Patent application number | Description | Published |
20150268683 | DIRECT LOAD CONTROL FREQUENCY REGULATION SUPPORT SYSTEM - A plurality of interactive electrical loads defines an aggregation connected with an electrical power grid. A scheduler generates a baseline power consumption schedule for the aggregation, determines frequency regulation capacity of the aggregation, and controls actual power consumption of the aggregation based on the baseline power consumption and an Automated Generation Control (AGC) signal of the electrical power grid to operate the aggregation as an ancillary frequency control device of the electrical power grid with the determined frequency regulation capacity. The controlling may comprise generating baseline dispatch signals for implementing the baseline consumption schedule, adjusting the baseline dispatch signals based on the AGC signal to generate adjusted dispatch signals, transmitting the adjusted dispatch signals to the plurality of interactive electrical loads defining the aggregation, and generating an AGC response log based on differences between the adjusted dispatch signals and the baseline dispatch signals. | 09-24-2015 |
20150295402 | METHOD AND SYSTEM FOR USING DEMAND SIDE RESOURCES TO PROVIDE FREQUENCY REGULATION USING A DYNAMIC ALLOCATION OF ENERGY RESOURCES - In a direct load control system supporting frequency control of an electrical grid, loads are grouped into a plurality of load aggregations based on electrical power draw characteristics of the loads, e.g. power draw magnitude characteristic and transient slew rate. A best-fit dispatch signal is generated for each load aggregation to match a desired load response with a sum of predicted load responses of the aggregations each operating in accord with its best-fit dispatch signal. For each load aggregation, its best-fit dispatch signal is communicated to the loads of the load aggregation, and the loads of the load aggregation are operated in accord with the best-fit dispatch signal communicated to the loads. The desired load response may be generated based on historical Automatic Generation Control (AGC) signal data and at least one of (1) a weather forecast and (2) daily, weekly, and seasonal cycles. | 10-15-2015 |
20150295405 | USING DEMAND SIDE RESOURCES TO PROVIDE FREQUENCY REGULATION - In a direct load control system supporting frequency control of an electrical grid, at each electrical load of an aggregation of loads, a load status report is generated comprising an urgency value and a power level. At an aggregation dispatch controller, a dispatch signal is generated based on the generated load status reports and information indicative of electrical frequency. At each electrical load of the aggregation, the load is operated at the reported power level if the reported urgency value satisfies the dispatch signal and is not operated at the reported power level if the reported urgency value does not satisfy the dispatch signal. | 10-15-2015 |
Patent application number | Description | Published |
20130190116 | MODULAR HYDRAULIC TENSIONER WITH RATCHET - A modular tensioner system for an engine including a modular tensioner and an application specific carrier ( | 07-25-2013 |
20150204341 | SPEED SENSOR INSERT WITH BEARING SPACER INDEXING FOR A TURBOCHARGER - Modern turbochargers use speed sensors to determine the shaft speed during operation. In order to replace a speed sensor in a turbocharger with journal bearings separated by a spacer, the tip of the speed sensor must be withdrawn from a window in the spacer and replaced through the same window. If the spacer turns while the sensor is removed, then the window will be out of alignment with the axis of the sensor and the sensor cannot be re-inserted through the window. An insert is provided for preventing rotation of the window in the spacer while the sensor is withdrawn. The insert also prevents wear to the speed sensor from the fluctuating contact forces transmitted from the shaft to the bearing spacer and subsequently to the speed sensor. Accordingly, the durability of the speed sensor is improved, the rate of failure and need for sensor replacement, is reduced. | 07-23-2015 |
20150233299 | TURBOCHARGER SHAFT SEAL | 08-20-2015 |
20150285132 | ACTUATOR ROD SEALING SYSTEM - Turbochargers use actuators to control wastegate valve or VTG vane position to control turbine wheel power. Components of such actuators are susceptible to damage when exposed to foreign liquids, solids and debris. To prevent such ingress, boot seals at the actuator shaft can provide a tortuous path for air aspiration and expulsion from the volume inside the actuator boot is provided at one or more interfaces in the actuator system. Such a path can also prevent ingress of undesired liquids, solid and debris, which can affect actuator performance material. In one arrangement, a tortuous pathway is provided between a boot seal holder and another actuator component. In another arrangement, a tortuous pathway is provided between the actuator shaft and an end portion of a boot seal. | 10-08-2015 |
20150300362 | METHOD FOR JOINING BEARING HOUSING SEGMENTS OF A TURBOCHARGER INCORPORATING AN ELECTRIC MOTOR - A bearing housing ( | 10-22-2015 |
Patent application number | Description | Published |
