Patent application number | Description | Published |
20100036997 | MULTIPLE DATA CHANNEL MEMORY MODULE ARCHITECTURE - The present invention is directed generally to systems and methods which provide a memory module having multiple data channels that are independently accessible (i.e., a multi-data channel memory module). According to one embodiment, the multi-data channel memory module enables a plurality of independent sub-cache-block accesses to be serviced simultaneously. In addition, the memory architecture also supports cache-block accesses. For instance, multiple ones of the data channels may be employed for servicing a cache-block access. In one embodiment a DIMM architecture that comprises multiple data channels is provided. Each data channel supports a sub-cache-block access, and multiple ones of the data channels may be used for supporting a cache-block access. The plurality of data channels to a given DIMM may be used simultaneously to support different, independent memory access operations. | 02-11-2010 |
20100037024 | MEMORY INTERLEAVE FOR HETEROGENEOUS COMPUTING - A memory interleave system for providing memory interleave for a heterogeneous computing system is provided. The memory interleave system effectively interleaves memory that is accessed by heterogeneous compute elements in different ways, such as via cache-block accesses by certain compute elements and via non-cache-block accesses by certain other compute elements. The heterogeneous computing system may comprise one or more cache-block oriented compute elements and one or more non-cache-block oriented compute elements that share access to a common main memory. The cache-block oriented compute elements access the memory via cache-block accesses (e.g., 64 bytes, per access), while the non-cache-block oriented compute elements access memory via sub-cache-block accesses (e.g., 8 bytes, per access). A memory interleave system is provided to optimize the interleaving across the system's memory banks to minimize hot spots resulting from the cache-block oriented and non-cache-block oriented accesses of the heterogeneous computing system. | 02-11-2010 |
20120079177 | MEMORY INTERLEAVE FOR HETEROGENEOUS COMPUTING - A memory interleave system for providing memory interleave for a heterogeneous computing system is provided. The memory interleave system effectively interleaves memory that is accessed by heterogeneous compute elements in different ways, such as via cache-block accesses by certain compute elements and via non-cache-block accesses by certain other compute elements. The heterogeneous computing system may comprise one or more cache-block oriented compute elements and one or more non-cache-block oriented compute elements that share access to a common main memory. The cache-block oriented compute elements access the memory via cache-block accesses (e.g., 64 bytes, per access), while the non-cache-block oriented compute elements access memory via sub-cache-block accesses (e.g., 8 bytes, per access). A memory interleave system is provided to optimize the interleaving across the system's memory banks to minimize hot spots resulting from the cache-block oriented and non-cache-block oriented accesses of the heterogeneous computing system. | 03-29-2012 |
20150206561 | MULTIPLE DATA CHANNEL MEMORY MODULE ARCHITECTURE - The present invention is directed generally to systems and methods which provide a memory module having multiple data channels that are independently accessible (i.e., a multi-data channel memory module). According to one embodiment, the multi-data channel memory module enables a plurality of independent sub-cache-block accesses to be serviced simultaneously. In addition, the memory architecture also supports cache-block accesses. For instance, multiple ones of the data channels may be employed for servicing a cache-block access. In one embodiment a DIMM architecture that comprises multiple data channels is provided. Each data channel supports a sub-cache-block access, and multiple ones of the data channels may be used for supporting a cache-block access. The plurality of data channels to a given DIMM may be used simultaneously to support different, independent memory access operations. | 07-23-2015 |
Patent application number | Description | Published |
20080292738 | MOTOR DRIVEN MOLD - A mold includes a controller and core actuators that may independently drive a plurality of mold cores positioned with the mold. Sensors may be included whereby the mold cores are positioned in the mold core responsive to the sensor feedback. The core actuators may be servomotors and may further include motor controllers, one for each servomotor, for use in actuating the mold cores. | 11-27-2008 |
