Patent application number | Description | Published |
20110126310 | TRANSGENIC MAIZE EVENT MON 87427 AND THE RELATIVE DEVELOPMENT SCALE - The invention provides transgenic maize event MON 87427 and plants, plant cells, seeds, plant parts, and commodity products derived from event MON 87427. The invention also provides nucleotides specific for transgenic maize event MON 87427 and plants, plant cells, seeds, plant parts, and commodity products comprising nucleotides specific for transgenic maize event MON 87427. The invention also provides methods related to transgenic maize event MON 87427 and to the Roundup® Hybridization System (RHS). The invention also provides a Relative Development Scale useful for monitoring and determining reproductive development in maize that reconciles developmental differences across various maize varieties. This is useful for determining the optimal timing of a treatment regimen in which tassel development stage is an important factor, including various methods in making hybrid seed. | 05-26-2011 |
20110191898 | Compositions and Methods for Enhanced Amino Acid Levels in Plants - Threonine is an essential amino acid for humans and in the animal feed industry where its levels in feed rations can significantly impact the cost of production of important meat sources, such as swine and poultry. Threonine as well as essential amino acids lysine and methionine are all synthesized via the aspartate family pathway. Aspartate kinase (AK) is the first enzyme in the pathway, and catalyzes the ATP-dependent phosphorylation of aspartate to form β-aspartyl phosphate. AK constitutes the main regulatory step controlling the metabolic flux through the pathway, and is subject to end product inhibition by Lys and/or Thr. The current invention provides a method to produce a transgenic high free threonine soybean via the overexpression of feed-back-resistant AK enzymes in developing soybean plants and seeds. These modifications provide a method to enhance both plant nitrogen metabolism and crop growth performance. | 08-04-2011 |
20130007908 | METHODS AND COMPOSITIONS FOR SELECTIVE REGULATION OF PROTEIN EXPRESSION - The invention provides methods and compositions for selectively suppressing the expression of a recombinant protein in a male reproductive tissue of a transgenic plant. The invention also provides methods and compositions for inducing male sterility in a transgenic plant. Plants, plant cells, plant parts, seeds, and commodity products including such compositions are aspects of the invention. | 01-03-2013 |
20140109250 | TRANSGENIC MAIZE EVENT MON 87427 AND THE RELATIVE DEVELOPMENT SCALE - The invention provides transgenic maize event MON 87427 and plants, plant cells, seeds, plant parts, and commodity products derived from event MON 87427. The invention also provides nucleotides specific for transgenic maize event MON 87427 and plants, plant cells, seeds, plant parts, and commodity products comprising nucleotides specific for transgenic maize event MON 87427. The invention also provides methods related to transgenic maize event MON 87427 and to the Roundup® Hybridization System (RHS). The invention also provides a Relative Development Scale useful for monitoring and determining reproductive development in maize that reconciles developmental differences across various maize varieties. This is useful for determining the optimal timing of a treatment regimen in which tassel development stage is an important factor, including various methods in making hybrid seed. | 04-17-2014 |
Patent application number | Description | Published |
20080286229 | METHOD TO PROMOTE HAIR GROWTH AND/OR DELAY OR TREAT HAIR LOSS BY ADMINISTERING A TGF-BETA ANTAGONIST OR INHIBITOR - The present invention provides methods for promoting hair growth and/or treating or preventing hair loss (alopecia) by contacting the cells with a TGF-β antagonist or inhibitor either alone or in combination with other alopecia-inhibiting compounds. | 11-20-2008 |
20090062247 | METHODS FOR INHIBITING TGF-beta - The present invention provides methods for inhibiting or blocking TGF-β activity in cells and/or tissues expressing TGF-β comprising, contacting cells and/or tissues expressing TGF-β with an amount of cholesterol or cholesterol derivative effective to inhibit the activity of TGF-β. The present invention further provides a method for treating a condition associated with overactivity of TGF-β or negative regulation in normal physiology by TGF-β in a subject in need of treatment, comprising contacting cells and/or tissue overexpressing TGF-β in the subject with an amount of cholesterol or cholesterol derivative effective to inhibit activity of TGF-β thereby treating the condition. In a preferred embodiment, the cholesterol derivative is oxidized 7-DHC. | 03-05-2009 |
20100075923 | METHOD OF ENHANCING TGF-BETA SIGNALLING - The present invention is directed to a method of enhancing TGF-β signaling in a subject comprising administering to said subject a clathrin-dependent endocytosis inhibitor in an amount sufficient to enhance TGF-β signaling. In another aspect, the invention is directed to a method of treating a condition associated with decreased TGF-β signaling in a patient in need thereof comprising administering to said patient a clathrin-dependent endocytosis inhibitor in a therapeutically effective amount. | 03-25-2010 |