20110017540 | DIFFERENTIAL ASSEMBLY INCLUDING DIFFERENTIAL LOCK AND BLOCKING MEMBER - A differential assembly includes an axle, a differential, a differential lock, a blocking member, and a pump. The differential is coupled with the axle and configured to facilitate operation of the axle at an axle speed. The differential lock is associated with the differential and movable between a locked position and an unlocked position. The blocking member is associated with the differential lock and is movable between a blocking position and a non-blocking position. When the blocking member is in the blocking position, the differential lock is inhibited from moving to the locked position. The pump includes an outlet in fluid communication with the blocking member. The pump is operably coupled with the axle and is configured to facilitate movement of the blocking member into the blocking position when the axle speed is above a threshold speed. Vehicles including a differential assembly are also provided. | 01-27-2011 |
20110241325 | NET STRUCTURE FOR A VEHICLE - A vehicle includes a roll cage and a net structure attached to the roll cage. The roll cage at least partially defines a protected area and at least partially defines an access opening communicating with the protected area. The net structure is selectively configurable in a lowered, closed configuration to at least inhibit passage of an operator of the vehicle through the access opening, and is further selectively configurable in a generally rolled-up, open configuration to facilitate passage of an operator of the vehicle through the access opening. | 10-06-2011 |
20140216832 | VEHICLE INCLUDING MOUNT DEVICES FOR COUPLING A SUB-FRAME WITH A MAIN FRAME - A vehicle includes a frame, an engine, and a plurality of mount devices. The frame includes a main frame and a sub-frame attached to the main frame. The engine is attached to the sub-frame. | 08-07-2014 |
Patent application number | Description | Published |
20140001131 | LOOSE ITEM DISPLAY FIXTURE | 01-02-2014 |
20140007403 | SHELF-TYPE DISPLAY FIXTURE - A display fixture for displaying an object, such as bound media, includes a base having a shelf engaging portion that mounts to an underside of a shelf, a brush support portion and a brush having an elongated spine. The elongated spine is received by the brush support portion and a plurality of flexible bristles that depend downwardly from the elongated spine. The distal ends of the plurality of flexible bristles are free from contacting the base, and when not engaged with the object, the flexible bristles are oriented substantially normal to the shelf. | 01-09-2014 |
20140021315 | PRODUCT DISPLAY FIXTURE - A display fixture includes a fixed component including a product receiving portion and an elongated spine portion, a first adjustable component insertably engaged with the elongated spine portion and including a product receiving portion and an adjustment portion, a second adjustable component insertably engaged with the elongated spine portion and including a product receiving portion and an adjustment portion, a third adjustable component insertably engaged with the elongated spine portion and including a product receiving portion and an adjustment portion. The first adjustable component operates to slidably adjust a distance between the product receiving portion of the fixed component and the product receiving portion of the first adjustable component, while the second adjustable component and the third adjustable component operate to slidably adjust a distance between the product receiving portion of the second adjustable component and the product receiving portion of the third adjustable component. | 01-23-2014 |
20140374556 | DISPLAY FIXTURE HAVING A DISPLAY HOOK - A display fixture includes a cross support mounted to a display structure. The cross support includes a cross bar having a plurality of holes extending through at least a top of the cross bar. The holes are spaced apart from each other across a length of the cross bar. The display fixture also includes at least one display hook having three downwardly depending mounting members. The at least display hook is mounted to the cross bar by engaging two of the three downward depending mounting members with two holes in the cross bar. | 12-25-2014 |
20150102001 | Retail Fixtures - A display fixture has a bin with multiple sections. A clip attached to a back panel of the bin has an aperture for receiving a fastener to fasten the bin to a peg board. A back support is mounted to the bin and has a downwardly extending leg that is sized to fit between the peg board and a back surface of a base that the display fixture is seated upon. The bin includes a lower tier of product sections defined in part by a front panel and has a lower sign support with two legs attached to the front panel and a lower label holder connected between the two legs such that there is an open space defined between the two legs and between a top of the front panel and a bottom of the lower label holder. The bin also includes an upper tier of product sections. | 04-16-2015 |