20080302697 | DUAL PACK CONTAINER - A container for packaging associated articles includes coupling members fashioned on one or more sides of the container for interconnecting a plurality of containers together. The coupling members may be integrally fashioned with the containers and may comprise raised ribs and recessed channels for press fitting the adjacently placed containers together. | 12-11-2008 |
20090043257 | ADAPTER FOR POWER INJECTORS - A syringe adapter includes an adapter body having a first connecting portion that may be received into a power injector unit used to deliver contrast media. The adapter also includes a second connecting portion configured to receive the rearward end of an associated syringe. The adapter includes means for encoding information about the associated syringe that may be communicated to the power injector unit through one or more sensors. The means for encoding information may include a mechanism that moves linearly laterally back and forth to activate an actuator used to convey the encoded information. In particular, the action of installing the adapter may be decoupled from the action of encoding information. | 02-12-2009 |
20100094260 | LUER LOCK ADAPTER - An adapter for a medical receptacle having a skirt with an outside diameter and a threaded inside diameter, and a tapered post within the skirt, the adapter includes a proximal end portion having a threaded surface including at least one thread configured to threadingly engage the threaded inside diameter of the skirt, a distal end portion having a surface portion and a cylindrical recess, a conduit positioned between the tapered recess and the cylindrical recess such that the conduit is in fluid communication with both the tapered recess and the cylindrical recess; and a longitudinal axis. The proximal end portion includes a tapered recess defined by a wall, a chamfer, and a seat and the surface portion includes a means for gripping, which in one embodiment may be at least two wings. | 04-15-2010 |
20100137714 | ADAPTER FOR POWER INJECTIONS - A syringe adapter includes an adapter body having a first connecting portion that may be received into a power injector unit used to deliver contrast media. The adapter also includes a second connecting portion configured to receive the rearward end of an associated syringe. The adapter includes means for encoding information about the associated syringe that may be communicated to the power injector unit through one or more sensors. The means for encoding information may include a mechanism that moves linearly laterally back and forth to activate an actuator used to convey the encoded information. In particular, the action of installing the adapter may be decoupled from the action of encoding information. | 06-03-2010 |
20110097433 | MOTOR DRIVEN MOLD - A mold includes a controller and core actuators that may independently drive a plurality of mold cores positioned with the mold. Sensors may be included whereby the mold cores are positioned in the mold core responsive to the sensor feedback. The core actuators may be servomotors and may further include motor controllers, one for each servomotor, for use in actuating the mold cores. | 04-28-2011 |
20110283510 | METHOD OF LOCKING A SYRINGE TO AN INJECTOR - A syringe adapter assembly | 11-24-2011 |
20130086773 | SURGICAL INSTRUMENT PACKAGING CLIP SYSTEM - A clip used in connection with a tube having sections arranged to form a coil, the clip comprising a first section and a second section joined at one end by a hinge and at an opposite end by a clasp to define a channel between the first and second sections, and a first pair of ridges where each ridge is an opposing relationship with the other and extends inwardly from a respective first and second section partially into the channel defining a gap therebetween and dividing the channel into channel sections, whereby the sections of the tube are received in the channel sections and extend toward contact with each other in the gap formed between the ridges. | 04-11-2013 |
20130158520 | LUER LOCK ADAPTER - An adapter for a medical receptacle having an internally threaded skirt with an outside diameter and an inside diameter, and a post within the skirt, includes a proximal end portion having a threaded surface including at least one thread configured to threadingly engage a threaded interior of a skirt of a medical receptacle, and a distal end portion having a surface portion and a generally cylindrical recess. The proximal end portion includes a tapered recess defined by a wall, a chamfer, and a seat and the surface portion includes a gripping mechanism. A conduit is positioned between the tapered recess and the generally cylindrical recess such that the conduit is in fluid communication with both the recess and the generally cylindrical recess. | 06-20-2013 |
