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| 20120038255 | EJECTION DEVICE FOR A MOVABLE FURNITURE PART - The invention relates to an arrangement for locking and ejecting a movable furniture part, comprising two unlockable ejection devices arranged on both sides of a furniture body or on the movable furniture part, and spring-loaded ejectors, wherein the unlockable ejection devices comprise a catch element mounted on a linearly displaceable carriage, the catch element engaging into a slotted guide path having the shape of a heart curve and by which the movable furniture part can be held in a closed latching position (E) via a locking element. According to the invention, this latching position (E) can be released by overpressing the movable furniture part towards the interior, wherein the linearly displaceable carriages of the two unlockable ejector devices are motionally coupled via a rotatable synchronization rod. | 02-16-2012 |
| 20120292465 | COUPLING DEVICE HAVING SIDE ADJUSTMENT FOR A DRAWER - The invention relates to a device for detachably coupling a drawer to an extendable rail of a pullout guide, comprising an adjusting apparatus by means of which a position of a drawer connected to the rail can be adjusted in the lateral direction relative to the rail, wherein the device ( | 11-22-2012 |
| 20130293077 | COUPLING DEVICE FOR DRAWERS - The invention relates to a device ( | 11-07-2013 |
| 20130293078 | ADJUSTMENT DEVICE FOR DRAWER FACEPLATES - The invention relates to a device for detachably coupling a drawer to an extendable rail of a pull-out guide, having an adjusting device by which a position of a drawer connected to the rail is adjustable relative to the rail in a lateral direction, wherein the device comprises a fastening part that can be fastened to the drawer and a coupling part that can be coupled to the rail. The fastening part is linearly movable by the adjusting device relative to the coupling part and the adjustment device comprises a setting wheel mounted on the coupling part or on the fastening part so as to rotate about an axis, wherein the adjustment device comprises at least two axially spaced devices for converting a rotary movement of the setting wheel into a linear movement of the fastening part relative to the coupling part. | 11-07-2013 |
| 20130334946 | EJECTION DEVICE FOR A MOVABLE FURNITURE PART - Locking and ejecting a movable furniture part involves two unlockable ejection devices arranged on both sides of a furniture body, or on the movable furniture part, and spring-loaded ejectors the unlockable ejection devices comprise a catch element mounted on a linearly displaceable carriage, the catch element engaging into a slotted guide path having the shape of a heart curve and by which the movable furniture part can be held in a closed latching position (E) via a locking element. This latching position (E) can be released by overpressing the movable furniture part towards the interior, wherein the linearly displaceable carriages of the two unlockable ejector devices are motionally coupled via a rotatable synchronization rod. | 12-19-2013 |
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| 20130046275 | MATERIAL AND METHOD FOR TREATING INTERNAL CAVITIES - A hydrophilic biocompatible sustained-release material is disclosed. The material comprises amounts of Pluronic F-127, PEG-400, HPMC and water, effective to produce a composition of sufficiently low viscosity at room temperature to be injectable into an internal body cavity via a tube inserted within a urinary catheter. At body temperature, the material exhibits a much higher viscosity and will stably adhere to the internal surface of a body cavity. As the material dissolves, a therapeutic agent incorporated therein is slowly released to the body cavity, while the material itself is excreted from the body. | 02-21-2013 |
| 20130274858 | STENT WITH SHEATH AND METAL WIRE RETAINER - A stent assembly ( | 10-17-2013 |
| 20140309723 | STENT WITH SHEATH AND METAL WIRE - A stent assembly includes a stent and a fiber mesh sleeve covering the stent. A wire runs along the stent over the sleeve and fastened to the stent at multiple points so as to attach the sleeve to the stent. | 10-16-2014 |
| 20140309725 | OPTIMIZED DRUG-ELUTING STENT ASSEMBLY - A stent assembly including a stent configured to be positioned in a body lumen, and a knitted stent jacket including an expansible mesh structure having a coverage area of less than 25%, having approximate aperture diameters greater than 20 micrometers, and surrounding an external surface of the stent and coaxially associated therewith, wherein the stent assembly elutes an amount of an active pharmaceutical agent. | 10-16-2014 |
| 20150119971 | STENT-MESH ASSEMBLY AND METHODS - A method of affixing a stent jacket to a stent, comprising aligning the stent jacket coaxially with the stent, placing a portion of the stent within a portion of the stent jacket, wherein a central axis of the stent is aligned with a central axis of the stent jacket, and affixing the stent jacket to the stent with a plurality of stitches, wherein the plurality of stitches form a plurality of consecutive loops that pass through one or more holes in the stent jacket and through an outer surface of the stent. | 04-30-2015 |
