Patent application number | Description | Published |
20100153168 | SYSTEM AND METHOD FOR CARRYING OUT AN INSPECTION OR MAINTENANCE OPERATION WITH COMPLIANCE TRACKING USING A HANDHELD DEVICE - The present invention is a system and method for inspections and compliance verification of industrial equipment using a handheld device. An inspector first segments an inspected component into logical inspection points. The inspector then scans a unique machine-readable tag, such as an RFID tag, with a handheld device at each logical inspection point. The inspector then takes a media sample, such as a digital photograph, of the physical component referred to by each corresponding logical inspection point. Then the inspector associates the media samples with the corresponding scan of the unique machine-readable tag. For each of the actions the inspector carries out on the handheld device, a timestamp is added that represents evidence of a date and a time of physical visitation to the associated logical inspection point. The inspector may then annotate the media samples in such ways that substantiate inspector statements of problems with inspected components found during inspection. | 06-17-2010 |
20100153833 | SYSTEM AND METHOD FOR GENERATING QUOTATIONS FROM A REFERENCE DOCUMENT ON A TOUCH SENSITIVE DISPLAY DEVICE - The present invention is a system and method for generating quotations from a reference document on a touch sensitive display device or other handheld device, including the following steps: (a) providing a reference document; (b) displaying the reference document; (c) capturing an image of a portion of the reference document; (d) editing the captured portion of the reference document; and (e) generating a quotation comprising an image quotation and a bibliographical reference to a referenced portion of the reference document. The present invention may be used in Apple iPhones®, hand-held devices that inspectors may use to quote reference documents to substantiate statements of problems found during industrial inspections, and in other purposes. | 06-17-2010 |
20100185549 | SYSTEM AND METHOD FOR CARRYING OUT AN INSPECTION OR MAINTENANCE OPERATION WITH COMPLIANCE TRACKING USING A HANDHELD DEVICE - The present invention is a system and method for inspections and compliance verification of industrial equipment using a handheld device. An inspector first segments an inspected component into logical inspection points. The inspector then scans a unique machine-readable tag, such as an RFID tag, with a handheld device at each logical inspection point. The inspector then takes a media sample, such as a digital photograph, of the physical component referred to by each corresponding logical inspection point. Then the inspector associates the media samples with the corresponding scan of the unique machine-readable tag. For each of the actions the inspector carries out on the handheld device, a timestamp is added that represents evidence of a date and a time of physical visitation to the associated logical inspection point. The inspector may then annotate the media samples in such ways that substantiate inspector statements of problems with inspected components found during inspection. | 07-22-2010 |
20100194781 | SYSTEM AND METHOD FOR CROPPING AND ANNOTATING IMAGES ON A TOUCH SENSITIVE DISPLAY DEVICE - The present invention is a system and method for cropping and annotating images on a touch sensitive display device or other handheld device, including the following steps: (a) displaying an image of the image file to be cropped/annotated; (b) receiving an first input from a user designating a first point in the image defining a corner of a crop/annotation rectangle; (c) receiving a second input from the user designating a second point in the image defining an opposite corner of the crop/annotation rectangle; and (d) cropping and/or annotating the image from the first point to the second point of the crop/annotation rectangle. The present invention may be used in digital cameras, Apple iPhones®, hand-held devices that inspectors may use to annotate photographs taken to substantiate statements of problems found during industrial inspections, and for other purposes. | 08-05-2010 |
Patent application number | Description | Published |
20110200848 | HIGH ENERGY DENSITY REDOX FLOW DEVICE - Redox flow devices are described in which at least one of the positive electrode or negative electrode-active materials is a semi-solid or is a condensed ion-storing electroactive material, and in which at least one of the electrode-active materials is transported to and from an assembly at which the electrochemical reaction occurs, producing electrical energy. The electronic conductivity of the semi-solid is increased by the addition of conductive particles to suspensions and/or via the surface modification of the solid in semi-solids (e.g., by coating the solid with a more electron conductive coating material to increase the power of the device). High energy density and high power redox flow devices are disclosed. The redox flow devices described herein can also include one or more inventive design features. In addition, inventive chemistries for use in redox flow devices are also described. | 08-18-2011 |