20150216327 | DISPLAY FIXTURE HAVING A DISPLAY HOOK - A display fixture includes a cross support mounted to a display structure. The cross support includes a cross bar having a plurality of holes extending through at least a top of the cross bar. The holes are spaced apart from each other across a length of the cross bar. The display fixture also includes at least one display hook having three downwardly depending mounting members. The at least display hook is mounted to the cross bar by engaging two of the three downward depending mounting members with two holes in the cross bar. | 08-06-2015 |
20160073794 | MODULAR DISPLAY UNIT - A display unit includes an upper component that has a top panel, four side panels having bottom edges, exterior surfaces and interior surfaces that define a hollow interior. A base frame includes a lower portion having an outer periphery and an upper portion that extends upwardly from a top of the lower portion and has an outer periphery. Four corner members are coupled to and extend inwardly from the interior surfaces of the upper component and are positioned at a distance from the bottom edges of the four side panels. The four corner members engage with a top of the upper portion of the base frame such that the bottom edges of the four side panels of the upper component are spaced apart from the top of the lower portion of the base frame to expose a section of the upper portion of the base frame. | 03-17-2016 |
20160113395 | MOBILE CART - A mobile cart includes a cabinet supported by a plurality of wheels, a countertop located on top of the cabinet, an upper trim assembly completely surrounding an upper portion of the cabinet and being spaced apart from the cabinet by a space, a lower trim assembly at least partially surrounding a lower portion of the cabinet and being spaced apart from the cabinet by a space and a marketing sign held to a front panel of the cabinet. The upper edge of the marketing sign is located in the space between a front member of the upper trim assembly and a front panel of the cabinet. The lower edge of the marketing sign is located in the space between a front member of the lower trim assembly and the front panel of the cabinet. | 04-28-2016 |
Patent application number | Description | Published |
20130142571 | Screed plate arrangement and method of attaching a screed plate - Asphalt paving machine includes screed assembly, plurality of lower and upper plate fasteners, and upper and lower screed plates, each having openings, and an electric heater at least partially disposed between the plates. Upper and lower plate fasteners extend into openings of the respective upper and lower screed plates and bores of a frame portion of the screed assembly to couple the plates to the frame portion. The upper plate fasteners couple the upper screed plate to the frame portion independently of the lower screed plate, so the lower plate is displaceable from the upper plate and the frame portion. | 06-06-2013 |
20140186115 | Paving Machine with Automatically Adjusting Paver Tractor and Screed - A paving machine including an adjustable screed assembly is provided. Actuators adjust the screed assembly into the plurality of different configurations. Sensors sense a respective configuration parameter indicative of the configuration of the screed assembly. A controller is configured to save a first set of parameters including the configuration parameters and save a second set of parameters including the configuration parameters in response. The controller is configured to recall one of the first set or second set of parameters, and adjust automatically the configuration of the screed assembly to correspond to the configuration parameters included in the recalled first set or second set of parameters. | 07-03-2014 |
20140301784 | SCREED WALKWAY - A walkway for a screed includes a main walkway and an extender walkway coupled to the main walkway and an extender frame of the screed. The extender walkway is slidable relative to the main walkway along a sliding direction. Further, the extender walkway and the extender frame are pivotable relative to each other about a walkway pivot axis, the walkway pivot axis being substantially perpendicular to the sliding direction. | 10-09-2014 |
20140377003 | SCREED FRAME AND PLATE - A screed includes a frame and a plate. The frame includes a bottom surface and a plurality of mounting members. The plurality of the mounting members project from the bottom surface. At least one of the plurality of the mounting members is longitudinally and transversely offset relative to the other mounting members. Further, the plate is coupled to the frame by the plurality of the mounting members. | 12-25-2014 |
Patent application number | Description | Published |
20110308625 | System and Method for Transporting Hydrocarbons - Methods and systems are provided for producing hydrocarbons from production fluids that have water as an external phase. A method for transporting a hydrocarbon through a pipeline includes injecting water into a production stream at a production center. The production stream includes a hydrocarbon, and the water injection forms a transportation stream that includes a water external phase. The transportation stream is flowed through a transportation line to a surface facility, wherein the transportation line comprises a plurality of static mixers spaced at intervals along the transportation line. | 12-22-2011 |