| 20150246209 | Guide for intravascular device - A device guide ( | 09-03-2015 |
| 20150343233 | METHOD AND APPARATUS FOR TREATING CARDIAC ARRHYTHMIAS USING ELECTROMAGNETIC RESYNCHRONIZATION - A method and an apparatus for the treatment of cardiac arrhythmias using a weak pulsed magnetic field. A transducer that emits electromagnetic radiation of a prescribed frequency and peak intensity is placed on the patient's chest and, as a result, the weak electromagnetic field can cause activation, reactivation, inhibition or remodeling of electrophysiological change in cardiac tissue in an irradiated heart. This treatment method has wide application for use in patients who experience cardiac arrhythmia. | 12-03-2015 |
| 20150366974 | MATERIAL AND METHOD FOR TREATING INTERNAL CAVITIES - A hydrophilic biocompatible sustained-release material is disclosed. The material comprises amounts of Pluronic F-127, PEG-400, HPMC and water, effective to produce a composition of sufficiently low viscosity at room temperature to be injectable into an internal body cavity via a tube inserted within a urinary catheter. At body temperature, the material exhibits a much higher viscosity and will stably adhere to the internal surface of a body cavity. As the material dissolves, a therapeutic agent incorporated therein is slowly released to the body cavity, while the material itself is excreted from the body. | 12-24-2015 |
| 20150374519 | OPTIMIZED DRUG-ELUTING STENT ASSEMBLY - Methods of preparing and using a stent assembly that includes a stent jacket formed from an expansible mesh structure having apertures and that includes a fiber having a diameter of about 7 micrometers and about 40 micrometers, and an expansible stent operatively associated with the stent jacket. The method further comprises administering to the subject an active pharmaceutical ingredient (API) eluted from the stent assembly. | 12-31-2015 |
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| 20100204772 | Filter Assemblies - Disclosed is a filter assembly, comprising: a radially expandable vascular flow-increasing device, and a filter including an expandable proximal opening having an operative connection with the radially expandable vascular flow-increasing device, the proximal opening configured to expand in conjunction with expansion of the device, such that when the opening is in an expanded configuration, the filter is configured to filter debris from a fluid stream in which the filter is disposed. | 08-12-2010 |
| 20100241214 | OPTIMIZED STENT JACKET - A method of stenting, comprises: implanting a stent assembly in a vessel of a subject, the stent assembly, including: a stent jacket, comprising an expansible mesh structure, formed of fibers of a diameter between about 7 micrometers and about 18 micrometers, the diameter having a property of forming a substantially stable layer of endothelial cells, covering the fibers, thus reducing platelet aggregation, and an expansible stent, operatively associated with the stent jacket. The method further comprises administering to the subject an active pharmaceutical ingredient (API) comprising a platelet aggregation reducer for a shortened time period, not exceeding six months, the shortened time period being a consequence of the property. In accordance with some embodiments, the administration of a platelet aggregation. | 09-23-2010 |
| 20100324651 | Knitted Stent Jackets - Disclosed is an assembly for opening a vessel lumen comprising a radially expandable stent configured to open a vessel lumen, the radially expandable stent comprises a curved wall having a proximal portion, a distal portion and a lumen connecting the proximal portion and the distal portion. The assembly further comprises a knitted jacket comprising a plurality of interconnected loops, the knitted jacket further comprising a tubular wall that substantially surrounds an exterior surface of the radially expandable stent, and at least one retainer belt that slidingly passes through at least one knitted loop of the plurality of interconnected loops in the knitted jacket. | 12-23-2010 |
| 20100324664 | Bifurcated Stent Assemblies - Disclosed is a stent assembly for expanding in vivo vessels, the assembly comprises: two stents, a first stent and a second stent, the two stents positioned so that a forward end of the first stent is separated by a predetermined distance from a rearward end of the second stent, and a stent jacket spanning the predetermined distance such that a first end of the jacket is operatively associated with the first stent and a second end of the jacket is operatively associated with the second stent. | 12-23-2010 |
| 20120010649 | IN VIVO FILTER ASSEMBLY - Disclosed is an assembly for filtering debris flowing in an in vivo fluid stream, the assembly comprising at least one balloon configured to volumetrically expand and, during at least a portion of the expansion, operatively connect with a filter, and to contract following the expansion. The assembly further comprising a filter configured to operatively connect with the at least one balloon during at least a portion of the volumetric expansion of the at least one balloon, such that the filter expands during the operative connection in order to filter debris from a fluid flowing in a fluid stream within which the expanded filter is disposed. | 01-12-2012 |
