operatively connected to the seat bottom, preferably with flexible cables and a forked element. The headrest assembly is configured so that the headrest portions pivot to adjacent, use positions when the seat bottom is subjected to at least a predetermined load and to pivot back to separated, non-use positions when the seat bottom is not subject to at least the predetermined load. | 05-20-2010 |
| 20100218345 | DOOR ASSIST ASSEMBLY FOR BEING GRASPED BY A USER OF A VEHICLE - A door assembly for a vehicle includes a door panel, a primary assist handle, a secondary assist handle, and a first and second extension. The primary assist handle and the secondary assist handles are configured for being grasped by the user of the vehicle. A first extension extends from the door panel. A second extension extends from a second mounting portion of the secondary assist handle, in spaced relationship to the first extension. The extensions pivotally support ends of the primary assist handle. The primary assist handle pivots relative to each of the extensions and the door of the vehicle, between a retracted position and an extended position. A first mounting portion of the secondary assist handle pivotally extends from the door panel. | 09-02-2010 |
| 20110204681 | VEHICLE DOOR ASSEMBLY - A vehicle includes a vehicle body and a vehicle door assembly. The door assembly is selectively movable with respect to the body between open and closed positions. The door assembly includes an upper portion and a lower portion. The lower portion is selectively movable relative to the upper portion such that the height of the door above the ground is selectively variable. | 08-25-2011 |
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| 20100176675 | ELECTRIC ROTATING MACHINE, MAINLY FOR THE STARTER OF AN AUTOMOTIVE VEHICLE - A DC electric rotating machine, mainly for the starter of an automotive vehicle. The machine includes a stator including a wound structure forming a plurality of poles extending along the circumference of the stator, a rotor, and a set of brushes adapted for the electric supply of the rotor by commutation of the electric current in sections of the rotor. The wound structure of the stator includes a plurality of slots between two central parts of consecutive poles of the stator, these slots being formed in a magnetic body of the stator. At least one of the slots including at least one conducting segment forming a winding of an electrical coil. | 07-15-2010 |
| 20100176677 | ELECTRIC ROTATING MACHINE WITH SALIENT POLES - A DC electric rotating machine, such as a starter of an automotive vehicle, includes a stator with salient poles having at least four poles distributed uniformly over the circumference of the stator, a rotor disposed inside the stator, a set of brushes adapted for the electric supply of the rotor, and at least two geometrically opposed salient poles. Each pole includes at least one substantially radial slot in a plane parallel to the axis of rotation of the rotor and preferably passes through the axis of the rotor. By minimizing the reaction fields of the armature, utilization of the magnetic material of the parts of the stator is balanced and a harmful armature reaction effect, which increases saturation of the polar parts of the inductor and which leads to reduction in the driving magnetic torque, is mitigated. | 07-15-2010 |
| 20140091665 | ELECTRIC ROTATING MACHINE, MAINLY FOR STARTER OF AUTOMOTIVE VEHICLE - A DC electric rotating machine, mainly for the starter of an automotive vehicle. The machine includes a stator including a wound structure forming a plurality of poles extending along the circumference of the stator, a rotor, and a set of brushes adapted for the electric supply of the rotor by commutation of the electric current in sections of the rotor. The wound structure of the stator includes a plurality of slots between two central parts of consecutive poles of the stator, these slots being formed in a magnetic body of the stator. At least one of the slots including at least one conducting segment forming a winding of an electrical coil. | 04-03-2014 |
