Patent application number | Description | Published |
20110063399 | PORTABLE PRINTER - A portable printer includes: a housing; a platen roller configured to convey a label sheet having a base sheet; a pinch roller configured to rotate following the platen roller via the base sheet; a supporting shaft configured to support the pinch roller; a shaft holder configured to hold the supporting shaft; a removing and inserting section configured to hold the shaft holder to be removable therefrom and insertable thereinto; a pawl section provided in the shaft holder, configured to resiliently hook to the removing and inserting section; a member holding section provided in the housing; and an urging member detachably attachable to the member holding section, nipped by the member holding section and the supporting shaft, and configured to apply pressing force on the platen roller to the pinch roller. | 03-17-2011 |
20120105564 | PRINTER AND MEDIUM - According to one embodiment, a printer includes a conveying mechanism, a first image forming unit, and a second image forming unit. The conveying mechanism conveys a medium. The first image forming unit forms an image with a non-temperature-sensitive ink whose color is not changed depending on a temperature, on the medium. The second image forming unit forms an image with a temperature-sensitive ink whose color is changed depending on a temperature, on the medium having the image with the non-temperature-sensitive ink formed thereon. | 05-03-2012 |
20120105566 | PRINTER, PRINT SYSTEM AND PRINTING METHOD - According to one embodiment, a printer includes a conveying mechanism, a first image forming unit and a coloring conversion mechanism. The conveying mechanism conveys a medium. The first image forming unit forms an image on the medium with a temperature-sensitive ink whose color changes depending on temperature. The coloring conversion mechanism converts a coloring state of the image with the temperature-sensitive ink by heating or cooling the image with the temperature-sensitive ink. | 05-03-2012 |
20120162339 | INK MEDIUM HOLDING MEMBER AND PRINTER - An ink medium holding member includes a holding unit and an indicating unit. The holding unit is configured to hold an elongated ink medium for supplying a temperature-sensitive ink whose color changes depending on temperature. The indicating unit is configured to indicate a changed color that the temperature-sensitive ink which is supplied from the ink medium held by the holding unit changes to. | 06-28-2012 |
20120162342 | PRINTER - A printer comprises a conveying unit configured to convey a medium. The printer includes an image forming unit provided in a conveyance path of the medium, the image forming unit being configured to form an image with a temperature-sensitive ink, whose color is changed depending on a temperature, on the medium. A cutter for cutting the medium is provided in the conveyance path downstream of a medium conveyance direction of the image forming unit. Further, a coloring conversion unit is provided in the conveyance path downstream of a medium conveyance direction of the cutter. The coloring conversion unit is configured to change a coloring state of the image of the temperature-sensitive ink by heating or cooling the image of the temperature-sensitive ink formed on the cut medium. | 06-28-2012 |
20120212559 | PORTABLE THERMAL PRINTER - According to one embodiment, a portable thermal printer is disclosed. The portable thermal printer comprises: a housing provided with a thermal printer head; a cover openably attached to an opening portion of the housing by a pivotal shaft, the cover being provided with a platen roller arranged to make contact with the thermal printer head when the opening portion of the housing is closed by the cover; and a drive power source provided within the housing. The drive power source, the pivotal shaft and the platen roller are connected by a belt mechanism. | 08-23-2012 |
20120313994 | PRINTER AND PRINT SYSTEM - According to one embodiment, a printer includes an image forming unit, a coloring conversion unit, and a deterring unit. The image forming unit forms an image from a temperature-sensitive ink whose color is changed depending on a temperature on a medium. The coloring conversion unit converts a coloring state of the image of the temperature-sensitive ink by heating or cooling the image of the temperature-sensitive ink. The deterring unit provided between the coloring conversion unit and the image forming unit deters an air heated or cooled by the coloring conversion unit from flowing toward the image forming unit. | 12-13-2012 |
20130278702 | PORTABLE THERMAL PRINTER - A portable thermal printer includes a housing and an anti-skew unit. The housing is provided with a thermal printer head and a platen roller, and is configured to convey a paper between the thermal printer head and the platen roller. The anti-skew unit inside the housing is configured to contact both side edges of the paper in a width direction to prevent the paper, which is being conveyed, from skewing, and the setting of the width of the paper by the anti-skew unit is configured to be adjustable from outside the housing. | 10-24-2013 |
