Patent application number | Description | Published |
20100114043 | Hollow Type Microneedle and Methods for Preparing It - Disclosed herein are hollow microneedles and a fabrication method thereof. The microneedles are small in diameter and are long and hard enough to pass through the stratum corneum. Therefore, the hollow microneedle of the present invention can be used in blood sampling or drug injection through the skin. | 05-06-2010 |
20110240201 | METHOD OF MANUFACTURING MICROSTRUCTURE - Provided are methods of manufacturing microstructures, in which at least one viscous composition each containing at least one active ingredient is disposed directly or indirectly on a first substrate and/or a second substrate and the viscous composition(s) is elongated between the first and second substrates. The methods are simpler and more cost-effective. | 10-06-2011 |
20140364764 | DEVICE FOR COLLECTING BODY FLUIDS - The present invention relates to a device for collecting body fluids, the device comprising: (a) an internal pressure adjustment means for adjusting the internal pressure of the device, and the internal pressure adjustment means has an internal space and is made of an elastic deformable material; (b) a fluid accommodation means, which is openly connected to the internal pressure adjustment means, for accommodating body fluids collected from the human body; and (c) a perforation means which is connected to the fluid accommodation means, is located at the lower part of the device, and comprises a hollow microstructure for forming an opening on the body. | 12-11-2014 |
20150112282 | HOLLOW MICRONEEDLE AND SUBRETINAL SYRINGE FOR SUBRETINAL INJECTION OR EXTRACTION - The present invention relates to a method for manufacturing a hollow microneedle for subretinal injection or extraction. The microneedle for subretinal injection or extraction is made of metal, thereby providing the strength and force for penetrating the sclera and retina. Due to the length and the angle of curvature, the microneedle for subretinal injection or extraction of the present invention can reach a suitable subretinal site, such as the midperiphery at which optic nerves are accumulated, and thus the present invention is effective for delivering a drug and can enhance the effectiveness of the drug. | 04-23-2015 |
20150126633 | METHOD FOR FABRICATION OF POROUS FIBROUS MICROSTRUCTURE WITH VARIOUS 3-DIMENSIONAL STRUCTURES - The present invention relates to a method for fabricating a three-dimensional porous fibrous microstructure, various three-dimensional porous fibrous microstructures fabricated by the method, an apparatus for detecting a biological marker and a drug delivery system comprising the microstructure. The porous fibrous microstructure of the present invention has excellent interconnectivity between pores and micropores and captures and delivers target particles at high efficiency, and thus can be usefully applied to biomedical applications including the detection of a biomarker and drug delivery. | 05-07-2015 |
20150224293 | METHOD FOR MANUFACTURING MICROSTRUCTURE USING NEGATIVE PRESSURE AND MICROSTRUCTURE MANUFACTURED THEREFOR - The present invention is directed to a method for manufacturing a microstructure, the method comprising: (a) placing a viscous composition on a substrate; and (b) applying negative pressure to the viscous composition to induce an extension of the viscous composition, thereby forming a microstructure, and a microstructure manufactured therefor. According to the present invention, a microstructure can be formed without performing a heat treatment by applying a negative pressure. Consequently, it is possible to mount on a microstructure various materials that are sensitive to heat and easily damaged or degenerated. According to the present invention, a microstructure can be manufactured in a non-contacting manner, that is, without being contacted with conventionally used another structure such as a mould or filler. This leads to overcome a loss caused during a process of separating a microstructure in contact or a cutting process involving a physical destruction after the completion of moulding a microstructure and limit on the production yield. | 08-13-2015 |
20150328443 | MICROSTRUCTURE-BASED DRUG DELIVERY SYSTEM COMPRISING MICROPOROUS STRUCTURE - Disclosed are a microstructure-based drug delivery system comprising a microporous structure and a method for manufacturing the same, and more specifically, a detachable microstructure-based drug delivery system using a microporous structure layer and a method for manufacturing the same, thereby skipping a drying step which is essential for the manufacturing process of the existing biodegradable microneedle, and solving the problem in that the hardness of the microneedle is reduced when the microneedle contains drugs, failing to penetrate the skin. Here, the microstructure is implantable in the body through the insertion into the body and detachment from the microporous structure, and the detachable microstructure can be applied to wrinkled (skin movement) and corrugated parts through a detachment function thereof. | 11-19-2015 |