Jacobs, NC
Barry A. Jacobs, Matthews, NC US
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20090012192 | Low Scorching Flame Retardants for Colored Polyurethane Foams - Flame retarded, colored polyurethane foam compositions having reduced discoloration, said foam compositions comprising a foam, which is the reaction product of a polyol and an isocyanate, a colorant, a flame retardant of the type that normally causes scorch and a benzofuranone derivative, as an anti-scorch stabilizer. | 01-08-2009 |
Cassandra Jacobs, Durham, NC US
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20120302626 | MICRORNA AND USE THEREOF IN IDENTIFICATION OF B CELL MALIGNANCIES - Disclosed are nucleic acid sequences, including microRNA sequences and cDNA sequences, as well as vectors, DNA libraries, microarrays, and recombinant cells comprising the nucleic acid sequences described herein. Methods of determining the B cell stage from which a B cell malignancy is derived. Methods of identifying B cell malignancies are also provided. Methods of diagnosing B cell malignancies are provided. Such methods comprise, in certain embodiments, detecting one or more microRNAs or cDNAs as disclosed herein. | 11-29-2012 |
Danny O. Jacobs, Durham, NC US
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20120315654 | COMPOSITIONS AND METHODS FOR DETECTING CARDIOTOXICITY - The present disclosure provides methods and compositions for detecting the presence and activity of creatine transporter proteins (CrT) in biological samples comprising screening the samples for CrT using antibodies that bind to the CrT. The methods are useful to detect the onset of cardiotoxicity in subjects undergoing treatment with anthrocyclines or those susceptible to heart-related conditions. The methods and compositions described herein in can be practiced with diagnostic kits. | 12-13-2012 |
Joseph M. Jacobs, Mebane, NC US
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20080301347 | USB2.0 BI DIRECTIONAL AMPLIFIER - A system for allowing a designer to implement Universal Serial Bus (USB) 2.0 in topologies not anticipated by a USB 2.0 specification and with reduced channel losses, the system comprising: a bus channel having a plurality of electrical elements; and a boost circuit connected at a predetermined location on the bus channel; a plurality of USB signals transmitted through the system; wherein edges of the plurality of USB signals are boosted without impacting the bi-directional nature of the bus channel. | 12-04-2008 |
Kenneth M. Jacobs, Greenville, NC US
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20110090500 | FLOW CYTOMETER APPARATUS FOR THREE DIMENSIONAL DIFRACTION IMAGING AND RELATED METHODS - A flow cytometer assembly includes a fluid controller configured to form a hydrodynamically focused flow stream including an outer sheath fluid and an inner core fluid. A coherent light source is configured to illuminate a particle in the inner core fluid. A detector is configured to detect a spatially coherent distribution of elastically scattered light from the particle excited by the coherent light source. An analyzing module configured to extract a three-dimensional morphology parameter of the particle from a spatially coherent distribution of the elastically scattered light. | 04-21-2011 |
Marco C. Jacobs, Durham, NC US
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20090063724 | System core for transferring data between an external device and memory - Details of a highly cost effective and efficient implementation of a manifold array (ManArray) architecture and instruction syntax for use therewith are described herein. Various aspects of this approach include the regularity of the syntax, the relative ease with which the instruction set can be represented in database form, the ready ability with which tools can be created, the ready generation of self-checking codes and parameterized test cases. Parameterizations can be fairly easily mapped and system maintenance is significantly simplified. | 03-05-2009 |
20110219210 | System Core for Transferring Data Between an External Device and Memory - Details of a highly cost effective and efficient implementation of a manifold array (ManArray) architecture and instruction syntax for use therewith are described herein. Various aspects of this approach include the regularity of the syntax, the relative ease with which the instruction set can be represented in database form, the ready ability with which tools can be created, the ready generation of self-checking codes and parameterized test cases. Parameterizations can be fairly easily mapped and system maintenance is significantly simplified. | 09-08-2011 |
Mark E. Jacobs, Roxboro, NC US
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20120152187 | PUMP ACTUATOR ANTI-ROTATION DEVICE - A tappet having a contiguous body, an outer wall and transverse web. The outer wall defines a cylindrically-shaped outer surface and a recess. The recess is disposed within cylindrical surface of the body. An alignment member is press-fit between two staked ends of the recess, which engage opposite sides of the alignment member. The alignment member extends outwardly from the cylindrically-shaped surface. A roller is mounted to the contiguous body at the cam contacting end of the tappet. | 06-21-2012 |