20130190731 | GUIDEWIRE POSITIONING TOOL - A guidewire positioning tool includes a sheath having a body bore extending axially through a length of the sheath with a radially extending body slot configured to receive a guidewire. A collet portion extends laterally from the sheath and has collet arms and interstitial spaces with a collet bore extending therethrough. The collet bore has a collet slot extending radially from the collet bore configured to receive a guidewire. The collet arms have threads located on the exterior of the collet arms. A clamp nut is positioned over the collet portion and configured to threadably engage the threads. A retainer is rotatably attached to an end of the sheath opposite from the collet portion. The retainer has a retainer bore extending axially therethrough. The retainer has a retainer slot extending radially from the retainer bore configured to receive a guidewire. | 07-25-2013 |
20140237798 | GUIDEWIRE INSERTION TOOL - A guidewire insertion tool includes a sidewall defining a passageway having a first open end and a second open end and a neck therebetween. The passageway tapers from the first and second open ends to the neck. The sidewall has a slit extending longitudinally along the sidewall. A tab is adjacent one of the first or second open ends for removing the tool from a guidewire through the slit. | 08-28-2014 |
20150209507 | SYRINGE - A syringe for a power injector includes a barrel having a distal end and a proximal end. The barrel defines an interior volume therebetween the distal and proximal ends. A circumferential flange extends about the proximal end. A delivery tip extends from the distal end. The barrel includes a thick wall section adjacent the distal end and a thin wall section adjacent the proximate end. | 07-30-2015 |
Patent application number | Description | Published |
20090248432 | HEURISTIC MATCHING METHOD FOR USE IN FINANCIAL SYSTEMS - A heuristic method is described for use with a financial system, wherein the method receives a newly added research item, extracts a text-based index from the newly added research item, applying a plurality of heuristics to said extracted text-based index, matches results of heuristics application with each of the following entity types: companies contacts, industries, themes, and ideas, and, upon detecting a match, creating a bidirectional link between the newly added research item and the matching entity type. The results of the detected match is then stored in a database. The heuristics comprises any of, or a combination of, the following: heuristics to match the text-based index to a subset of existing research items that have been pre-selected, heuristics to match the text-based index to a company's ticker symbol, (3) heuristics to maintain a problem ticker list that is used to negate matches for tickers in said text-based index that can also represent common abbreviations, (4) heuristics to convert said extracted text-based index to a base or root form, and (5) heuristics to remove short, high frequency, common, and low relevance words from said extracted text-based index; | 10-01-2009 |
20090248433 | METHOD FOR AUTOMATICALLY LINKING A DATA ELEMENT TO EXISTING RESEARCH - Business research items are maintained for a subscriber, wherein the business items are any of the following: company information, contact information, ideas, themes, or notes. When the user creates a new item for business research, the input is parsed to match the parsed user input to indexed research to identify a matching entry (or entries), wherein a link is automatically suggested between the matching entry (or entries) and the new item to be created. Upon receiving an acknowledgement from the user accepting the suggestion, the suggested link is stored in permanent memory. | 10-01-2009 |
Patent application number | Description | Published |
20080234619 | Portable Hyperthermia Apparatus - An apparatus for implementing hyperthermia may include a reservoir cartridge having an inlet and an outlet, a disposable outflow tube having a reservoir cartridge end connected to the reservoir cartridge at the outlet and an outflow catheter end connected to an outflow catheter, a disposable inflow tube having a reservoir cartridge end connected to the reservoir cartridge at the inlet and an inflow catheter end connected to an inflow catheter, a pump connected to the outflow tube, an integrated computer in communication with at least one disposable temperature sensor and at least one pressure sensor, a thermoelectric heater, proximate to the reservoir cartridge and a housing that contains the reservoir cartridge, the heater and the integrated computer. | 09-25-2008 |