20120255737 | APPARATUS, SYSTEM, AND METHODS FOR GENERATING A NON-PLUGGING HYDRATE SLURRY - Provided are apparatus, systems, and methods for generating a non-plugging hydrate slurry. The apparatus, systems, and methods for generating a hydrate slurry are useful for transport and/or production of wellstream hydrocarbons in subsea and arctic environments. The present invention provides methods of seeded or unseeded methods of making dry hydrates. Dry hydrates are made with or without the aid of chemicals and, preferably, with minimum use of rotating or other energized equipment. | 10-11-2012 |
20120322693 | SYSTEM AND METHOD FOR CREATING FLOWABLE HYDRATE SLURRIES IN PRODUCTION FLUIDS - Methods and systems are provided for producing hydrocarbons from production fluids that have water as an external phase. An exemplary embodiment provides a method that comprises producing a production fluid having water as the external phase and injecting an amount of a thermodynamic hydrate inhibitor into the production fluid, wherein the amount is adjusted to allow hydrate formation to occur while retaining liquid water as the external phase. The water and thermodynamic hydrate inhibitor may be separated from the production fluid and a purified hydrocarbon stream may be produced. | 12-20-2012 |
20130025873 | Protecting A Fluid Stream From Fouling - Embodiments described herein provide a system and methods for protecting a fluid stream from fouling using particles that include phase change materials. In an example, the particles are injected into the fluid stream and release energy at a selected temperature, which may warm the fluid stream. | 01-31-2013 |
20130312980 | Injecting A Hydrate Slurry Into A Reservoir - A method and systems are provided for injecting a hydrate slurry into a reservoir. The method includes combining gas and water within a subsea simultaneous water and gas (SWAG) injection system. The method also includes forming a hydrate slurry from the gas and the water, and injecting the hydrate slurry into a reservoir. | 11-28-2013 |
Patent application number | Description | Published |
20100211071 | METHODS AND DEVICES FOR TREATING HALLUX VALGUS - The various embodiments disclosed herein relate to implantable devices for the treatment of hallux valgus. More specifically, the various embodiments include devices having dynamic tensioning components or heat shrinkable components configured to urge two metatarsals together to treat a bone deformity. | 08-19-2010 |
20110077656 | METHODS AND DEVICES FOR TREATING A STRUCTURAL BONE AND JOINT DEFORMITY - The various embodiments disclosed herein relate to implantable devices for the treatment of a structural bone and deformity. More specifically, the various embodiments include systems, devices, and methods for implantation of a flexible or tension band for treating such a deformity, including hallux valgus. | 03-31-2011 |
20110178557 | METHODS AND DEVICES FOR TREATING HALLUX VALGUS - The various embodiments disclosed herein relate to implantable devices for the treatment of structural bone and joint deformity, including hallux valgus. More specifically, the various embodiments include systems, devices, and methods for implantation of a flexible or tension band for treating such deformity. | 07-21-2011 |
20120172936 | METHODS AND DEVICES FOR TREATING A SYNDESMOSIS INJURY - The various embodiments disclosed herein relate to implantable devices for the treatment of syndesmosis injuries. More specifically, the various embodiments include systems, devices, and methods for implantation of an implantable device having at least one bone anchor for treating such injuries. | 07-05-2012 |
20120330322 | METHODS AND DEVICES FOR TREATING A STRUCTURAL BONE AND JOINT DEFORMITY - The various embodiments disclosed herein relate to implantable devices for the treatment of a structural bone and deformity. More specifically, the various embodiments include systems, devices, and methods for implantation of a flexible or tension band for treating such a deformity, including hallux valgus. | 12-27-2012 |
Patent application number | Description | Published |
20100115715 | Booster Pump System for Pool Applications - Assemblies and methods for a booster pump used in a pool cleaning/filtration system are provided. An exemplary booster pump assembly is adapted to increase the water pressure of water flow for use in a pool cleaning system. The booster pump includes a front housing defining a substantially circular geometry having an inlet positioned substantially in the center of the front housing and extending axially outward with respect to the front housing. The booster pump also includes an outlet extending substantially laterally with respect to the front housing. The front housing and the rear housing form an enclosure for positioning of an impeller. The inlet and the outlet are each coupled to conduits having substantially similar flow diameters, and the water passing through the outlet at an increased water pressure is sufficient to make operable a positive pressure pool cleaner. Advantageous support structures and drain plug configurations are also provided. | 05-13-2010 |
