Hulme
A. Keith Hulme, Essex GB
Patent application number | Description | Published |
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20130070236 | METHOD FOR DETERMINING THE PATH LENGTH OF A SAMPLE AND VALIDATING THE MEASUREMENT OBTAINED - A for traceably determining an unknown optical path length of a sample in an optical measuring device comprises the steps of: providing a drop analyser connected to a standard spectrophotometer; providing a certified reference material contained in first and second closed high accuracy cuvettes; measuring absorbance of the certified reference material to obtain a first absorbance measurement for the first specified path length; measuring absorbance of the certified reference material for a second path length to obtain a second absorbance measurement; using a dropping device to drop a specified volume of the solvent on an optical surface so that the path length of the specified volume can be determined by reference to the first and second absorbance measurement; and using the dropping device to drop the same volume of sample as the specified volume of solvent on the optical measuring device. | 03-21-2013 |
Alan Keith Hulme, Hainault GB
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20090219527 | Apparatus and Method for Adapting Conventional Cuvettes for Use in a Vertical Light Beam Spectrophotometer - The invention relates to an apparatus and method for adapting conventional spectrophotometer cuvettes for use in a vertical light beam spectrophotometer. | 09-03-2009 |
Christopher John Hulme, Wuerenlingen CH
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20080306714 | METHOD FOR DIGITALIZING THREE-DIMENSIONAL COMPONENTS - A three-dimensional component ( | 12-11-2008 |
20100041322 | METHOD AND DEVICE FOR PIN REMOVAL IN A CONFINED SPACE - A method for drilling or cutting a pin surrounded by solid material includes the use of a water jet tool having a nozzle that is arranged at an angle with respect to a main body of the water jet tool. The water jet is directed over a portion of the surface of the pin, and removes that portion thereby fragmenting the pin. In order to minimise damage to the surrounding material, the portions removed touches the interface between the pin and the surrounding solid material at a minimal number of points and over a minimal extent of the interface. The method is applicable in particular to the removal of pins used in a press-fit for the securing of blades on a turbine rotor. The method facilitates “in situ” removal of pins within a confined space in a short time and at reduced cost. | 02-18-2010 |
Edward Christopher Hulme, London GB
Patent application number | Description | Published |
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20110046351 | MUTANT PROTEINS AND METHODS FOR SELECTING THEM - A method for selecting a membrane protein with increased stability, the method comprising: a) providing one or more mutants of a parent membrane protein in a membrane-containing composition, wherein the one or more mutants are exposed to an amount of a membrane destabilising agent which is effective to destabilise the parent membrane protein in-situ, b) determining whether the or each mutant membrane protein has increased stability with respect to its structure and/or a biological activity compared to the stability of the parent membrane protein with respect to its structure and/or the same biological activity, and c) selecting the one or more mutants which have increased stability compared to the stability of the parent membrane protein. | 02-24-2011 |
Keith Hulme, Essex GB
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20100327182 | FLUORESCENCE MEASUREMENT CELL - A cell for measuring the fluorescence of a sample comprising an incident wall surface ( | 12-30-2010 |
20110013182 | REFERENCE CELL - Reference cell ( | 01-20-2011 |
Keith Hulme, Hainault GB
Patent application number | Description | Published |
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20150159197 | PCR VALIDATION TUBES - This invention relates to a PCR fluorescence reference standard and to a method for manufacturing a PCR fluorescence reference standard. The PCR fluorescence reference standard comprises a fluorophore suspended in a thermoplastic polymer matrix. The PCR fluorescence reference standard of the invention has a greater shelf life than fluorophores dissolved in a solution and can advantageously be used to validate a fluorescence signal obtained in a thermal cycler. | 06-11-2015 |
20150160132 | PCR VALIDATION TUBES - This invention relates to a PCR fluorescence reference standard and to a method for manufacturing a PCR fluorescence reference standard. The PCR fluorescence reference standard comprises a fluorophore suspended in a thermoplastic polymer matrix. The PCR fluorescence reference standard of the invention has a greater shelf life than fluorophores dissolved in a solution and can advantageously be used to validate a fluorescence signal obtained in a thermal cycler. | 06-11-2015 |
Nathan Hulme, Essex GB
Patent application number | Description | Published |
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20130070236 | METHOD FOR DETERMINING THE PATH LENGTH OF A SAMPLE AND VALIDATING THE MEASUREMENT OBTAINED - A for traceably determining an unknown optical path length of a sample in an optical measuring device comprises the steps of: providing a drop analyser connected to a standard spectrophotometer; providing a certified reference material contained in first and second closed high accuracy cuvettes; measuring absorbance of the certified reference material to obtain a first absorbance measurement for the first specified path length; measuring absorbance of the certified reference material for a second path length to obtain a second absorbance measurement; using a dropping device to drop a specified volume of the solvent on an optical surface so that the path length of the specified volume can be determined by reference to the first and second absorbance measurement; and using the dropping device to drop the same volume of sample as the specified volume of solvent on the optical measuring device. | 03-21-2013 |
Nathan Hulme, Hainault GB
Patent application number | Description | Published |
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20150159197 | PCR VALIDATION TUBES - This invention relates to a PCR fluorescence reference standard and to a method for manufacturing a PCR fluorescence reference standard. The PCR fluorescence reference standard comprises a fluorophore suspended in a thermoplastic polymer matrix. The PCR fluorescence reference standard of the invention has a greater shelf life than fluorophores dissolved in a solution and can advantageously be used to validate a fluorescence signal obtained in a thermal cycler. | 06-11-2015 |
20150160132 | PCR VALIDATION TUBES - This invention relates to a PCR fluorescence reference standard and to a method for manufacturing a PCR fluorescence reference standard. The PCR fluorescence reference standard comprises a fluorophore suspended in a thermoplastic polymer matrix. The PCR fluorescence reference standard of the invention has a greater shelf life than fluorophores dissolved in a solution and can advantageously be used to validate a fluorescence signal obtained in a thermal cycler. | 06-11-2015 |