Patent application number | Description | Published |
20140134205 | COMPOSITIONS, METHODS AND USES FOR DENGUE VIRUS SEROTYPE-4 CONSTRUCTS - Embodiments herein report compositions, methods and uses for dengue-4 (DENV-4) virus constructs. Some embodiments concern a composition that includes, but is not limited to, DENV-4 virus constructs alone or in combination with other constructs, can be used in a vaccine composition to induce an immune response in a subject. In certain embodiments, compositions can include constructs of more than one serotypes of dengue virus, such as dengue-1 virus, dengue-2 virus, or dengue-3 virus in combination with DENV-4 virus constructs disclosed herein. In other embodiments, DENV-4 constructs disclosed herein can be combined in a composition with other flavivirus constructs to generate a vaccine against more than one flavivirus. Other embodiments provide methods and uses for DENV-4 virus constructs in vaccine compositions that when administered to a subject induce an immune response in the subject against DENV-4 that is improved by modified constructs compared to other vaccine compositions. | 05-15-2014 |
20140302088 | COMPOSITIONS AND METHODS FOR DENGUE VIRUS CHIMERIC CONSTRUCTS IN VACCINES - Embodiments herein report compositions, uses and manufacturing of dengue virus constructs and live attenuated dengue viruses. Some embodiments concern a composition that includes, but is not limited to, a tetravalent dengue virus composition. In certain embodiments, compositions can include constructs of one or more serotypes of dengue virus, such as dengue-1 (DEN-1) virus, dengue-2 (DEN-2) virus, dengue-3 (DEN-3) or dengue-4 (DEN-4) virus constructs. In other embodiments, constructs disclosed herein can be combined in a composition to generate a vaccine against more one or more dengue virus constructs that may or may not be subsequently passaged in mammalian cells. | 10-09-2014 |
Patent application number | Description | Published |
20100159602 | CARBON MEASUREMENT IN AQUEOUS SAMPLES USING OXIDATION AT ELEVATED TEMPERATURES AND PRESSURES - Apparatus and methods for measuring the concentrations of organic and inorganic carbon, or of other materials, in aqueous samples are described, together with related, specially adapted components and sub-assemblies and related control, operational and monitoring systems. | 06-24-2010 |
20110155270 | Carbon measurement in aqueous samples using oxidation at elevated temperatures and pressures - Apparatus and methods for measuring the concentrations of organic and inorganic carbon, or of other materials, in aqueous samples are described, together with related, specially adapted components and sub-assemblies and related control, operational and monitoring systems. | 06-30-2011 |
20110155272 | Carbon measurement in aqueous samples using oxidation a elevated temperatures and pressures - Apparatus and methods for measuring the concentrations of organic and inorganic carbon, or of other materials, in aqueous samples are described, together with related, specially adapted components and sub-assemblies and related control, operational and monitoring systems. | 06-30-2011 |
20110155912 | Carbon measurement in aqueous samples using oxidation at elevated temperatures and pressures - Apparatus and methods for measuring the concentrations of organic and inorganic carbon, or of other materials, in aqueous samples are described, together with related, specially adapted components and sub-assemblies and related control, operational and monitoring systems. | 06-30-2011 |
20110163463 | Carbon measurement in aqueous samples using oxidation at elevated temperatures and pressures - Apparatus and methods for measuring the concentrations of organic and inorganic carbon, or of other materials, in aqueous samples are described, together with related, specially adapted components and sub-assemblies and related control, operational and monitoring systems. | 07-07-2011 |
20110300492 | Method and Apparatus for Monitoring Combustion Properties in an Interior of a Boiler - A method of monitoring combustion properties in an interior of a boiler of the type having walls comprising a plurality of parallel steam tubes separated by a metal membrane. First and second penetrations are provided in the metal membrane between adjacent tubes on opposite sides of the boiler. A beam of light is projected through a pitch optic comprising a pitch collimating lens and a pitch relay lens, both residing outside the boiler interior. The pitch relay lens projects the beam through a penetration into the boiler interior. The beam of light is received with a catch optic substantially identical to the pitch optic residing outside the boiler interior. The strength of the collimated received beam of light is determined. At least one of the pitch collimating lens and the catch collimating lens may then be aligned to maximize the strength of the collimated received beam. | 12-08-2011 |
Patent application number | Description | Published |