20110280744 | Universal Mount For A Variable Speed Pump Drive User Interface - Disclosed herein is a user interface that can be universally mounted to a combination variable speed pump and a drive assembly therefor. The user interface is universally configured to be selectively mounted to the drive assembly and/or to an environmental surface that is remotely located from the drive assembly. The user interface is universally configured to be selectively mounted to the drive assembly in any one of a plurality of available positions relative thereto. | 11-17-2011 |
20110286859 | Pump Controller With External Device Control Capability - A variable speed motor controller senses the electrical load on the motor in turning a pump. An output of the controller may be used to trigger a vent valve or power to the motor may be cut if the load level indicates a restricted flow of fluid into the suction side of the pump, such as would be caused by drain occlusion in a swimming pool. A sensor in communication with the suction side of the pump ascertains a vacuum/pressure level present and may be used to verify that an intended operational state for the variable speed motor and the pump is actualized, otherwise anomaly processing is invoked. This pressure/vacuum monitoring may be conducted through speed changes of the motor/pump. | 11-24-2011 |
20130028755 | Booster Pump System for Pool Applications - Assemblies and methods for a booster pump used in a pool cleaning/filtration system are provided. An exemplary booster pump assembly is adapted to increase the water pressure of water flow for use in a pool cleaning system. The booster pump includes a front housing defining a substantially circular geometry having an inlet positioned substantially in the center of the front housing and extending axially outward with respect to the front housing. The booster pump also includes an outlet extending substantially laterally with respect to the front housing. The front housing and the rear housing form an enclosure for positioning of an impeller. The inlet and the outlet are each coupled to conduits having substantially similar flow diameters, and the water passing through the outlet at an increased water pressure is sufficient to make operable a positive pressure pool cleaner. Advantageous support structures and drain plug configurations are also provided. | 01-31-2013 |
20130146525 | Strainer Basket And Related Methods Of Use - Improved strainer members for use with pump assemblies and/or fluid systems (e.g., fluid circulation systems) are provided. The present disclosure provides for advantageous strainer members that strain and/or filter fluids in fluid systems (e.g., recreational bodies of water). More particularly, the present disclosure provides for strainer members (e.g., strainer baskets) that include features that improve performance characteristics. Strainer members with an improved ability to resist degradation of pump hydraulic performance when loaded with debris, and/or an improved ability to remove air pockets trapped under the strainer cover at low flow rates are disclosed. | 06-13-2013 |
Patent application number | Description | Published |
20120167331 | SUCTION NOZZLE WITH OBSTACLE SENSOR - A suction nozzle for a vacuum cleaner includes one or more sensor(s) to sense an obstacle near or proximate to the suction nozzle. A side brush can be rotated or a working air path can be diverted based on a signal from the sensor(s). | 07-05-2012 |
20130180055 | METHOD OF CLEANING A CARPET SEGMENT - The embodiments of the invention relate to methods of use of an extraction cleaning machine for cleaning a carpet segment of relatively rectangular configuration defined by a first edge, a second edge and opposite side edges comprising (a) applying a liquid cleaning solution to the carpet segment in a narrow band that extends between the side edges and moves between the first and second edges and (b) applying suction in a narrow band that extends between the side edges and moves between the first and second edges. Acts (a) and (b) can be repeated and performed in a predetermined sequence to improve the cleaning effectiveness of an extraction cleaning machine. | 07-18-2013 |
20140263314 | CONTAINER AND CAP ASSEMBLY - A cap for closing an opening in a container, the container having a top wall in which the opening is formed, a bottom wall, and at least one container side wall extending between the top wall and the bottom wall defining a cavity for storing a material for dispensing through the cap includes an end face having at least one fluid inlet adapted to allow air to flow through the cap and at least one fluid outlet, separate from the at least one fluid inlet, adapted to allow liquid to flow through the cap, a side wall extending from the end face, and a retaining element provided on at least a portion of the side wall. | 09-18-2014 |
20150108244 | APPARATUS FOR CLEANING A SURFACE - An apparatus for cleaning a surface includes a liquid delivery system for storing cleaning liquid and delivering the cleaning liquid to the surface to be cleaned, and an indicator system that is operably coupled with the liquid delivery system to indicate an operational status to the user operating the apparatus. The indicator system can include a light emitter that illuminates when an operational status is detected. The light emitter can illuminate the container storing cleaning liquid. | 04-23-2015 |