Michael Jacobs, Harrisburg, NC US
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20080265014 | Credit Relationship Management - Systems and methods are disclosed for managing a credit relationship and determining whether to extend credit to a customer. A plurality of user devices may be linked and provided shared access to a customer account over a computer network to assist in streamlining an underwriting decision in a line of business. A customer account may be approved by entering customer data and credit data into a data file, performing a credit decision on the data file, and approving the data file. The approval process may comprise a plurality of modules including a customer module, a credit module, a review module, an exposure module, a relationship module, an approval module, and optionally a tracking module and/or a maintenance module. Further, users or computing devices may be permitted to enter data, alter data, view data, or some combination of viewing, entering, and altering data within one or more of the modules. | 10-30-2008 |
Randall Howard Jacobs, Wilmington, NC US
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20100091928 | PROTECTION SYSTEMS FOR NUCLEAR BOILING WATER REACTORS - A protection system for a nuclear boiling water reactor may include a device configured to monitor reactor power; a device configured to monitor reactor pressure; a device configured to determine a power-dependent high reactor pressure setpoint, based on the monitored reactor power; and a device configured to initiate a protection system action when the monitored reactor pressure is greater than the power-dependent high reactor pressure setpoint. The power-dependent high reactor pressure setpoint that corresponds to at least one value of percent power in an operating domain of the reactor may be less than the power-dependent high reactor pressure setpoint that corresponds to 100% reactor power. | 04-15-2010 |
Robert Jacobs, Wake Forest, NC US
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20100160627 | NOVEL LACTAMS AND USES THEREOF - Compounds having the formula (I) | 06-24-2010 |
20110190235 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS - This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent. | 08-04-2011 |
20110207702 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS - This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent. | 08-25-2011 |
Robert Jacobs, Research Triangle Park, NC US
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20080311609 | Novel Molecular Probes - The present invention relates to novel molecular probes having the formula (I) (I) useful for the characterization, detection, localization and isolation of the γ-secretase enzyme. | 12-18-2008 |
Robert Jacobs, Durham, NC US
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20090170851 | Chroman Compounds - Compounds according to Formula (I): | 07-02-2009 |
Robert T. Jacobs, Durham, NC US
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20090291917 | Boron-Containing Small Molecules as Anti-Inflammatory Agents - Compounds and methods of treating anti-inflammatory conditions are disclosed. | 11-26-2009 |
Robert T. Jacobs, Wake Forest, NC US
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20120214765 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS - Compounds and methods of treating anti-inflammatory conditions are disclosed. | 08-23-2012 |
20130231304 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENT - This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent. | 09-05-2013 |
Robert Toms Jacobs, Wake Forest, NC US
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20080312272 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF - The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I): | 12-18-2008 |
20100125089 | ENANTIOMERICALLY ENRICHED ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF - The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives substantially enriched in an enantiomer of formula (I): | 05-20-2010 |
20120149750 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF - The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I): | 06-14-2012 |
20140080862 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF - The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I): | 03-20-2014 |
Scott L. Jacobs, Pittsboro, NC US
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20120097971 | CONTIGUOUS AND VIRTUALLY CONTIGUOUS AREA EXPANSION OF SEMICONDUCTOR SUBSTRATES - Substrates are processed, with a high degree of topography, to produce a variety of semiconductors or other devices and are then stretched out, substantially flat, to achieve a significant increase in surface area. Devices made from a contiguous structure of a single, active crystalline material or from non-contiguous structures of multiple materials, such as a combination of dielectrics, thin film metals and active crystalline semiconductors, are fabricated by utilizing anisotropically etched, high aspect ratio configurations of the active material. The structure is then stretched out to achieve a significant increase in surface area, thereby enabling a substantial reduction in the cost of the substrate materials per unit area in the final product. | 04-26-2012 |