Hirst
Christopher Hirst, Sjobo SE
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20130190851 | DISPLACEMENT RESISTANT MICROELECTRODE, MICROELECTRODE BUNDLE AND MICROELECTRODE ARRAY - A medical microelectrode has a front end, a rear end and a density at 20° C. of from 0.80 to 1.15. The electrode comprises any of: electrically conductive tubiform lead comprising a metal and/or an electrically conductive polymer, the lead having an outer surface and a sealed lumen; electrically conductive wire lead comprising a metal and/or an electrically conductive polymer, the lead having a surface and a buoyant element of a density of less than 1.0 attached to the surface. | 07-25-2013 |
George David Scarcliffe Hirst, Victoria AU
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20100010290 | Smooth muscle implant for managing a medical condition - The present invention relates to an implant for managing a medical condition. In particular, it relates to medical treatments which employ smooth muscle implant and discloses a method of augmenting a smooth muscle implant for management of a human medical condition. Augmentation may be by a number of methods. It may be by utilising neurotrophic or trophic factors to assist growth of the smooth muscle tissue or nerve growth within the smooth muscle tissue, or revascularisation of the smooth muscle tissue. It may be by utilising tissue engineering to grow smooth muscle tissue. It may be by adding proliferative smooth muscle cells and/or smooth muscle stem cells for the smooth muscle. | 01-14-2010 |
Graeme Hirst, Toronto CA
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20130297216 | METHOD AND SYSTEM OF LONGITUDINAL DETECTION OF DEMENTIA THROUGH LEXICAL AND SYNTACTIC CHANGES IN WRITING - The present invention is a method and system for detecting linguistic markers as signs and indicators of mental illness, even prior to onset of symptoms of the mental illness. The linguistic markers may be detected in diachronic analyses of writing or speech samples. In particular, the present invention may identify lexical and syntactic changes in language due to mental illness. To recognize such changes the present invention may utilize complete, fully parsed texts or speech representing a number of measures. The identification of markers may provide a means of detecting mental illness early on based on a person's use of language. The language may be presented as spontaneous speech or writing, and may include samples of speech and/or writing occurring over time. | 11-07-2013 |
Graeme John Hirst, Toronto CA
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20140195227 | SYSTEM AND METHOD FOR ACOUSTIC TRANSFORMATION - An acoustic transformation system and method. A specific embodiment is the transformation of acoustic speech signals produced by speakers with speech disabilities in order to make those utterances more intelligible to typical listeners. These modifications include the correction of tempo or rhythm, the adjustment of formant frequencies in sonorants, the removal of adjustment of aberrant voicing, the deletion of phoneme insertion errors, and the replacement of erroneously dropped phonemes. These methods may also be applied to general correction of musical or acoustic sequences. | 07-10-2014 |
Lawrence William Hirst, South Brisbane AU
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20100275650 | Method and Apparatus for Recovery of Suspended Biological Material - An apparatus for recovery of suspended biological material from a suspension solution, the apparatus including a suspension solution container to temporarily hold the suspension solution, extraction means to apply extractive force to the container to extract the suspension solution temporarily held therein and the filter means sized to separate the suspended biological material from the suspension solution. | 11-04-2010 |
Les Hirst, Waterloo CA
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20100026973 | EXPANDING CHASSIS FOR IMAGING SYSTEMS - An expanding chassis for an imaging unit is provided, the expanding chassis for use in imaging systems having a plurality of imaging units arranged in an array. The expanding chassis comprises a rigid frame for housing a light engine and related circuitry, and for mounting a screen on a front surface of the rigid frame for use with the light engine. The expanding chassis further comprises at least one expandable interface pad on at least one side of the rigid frame. The rigid frame and the expandable interface pad have a combined thermal expansion characteristic that provides an overall expansion in the expanding chassis that substantially matches the expansion of the screen. | 02-04-2010 |
20110149491 | EXPANDING CHASSIS FOR IMAGING SYSTEMS - An expanding chassis for an imaging unit is provided, the expanding chassis for use in imaging systems having a plurality of imaging units arranged in an array. The expanding chassis comprises a rigid frame for housing a light engine and related circuitry, and for mounting a screen on a front surface of the rigid frame for use with the light engine. The expanding chassis further comprises at least one expandable interface pad on at least one side of the rigid frame. The rigid frame and the expandable interface pad have a combined thermal expansion characteristic that provides an overall expansion in the expanding chassis that substantially matches the expansion of the screen. | 06-23-2011 |