20120105136 | FUSE LINK SYSTEM FOR DISPOSABLE COMPONENT - A fuse system for use with a disposable component of a device may include a disposable component having at least a first lockout circuit and a second lockout circuit. The first lockout circuit may include a first fuse link, and the second lockout circuit may include a second fuse link. The fuse system may include a computing device in communication with the first lockout circuit and the second lockout circuit, and a computer-readable storage medium in communication with the computing device. The computer-readable storage medium may include one or more programming instructions for deactivating the first fuse link at a first time, and deactivating the second fuse link at a second time. | 05-03-2012 |
20120106016 | Fuse Link System For A Hyperthermia Apparatus - A fuse system for a hyperthermia apparatus may include a disposable reservoir cartridge configured to be used with a hyperthermia apparatus. The disposable reservoir cartridge may include at least a first lockout circuit and a second lockout circuit. The first lockout circuit may include a first fuse link, and the second lockout circuit may include a second fuse link. The fuse system may include a computing device in communication with the first lockout circuit and the second lockout circuit, and a computer-readable storage medium in communication with the computing device. The computer-readable storage medium may include one or more programming instructions for deactivating the first fuse link at a first time, and deactivating the second fuse link at a second time. | 05-03-2012 |
20120109267 | HEATING SYSTEM FOR A HYPERTHERMIA APPARATUS - A heating system for a hyperthermia apparatus may include a heater having a plurality of independently controllable heater elements located on one or more surfaces of the heater, and a temperature sensor associated with one or more of the heater elements. Each of the surfaces may be proximate to a reservoir cartridge. The heating system may include a computing device in communication with the temperature sensor. The computing device may be configured to adjust an amount of electrical current to the one or more heater elements associated with the temperature sensor based on a temperature reading received from the temperature sensor. | 05-03-2012 |
Patent application number | Description | Published |
20140025278 | STOCHASTIC PRE-IGNITION MITIGATION SYSTEM - A stochastic pre-ignition (SPI) mitigation system includes a detection module, an engine load module, and an evaluation module. The detection module generates a pre-ignition determination signal indicating detection of a SPI event in a cylinder of an engine. The engine load module determines load on the engine and generates an engine load signal based on the load. The evaluation module determines whether to operate in a single-pulse mode or a multi-pulse mode and generating a mode signal to operate in a selected one of the single-pulse mode and the multi-pulse mode based on the pre-ignition determination signal and the engine load signal. The single pulse mode includes injecting a single pulse of fuel into the cylinder during a first per combustion cycle of the cylinder. The multi-pulse mode includes injecting multiple pulses of fuel into the cylinder during a second combustion cycle of the cylinder. | 01-23-2014 |
20140163844 | STOCHASTIC PRE-IGNITION PREDICTION AND MITIGATION SYSTEMS AND METHODS - An engine control system for a vehicle includes a timer module, a stochastic pre-ignition (SPI) mitigation module, and a boost control module. The timer module tracks a period of operation of an engine where vacuum within an intake manifold is less than a first predetermined vacuum. The SPI mitigation module generates an SPI signal when the period is greater than a predetermined period and the vacuum is less than a second predetermined vacuum. The second predetermined vacuum is less than the first predetermined vacuum. The boost control module reduces output of a turbocharger in response to the generation of the SPI signal. | 06-12-2014 |
20140222315 | SYSTEM AND METHOD FOR PREVENTING STOCHASTIC PRE-IGNITION - A system according to the principles of the present disclosure includes a stochastic pre-ignition module and a fuel control module. The stochastic pre-ignition module determines whether operating conditions of an engine satisfy predetermined criteria associated with stochastic pre-ignition. The fuel control module enriches an air/fuel ratio of the engine when the engine operating conditions satisfy the predetermined criteria. | 08-07-2014 |
