Irazoqui
Fernando José Irazoqui, Cordoba AR
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20100297159 | THOMSEN-FRIEDENREICH DISACCHARIDE MODIFIED IMMUNOGEN (TFD), PREPARATION PROCEDURE, COMPOSITIONS COMPRISING IT, USES, AND TREATMENT METHODS - Modified Thomsen-Friedenreich disaccharide (TFD) immunogen, preparation procedure, compositions containing it, uses, and treatment methods. More specifically, the present invention refers to a immunogen obtained by modifying TFD, and comprising the general formula D-TFD-Lys(n)-C, wherein D is a hydrophobic terminal residue, TFD is disaccharide Galβ3GalNAcα; Lys(n) is a lysine connector, and n is an integer between 1 and 5, and C is a carrier. In a preferred embodiment, the modified invention immunogen comprises the general formula BzlαTFD-Lys5-KLHs, wherein Bzl is benzyl, TFD is disaccharide Galβ3GalNAcα; Lys5 is penta-lysine, and KLHs is succinilated Keyhole limpets hemocyanin. | 11-25-2010 |
Fernando José Irazoqui, Cordoba AR
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20100297159 | THOMSEN-FRIEDENREICH DISACCHARIDE MODIFIED IMMUNOGEN (TFD), PREPARATION PROCEDURE, COMPOSITIONS COMPRISING IT, USES, AND TREATMENT METHODS - Modified Thomsen-Friedenreich disaccharide (TFD) immunogen, preparation procedure, compositions containing it, uses, and treatment methods. More specifically, the present invention refers to a immunogen obtained by modifying TFD, and comprising the general formula D-TFD-Lys(n)-C, wherein D is a hydrophobic terminal residue, TFD is disaccharide Galβ3GalNAcα; Lys(n) is a lysine connector, and n is an integer between 1 and 5, and C is a carrier. In a preferred embodiment, the modified invention immunogen comprises the general formula BzlαTFD-Lys5-KLHs, wherein Bzl is benzyl, TFD is disaccharide Galβ3GalNAcα; Lys5 is penta-lysine, and KLHs is succinilated Keyhole limpets hemocyanin. | 11-25-2010 |
Pedro Irazoqui, Lafayatte, IN US
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20090132003 | Wireless Electrical Stimulation of Neural Injury - An apparatus for wireless electrical stimulation of a neural injury includes a first electronic implant ( | 05-21-2009 |
Pedro Irazoqui, Lafayette, IN US
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20080306571 | Devices For Treatment of Central Nervous System Injuries - A device for stimulating axon growth of the nerve cells in the spinal cord of mammals includes a device having a DC stimulus generator ( | 12-11-2008 |
20090254148 | Telemetrically Controllable System for Treatment of Nervous Sytem Injury - An apparatus ( | 10-08-2009 |
20110257715 | FLEXIBLE NEURAL PROBE FOR MAGNETIC INSERTION - A neural probe deployment system comprising a magnetic probe, a magnetic field generator acting on the magnetic probe, a first guiding tube disposed on a first side of the magnetic field generator, wherein the magnetic probe is loaded inside the first guiding tube, and a second guiding tube disposed on a second side of the magnetic field generator, wherein activation of the magnetic field generator propels the magnetic probe from the first guiding tube through the second guiding tube, thereby deploying the magnetic probe. | 10-20-2011 |
20120083708 | ADAPTIVE REAL-TIME SEIZURE PREDICTION SYSTEM AND METHOD - A real-time seizure prediction system. The system includes an implantable electrode configured to transmit an analog neuro-electrophysiological signal from a subject, an analog-to-digital converter configured to convert the analog neuro-electrophysiological signal to a digital neuro-electrophysiological signal based on a predetermined sampling rate, a processor configured to perform following steps during a period defined by the predetermined sampling rate: calculate a plurality of autocorrelation coefficients of the digital neuro-electrophysiological signal for a first predetermined number of samples, calculate a predicted future value of the digital neuro-electrophysiological data based on the plurality of autocorrelation coefficients and the first predetermined number of samples of the digital neuro-electrophysiological data, compare the predicted future value with an actual future value of the digital neuro-electrophysiological data to determine a prediction error, calculate a threshold based on a mean squared value of the prediction error for the first predetermined number of samples and based on a proportionality constant, generate a seizure prediction signal if the prediction error remains above the threshold for a second predetermined number of samples, and a warning device configured to receive the seizure prediction signal and generate an alert. | 04-05-2012 |
20140088379 | WIRELESSLY-POWERED IMPLANTABLE EMG RECORDING SYSTEM - Apparatus and methods for the measurement and transmission of data pertaining to the tissue of an animal. In one embodiment, there is an implantable device that is wirelessly powered and also wirelessly transmits data. Preferably, the implant measures neuromuscular activity. | 03-27-2014 |
Pedro Irazoqui, West Lafayette, IN US