20110274948 | ENERGY TRANSFER USING ELECTROCHEMICALLY ISOLATED FLUIDS - The present invention is related to energy generation using electrochemically isolated fluids, and articles, systems, and methods for achieving the same. The embodiments described herein can be used in electrochemical cells in which at least one electrode comprises an electrochemically active fluid (i.e., the electrochemical cell comprises at least one fluid comprising electrode active material that is flowable into and/or out of the electrode compartment in which the electrode active material is charged and/or discharged). | 11-10-2011 |
20120164499 | STATIONARY, FLUID REDOX ELECTRODE - The present invention is related to electrochemical energy generation devices including at least one electrode comprising an electrochemically active fluid that is enclosed within the cell, as well as related articles, systems, and methods. In some embodiments, the anode and/or cathode of the electrochemical energy generation devices described herein can be formed of an electrochemically active fluid, such as a semi-solid or a redox active ion-storing liquid. The electrochemical energy generation device can be configured such that the anode and/or cathode can be flowed into their respective electrode compartments, for example, during assembly. During operation, on the other hand, little or none of the electrochemically active fluid(s) are transported into or out of the energy generation device (e.g., out of the electrode compartments of the electrochemical energy generation device). | 06-28-2012 |
20130344367 | HIGH ENERGY DENSITY REDOX FLOW DEVICE - Redox flow devices are described in which at least one of the positive electrode or negative electrode-active materials is a semi-solid or is a condensed ion-storing electroactive material, and in which at least one of the electrode-active materials is transported to and from an assembly at which the electrochemical reaction occurs, producing electrical energy. The electronic conductivity of the semi-solid is increased by the addition of conductive particles to suspensions and/or via the surface modification of the solid in semi-solids (e.g., by coating the solid with a more electron conductive coating material to increase the power of the device). High energy density and high power redox flow devices are disclosed. The redox flow devices described herein can also include one or more inventive design features. In addition, inventive chemistries for use in redox flow devices are also described. | 12-26-2013 |
Patent application number | Description | Published |
20080246559 | Lithographically-defined multi-standard multi-frequency high-Q tunable micromechanical resonators - Disclosed are micromechanical resonator apparatus having features that permit multiple resonators on the same substrate to operate at different operating frequencies. Exemplary micromechanical resonator apparatus includes a support substrate and suspended micromechanical resonator apparatus having a resonance frequency. In one embodiment, the suspended micromechanical resonator apparatus comprises a device substrate that is suspended from and attached to the support substrate, a piezoelectric layer formed on the suspended device substrate, and a plurality of interdigitated upper electrodes formed on the piezoelectric layer. In another embodiment, the suspended micromechanical resonator apparatus comprises a device substrate that is suspended from and attached to the support substrate, a lower electrode formed on the suspended device substrate, a piezoelectric layer formed on the lower electrode, and a plurality of interdigitated upper electrodes formed on the piezoelectric layer. The substrate may comprise a silicon substrate, or a semiconductor-on-insulator substrate, such as a diamond on silicon substrate. Additionally, lateral frequency-adjusting electrodes may be disposed adjacent to the resonator apparatus that are separated therefrom by a capacitive gap, and which are configured to receive a direct current voltage that adjusts the resonance frequency of the resonator apparatus. | 10-09-2008 |
20100066467 | Lithographically Defined Multi-Standard Multi-Frequency High-Q Tunable Micromechanical Resonators - Disclosed are micromechanical resonator apparatus having features that permit multiple resonators on the same substrate to operate at different operating frequencies. Exemplary micromechanical resonator apparatus includes a support substrate and suspended micromechanical resonator apparatus having a resonance frequency. In one embodiment, the suspended micromechanical resonator apparatus comprises a device substrate that is suspended from and attached to the support substrate, a piezoelectric layer formed on the suspended device substrate, and a plurality of interdigitated upper electrodes formed on the piezoelectric layer. In another embodiment, the suspended micromechanical resonator apparatus comprises a device substrate that is suspended from and attached to the support substrate, a lower electrode formed on the suspended device substrate, a piezoelectric layer formed on the lower electrode, and a plurality of interdigitated upper electrodes formed on the piezoelectric layer. The substrate may comprise a silicon substrate, or a semiconductor-on-insulator substrate, such as a diamond on silicon substrate. Additionally, lateral frequency-adjusting electrodes may be disposed adjacent to the resonator apparatus that are separated therefrom by a capacitive gap, and which are configured to receive a direct current voltage that adjusts the resonance frequency of the resonator apparatus. | 03-18-2010 |