20140238120 | SYSTEM AND METHOD FOR DETECTING STOCHASTIC PRE-IGNITION - A system according to the principles of the present disclosure includes a vibration intensity module and a stochastic pre-ignition (SPI) detection module. The vibration intensity module determines a vibration intensity of an engine over a first engine cycle and a second engine cycle. The first engine cycle and the second engine cycle each correspond to a predetermined amount of crankshaft rotation. The SPI detection module selectively detects stochastic pre-ignition when the vibration intensity of the first engine cycle is less than a first threshold and the vibration intensity of the second engine cycle is greater than a second threshold. | 08-28-2014 |
20140343812 | ENGINE STARTUP CONTROL SYSTEMS AND METHODS - An engine control system of a vehicle includes a starter control module and an abort module. When a clutch pedal is depressed and a user activates an ignition system, the starter control module engages a starter motor with an engine and applies current to the starter motor. The abort module selectively generates an abort signal when the clutch pedal is released. The starter control module disengages the starter motor and disables current flow to the starter motor when the abort signal is generated. | 11-20-2014 |
Patent application number | Description | Published |
20110085168 | Luminescence Reference Standards - The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis. | 04-14-2011 |
20130224877 | LUMINESCENCE REFERENCE STANDARDS - The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis. | 08-29-2013 |
20140284496 | LUMINESCENCE REFERENCE STANDARDS - The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis. | 09-25-2014 |
20150015876 | Luminescence Reference Standards - The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis. | 01-15-2015 |
20150111200 | Luminescence Reference Standards - The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis. | 04-23-2015 |
Patent application number | Description | Published |
20080227804 | Polymorphic Forms of Naltrexone - This invention relates to the discovery of novel polymorphic forms of naltrexone, including solvates, hydrates, anhydrous and other crystalline forms and combinations thereof. These novel forms of naltrexone impart advantages in pharmaceutical formulations incorporating them, including sustained release, or long acting, formulations. | 09-18-2008 |
20080233199 | Coacervation Process - Methods of forming compositions for the sustained release of water soluble active agents, including biologically active polypeptides and products produced by the process are described. Improved product characteristics and ease of scale-up can be achieved using a novel coacervation process wherein at least one coacervation agent is added to the mixture comprising the active agent and the polymer in at least two distinct stages. | 09-25-2008 |
20090194894 | Residual solvent extraction method and microparticles produced thereby - Methods for preparing microparticles having reduced residual solvent levels. Microparticles are contacted with a non-aqueous washing system to reduce the level of residual solvent in the microparticles. Preferred non-aqueous washing systems include 100% ethanol and a blend of ethanol and heptane. A solvent blend of a hardening solvent and a washing solvent can be used to harden and wash microparticles in a single step, thereby eliminating the need for a post-hardening wash step. | 08-06-2009 |
20100303900 | PREPARATION OF INJECTABLE SUSPENSIONS HAVING IMPROVED INJECTABILITY - Injectable compositions having improved injectability. The injectable compositions include microparticles suspended in an aqueous injection vehicle having a viscosity of at least 20 cp at 20° C. The increased viscosity of the injection vehicle that constitutes the fluid phase of the suspension significantly reduces in vivo injectability failures. The injectable compositions can be made by mixing dry microparticles with an aqueous injection vehicle to form a suspension, and then mixing the suspension with a viscosity enhancing agent to increase the viscosity of the fluid phase of the suspension to the desired level for improved injectability. | 12-02-2010 |
20110086104 | RESIDUAL SOLVENT EXTRACTION METHOD AND MICROPARTICLES PRODUCED THEREBY - Methods for preparing microparticles having reduced residual solvent levels. Microparticles are contacted with a non-aqueous washing system to reduce the level of residual solvent in the microparticles. Preferred non-aqueous washing systems include 100% ethanol and a blend of ethanol and heptane. A solvent blend of a hardening solvent and a washing solvent can be used to harden and wash microparticles in a single step, thereby eliminating the need for a post-hardening wash step. | 04-14-2011 |
20110237748 | METHODS AND SYSTEMS FOR GENERATING NANOPARTICLES - In one aspect, the present invention provides a process for forming polymeric nanoparticles, which comprises using a static mixer to create a mixed flowing stream of an anti-solvent, e.g., by introducing a liquid anti-solvent into a static mixer, and introducing a polymer solution into the mixed flowing anti-solvent stream such that controlled precipitation of polymeric nanoparticles occurs. The nanoparticles can then be separated from the anti-solvent stream. | 09-29-2011 |
