Hock
Christoph Hock, Erlenbach CH
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20100202968 | Method of Providing Disease-Specific Binding Molecules and Targets - Provided are novel specific binding molecules, particularly human antibodies as well as fragments, derivatives and variants thereof that recognize neoepitopes of disease-associated proteins which derive from native endogenous proteins but are prevalent in the body of a patient in a variant form and/or out of their normal physiological context. In addition, pharmaceutical compositions comprising such binding molecules, antibodies and mimics thereof and methods of screening for novel binding molecules, which may or may not be antibodies as well as targets in the treatment of neurological disorders such as Alzheimer's disease are described. | 08-12-2010 |
20110300077 | Human Anti-Alpha-Synuclein Antibodies - Provided are human alpha-synuclein-specific autoantibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for α-synuclein are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for α-synuclein targeted immunotherapy and diagnosis, respectively. | 12-08-2011 |
20120087861 | Human Anti-Tau Antibodies - Provided are novel human tau-specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for tau are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for tau targeted immunotherapy and diagnosis, respectively. | 04-12-2012 |
20130216555 | METHOD OF PROVIDING DISEASE-SPECIFIC BINDING MOLECULES AND TARGETS - Provided are novel specific binding molecules, particularly human antibodies as well as fragments, derivatives and variants thereof that recognize neoepitopes of disease-associated proteins which derive from native endogenous proteins but are prevalent in the body of a patient in a variant form and/or out of their normal physiological context. In addition, pharmaceutical compositions comprising such binding molecules, antibodies and mimics thereof and methods of screening for novel binding molecules, which may or may not be antibodies as well as targets in the treatment of neurological disorders such as Alzheimer's disease are described. | 08-22-2013 |
20130266514 | Method of Providing Disease-Specific Binding Molecules and Targets - Provided are novel specific binding molecules, particularly human antibodies as well as fragments, derivatives and variants thereof that recognize neoepitopes of disease-associated proteins which derive from native endogenous proteins but are prevalent in the body of a patient in a variant form and/or out of their normal physiological context. In addition, pharmaceutical compositions comprising such binding molecules, antibodies and mimics thereof and methods of screening for novel binding molecules, which may or may not be antibodies as well as targets in the treatment of neurological disorders such as Alzheimer's disease are described. | 10-10-2013 |
20130266585 | Method of Providing Disease-Specific Binding Molecules and Targets - Provided are novel specific binding molecules, particularly human antibodies as well as fragments, derivatives and variants thereof that recognize neoepitopes of disease-associated proteins which derive from native endogenous proteins but are prevalent in the body of a patient in a variant form and/or out of their normal physiological context. In addition, pharmaceutical compositions comprising such binding molecules, antibodies and mimics thereof and methods of screening for novel binding molecules, which may or may not be antibodies as well as targets in the treatment of neurological disorders such as Alzheimer's disease are described. | 10-10-2013 |
20130266586 | Method of Providing Disease-Specific Binding Molecules and Targets - Provided are novel specific binding molecules, particularly human antibodies as well as fragments, derivatives and variants thereof that recognize neoepitopes of disease-associated proteins which derive from native endogenous proteins but are prevalent in the body of a patient in a variant form and/or out of their normal physiological context. In addition, pharmaceutical compositions comprising such binding molecules, antibodies and mimics thereof and methods of screening for novel binding molecules, which may or may not be antibodies as well as targets in the treatment of neurological disorders such as Alzheimer's disease are described. | 10-10-2013 |
20130295021 | HUMAN ANTI-TAU ANTIBODIES - Provided are human tau-specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for tau are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for tau targeted immunotherapy and diagnosis, respectively. | 11-07-2013 |
20140044644 | ANKYRIN G AND MODULATORS THEREOF FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS - The present invention generally relates to the technical field of medicine, in particular to the field of neurodegenerative, neurological and protein misfolding disorders such as amyloidosis. By establishing a role of ankG in APP processing the method of the present invention provides a new insight into the role of ankG in AD pathology and provides ankG as a target, drug, diagnostic agent and particularly as a vaccine in the treatment and diagnosis of the pathogenesis of Alzheimer's disease (AD). | 02-13-2014 |