20140168342 | PORTABLE THERMAL PRINTER - A portable thermal printer includes a housing and an anti-skew unit. The housing is provided with a thermal printer head and a platen roller, and is configured to convey a paper between the thermal printer head and the platen roller. The anti-skew unit inside the housing is configured to contact both side edges of the paper in a width direction to prevent the paper, which is being conveyed, from skewing, and the setting of the width of the paper by the anti-skew unit is configured to be adjustable from outside the housing. | 06-19-2014 |
Patent application number | Description | Published |
20090074434 | WASTE TONER COLLECTING DEVICE AND IMAGE FORMING APPARATUS - A waste toner collecting device includes a box that stores a waste toner unnecessary in image formation, a collection port that is provided in an upper part of a main body of the box, receives the waste toner, and drops the waste toner into the box, a triangular obstacle provided in a position opposed to a falling port for the waste toner and near a bottom surface in the box, and a sensor that is provided in a position lower than the collection port and higher than the obstacle and detects that an amount of the waste toner stored in the box reaches a predetermined amount. | 03-19-2009 |
20110218092 | SHEET FOLDING MECHANISM, SHEET POST-PROCESSING APPARATUS AND METHOD THEREOF - Certain embodiments provide a sheet folding mechanism including: a folding unit; a shaft; a pair of discharge rollers provided on the shaft; a pair of pinch rollers; a pair of clutches configured to transmit a rotational force only in the reverse direction; a pair of corrugation rollers, each of the corrugation rollers having a cam surface including a first diameter portion and a second diameter portion on an outer peripheral surface thereof, and an eccentric bearing to be fixed to each of the pair of clutches; a lock member configured to prevent the pair of corrugation rollers from idling; a drive unit configured to rotate the shaft; and a controller configured to cause the corrugation rollers to apply corrugation on the sheet bundle using any one of the first diameter portions and the second diameter portions according to the number of sheets in the sheet bundle. | 09-08-2011 |
20110260388 | SHEET PROCESSING APPARATUS, SHEET PROCESSING METHOD, AND SHEET FEEDING APPARATUS - According to one embodiment, a sheet processing apparatus includes: a stapler configured to staple sheets conveyed from an image forming apparatus; a guide plate configured to guide the sheets to the stapler in a conveying direction of the sheets; a longitudinal alignment roller configured to rotate, when guiding the sheets to the stapler, in a first direction to longitudinally align the sheets and rotate, when discharging the sheets subjected to the finishing, in a second direction opposite to the first direction; and a pressing member, one end and the other end of which are attached to the guide plate and a main body section of which is curved in an arc shape toward the longitudinal alignment roller and is in contact with the longitudinal alignment roller. | 10-27-2011 |
20120025456 | SHEET PROCESSING APPARATUS AND SHEET PROCESSING METHOD - A sheet processing apparatus includes a control section configured to control a rotating speed of a longitudinal alignment roller, which is set on a recording medium stacking surface of a processing tray and configured to align a recording medium in a longitudinal direction, such that acceleration and deceleration of the rotating speed is performed at least twice during one longitudinal alignment operation and a paddle including a striking paddle configured to strike the recording medium, a dropping paddle configured to drop the recording medium, a draw-in paddle configured to draw the recording medium in a direction of a stopper, a dropping-paddle supporting member configured to support the dropping paddle from the back in a rotating direction of the paddle, and a draw-in-paddle supporting member configured to support the draw-in paddle from the back in the rotating direction. | 02-02-2012 |
20130003138 | SHADING DEVICE FOR IMAGE READING SECTION - A shading device includes: a shading member to pass a conveying path for conveying a recoding medium to plural image reading sections and reach the plural image reading sections; and a moving member to move the shading member between the plural image reading sections and a retracted position on the outside of the conveying path. | 01-03-2013 |
Patent application number | Description | Published |