20120196990 | METHOD FOR FABRICATING NANOPARTICLES - Systems and methods are provided for filtering a fluid containing nanoparticles. The systems and methods generally include introducing a stream of the nanoparticle-containing fluid into a holding vessel, and extracting at least a part of a nanoparticle-containing fluid accumulated in the holding vessel. The extracted nanoparticle-containing fluid is passed through a filtration module to separate a nanoparticle-containing retentate from a permeate, and the retentate is returned to the vessel. The filtration cycle can be repeated until a desired concentration of the nanoparticles is achieved in the holding vessel. In many embodiments, the generation of the nanoparticle-containing fluid and its filtration are performed concurrently. | 08-02-2012 |
20120258914 | COACERVATION PROCESS - Methods of forming compositions for the sustained release of water soluble active agents, including biologically active polypeptides and products produced by the process are described. Improved product characteristics and ease of scale-up can be achieved using a novel coacervation process wherein at least one coacervation agent is added to the mixture comprising the active agent and the polymer in at least two distinct stages. | 10-11-2012 |
20120263653 | METHODS AND SYSTEMS FOR GENERATING NANOPARTICLES - In one aspect, the present invention provides a process for forming polymeric nanoparticles, which comprises using a static mixer to create a mixed flowing stream of an anti-solvent, e.g., by introducing a liquid anti-solvent into a static mixer, and introducing a polymer solution into the mixed flowing anti-solvent stream such that controlled precipitation of polymeric nanoparticles occurs. The nanoparticles can then be separated from the anti-solvent steam. | 10-18-2012 |
20130253199 | Polymorphic Forms of Naltrexone - This invention relates to the discovery of novel polymorphic forms of naltrexone, including solvates, hydrates, anhydrous and other crystalline forms and combinations thereof. These novel forms of naltrexone impart advantages in pharmaceutical formulations incorporating them, including sustained release, or long acting, formulations. | 09-26-2013 |
20130273117 | METHODS AND SYSTEMS FOR GENERATING NANOPARTICLES - In one aspect, the present invention provides a process for forming polymeric nanoparticles, which comprises using a static mixer to create a mixed flowing stream of an anti-solvent, e.g., by introducing a liquid anti-solvent into a static mixer, and introducing a polymer solution into the mixed flowing anti-solvent stream such that controlled precipitation of polymeric nanoparticles occurs. The nanoparticles can then be separated from the anti-solvent stream. | 10-17-2013 |
20140010724 | Method For Fabricating Nanoparticles - Systems and methods are provided for filtering a fluid containing nanoparticles. The systems and methods generally include introducing a stream of the nanoparticle-containing fluid into a holding vessel, and extracting at least a part of a nanoparticle-containing fluid accumulated in the holding vessel. The extracted nanoparticle-containing fluid is passed through a filtration module to separate a nanoparticle-containing retentate from a permeate, and the retentate is returned to the vessel. The filtration cycle can be repeated until a desired concentration of the nanoparticles is achieved in the holding vessel. In many embodiments, the generation of the nanoparticle-containing fluid and its filtration are performed concurrently. | 01-09-2014 |
20140113137 | Methods And Systems For Generating Nanoparticles - In one aspect, the present invention provides a process for forming polymeric nanoparticles, which comprises using a static mixer to create a mixed flowing stream of an anti-solvent, e.g., by introducing a liquid anti-solvent into a static mixer, and introducing a polymer solution into the mixed flowing anti-solvent stream such that controlled precipitation of polymeric nanoparticles occurs. The nanoparticles can then be separated from the anti-solvent stream. | 04-24-2014 |
20140193507 | PREPARATION OF INJECTABLE SUSPENSIONS HAVING IMPROVED INJECTABILITY - Injectable compositions having improved injectability. The injectable compositions include microparticles suspended in an aqueous injection vehicle having a viscosity of at least 20 cp at 20° C. The increased viscosity of the injection vehicle that constitutes the fluid phase of the suspension significantly reduces in vivo injectability failures. The injectable compositions can be made by mixing dry microparticles with an aqueous injection vehicle to form a suspension, and then mixing the suspension with a viscosity enhancing agent to increase the viscosity of the fluid phase of the suspension to the desired level for improved injectability. | 07-10-2014 |