20140275826 | PHOTOACOUSTIC SENSORS FOR PATIENT MONITORING - Various methods and systems for photoacoustic patient monitoring are provided. A photoacoustic system includes a light emitting component that emits one or more wavelengths of light into an interrogation region of a patient and an acoustic detector that detects acoustic energy generated by the interrogation region of the patient in response to the emitted light. A reflective coating is disposed on the light emitting component, the acoustic detector, the patient, or a combination thereof to direct the emitted light toward the interrogation region of the patient. | 09-18-2014 |
20140275941 | PHOTOACOUSTIC MONITORING TECHNIQUE WITH NOISE REDUCTION - Various methods and systems for photoacoustic patient monitoring are provided. A photoacoustic system includes a light emitting component that emits one or more wavelengths of light into an interrogation region of a patient and an acoustic detector that detects acoustic energy generated by the interrogation region of the patient in response to the emitted light. The system also includes an optical detector that detects the emitted light and provides a signal that is used as an input to remove noise from the signal generated by the acoustic detector. | 09-18-2014 |
20140275943 | PHOTOACOUSTIC MONITORING TECHNIQUE - Various methods and systems for photoacoustic patient monitoring are provided. A photoacoustic system includes a light emitting component that emits one or more wavelengths of light into an interrogation region of a patient and an acoustic detector that detects acoustic energy generated by the interrogation region of the patient in response to the emitted light. The system may be implemented to receive photoacoustic waves from a local vein and artery and determine hemodynamic parameters based on a summed indicator dilution curve representative of both arterial and venous indicator dilution. | 09-18-2014 |
20150051473 | SYSTEMS AND METHODS FOR PHOTOACOUSTIC SPECTROSCOPY - A photoacoustic sensor system includes a photoacoustic sensor assembly having a light emitting component configured to emit one or more wavelengths of light into a region of a patient's tissue and an acoustic detector configured to detect acoustic energy generated within the region of the patient's tissue in response to the emitted light. The photoacoustic sensor assembly is configured to generate a signal that enables a monitor to determine a potion of the sensor assembly relative to the patient's tissue. | 02-19-2015 |
20150065956 | SYSTEMS AND METHODS FOR MONITORING AN INJECTION PROCEDURE - An indicator dilution system includes a catheter configured to deliver an indicator to a patient, an injection device configured to deliver the indicator to the catheter, and a connector coupling the injection device to the catheter. The system also includes one or more sensors configured to acquire measurements from components of the system, which may be used to determine the start and end time of the injection of the indicator to the patient. For example, the one or more sensors may be configured to acquire signals relating to a state of the connector, which may be used to determine whether the connector is in an open state to enable flow of the indicator or in a closed state to reduce flow of the indicator. | 03-05-2015 |
20150208924 | PHOTOACOUSTIC SENSORS WITH DIFFUSING ELEMENTS FOR PATIENT MONITORING - Various methods and systems for photoacoustic patient monitoring are provided. A photoacoustic system includes a sensor having a body and one or more light emitting components disposed in the body that emit one or more wavelengths of light. A light guide receives the one or more wavelengths of light and guides the one or more wavelengths of light into an interrogation region of a patient. A wide angle diffusing element is disposed on a tip of the light guide and has a diffusing angle of greater than or equal to 80 degrees. The wide angle diffusing element diffuses the one or more wavelengths of light when the sensor is opposed by air. One or more acoustic detectors are disposed in the body and detect acoustic energy generated by the interrogation region of the patient in response to the emitted light when the sensor is opposed by the patient. | 07-30-2015 |
Patent application number | Description | Published |
20100208244 | FLASH LADAR SYSTEM - The present invention pertains in general to a single, integrated flash LADAR system and method. The system includes data processing hardware and software, a passive two-dimensional camera, a three-dimensional camera, a light source, and a common optical path. One or more star trackers can also be included. In addition, auxiliary components, such as an inertial measurement unit and a global positioning system receiver can be included. The system can be closely integrated with a critical algorithm suite that operates in multiple modes, in real-time to enable landing, docking, and navigation functions, such as Guidance, Navigation, and Control (GNC), Altimetry, Velocimetry, Terrain Relative Navigation (TRN), Hazard Detection and Avoidance (HDA), and dust penetration. | 08-19-2010 |