Patent application number | Description | Published |
20100105609 | Processes for Preparing Eptifibatide - The present invention provides, inter alia, convergent processes for preparing eptifibatide that involve coupling a 2-6 eptifibatide fragment to an activated cysteinamide residue to form a 2-7 eptifibatide fragment, attaching a mercaptopropionic acid residue to the 2-7 eptifibatide fragment through disulfide bond formation, coupling the peptide intramolecularly, and removing the protecting group, to form eptifibatide. The invention further provides products produced by the described processes, novel compounds that can be used as synthetic intermediates for the preparation of eptifibatide, and novel compounds that are structurally similar to eptifibatide. | 04-29-2010 |
20110165075 | INTEGRIN TARGETING AGENTS AND IN-VIVO AND IN-VITRO IMAGING METHODS USING THE SAME - The invention provides a family of agents that target integrins, which can be used as imaging agents and/or therapeutic agents. The agents can be used to image angiogenesis, inflammation or other physiological processes in a subject. | 07-07-2011 |
20130309168 | BACTERIAL IMAGING AGENTS AND METHODS OF USING SAME - The invention provides a family of agents that target bacterial infection, which can be used as imaging agents or therapeutic agents. The agents can be used to image sites of bacterial infection as well as other physiological processes in a subject. | 11-21-2013 |
20140050662 | PROSTATE SPECIFIC ANTIGEN AGENTS AND METHODS OF USING SAME FOR PROSTATE CANCER IMAGING - The invention provides a family of agents that target the prostate specific antigen, which can be used as imaging agents or therapeutic agents. The agents can be used to image prostate cancer as well as other physiological processes in a subject. | 02-20-2014 |
20140170066 | INTEGRIN TARGETING AGENTS AND IN-VIVO AND IN-VITRO IMAGING METHODS USING THE SAME - The invention provides a family of agents that target integrins, which can be used as imaging agents and/or therapeutic agents. The agents can be used to image angiogenesis, inflammation or other physiological processes in a subject. | 06-19-2014 |
Patent application number | Description | Published |
20100298952 | MEDICAL IMPLANT - Disclosed is a self-expanding medical implant for placement within a lumen of a patient. The implant comprises a woven or non-woven structure having a substantially tubular configuration, and is designed to be low-profile such that it is deliverable with a small diameter catheter. The implant has a high recoverability and desired mechanical properties. | 11-25-2010 |
20110189475 | MEDICAL DEVICES CONTAINING ORIENTED FILMS OF POLY-4-HYDROXYBUTYRATE AND COPOLYMERS - Continuous processing methods for making absorbable polymeric films with one or more of the following properties: high toughness, low modulus, high tensile strength, and thickness less than 10 mm, more preferably less than 1 mm, and more preferably less than 100 μm, have been developed. In the preferred embodiment, the polymer is a polyhydroxyalkanoate, and in the most preferred embodiment, the polymer comprises 4-hydroxybutyrate. A particularly preferred embodiment is a film of poly-4-hydroxybutyrate or copolymer thereof, wherein the film has a tensile strength greater than 5.5 kgf/mm | 08-04-2011 |
20110238162 | MEDICAL IMPLANT - Disclosed is a self-expanding medical implant for placement within a lumen of a patient. The implant comprises a woven or non-woven structure having a substantially tubular configuration, and is designed to be low-profile such that it is deliverable with a small diameter catheter. The implant has a high recoverability and desired mechanical properties. | 09-29-2011 |
20110319987 | MEDICAL IMPLANT - Disclosed is a self-expanding medical implant for placement within a lumen of a patient. The implant comprises a woven or non-woven structure having a substantially tubular configuration, and is designed to be low-profile such that it is deliverable with a small diameter catheter. The implant has a high recoverability and desired mechanical properties. | 12-29-2011 |
20120143300 | MEDICAL IMPLANT - Disclosed is a self-expanding medical implant for placement within a lumen of a patient. The implant comprises a woven or non-woven structure having a substantially tubular configuration, and is designed to be low-profile such that it is deliverable with a small diameter catheter. The implant has a high recoverability and desired mechanical properties. | 06-07-2012 |