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20110282233 | LOW-POWER REAL-TIME SEIZURE DETECTION SYSTEM - A method for detecting an approaching seizure is disclosed. The method includes receiving an analog neurosignal from an electrode, comparing the analog neurosignal with a predetermined amplitude threshold to generate a plurality of digital transitions corresponding to the analog neurosignal transitioning from a first level below the predetermined amplitude threshold to a second level above the predetermined amplitude threshold, generating a plurality of comparator signals, each comparator signal of the plurality of comparator signals corresponding to a comparison of a length of time between a pair of digital transitions of the plurality of digital transitions and a predetermined temporal threshold, and generating a seizure detection signal if at least two of the comparator signals of the plurality of comparator signals are enabled. A seizure detection system for detecting an approaching seizure is also disclosed. | 11-17-2011 |
20140243714 | Method and Apparatus for Closed-Loop Control of Nerve Activation - The present disclosure is directed to a method and apparatus to autonomously stimulate a plurality of nerve fiber groups. The method and apparatus predicts stimulus parameters that can activate 0-100% of the nerve fiber groups selectively according to a patient's characteristics and proportional to therapeutic outcomes, such as determined by experimental data. The method and apparatus may further be configured to input experimental third-party data to obtain a high efficacy from a patient without invasive neurosurgery. | 08-28-2014 |
Pedro P. Irazoqui, West Lafayette, IN US
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20140296687 | PRESSURE SENSORS FOR SMALL-SCALE APPLICATIONS AND RELATED METHODS - Certain pressure sensor devices are much smaller than prior art devices, yet are at least as sensitive as the prior art devices. A capacitive pressure sensor can include a flexible substrate that permits bending of a pressure sensing region without significantly affecting operation thereof. The pressure sensor can include a flexible membrane in which an electrode is sandwiched between two layers of polymeric material. The sandwiched electrode can be extremely close to a reference electrode so as to provide for highly sensitive capacitance readings, yet the membrane can be restricted from contacting the reference electrode under high pressure conditions. | 10-02-2014 |
Pedro P. Irazoqui, Lafayette, IN US
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20090069648 | INTRA-OCCULAR PRESSURE SENSOR - A system is provided for monitoring intraocular pressure, the system comprising: a sensor package configured to be disposed in the suprachoroidal space of a patient's eye; a pressure sensor; a wireless transceiver disposed within the sensor package and coupled to the pressure sensor; an external transceiver, the external receiver being wirelessly coupled to the wireless transceiver when the transceiver is disposed proximate to the patient's eye. | 03-12-2009 |
20100137694 | RADIO TRANSPARENT SENSOR IMPLANT PACKAGE - A system is provided for the packaging of wireless electronics in a mammalian body, the system comprising: a package configured in a shape suitable for implantation in that body; the package being configured from a biocompatible material; and that biocompatible material having a high degree of radio wave transparency. | 06-03-2010 |
20100179449 | MINIATURE STENT-BASED IMPLANTABLE WIRELESS MONITORING DEVICES - A system is provided for the transmission of in vivo arterial pressure, the system comprising: an a pressure sensor whereby in vivo arterial pressure data is collected; a wireless transmitter, whereby the in vivo arterial pressure data is transmitted to be received disposed externally to a patient in which the system is disposed; a stent body, the stent body having an integral antenna, and a power source, whereby power is supplied to the system. | 07-15-2010 |
20140031905 | BURST PULSE TISSUE STIMULATION METHOD AND APPARATUS - A method for stimulating nerve tissue of an organism includes a step of electrically connecting an electrical signal source to at least a first nerve. The method also includes applying a periodically repeating burst pulse signal pattern to the first nerve. The burst pulse signal pattern has a pattern frequency defining a frequency of repetition of the burst pulse signal pattern and a pattern duty cycle defining a first time period of the burst pulse signal pattern, the burst pulse signal pattern having a plurality of pulses, the pulses having a frequency within the pattern that exceeds the pattern frequency by at least an order of magnitude. | 01-30-2014 |
20140088400 | INTRA-OCCULAR PRESSURE SENSOR - A system is provided for monitoring intraocular pressure, the system comprising: a sensor package configured to be disposed in the suprachoroidal space of a patient's eye; a pressure sensor; a wireless transceiver disposed within the sensor package and coupled to the pressure sensor; an external transceiver, the external receiver being wirelessly coupled to the wireless transceiver when the transceiver is disposed proximate to the patient's eye. | 03-27-2014 |