| 20120215097 | INJECTION CATHETER WITH NEEDLE ELECTRODE - An injection catheter for infusing therapeutic and diagnostic agents into the heart comprises a catheter body and a tip section mounted at the distal end of the catheter body. A needle control handle is provided at the proximal end of the catheter body. An injection needle extends through the tip section, catheter body, and needle control handle. The injection needle is longitudinally slidable within the tip section so that its distal end can extend beyond the distal end of the tip section upon suitable manipulation of the needle control handle. The catheter further comprises an electrode lead wire having a first end electrically connected to the injection needle and a second end electrically connected to a suitable monitoring apparatus or to a source of ablation energy. The injection needle can thus be used for mapping or ablation in addition to introducing therapeutic and diagnostic agents into the heart. | 08-23-2012 |
| 20130110030 | METHOD FOR PRODUCING SEVERAL INJECTION-MOLDED PARTS | 05-02-2013 |
| 20130110031 | BIOCOMPATIBLE DRUG DELIVERY APPARATUS AND METHODS | 05-02-2013 |
| 20150209300 | METHODS FOR TREATMENT OF BLADDER CANCER - Apparatus and methods for treatment of an internal cavity are provided. The internal cavity is coated with a treatment solution. The treatment solution can include a solidifiable matrix with or without a drug or combination of drugs incorporated therein, or a drug solution without a solidifiable matrix. The treatment solution is coated onto at least a portion of the internal cavity, and acts as a slow-release drug delivery system. | 07-30-2015 |
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| 20090209736 | MULTICOLUMN SEQUENTIAL SEPARATION PROCESS - The subject of the invention is separation on a solid support by multi-column sequential selective retention in order to separate a product of interest from a solution containing such a product of interest, by passing this solution over a fixed chromatographic resin bed comprising at least three zones, liquid flow means being placed between adjacent zones and between the last zone and the first zone, this process comprising several sequences, each sequence comprising at least one step chosen from an absorption step, a rinsing step and a desorption step, carried out either simultaneously or not, each following sequence is carried out by the displacement of the fronts in the zones towards the downstream end substantially of the same increment before the periodic displacement of the points of introduction and of withdrawal, characterized in that the process includes a sub-sequence without injection of the charge. | 08-20-2009 |
| 20120214966 | MULTICOLUMN SEQUENTIAL SEPARATION PROCESS - A process is disclosed for separating biomolecules from an aqueous solution containing the biomolecules and impurities, having different affinities and/or interactions with a solid support. The solution is passed over a fixed bed of chromatographic resin containing at least three zones, with flow of liquid being arranged between adjacent zones and between a last and first zone. Each of several sequences includes at least an adsorption stage, a rinsing stage, or a desorption stage, with each subsequent sequence being carried out by a downstream displacement of fronts in the zones by approximately the same increment before the periodical displacement of the introduction and withdrawal points. | 08-23-2012 |
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| 20110021520 | OXAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS - The invention relates to novel heterocyclic compounds of the formula | 01-27-2011 |
| 20120172359 | Oxazine Derivatives and their Use in the Treatment of Neurological Disorders - The invention relates to novel heterocyclic compounds of the formula | 07-05-2012 |
| 20120238560 | Oxazine Derivatives and their Use in the Treatment of Neurological Disorders - The invention relates to novel heterocyclic compounds of the formula | 09-20-2012 |
| 20130281473 | SUBSTITUTED ISOQUINOLINONES AND QUINAZOLINONES - The invention relates to substituted nitrogen containing bicyclic heterocycles of the formula (I) | 10-24-2013 |
| 20130317024 | PYRROLOPYRROLIDINONE COMPOUNDS - The invention relates to compounds of formula (I): | 11-28-2013 |
| 20140088084 | OXAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS - The invention relates to novel heterocyclic compounds of the formula | 03-27-2014 |
| 20140113894 | OXAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS - The invention relates to novel heterocyclic compounds of the formula | 04-24-2014 |
| 20140135306 | HDYROXY SUBSTITUTED ISOQUINOLINONE DERIVATIVES - The invention relates to compounds of formula (I): as defined in the application. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof. | 05-15-2014 |
| 20140275158 | CYCLOHEXYL ISOQUINOLINONE COMPOUNDS - The invention relates to compounds of formula (I): as defined in the application. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof. | 09-18-2014 |
| 20140343084 | IMIDAZOPYRROLIDINONE COMPOUNDS - The invention relates to compounds of formula (I): | 11-20-2014 |