20130066295 | POLYMERIC IMPLANT DELIVERY SYSTEM - Delivery systems for a polymeric tubular implant, kits that include such delivery systems, and methods of treating patients by implanting tubular implants using the delivery systems. The delivery systems include an inner shaft, an expandable member slidably disposed about the inner shaft and configured to receive the tubular implant, and a tubular outer shaft disposed about the inner shaft. | 03-14-2013 |
20130158652 | MEDICAL IMPLANTS - Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants have a high recoverability and desired mechanical properties. | 06-20-2013 |
20130304177 | Drug Eluting Medical Implant - Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants have a high recoverability and desired mechanical properties. | 11-14-2013 |
20130317600 | DRUG ELUTING MEDICAL IMPLANT - Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants have a high recoverability and desired mechanical properties. | 11-28-2013 |
20140100644 | DRUG-ELUTING MEDICAL IMPLANTS - Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants have a high recoverability and desired mechanical properties. | 04-10-2014 |
20140121762 | MEDICAL IMPLANT - Disclosed is a self-expanding medical implant for placement within a lumen of a patient. The implant comprises a woven or non-woven structure having a substantially tubular configuration, and is designed to be low-profile such that it is deliverable with a small diameter catheter. The implant has a high recoverability and desired mechanical properties. | 05-01-2014 |
20140172074 | STENT WITH REINFORCED JOINTS - The present invention relates generally to stents for insertion into bodily lumens that include at least one strand that forms a self-expanding tubular structure. Specifically, these strands form a plurality of intersections at which one portion of the strand is in proximity to another portion of the same or different strand. More specifically, at least some of those intersections include a plurality of reinforcement members. | 06-19-2014 |
20160081830 | POLYMERIC IMPLANT DELIVERY SYSTEM - Delivery systems for a polymeric tubular implant, kits that include such delivery systems, and methods of treating patients by implanting tubular implants using the delivery systems. The delivery systems include an inner shaft, an expandable member slidably disposed about the inner shaft and configured to receive the tubular implant, and a tubular outer shaft disposed about the inner shaft. | 03-24-2016 |
Patent application number | Description | Published |
20090023173 | Luminescence-based methods and probes for measuring cytochrome P450 activity - The invention provides compounds, compositions, methods, substrates, and kits useful for analyzing the metabolic activity in cells, tissue, and animals and for screening test compounds for their effect on cytochrome P450 activity. In particular, a one-step and two-step methods using luminogenic molecules, e.g. luciferins or coelenterazines, that are cytochrome P450 substrates and that are also bioluminescent enzyme, e.g., luciferase, pro-substrates are provided. The present method further provides a method for stabilizing and prolonging the luminescent signal in a luciferase-based assay using luciferase stabilizing agents such as reversible luciferase inhibitors. | 01-22-2009 |
20110003316 | LUMINESCENCE-BASED METHODS AND PROBES FOR MEASURING CYTOCHROME P450 ACTIVITY - The present invention provides methods, compositions, substrates, and kits useful for analyzing the metabolic activity in cells, tissue, and animals and for screening test compounds for their effect on cytochrome P450 activity. In particular, a one-step and two-step methods using luminogenic molecules, e.g. luciferin or coelenterazines, that are cytochrome P450 substrates and that are also bioluminescent enzyme, e.g., luciferase, pro-substrates are provided. Upon addition of the luciferin derivative or other luminogenic molecule into a P450 reaction, the P450 enzyme metabolizes the molecule into a bioluminescent enzyme substrate, e.g., luciferin and/or luciferin derivative metabolite, in a P450 reaction. The resulting metabolite(s) serves as a substrate of the bioluminescent enzyme, e.g., luciferase, in a second light-generating reaction. Luminescent cytochrome P450 assays with low background signals and high sensitivity are disclosed and isoform selectivity is demonstrated. The present invention also provides an improved method for performing luciferase reactions which employs added pyrophosphatase to remove inorganic pyrophosphate, a luciferase inhibitor which may be present in the reaction mixture as a contaminant or may be generated during the reaction. The present method further provides a method for stabilizing and prolonging the luminescent signal in a luciferase-based assay using luciferase stabilizing agents such as reversible luciferase inhibitors. | 01-06-2011 |
20110081670 | LUCIFERASE-BASED ASSAYS - A method and kit are provided for enhancing the tolerance of an assay reagent to compounds in an assay sample, the assay reagent including a luciferase enzyme. The method includes contacting the luciferase with a tolerance enhancement agent in an amount sufficient to substantially protect luciferase enzyme activity from interference of the compound and minimize interference by at least about 10% relative to an assay not having tolerance enhancement agent. | 04-07-2011 |