20110098450 | Antibody Molecules - The present invention provides pharmaceutical compositions comprising second-generation molecules that are superior than TOCILIZUMAB, by altering the amino acid sequences of the variable and constant regions of TOCILIZUMAB, which is a humanized anti-IL-6 receptor IgG1 antibody, to enhance the antigen-neutralizing ability and increase the pharmacokinetics, so that the therapeutic effect is exerted with a less frequency of administration, and the immunogenicity, safety and physicochemical properties (stability and homogeneity) are improved. The present invention also provides methods for producing these pharmaceutical compositions. The present inventors have successfully generated second-generation molecules that are superior to TOCILIZUMAB by appropriately combining amino acid sequence alterations in the CDR domains, variable regions, and constant regions. | 04-28-2011 |
20110111406 | ANTIGEN-BINDING MOLECULE CAPABLE OF BINDING TO TWO OR MORE ANTIGEN MOLECULES REPEATEDLY - The present inventors discovered that antibodies having weaker antigen-binding activity at the early endosomal pH in comparison with that at the pH of plasma are capable of binding to multiple antigen molecules with a single antibody molecule, have long half-lives in plasma, and have improved durations of time in which they can bind to antigen. | 05-12-2011 |
20120253016 | ANTIBODY MOLECULES THAT BIND TO IL-6 RECEPTOR - The present invention provides pharmaceutical compositions comprising second-generation molecules that are superior than TOCILIZUMAB, by altering the amino acid sequences of the variable and constant regions of TOCILIZUMAB, which is a humanized anti-IL-6 receptor IgG1 antibody, to enhance the antigen-neutralizing ability and increase the pharmacokinetics, so that the therapeutic effect is exerted with a less frequency of administration, and the immunogenicity, safety and physicochemical properties (stability and homogeneity) are improved. The present invention also provides methods for producing these pharmaceutical compositions. The present inventors have successfully generated second-generation molecules that are superior to TOCILIZUMAB by appropriately combining amino acid sequence alterations in the CDR domains, variable regions, and constant regions. | 10-04-2012 |
20130011866 | ANTIGEN-BINDING MOLECULE CAPABLE OF BINDING TO TWO OR MORE ANTIGEN MOLECULES REPEATEDLY - The present inventors discovered that antibodies having weaker antigen-binding activity at the early endosomal pH in comparison with that at the pH of plasma are capable of binding to multiple antigen molecules with a single antibody molecule, have long half-lives in plasma, and have improved durations of time in which they can bind to antigen. | 01-10-2013 |
20130131319 | ANTIBODIES WITH MODIFIED AFFINITY TO FCRN THAT PROMOTE ANTIGEN CLEARANCE - An objective of the present invention is to provide methods for facilitating antigen-binding molecule-mediated antigen uptake into cells, methods for facilitating the reduction of antigen concentration in plasma, methods for increasing the number of antigens to which a single antigen-binding molecule can bind, methods for improving pharmacokinetics of antigen-binding molecules, antigen-binding molecules improved for facilitated antigen uptake into cells, antigen-binding molecules capable of facilitating the reduction of antigen concentration in plasma, antigen-binding molecules capable of repeatedly binding to antigens, antigen-binding molecules with improved pharmacokinetics, pharmaceutical compositions comprising such an antigen-binding molecule, and methods for producing those described above. The present inventors discovered that antigen uptake into cells is facilitated by an antibody having human FcRn-binding activity at the plasma pH and a lower antigen-binding activity at the early endosomal pH than at the plasma pH; such antibodies can increase the number of antigens to which a single antibody molecule can bind; the reduction of antigen in plasma can be facilitated by administering such an antibody; and antibody pharmacokinetics can be improved by using such antibodies. | 05-23-2013 |
20130303396 | ANTIGEN-BINDING MOLECULE CAPABLE OF BINDING TO TWO OR MORE ANTIGEN MOLECULES REPEATEDLY - The present inventors discovered that antibodies having weaker antigen-binding activity at the early endosomal pH in comparison with that at the pH of plasma are capable of binding to multiple antigen molecules with a single antibody molecule, have long half-lives in plasma, and have improved durations of time in which they can bind to antigen. | 11-14-2013 |
20130336963 | ANTIGEN-BINDING MOLECULE CAPABLE OF BINDING TO TWO OR MORE ANTIGEN MOLECULES REPEATEDLY - The present inventors discovered that antibodies having weaker antigen-binding activity at the early endosomal pH in comparison with that at the pH of plasma are capable of binding to multiple antigen molecules with a single antibody molecule, have long half-lives in plasma, and have improved durations of time in which they can bind to antigen. | 12-19-2013 |