| 20140350010 | Pyrazolopyrrolidine Compounds - The invention relates to compounds of formula (I) as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of MDM2 and/or MDM4, and combinations comprising such compounds. | 11-27-2014 |
| 20150353551 | SUBSTITUTED PURINONE COMPOUNDS - The invention relates to compounds of formula (I): (I) as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of as MDM2 and/or MDM4, and combinations comprising such compounds. | 12-10-2015 |
| 20150353563 | PYRAZOLO[3,4-D]PYRIMIDINONE COMPOUNDS AS INHIBITORS OF THE P53/MDM2 INTERACTION - The invention relates to compounds of formula (I): as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of MDM2 and/or MDM4, and combinations comprising such compounds. | 12-10-2015 |
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| 20120025342 | INTEGRATED CIRCUIT COMBINATION OF A TARGET INTEGRATED CIRCUIT AND A PLURALITY OF CELLS CONNECTED THERETO USING THE TOP CONDUCTIVE LAYER - A target integrated circuit (TIC) having a top conductive layer (TCL) that may be connected to a plurality of cells that are further integrated over the TIC. Each of the plurality of cells comprises two conductive layers, a lower conductive layer (LCL) below the cell and an upper conductive layer (UCL) above the cell. Both conductive layers may connect to the TCL of the TIC to form a super IC structure combined of the TIC and the plurality of cells connected thereto. Accordingly, conductivity between the TIC as well as auxiliary circuitry to the TIC maybe achieved. | 02-02-2012 |
| 20120085385 | INTEGRATED CIRCUIT COMBINATION OF A TARGET INTEGRATED CIRCUIT AND A PLURALITY OF PHOTOVOLTAIC CELLS CONNECTED THERETO USING THE TOP CONDUCTIVE LAYER - An integrated circuit (IC) combination of a target integrated circuit (TIC) and a plurality of thin film photovoltaic cells (PV) connected thereto. The IC comprises a target integrated circuit (TIC) having a top surface and a bottom surface; a plurality of thin film photovoltaic (PV) cells formed over at least one of the top surface and the bottom surface of the TIC, each PV cell includes at least a lower conducting layer (LCL) and an upper conducting layer (UCL); and a conducting path connecting at least a UCL of a first PV cell to at least a LCL of a second PV cell, wherein at least a first array of PV cells comprised of at least a first portion of the plurality of PV cells is connected by the respective UCL and LCL of each PV cell to provide a first voltage output. | 04-12-2012 |
| 20130264870 | INTEGRATED CIRCUIT ENERGY HARVESTER - A system for energy harvesting comprises a first interface for receiving energy from at least one renewable energy source (ERS); a second interface coupled to at least one load circuit; a third interface coupled to an least one primary energy storage (PES); a DC-to-DC converter connected to one of a single inductor and a single capacitor; a switching circuitry connected to the first, second, and third interfaces and the DC-to-DC converter; a control unit connected to the DC-to-DC converter and the switching circuitry, the control unit controls the system to operate in an operation mode including any one of: provide energy from the ERS to the at least one load via the DC-to-DC converter, charge the least one PES from the at least one ERS via the DC-to-DC converter, and provide energy from the at least one PES to the at least one load circuit via the DC-to-DC converter. | 10-10-2013 |
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| 20090138070 | Stent Apparatuses for Treatment Via Body Lumens and Methods of Use - An enhanced stent apparatus, comprising: a support element, wherein the support element is constructed to be positioned in a body lumen; and, a porous structure, the porous structure located on a surface of the support element, and wherein the porous structure is comprised of at least one fiber under 30 microns in diameter, has a coverage area of less than 30% and is provided with apertures. | 05-28-2009 |
| 20150032197 | CAROTID STENT ASSEMBLY AND METHODS FOR TREATMENT VIA BODY LUMENS - A stent assembly adapted to carotid arterial placement that includes a self-expanding support element comprising metal struts constructed to be positioned in a body lumen and expanded from a retracted state to an expanded state, and a knitted cover disposed over an exterior of the support element and along an entire length thereof, wherein the knitted cover comprises a single polymer fiber having a diameter of at least 40 nanometers to 30 microns, wherein the self-expanding support element and knitted cover together have apertures sized 20 microns to smaller than 100 microns in diameter to block larger debris when the stent assembly is placed in a carotid artery and expanded to the expanded state. Methods of stenting a carotid artery by applying the stent assembly to the carotid artery of a patient in need of treatment and expanding the stent assembly in situ are disclosed. | 01-29-2015 |
| 20150230953 | STENT WITH SHEATH AND METAL WIRE AND METHODS - A stent assembly includes a stent and a fiber mesh sleeve covering the stent. A wire runs along the stent over the sleeve and fastened to the stent at multiple points so as to attach the sleeve to the stent. Methods of making the stent assembly are included. | 08-20-2015 |