Patent application number | Description | Published |
20150322039 | 2-PYRIDYLAMINO-4-NITRILE-PIPERIDINYL OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-pyridylamino-4-nitrile-piperidinyl compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridylamino-4-nitrile-piperidinyl compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 11-12-2015 |
20150322040 | 3-ESTER-4 SUBSTITUTED OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 3-ester-4-substituted compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 3-ester-4-substituted compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 11-12-2015 |
20150322041 | 2-PYRIDYLOXY-4-NITRILE-4-SUBSTITUTED OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-pyridyloxy-3-nitrile-4-substituted compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyloxy-3-nitrile-4-substituted compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 11-12-2015 |
20160016935 | 2-PYRIDYLOXY-4-ETHER OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-pyridyloxy-4-ether compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyloxy-4-ether compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 01-21-2016 |
20160102073 | 2-HYDROXYMETHYL-SUBSTITUTED OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-hydroxymethyl compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 04-14-2016 |
Patent application number | Description | Published |
20120149677 | ETHER BENZOTRIAZOLE DERIVATIVES - The present invention is directed to ether benzotriazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved. | 06-14-2012 |
20150252033 | 2-PYRIDYLOXY-3-ESTER-4-NITRILE OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-pyridyloxy-3-ester-4-nitrile compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyloxy-3-ester-4-nitrile compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 09-10-2015 |
20150291558 | 2-PYRIDYLOXY-3-SUBSTITUTED-4-NITRILE OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-pyridyloxy-3-substituted-4-nitrile compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyloxy-3-substituted-4-nitrile compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 10-15-2015 |
20150322040 | 3-ESTER-4 SUBSTITUTED OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 3-ester-4-substituted compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 3-ester-4-substituted compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 11-12-2015 |
20150322041 | 2-PYRIDYLOXY-4-NITRILE-4-SUBSTITUTED OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-pyridyloxy-3-nitrile-4-substituted compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyloxy-3-nitrile-4-substituted compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 11-12-2015 |
Patent application number | Description | Published |
20120135977 | ETHER BENZOTRIAZOLE DERIVATIVES - The present invention is directed to ether benzotriazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved. | 05-31-2012 |
20130102619 | 2-PYRIDYLOXY-4-NITRILE OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-pyridyloxy-4-nitrile compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyl-oxy-4-nitrile compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 04-25-2013 |
20130116272 | HETEROCYCLIC FUSED PHENANTHROLINONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS - The present invention is directed to heterocyclic fused phenanthrolinone compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor. | 05-09-2013 |
20140066443 | AMINOMETHYL BIARYL BENZOTRIAZOLE DERIVATIVES - The present invention is directed to aminomethyl biaryl benzotriazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved. | 03-06-2014 |
20140088112 | ALKYNE BENZOTRIAZOLE DERIVATIVES - The present invention is directed to alkyne benzotriazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved. | 03-27-2014 |
20140243368 | PIPERIDINYL ALKYNE OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to piperidinyl alkyne compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the piperidinyl alkyne compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 08-28-2014 |
20150252033 | 2-PYRIDYLOXY-3-ESTER-4-NITRILE OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-pyridyloxy-3-ester-4-nitrile compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyloxy-3-ester-4-nitrile compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 09-10-2015 |
20150291558 | 2-PYRIDYLOXY-3-SUBSTITUTED-4-NITRILE OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-pyridyloxy-3-substituted-4-nitrile compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyloxy-3-substituted-4-nitrile compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 10-15-2015 |
20150322039 | 2-PYRIDYLAMINO-4-NITRILE-PIPERIDINYL OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-pyridylamino-4-nitrile-piperidinyl compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridylamino-4-nitrile-piperidinyl compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 11-12-2015 |
20160068510 | HYDROXY-SUBSTITUTED OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to hydroxy compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 03-10-2016 |
20160102073 | 2-HYDROXYMETHYL-SUBSTITUTED OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-hydroxymethyl compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 04-14-2016 |