20140255304 | TDP-43 SPECIFIC BINDING MOLECULES - Provided are novel TDP-43-specific binding molecules including polypeptides such as human antibodies, as well as fragments, derivatives and variants thereof. Also provided are methods related to these TDP-43 specific binding molecules. Assays, kits, and solid supports related to TDP-43-specific binding molecules, including polypeptides such as, human antibodies are also disclosed. The TDP-43-specific binding molecule, antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for TDP-43 targeted immunotherapy and diagnosis, respectively. | 09-11-2014 |
20140301945 | HUMAN ANTI-SOD1 ANTIBODIES - Provided are novel human copper-zinc superoxide dismutase, also known as superoxide dismutase 1 or SOD1, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for SOD1 are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for SOD1 targeted immunotherapy and diagnosis, respectively. | 10-09-2014 |
Cristoph Hock, Erlenbach CH
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20140369940 | Anti-Alpha Synuclein Binding Molecules - Provided are anti-human α-synuclein-specific binding molecules, e.g., antibodies or antigen-binding fragments, variants or derivatives thereof, as methods related thereto. Further provided are anti-human α-synuclein binding molecules which bind to specific N-terminal and C-terminal epitopes on human α-synuclein. The binding molecules described herein can be used in pharmaceutical and diagnostic compositions for α-synuclein targeted immunotherapy and diagnosis, respectively. | 12-18-2014 |
Koh Tuang Hock, Taichung City TW
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20080315645 | Chair capable of being firmly stacked - A chair capable of being firmly stacked comprises a seat; at least one supporting leg being connected to a bottom of the seat, the supporting leg including a resisting section and a wheel assembly; one end of the resisting section being connected to a bottom of the seat and another end of the resisting section being connected to the wheel assembly; the wheel assembly including a connecting block and a wheel pivoted to the connecting block; one inner side of the connecting block being formed with a resisting groove; the wheel being installed at an outer side of the supporting leg and being rotatable with respect to the connecting block; the resisting groove having a shape corresponding to a periphery of the resisting section so that the resisting groove can receive the resisting section of another chair. | 12-25-2008 |
20080315646 | CHAIR CAPABLE OF BEING FIRMLY STACKED - A chair capable of being firmly stacked comprises a seat; at least one supporting leg being connected to a bottom of the seat, the supporting leg including a resisting section and a wheel assembly; one end of the resisting section being connected to a bottom of the seat and another end of the resisting section being connected to the wheel assembly; the wheel assembly including a connecting block and a wheel pivoted to the connecting block; one inner side of the connecting block being formed with a resisting groove; the wheel being installed at an outer side of the supporting leg and being rotatable with respect to the connecting block; the resisting groove having a shape corresponding to a periphery of the resisting section so that the resisting groove can receive the resisting section of another chair. | 12-25-2008 |
20090016008 | CABINET FOR RECEIVING AND CHARGING POWER TO NOTEBOOK COMPUTERS - A cabinet for receiving and charging power to notebook computers comprises a cabinet body; a receiving space formed in the cabinet body; a plurality of drawers arranged longitudinally installed in the receiving space; each door being installed with a plurality of retainers; a power supply portion having a power source and at least one receptacle which is connected to the power source; the power source being connected externally to other power supply; a transformer receiving portion formed at a backside of each door being formed as a receiving space; and a control portion connected to the power supply portion for turning off the power unit at a setting time. Each retainer has an approximate V shape for receiving at least one notebook computer. | 01-15-2009 |
Lim Kian Hock, Singapore SG
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20110049708 | Semiconductor Chip Interconnection Structure and Semiconductor Package Formed Using the Same - A semiconductor chip interconnection structure and a semiconductor package formed using the same are provided. The semiconductor chip interconnection structure comprises a chip, a bump assembly and an electrical element. The chip comprises a pad and has a pad aperture from which the pad is exposed. The bump assembly comprises a first bump and a second bump. The first bump is disposed on the pad. The second bump is disposed on the first bump. The outer diameter of the second bump is not less than the outer diameter of the first bump. The electrical element is connected to the bump assembly. | 03-03-2011 |