20140303200 | Polymorphic Forms of Naltrexone - This invention relates to the discovery of novel polymorphic forms of naltrexone, including solvates, hydrates, anhydrous and other crystalline forms and combinations thereof. These novel forms of naltrexone impart advantages in pharmaceutical formulations incorporating them, including sustained release, or long acting, formulations. | 10-09-2014 |
20140356249 | METHOD FOR FABRICATING NANOPARTICLES - Systems and methods are provided for filtering a fluid containing nanoparticles. The systems and methods generally include introducing a stream of the nanoparticle-containing fluid into a holding vessel, and extracting at least a part of a nanoparticle-containing fluid accumulated in the holding vessel. The extracted nanoparticle-containing fluid is passed through a filtration module to separate a nanoparticle-containing retentate from a permeate, and the retentate is returned to the vessel. The filtration cycle can be repeated until a desired concentration of the nanoparticles is achieved in the holding vessel. In many embodiments, the generation of the nanoparticle-containing fluid and its filtration are performed concurrently. | 12-04-2014 |
20150218178 | Polymorphic Forms Of Naltrexone - This invention relates to the discovery of novel polymorphic forms of naltrexone, including solvates, hydrates, anhydrous and other crystalline forms and combinations thereof. These novel forms of naltrexone impart advantages in pharmaceutical formulations incorporating them, including sustained release, or long acting, formulations. | 08-06-2015 |
Patent application number | Description | Published |
20080262584 | METHODS AND APPARATUS FOR FABRICATING LEADS WITH CONDUCTORS AND RELATED FLEXIBLE LEAD CONFIGURATIONS - MRI/RF compatible leads include at least one conductor, a respective conductor having at least one segment with a multi-layer stacked coil configuration. The lead can be configured so that the lead heats local tissue less than about 10 degrees Celsius (typically about 5 degrees Celsius or less) or does not heat local tissue when a patient is exposed to target RF frequencies at a peak input SAR of at least about 4 W/kg and/or a whole body average SAR of at least about 2 W/kg. Related leads and methods of fabricating leads are also described. | 10-23-2008 |
20080306327 | Apparatus Comprising a Drive Cable for a Medical Device - An article comprising a drive cable suitable for high-speed operation in an anatomy having small-radii bends is disclosed. The drive cables disclosed herein include one or more physical adaptations that enable them to be “tuned” to avoid large amplitude vibrations during operation. | 12-11-2008 |
20090062597 | Article Comprising an Impeller - An impeller for use in conjunction with a percutaneously-insertable blood pump or other rotatable equipment includes a blade that is segmented into a plurality of overlapping or abutting bladelets. In some embodiments, the bladelets are foldable and one side of each bladelet is concave. | 03-05-2009 |
20110040140 | Apparatus Comprising a Drive Cable for a Medical Device - An article comprising a drive cable suitable for high-speed operation in an anatomy having small-radii bends is disclosed. The drive cables disclosed herein include one or more physical adaptations that enable them to be “tuned” to avoid large amplitude vibrations during operation. | 02-17-2011 |
20120039713 | Article Comprising an Impeller II - An impeller for use in conjunction with a percutaneously-insertable blood pump or other rotatable equipment includes a blade that is segmented into a plurality of overlapping or abutting bladelets. In some embodiments, the bladelets are foldable and one side of each bladelet is concave. | 02-16-2012 |
20140276582 | SUBSTANCE DELIVERY DEVICES, SYSTEMS AND METHODS - A substance delivery device includes an elongated tubular body having opposing proximal and distal ends, and a diaphragm that is in slideable sealing engagement with an inside wall of the tubular body. The diaphragm is movable in opposite first and second directions within the tubular body. A substance is contained within the tubular body between the diaphragm and the tubular body distal end, and a slave fluid is contained within the tubular body between the diaphragm and the tubular body proximal end. When pressure is exerted on the slave fluid, the slave fluid causes the diaphragm to move and eject the substance through the tubular body distal end. | 09-18-2014 |