Patent application number | Description | Published |
20100086945 | DIAGNOSTIC METHOD FOR DISEASES BY SCREENING FOR HEPCIDIN IN HUMAN OR ANIMAL TISSUES, BLOOD OR BODY FLUIDS AND THERAPEUTIC USES THEREFOR - The present invention concerns methods and kits for diagnosing a disease condition characterized by non-physiological levels of hepcidin protein, including prohepcidin and fragments thereof, comprising obtaining a tissue or fluid sample from a subject; contacting the sample with an antibody or fragment thereof that specifically binds to a polypeptide corresponding to the amino acid sequence between and including amino acids 25 and 49 of a hepcidin precursor protein, and quantifying the hepcidin precursor level using an assay based on binding of the antibody and the polypeptide; wherein the non-physiological level of prohepcidin is indicative of the disease condition. The present invention also concerns diagnostic methods and kits for applications in genetic technological approaches, such as for overexpressing or downregulating hepcidin. | 04-08-2010 |
20110275099 | DIAGNOSTIC METHOD FOR DISEASES BY SCREENING FOR HEPCIDIN IN HUMAN OR ANIMAL TISSUES, BLOOD OR BODY FLUIDS AND THERAPEUTIC USES THEREFOR - The present invention concerns methods and kits for diagnosing a disease condition characterized by non-physiological levels of hepcidin protein, including prohepcidin and fragments thereof, comprising obtaining a tissue or fluid sample from a subject; contacting the sample with an antibody or fragment thereof that specifically binds to a polypeptide corresponding to the amino acid sequence between and including amino acids 25 and 49 of a hepcidin precursor protein, and quantifying the hepcidin precursor level using an assay based on binding of the antibody and the polypeptide; wherein the non-physiological level of prohepcidin is indicative of the disease condition. The present invention also concerns diagnostic methods and kits for applications in genetic technological approaches, such as for overexpressing or downregulating hepcidin. | 11-10-2011 |
20110287448 | DIAGNOSTIC METHOD FOR DISEASES BY SCREENING FOR HEPCIDIN IN HUMAN OR ANIMAL TISSUES, BLOOD OR BODY FLUIDS AND THERAPEUTIC USES THEREFOR - The present invention concerns methods and kits for diagnosing a disease condition characterized by non-physiological levels of hepcidin, comprising obtaining a tissue or fluid sample from a subject; contacting the sample with an antibody or fragment thereof that specifically binds to a polypeptide corresponding to the mid-portion or C terminus of a hepcidin protein, and quantifying the hepcidin level using an assay based on binding of the antibody and the polypeptide; wherein the non-physiological level of hepcidin is indicative of the disease condition. The present invention also concerns diagnostic methods and kits for applications in genetic technological approaches, such as for overexpressing or downregulating hepcidin. The present invention further concerns therapeutic treatment of certain diseases by treatment of subjects with hepcidin and agonists or antagonists of hepcidin. | 11-24-2011 |
20120003696 | DIAGNOSTIC METHODS FOR DISEASES BY SCREENING FOR HEPCIDIN IN HUMAN OR ANIMAL TISSUES, BLOOD OR BODY FLUIDS, MONOCLONAL ANTIBODIES SPECIFIC TO HUMAN HEPCIDIN AND ASSOCIATED USES THEREFOR - The present invention concerns antibodies specific for the C-terminus of human hepcidin, and related methods and kits for diagnosing and/or treating a disease condition characterized by non-physiological levels of hepcidin protein, including prohepcidin and fragments thereof, comprising obtaining a tissue or fluid sample from a subject; contacting the sample with an antibody or fragment thereof that specifically binds to a polypeptide corresponding to the amino acid sequence between and including amino acids 60 and 84, or, in another embodiment, amino acids 74 and 81, as aligned with the human pre-pro-hepcidin precursor protein, and quantifying the pro-hepcidin and/or mature hepcidin level using an assay based on binding of the antibody and the polypeptide; wherein the non-physiological level of prohepcidin/mature hepcidin is indicative of the disease condition. The present invention also concerns diagnostic methods and kits for applications in genetic technological approaches, such as for overexpressing or downregulating hepcidin. | 01-05-2012 |
20120252109 | REAGENT CARTRIDGE FOR AN ASSEMBLY FOR SELECTIVELY PERFORMING A CLINCIAL CHEMICAL TEST OR AN ELISA TEST, USE OF SAID REAGENT CARTRIDGE AND ASSEMBLY - The invention relates to a reagent cartridge | 10-04-2012 |
20130183694 | Method For Analyzing A Sample - The invention relates to a method of analysing a sample, comprising the analysis of clinical-chemical parameters and the analysis of immunodiagnostic parameters in a fully automatic analysis apparatus, wherein the analysis apparatus comprises a pipetting apparatus, at least one holder for a reagent cartridge containing the components necessary for carrying out the analysis, a holding apparatus for a measurement cell, at least one measurement cell, with each reagent cartridge being associated with a measurement cell, a holding apparatus for a sample container containing sample, and a photometric or spectrometric measurement device. On the basis of a sample it is possible here for a plurality of different clinical-chemical and/or immunodiagnostic parameters to be determined, to which end a dedicated reagent cartridge is inserted into a holding apparatus of the analysis apparatus for each clinical-chemical or immunodiagnostic parameter to be determined. | 07-18-2013 |
20140377785 | ASSEMBLY FOR SELECTIVELY PERFORMING A CLINICAL CHEMISTRY TEST OR AN ELISA ASSAY, USE OF SAID REAGENT CARTRIDGE AND ASSEMBLY - An assembly for selectively performing a clinical chemical test or an ELISA assay including a reagent cartridge with a housing | 12-25-2014 |
Patent application number | Description | Published |
