Hope
Hope Agbemenyah, Goettingen DE
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20130028956 | METHOD FOR PREVENTING OR TREATING MEMORY IMPAIRMENT AND PHARMACEUTICAL COMPOSITIONS USEFUL THEREFORE - In a first aspect, the present invention relates to a method for prevention or treating memory impairment and/or a neurodegenerative condition, disorder or disease in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound targeting a miRNA or any precursor, or targeting the activity of said miRNA or any precursor thereof. In particular, the present invention relates to a method wherein the targeted miRNA is miR-34. Moreover, the present invention relates to a method for improving memory functionality in a subject suffering from memory loss, said method comprises the reduction or reducing the level of miR-34 levels or precursor molecule levels in brain tissue of said subject administering to the subject a therapeutically effective amount of a compound targeting miR-34 or any precursor thereof. | 01-31-2013 |
Hope Foudoulakis, Framingham, MA US
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20100144707 | Pharmacokinetically improved compounds - The present invention relates to inhibitors of ROCK1 and ROCK2 and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and or ROCK2 that are useful for the treatment of disease. | 06-10-2010 |
20120202793 | RHO KINASE INHIBITORS - The present invention relates to inhibitors of ROCK1 and ROCK2, which may be selective for ROCK2, and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and/or ROCK2. Also provided are treatments combining inhibitors of ROCK1 and/or ROCK2 with statins. | 08-09-2012 |
20130131047 | PHARMACOKINETICALLY IMPROVED COMPOUNDS - The present invention relates to inhibitors of ROCK1 and ROCK2 and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and or ROCK2 that are useful for the treatment of disease. | 05-23-2013 |
Hope Gurion, Winnetka, IL US
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20120095931 | Contact Referral System and Method - A recruiting tool for leveraging social and business contacts of existing employees, contractors, franchisees and the like is disclosed. The system provides an application for evaluating contact data of employee contacts available through existing social networks or other applications. The application compares the contact data to opportunity description data and, if any of the contacts appear to possess the proper qualifications, matches those contacts to the opportunity of the employer. Feedback is provided to the employee identifying these matched contacts. The employee may then use the application to alert the matched contact of the opportunity, and to submit a referral to the employer relating to the matched contact. Additional system features and options for parties in the role of the employer, the employee, and the matched contacts are disclosed. | 04-19-2012 |
Hope Jackson, Washington, DC US
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20150225784 | COMPOSITIONS AND METHODS FOR DETERMINING THE LIKELIHOOD OF APPENDICITIS - A method for determining a likelihood of appendicitis in a subject is disclosed. The method comprises the steps of (a) determining the relative abundance of microorganisms corresponding to one or more operational taxonomic units (OTUs) in a test biological sample obtained from the subject; (b) comparing the relative abundance of the microorganisms in each of the one or more OTUs to a corresponding reference value assigned to each of the one or more OTUs, and (c) determining a likelihood of appendicitis in the subject based on the result in step (b), wherein a significant increase in relative abundance of the microorganisms in the one or more OTUs indicates a high risk of appendicitis in the subject. Also disclosed is a kit for determining a likelihood of appendicitis in a subject. | 08-13-2015 |
Hope Lancero, Palo Alto, CA US
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20080262092 | REGULATION OF OSTEOPONTIN - The present invention provides methods for the regulation of osteopontin activity in a subject as well as for treating or preventing conditions associated with an increased activity of osteopontin activity in a subject. | 10-23-2008 |
20130317113 | REGULATION OF OSTEOPONTIN - The present invention provides methods for the regulation of osteopontin activity in a subject as well as for treating or preventing conditions associated with an increased activity of osteopontin activity in a subject. | 11-28-2013 |
Hope Matis, Schenectady, NY US
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20090308812 | METHODS AND SYSTEM FOR REMOVING IMPURITIES FROM HEAVY FUEL - A method of removing impurities from heavy fuel includes providing a first stationary adsorption column. The method further includes packing adsorbent particles that have a particle size distribution wherein at least about 50% of the particles have a diameter greater than about 18 microns in the first column. The method further includes diluting heavy fuel with a solvent to form a solvent-fuel mixture, and supplying the solvent-fuel mixture through the first column to facilitate removing impurities from the mixture. | 12-17-2009 |
20120097614 | NORM REMOVAL FROM FRAC WATER - A method for treating low barium frac water includes contacting a frac water stream with a radium selective complexing resin to produce a low radium stream, passing the low radium stream through a thermal brine concentrator to produce a concentrated brine; and passing the concentrated brine through a thermal crystallizer to yield road salt. | 04-26-2012 |
20130134098 | WATER TREATMENT PROCESSES FOR NORM REMOVAL - Methods for treating water to remove radium include contacting the water with a magnetic adsorbent comprising manganese oxide(s), and applying a magnetic field to separate the magnetic adsorbent from the water, whereby radium is removed from the water. The methods may additionally include regenerating the magnetic adsorbent, and contacting the water with regenerated magnetic adsorbent. Alternately, calcium and/or strontium may be precipitated as carbonate salts from lime-treated water containing radium and barium without precipitating a significant fraction of the barium or radium; and removing radium from calcium- and strontium-free water by precipitating the barium and radium as carbonate salts. The barium- and radium carbonate precipitate may be redissolved in hydrochloric acid and disposed of by deep-well injection. | 05-30-2013 |
Hope Queener, Houston, TX US
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20130100405 | WAVEFRONT SENSORLESS ADAPTIVE CORRECTION OF THE WAVE ABERRATION FOR AN EYE - Embodiments of the invention generally provide apparatuses and methods utilized in optics, and more specifically to apparatuses and methods for adaptive optics correction and imaging. Real-time wavefront sensorless adaptive optics correction and imaging is used with the living human eye to produce optical quality rivaling that of wavefront sensor based control in the similar systems. Using an optimization algorithm that is based on an image quality metric, the apparatus and method optimize the optical quality in ocular image frames acquired with an adaptive optics system. | 04-25-2013 |
Hope Stale, Vestskogen NO
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20100026234 | APPARATUS FOR OPERATING CONTROLLABLE INSTALLATION MEANS - An apparatus for power supply to electronic, electrical or electromechanical equipment, the apparatus including a chargeable power source in the form of at least one high energy capacitor package ( | 02-04-2010 |