20140234340 | ANTIGEN-BINDING MOLECULE CAPABLE OF BINDING TO PLURALITY OF ANTIGEN MOLECULES REPEATEDLY - An objective of the present invention is to provide methods for promoting antigen uptake into cells by antigen-binding molecules, methods for increasing the number of times of antigen binding by one antigen-binding molecule, methods for promoting reduction of the antigen concentration in plasma by administering antigen-binding molecules, and methods for improving the plasma retention of an antigen-binding molecule, as well as antigen-binding molecules that allow enhanced antigen uptake into cells, antigen-binding molecules having an increased number of times of antigen binding, antigen-binding molecules that can promote reduction of the antigen concentration in plasma when administered, antigen-binding molecules with improved plasma retention, pharmaceutical compositions comprising the above antigen-binding molecules, and methods for producing them. The present inventors revealed that the above objective can be achieved by using antigen-binding molecules that show calcium-dependent antigen-antibody reaction. | 08-21-2014 |
20140271617 | ION CONCENTRATION-DEPENDENT BINDING MOLECULE LIBRARY - Disclosed is a library consisting essentially of a plurality of antigen-binding molecules differing in sequence from each other, wherein an antigen-binding domain in each of the antigen-binding molecules comprises at least one amino acid residue that changes the antigen-binding activity of the antigen-binding molecule depending on ion concentration conditions. Also disclosed are a composition comprising a plurality of polynucleotide molecules each encoding the antigen-binding molecules, a composition comprising a plurality of vectors each comprising the polynucleotide molecules, a method for selecting the antigen-binding molecules, a method for isolating the polynucleotide molecules, a method for producing the antigen-binding molecules, and a pharmaceutical composition comprising any of the antigen-binding molecules. | 09-18-2014 |
Patent application number | Description | Published |
20100111947 | PHARMACEUTICAL COMPOSITION COMPRISING ANTIBODY COMPOSITION WHICH SPECIFICALLY BINDS TO GANGLIOSIDE GM2 - The present invention provides a pharmaceutical composition which is effective for treating multiple myeloma. The present invention relates to a pharmaceutical composition comprising a combination of an antibody composition which specifically binds to ganglioside GM2 or an antibody fragment thereof and at least one agent. | 05-06-2010 |
20110262431 | PHARMACEUTICAL COMPOSITION COMPRISING ANTIBODY COMPOSITION WHICH SPECIFICALLY BINDS TO CCR4 - A pharmaceutical composition, comprising an antibody composition which specifically binds to human CC chemokine receptor 4 (hereinafter also referred to as CCR4) and at least one medicament; and a pharmaceutical composition for administering in combination of a recombinant antibody against CCR4 and at least one medicament are required. The present invention can provide a pharmaceutical composition comprising a recombinant antibody against CCR4 and at least one medicament; and a pharmaceutical composition for administering in combination of a recombinant antibody against CCR4 and at least one medicament. | 10-27-2011 |
20120207818 | COMPOSITION FOR SUPPRESSING EXPRESSION OF TARGET GENE - The present invention provides a composition that comprises a liposome encapsulating a double-stranded nucleic acid molecule,
| 08-16-2012 |
20120244210 | COMPOSITION FOR SUPPRESSING EXPRESSION OF TARGET GENE - The present invention provides a composition that comprises a lipidparticle encapsulating a double-stranded nucleic acid molecule,
| 09-27-2012 |
20130287768 | PHARMACEUTICAL COMPOSITION COMPRISING ANTIBODY COMPOSITION WHICH SPECIFICALLY BINDS TO CCR4 - A pharmaceutical composition, comprising an antibody composition which specifically binds to human CC chemokine receptor 4 (hereinafter also referred to as CCR4) and at least one medicament; and a pharmaceutical composition for administering in combination of a recombinant antibody against CCR4 and at least one medicament are required. The present invention can provide a pharmaceutical composition comprising a recombinant antibody against CCR4 and at least one medicament; and a pharmaceutical composition for administering in combination of a recombinant antibody against CCR4 and at least one medicament. | 10-31-2013 |
20140044755 | RNAi PHARMACEUTICAL COMPOSITION FOR SUPPRESSING EXPRESSION OF KRAS GENE - The present invention provides a composition for suppressing the expression of a KRAS gene, comprising a lipid particle containing, as a drug, a double-stranded nucleic acid having an antisense strand having a sequence of bases complementary to the sequence of at least 19 continuous bases of any one KRAS gene's mRNA of sequence Nos. 1 to 3; and | 02-13-2014 |