20110242106 | Generalized scatter plots - Color cell-based data placement systems, methods, and computer-readable storage media that visualize large amounts of multidimensional data on an output by rearranging data objects to variably grant more output space to areas with high data density and less output space to areas with low data density, and to variably rearrange overlapping data objects based on a number of data objects already placed at a preferred cell position for the data object. | 10-06-2011 |
20130030759 | SMOOTHING A TIME SERIES DATA SET WHILE PRESERVING PEAK AND/OR TROUGH DATA POINTS - Implementations disclosed herein relate to smoothing a time series data set while preserving at least one of peak or trough data points. In one embodiment, a processor recursively identifies at least one of a peak or trough point outside of a threshold distance from a connecting line connecting a beginning and ending point within the time series data set. | 01-31-2013 |
20130088493 | PROVIDING AN ELLIPSOID HAVING A CHARACTERISTIC BASED ON LOCAL CORRELATION OF ATTRIBUTES - Data records are grouped into clusters according to attributes of the data records to be correlated. At least two of the clusters that satisfy a proximity criterion are merged. At least one ellipsoid is created for presentation in a scatter plot visualization based on the grouping and merging, the ellipsoid including pixels representing multiple corresponding data records. The ellipsoid has a characteristic based on a corresponding local correlation of the attributes of the data records represented by the ellipsoid. The characteristic of the ellipsoid is adjusted based on a direction of the local correlation. | 04-11-2013 |
20130103616 | Computing Predicted Data According to Weighted Peak Preservation and Time Distance Biasing - A value corresponding to an adjustable control element is received. Predicted data is computed from seasonal data, where the computing is according to applying preservation of peaks in the seasonal data and applying time distance biasing in which more recent data points in the seasonal data are weighted higher than less recent data points. Relative weighting of the peak preservation and the time distance biasing is based on the received value corresponding to the adjustable control element. | 04-25-2013 |
20130194272 | PLACING PIXELS ACCORDING TO ATTRIBUTE VALUES IN POSITIONS IN A GRAPHICAL VISUALIZATION THAT CORRESPOND TO GEOGRAPHIC LOCATIONS - Data records representing user feedback are received, where the data records are associated with geometric coordinates. Pixels representing the corresponding data records are placed in positions in a graphical visualization according to the geometric coordinates of the data records, where the positions correspond to geographic locations. A subset of the pixels sharing a particular set of geometric coordinates is placed in a subregion of nearby positions in the graphical representation, where the pixels in the subset are placed in an order in the subregion according to values of an attribute of the data records corresponding to the pixels in the subset. | 08-01-2013 |
20130257903 | OVERLAYING TRANSPARENCY IMAGES INCLUDING PIXELS CORRESPONDING TO DIFFERENT HEIRARCHICAL LEVELS OVER A GEOGRAPHIC MAP - Data records contain corresponding values of an attribute and are associated with location information. Hierarchical levels of transparency images are generated, where each of the transparency images includes corresponding pixels that represent the respective data records, and where the transparency images at different ones of the hierarchical levels correspond to different zoom levels of a geographic map. At least one of the transparency images at a dynamically-selected one of the hierarchical levels is overlaid over the geographic map according to which of the zoom levels is selected by a user in zooming of the geographic map, where the at least one transparency image is automatically selected without user input. | 10-03-2013 |
20130278623 | PROVIDING A CORRELATION RING FOR INDICATING CORRELATION BETWEEN ATTRIBUTES - Pixels representing attributes of data records are into discrete rings of a graphical visualization, where the discrete rings correspond to respective ones of the attributes, and where the pixels are arranged in each of the discrete rings according to time intervals of the data records. A correlation ring is provided in the graphical visualization in addition to the discrete rings, where the correlation ring has visual indicators for indicating degrees of correlation between at least two of the attributes. | 10-24-2013 |
20140365149 | Visual Analytics of Spatial Time Series Data Using a Pixel Calendar Tree - Example embodiments relate to providing visual analytics of spatial time series data. In example embodiments, sensors may be located at regions within a building for collecting sensor data at regular time intervals. A sensor hierarchy can be generated including sensor nodes that are hierarchically arranged according to a physical infrastructure of the building, where each of the sensor nodes corresponds to a sensor. Sensor data can be obtained from the sensors, and a pixel calendar tree can be generated based on the sensor data and the sensor hierarchy, where the pixel calendar tree is recursively subdivided into tree portions according to a proportion of the sensor data attributable to each of the sensors. The pixel calendar tree can be displayed, where each of the tree portions includes time series sensor data of a corresponding region that is generated based on the sensor data. | 12-11-2014 |