20130217051 | LUCIFERASE-BASED ASSAYS - A method and kit are provided for enhancing the tolerance of an assay reagent to compounds in an assay sample, the assay reagent including a luciferase enzyme. The method includes contacting the luciferase with a tolerance enhancement agent in an amount sufficient to substantially protect luciferase enzyme activity from interference of the compound and minimize interference by at least about 10% relative to an assay not having tolerance enhancement agent. | 08-22-2013 |
20130217052 | LUCIFERASE-BASED ASSAYS - A method and kit are provided for enhancing the tolerance of an assay reagent to compounds in an assay sample, the assay reagent including a luciferase enzyme. The method includes contacting the luciferase with a tolerance enhancement agent in an amount sufficient to substantially protect luciferase enzyme activity from interference of the compound and minize interference by at least about 10% relative to an assay not having tolerance enhancement agent. | 08-22-2013 |
20140380514 | LUMINESCENCE-BASED METHODS AND PROBES FOR MEASURING CYTOCHROME P450 ACTIVITY - The invention provides compounds, compositions, methods, substrates, and kits useful for analyzing the metabolic activity in cells, tissue, and animals and for screening test compounds for their effect on cytochrome P450 activity. In particular, a one-step and two-step methods using luminogenic molecules, e.g. luciferins or coelenterazines, that are cytochrome P450 substrates and that are also bioluminescent enzyme, e.g., luciferase, pro-substrates are provided. The present method further provides a method for stabilizing and prolonging the luminescent signal in a luciferase-based assay using luciferase stabilizing agents such as reversible luciferase inhibitors. | 12-25-2014 |
20150337359 | LUCIFERASE-BASED ASSAYS - A method and kit are provided for enhancing the tolerance of an assay reagent to compounds in an assay sample, the assay reagent including a luciferase enzyme. The method includes contacting the luciferase with a tolerance enhancement agent in an amount sufficient to substantially protect luciferase enzyme activity from interference of the compound and minimize interference by at least about 10% relative to an assay not having tolerance enhancement agent. | 11-26-2015 |
Patent application number | Description | Published |
20110320111 | SYSTEM AND METHOD FOR PROVIDING ROAD CONDITION AND CONGESTION MONITORING USING SMART MESSAGES - A communication device for providing road conditions and monitoring congestion, contains a memory and a processor configured by the memory to perform the steps of: extracting key current vehicle and/or traffic insight; determining if the extracted key current vehicle and/or traffic insight represents a departure from expected vehicle and/or traffic insight; if the extracted key current vehicle and/or traffic insight is a departure from expected vehicle and/or traffic insight, using the key current vehicle and/or traffic insight to create a smart message, wherein the smart message contains the extracted key current vehicle and/or traffic insight; and if the extracted key current vehicle and/or traffic insight is a confirmation of expected vehicle and/or traffic insight, creating a confirmation message that does not contain the extracted key current vehicle and/or traffic insight, yet confirms similarity between the extracted key current vehicle and/or traffic insight and the expected vehicle and/or traffic insight. | 12-29-2011 |
20120065871 | SYSTEM AND METHOD FOR PROVIDING ROAD CONDITION AND CONGESTION MONITORING - A portable communication device for providing road conditions and monitoring traffic congestion for a user contains a device for sensing orientation of the portable communication device, including acceleration and/or deceleration of a vehicle in which the communication device is located, a memory, and a processor. The processor is configured by the memory to perform the step of calculating space time series data to determine traffic congestion characteristics, wherein the step of calculating space time series data includes at least one step selected from the group consisting of determining position of the portable communication device as a function of time, determining velocity of the portable communication device as a function of time, and determining acceleration of the portable communication device as a function of time. | 03-15-2012 |
20120255343 | LEAK DETECTION SYSTEM - The system includes structure for supporting at least one tube within a pipe. The tube has one end disposed close to, or in contact with, a wall of the pipe. A sensor is disposed within the at least one tube to detect a pressure gradient or fluid movement within the tube. Such pressure gradient or fluid movement indicates a leak in the pipe adjacent to the tube location. In a preferred embodiment, the structure is a ring sized to fit within the pipe and the ring supports a plurality of tubes. In another aspect, the tube includes a restriction to prevent flow and pressure is measured on each side of the restriction. | 10-11-2012 |