Tee Boon Hock, Singapore SG
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20100302607 | IMAGE READING APPARATUS AND IMAGE READING METHOD - An image reading apparatus that optically reads a document includes: multiple line sensors provided approximately parallel to each other and each having light-receiving elements arranged in line form, each line sensor capturing respective line-shaped regions spanning in the main scanning direction of the document in respective color components; a movement unit that causes the positional relationship between the document and the multiple line sensors to move relative to the sub scanning direction that is orthogonal to the main scanning direction; a color skew adjustment unit that adjusts positional skew in the sub scanning direction in scan data of each of the color components captured by the multiple line sensors in synchronization with the movement caused by the movement unit, in accordance with an offset amount based on the distance between each of the multiple line sensors. | 12-02-2010 |
Teo Boon Hock, Taoyuan County TW
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20110102364 | CAPACITIVE TOUCH PANEL - A capacitive touch panel is provided. The capacitive touch panel includes a transparent substrate, a plurality of first sensing wires, a plurality of second sensing units, an insulation layer, a plurality of second sensing wires and a plurality of fourth sensing units. The transparent substrate has a substrate surface on which the insulation layer is disposed. The insulation layer covers the first sensing wires and the second sensing wires. A plurality of third sensing units of the second sensing wires is disposed on the insulation layer along a second axial direction. The fourth sensing units are disposed on the insulation layer along a first axial direction. The third sensing units and the fourth sensing units are adjacently arranged. | 05-05-2011 |
20110134070 | CAPACITIVE TOUCH PANEL - A capacitive touch panel including a transparent substrate, a plurality of first metal wires, an insulation layer, a plurality of first sensing units, a plurality of second sensing units and a plurality of second metal wires are provided. The transparent substrate has a substrate surface on which the first metal wires, the first sensing units and the second sensing units are formed. The insulation layer can cover a portion of each first metal wire, which is connected to two of the first sensing units, wherein each second metal wire is connected to two of the second sensing units. | 06-09-2011 |
Toh Chin Hock, Singapore SG
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20090004777 | Stacked die semiconductor package and method of assembly - A method of manufacturing a plurality of stacked die semiconductor packages, including: attaching a second silicon wafer to a first silicon wafer, wherein the second silicon wafer has a plurality of open vias; attaching a third silicon wafer to the second silicon wafer, wherein the third silicon wafer has a plurality of open vias, and the open vias of the second and third silicon wafers are aligned with one another; etching a bonding material that attaches the wafers from the aligned open vias; filling the aligned open vias with a conductor; forming conductive bumps at open ends of the aligned open vias; back grinding the first silicon wafer; separating the stacked semiconductor dies from each other; attaching the bump end of the stacked semiconductor dies onto a substrate; encapsulating the stacked semiconductor dies and substrate; and singulating the encapsulated assembly. | 01-01-2009 |
Wojtek Hock, Etobicoke CA
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20080289006 | MEDIA FILE DISTRIBUTION SYSTEM AND METHOD - A file distribution method and system for distributing media files to authorized recipients. The method and system exploit the advantages of peer-to-peer file distribution protocols, such as BitTorrent, while maintaining security and control over the file distribution. A server farm containing a plurality of servers is placed behind the security of a distribution system, preventing unauthorized client devices from accessing the media files stored on the server farm. Media files are fragmented and stored on each of the plurality of servers within the server farm. Each server on the server farm features at least one IP address and each server is pre-seeded with a complete copy of the fragmented media file. Fragments are distributed to requesting authorized clients in accordance with a peer-to-peer file distribution protocol. | 11-20-2008 |