20150035833 | Visual Analytics of Temporal-spatial Relationships Using a Hierarchical Pixel Calendar Tree - Example embodiments relate to providing visual analytics of temporal-spatial relationships. In example embodiments, power meters may be located at regions within a building for collecting power consumption data at regular intervals. The power consumption data can be recursively processed to generate a pixel calendar tree by using a power meter hierarchy to subdivide the pixel calendar tree into tree portions according to a proportion of the power consumption data attributed to each of power meter nodes, where the tree portions are arranged in the pixel calendar tree according to an importance of the proportion; generating pixel cells in the pixel calendar tree that each represent a day in the power consumption data; and generating cell borders that each surround one of the pixel cells. At this stage, a pixel calendar display of a physical infrastructure of the building that includes the pixel cells and the cell borders can be generated. | 02-05-2015 |
Patent application number | Description | Published |
20110279469 | Performing time slice-based visual prediction - To perform time slice-based visual prediction, a weighted moving aggregate of data values in a data set is calculated over previous time slices to predict data values based on interactive user input. A visual accuracy indicator is generated for display to indicate a quality of prediction of data values at different times. A visualization presents data values from the data set and the predicted data values, where the data values from the data set and the predicted data values are represented as corresponding cells. | 11-17-2011 |
20120089941 | Visualizing motifs with visual structures - Visual structures are produced to represent corresponding motifs, where the motifs correspond to repeating patterns in an input data set, where sizes of the visual structures are based on values of a characteristic associated with the motifs, and where a first of the motifs is nested within a second of the motifs to represent a hierarchical relationship of the patterns represented by the first and second motifs. The visual structures of corresponding motifs are presented for display in a visualization screen, where the visualization screen depicts the data in the input data set with the visual structures overlapping parts of depicted data. Interactive input is received specifying modification of a region containing motifs, wherein the specified modification includes interactive distortion of the visual structures in the region to change a size of the visual structures in the region. | 04-12-2012 |
20130088493 | PROVIDING AN ELLIPSOID HAVING A CHARACTERISTIC BASED ON LOCAL CORRELATION OF ATTRIBUTES - Data records are grouped into clusters according to attributes of the data records to be correlated. At least two of the clusters that satisfy a proximity criterion are merged. At least one ellipsoid is created for presentation in a scatter plot visualization based on the grouping and merging, the ellipsoid including pixels representing multiple corresponding data records. The ellipsoid has a characteristic based on a corresponding local correlation of the attributes of the data records represented by the ellipsoid. The characteristic of the ellipsoid is adjusted based on a direction of the local correlation. | 04-11-2013 |
20130103616 | Computing Predicted Data According to Weighted Peak Preservation and Time Distance Biasing - A value corresponding to an adjustable control element is received. Predicted data is computed from seasonal data, where the computing is according to applying preservation of peaks in the seasonal data and applying time distance biasing in which more recent data points in the seasonal data are weighted higher than less recent data points. Relative weighting of the peak preservation and the time distance biasing is based on the received value corresponding to the adjustable control element. | 04-25-2013 |
20130194272 | PLACING PIXELS ACCORDING TO ATTRIBUTE VALUES IN POSITIONS IN A GRAPHICAL VISUALIZATION THAT CORRESPOND TO GEOGRAPHIC LOCATIONS - Data records representing user feedback are received, where the data records are associated with geometric coordinates. Pixels representing the corresponding data records are placed in positions in a graphical visualization according to the geometric coordinates of the data records, where the positions correspond to geographic locations. A subset of the pixels sharing a particular set of geometric coordinates is placed in a subregion of nearby positions in the graphical representation, where the pixels in the subset are placed in an order in the subregion according to values of an attribute of the data records corresponding to the pixels in the subset. | 08-01-2013 |
20130257903 | OVERLAYING TRANSPARENCY IMAGES INCLUDING PIXELS CORRESPONDING TO DIFFERENT HEIRARCHICAL LEVELS OVER A GEOGRAPHIC MAP - Data records contain corresponding values of an attribute and are associated with location information. Hierarchical levels of transparency images are generated, where each of the transparency images includes corresponding pixels that represent the respective data records, and where the transparency images at different ones of the hierarchical levels correspond to different zoom levels of a geographic map. At least one of the transparency images at a dynamically-selected one of the hierarchical levels is overlaid over the geographic map according to which of the zoom levels is selected by a user in zooming of the geographic map, where the at least one transparency image is automatically selected without user input. | 10-03-2013 |
20130278623 | PROVIDING A CORRELATION RING FOR INDICATING CORRELATION BETWEEN ATTRIBUTES - Pixels representing attributes of data records are into discrete rings of a graphical visualization, where the discrete rings correspond to respective ones of the attributes, and where the pixels are arranged in each of the discrete rings according to time intervals of the data records. A correlation ring is provided in the graphical visualization in addition to the discrete rings, where the correlation ring has visual indicators for indicating degrees of correlation between at least two of the attributes. | 10-24-2013 |