Patent application number | Description | Published |
20100140505 | CAPILLARY ELECTROPHORESIS FLUORESCENT DETECTION SYSTEM - The invention includes a high sensitivity and high throughput capillary electrophoresis multiwavelength florescence detection system. The fluorescent detection system is configured to illuminate a relatively large volume of a single capillary or a plurality of capillaries, with a pixelated detection system capable of imaging an area of each capillary that differentiates the capillary walls, the space between the capillaries, and the internal liquid volume within the capillary. Only the desired pixels or image area are used for processing and generating an output signal. | 06-10-2010 |
20100173304 | METHOD OF DNA SEQUENCING - The invention includes a method for sequencing DNA by partially sequencing the bases of complementary strands of double-stranded DNA and combining the partial information from both strands of the double strand DNA to fully sequence the DNA. The invention also includes DNA sequences sequenced by the methods, computer readable mediums including program instructions for such methods, and kits adapted to perform such methods. | 07-08-2010 |
20100209908 | SYSTEM AND METHOD FOR NUCLEOTIDE SEQUENCE PROFILING FOR SAMPLE IDENTIFICATION - The invention includes a method of sample profiling for identification. The method includes the steps of performing less than four nucleotide-specific chemical cleavage reactions to obtain nucleotide sequence fragments, performing size separation on the fragments, detecting the fragments' separation, generating a profile based on the detection, and comparing the profile to a data base to identify the sample. | 08-19-2010 |
20100264028 | METHOD FOR MULTIPLEXED CAPILLARY ELECTROPHORESIS SIGNAL CROSS-TALK CORRECTION - The present invention provides a simple method to correct cross-talk, after the data have been generated. Adjacent signals are simply subtracted from the original observed signal with a repeating process. The data processing is stopped when a predefined condition is met. By this technique, cross-talk can be reduced from >5% to less than 0.1%. And as an additional advantage, this method provides a way to correct the cross-talk without the need to know which peaks are caused by the adjacent capillary signal. | 10-21-2010 |
20110068007 | MULTI-WAVELENGTH FLUORESCENCE DETECTION SYSTEM FOR MULTIPLEXED CAPILLARY ELECTROPHORESIS - Using multiple dichroics mirrors to split and redirect different wavelength regions of light in a multi-wavelength fluorescence detection system. | 03-24-2011 |
20110120869 | METHOD FOR MULTIPLEXED CAPILLARY ELECTROPHORESIS SIGNAL CROSS-TALK CORRECTION - The present invention provides a simple method to correct cross-talk, after the data have been generated. Adjacent signals are simply subtracted from the original observed signal with a repeating process. The data processing is stopped when a predefined condition is met. By this technique, cross-talk can be reduced from >5% to less than 0.1%. And as an additional advantage, this method provides a way to correct the cross-talk without the need to know which peaks are caused by the adjacent capillary signal. | 05-26-2011 |
20130334049 | MULTI-COLOR DETECTION SYSTEM FOR MULTIPLEXED CAPILLARY ELECTROPHORESIS - A multi-wavelength detector for a multiplex capillary electrophoresis system comprising a linear filter placed in between the capillary detection windows and a 2-dimensional detector. The linear filter is oriented such that the change in wavelength of the filter is in the direction of flow of the fluid within the capillary detection windows. And a method for time shift correction and to merge all peaks into a single overlapped peak. | 12-19-2013 |
20140048722 | CAPILLARY ELECTROPHORESIS FLUORESCENT DETECTION SYSTEM - The invention includes a high sensitivity and high throughput capillary electrophoresis multiwavelength florescence detection system. The fluorescent detection system is configured to illuminate a relatively large volume of a single capillary or a plurality of capillaries, with a pixelated detection system capable of imaging an area of each capillary that differentiates the capillary walls, the space between the capillaries, and the internal liquid volume within the capillary. Only the desired pixels or image area are used for processing and generating an output signal. | 02-20-2014 |