20110008248 | Peptide Antagonists of TGF-Beta Family Members and Therapeutic Uses Thereof - This invention is drawn to methods of using peptide-based antagonists of TGF-beta to facilitate the healing of cutaneous wounds that includes burns, lacerations and scrapes. The administration of peptide TGF-beta antagonists to wounds results in reduced scarring, wound contraction and deposition of extracellular matrix components, and increased rates of reepithelialization during wound healing. | 01-13-2011 |
20140271723 | ADJUVANT COMPOSITIONS AND METHODS OF USING THEREOF - The present invention relates to adjuvant compositions, vaccine compositions, and methods of enhancing an immune response to an antigen. | 09-18-2014 |
Patent application number | Description | Published |
20140320048 | System and Method for Reducing Radiated Emissions in an Integrated Motor Drive - A motor drive, configured to be mounted to a motor, includes improvements to input circuits configured to receive and/or transfer power within the motor drive to reduce emissions over prior art motor drives. According to a first embodiment of the invention, the motor drive includes a voltage balancing circuit which utilizes surface mount capacitors having a voltage rating of at least 2772 VDC and, preferably, of at least 5000 VDC. According to another embodiment of the invention, the power supply includes a planar transformer wherein the primary and the secondary coils are uniformly formed by traces on the circuit board. | 10-30-2014 |
20140354206 | System and Method for Temperature Estimation in an Integrated Motor Drive - A system to monitor the temperature of power electronic devices in a motor drive includes a base plate defining a planar surface on which the electronic devices and/or circuit boards within the motor drive may be mounted. The power electronic devices are mounted to the base plate through the direct bond copper (DBC). A circuit board is mounted to the base plate which includes a temperature sensor mounted on the circuit board proximate to the power electronic devices. The temperature sensor generates a digital signal corresponding to the temperature measured by the sensor. A copper pad is included between each layer of the circuit board and between the first layer of the circuit board and the sensor. The circuit board also includes vias extending through each layer of the board. The copper pads and vias establish a thermally conductive path between the temperature sensor and the base plate. | 12-04-2014 |
20140361613 | System and Method for Reducing Reactive Current on a Common DC Bus with Multiple Inverters - A system configured to reduce the amplitude of reactive current present on a DC bus shared by multiple inverters is disclosed. The start of the switching period for the modulation routines of each inverter is synchronized, and a carrier phase angle is determined for a carrier signal within each of the inverters. The modulation routine of each inverter generates a reactive current on the shared DC bus. By controlling the carrier phase angle for each inverter, the reactive current of a first inverter may be generated at a phase angle that is offset from the phase angle of the reactive current generated by a second inverter. As a result, the reactive current from the first inverter cancels at least a portion of the reactive current from the second inverter, reducing the total reactive current present on the DC bus. | 12-11-2014 |
Patent application number | Description | Published |
20080286229 | METHOD TO PROMOTE HAIR GROWTH AND/OR DELAY OR TREAT HAIR LOSS BY ADMINISTERING A TGF-BETA ANTAGONIST OR INHIBITOR - The present invention provides methods for promoting hair growth and/or treating or preventing hair loss (alopecia) by contacting the cells with a TGF-β antagonist or inhibitor either alone or in combination with other alopecia-inhibiting compounds. | 11-20-2008 |
20090062247 | METHODS FOR INHIBITING TGF-beta - The present invention provides methods for inhibiting or blocking TGF-β activity in cells and/or tissues expressing TGF-β comprising, contacting cells and/or tissues expressing TGF-β with an amount of cholesterol or cholesterol derivative effective to inhibit the activity of TGF-β. The present invention further provides a method for treating a condition associated with overactivity of TGF-β or negative regulation in normal physiology by TGF-β in a subject in need of treatment, comprising contacting cells and/or tissue overexpressing TGF-β in the subject with an amount of cholesterol or cholesterol derivative effective to inhibit activity of TGF-β thereby treating the condition. In a preferred embodiment, the cholesterol derivative is oxidized 7-DHC. | 03-05-2009 |
20100075923 | METHOD OF ENHANCING TGF-BETA SIGNALLING - The present invention is directed to a method of enhancing TGF-β signaling in a subject comprising administering to said subject a clathrin-dependent endocytosis inhibitor in an amount sufficient to enhance TGF-β signaling. In another aspect, the invention is directed to a method of treating a condition associated with decreased TGF-β signaling in a patient in need thereof comprising administering to said patient a clathrin-dependent endocytosis inhibitor in a therapeutically effective amount. | 03-25-2010 |
20140271723 | ADJUVANT COMPOSITIONS AND METHODS OF USING THEREOF - The present invention relates to adjuvant compositions, vaccine compositions, and methods of enhancing an immune response to an antigen. | 09-18-2014 |