20110279352 | THERMAL ACTUATOR FOR CONFIGURABLE IMAGING SYSTEMS - For use in an imaging system having a plurality of adjacent display units, the improvement comprising a thermal actuator in at least one of the display units for moving a screen thereof away from a chassis thereof when the said display unit exceeds a predetermined temperature, so as to prevent mechanical interference between the adjacent display units. | 11-17-2011 |
20110304523 | COINCIDENT FASTENERS FOR CONFIGURABLE IMAGING SYSTEMS - A coincident fastener for use with a display unit of a configurable imaging system, comprising a screw for insertion through the display unit, wherein the screw includes a head portion, a threaded male portion at an end of the screw opposite the head portion, and an anti-rotation locking mechanism for locking the screw relative to the display unit. | 12-15-2011 |
Martin Hirst, Delta CA
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20110195070 | DETECTION OF GRANULOSA-CELL TUMORS - A method of detecting a granulosa-cell tumor is described herein. The method involves detecting a mutation in a sample derived from a subject, indicative of substitution of tryptophan in place of cysteine at amino acid position 134 of FOXL2 protein. The mutation may be detected as a DNA mutation 402C>G in the FOXL2 gene. Methods for screening for a granulosa-cell tumor from a blood-based assay are provided, as well as methods for making a determination that an ovarian tumor is not a granulosa-cell tumor. Kits for granulosa-cell tumors are described, and a method of treating a granulosa-cell tumor are also described. | 08-11-2011 |
20130102477 | BIOMARKERS FOR NON-HODGKIN LYMPHOMAS AND USES THEREOF - The disclosure provides a method of identifying a subject as having B-cell non-Hodgkin lymphoma (NHL) such as testing a sample from a subject for a mutation in one or more biomarkers. Also described are methods for classifying or monitoring a subject having, or suspected of having, B-cell non-Hodgkin lymphoma comprising testing the sample for a mutation in one or more biomarkers. | 04-25-2013 |
20130195843 | Biomarkers for Non-Hodgkin Lymphomas and Uses Thereof - The disclosure provides a method of identifying a subject as having B-cell non-Hodgkin lymphoma (NHL) such as testing a sample from a subject for a mutation in one or more biomarkers. Also described are methods for classifying or monitoring a subject having, or suspected of having, B-cell non-Hodgkin lymphoma comprising testing the sample for a mutation in one or more biomarkers. | 08-01-2013 |
20130197056 | NOVEL BIOMARKERS AND TARGETS FOR OVARIAN CARCINOMA - Novel biomarkers and targets associated with ovarian cancer, particularly clear-cell carcinoma, endometrioid carcinoma, and uterine carcinoma, are disclosed. Mutations in genes encoding proteins that form part of the SWI/SNF chromatin remodelling protein complex, including ARID1A, or loss of expression of such proteins, including BAF250a, can be used to evaluate the likelihood endometriosis will progress or transform to cancer, to provide a prognosis for a patient with cancer, to assess whether conventional treatment is likely to be effective against a cancer, and/or in a synthetic lethal screen to identify novel targets and therapeutics for the treatment of cancer. | 08-01-2013 |
20140342920 | Biomarkers for Non-Hodkin Lymphomas and Uses Thereof - The disclosure provides a method of identifying a subject as having B-cell non-Hodgkin lymphoma (NHL) such as testing a sample from a subject for a mutation in one or more biomarkers. Also described are methods of classifying or monitoring a subject having, or suspected of having, B-cell non-Hodgkin lymphoma comprising testing the same for a mutation in one or more biomarkers. | 11-20-2014 |
Paul Ronald Hirst, Redland Bay AU
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20100112630 | METHODS FOR MEASURING MICROBIOLOGICAL CONTENT IN AQUEOUS MEDIA - A process for measuring total microbiological content in an aqueous medium includes adding a fluorescent dye to the aqueous medium, measuring the fluorescent signal in the aqueous medium to obtain a baseline fluorescent signal, releasing intracellular content of the microbiological matter into the aqueous medium by lysing the microbiological matter, measuring the fluorescent signal in the aqueous medium with the released intracellular content of the microbiological matter to obtain a second fluorescent signal, subtracting the baseline signal from the second fluorescent signal to obtain a net fluorescent signal and equating the net fluorescent signal with a microbiological content. Methods for measuring biofilm and adjusting for background noise are also provided. | 05-06-2010 |
Tim Hirst, Yarralumla AU
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20130122045 | Cross-Protective Influenza Vaccine - The invention relates to a method for preventing or treating an influenza virus infection in a subject, the method comprising administering to the subject a therapeutically effective amount of a gamma-irradiated influenza virus, wherein the virus comprises an A/Port Chalmers/1/73 (A/PC) strain backbone of PB2, PB1, PA, NP, M1, M2 and NEP proteins. | 05-16-2013 |
20140079732 | COMBINATION VACCINES - The present invention relates to the field of vaccines. More specifically the present invention relates to compositions and methods for enhancing immune responses induced by vaccines, including vaccines targeted at secondary infections and conditions associated with influenza infection. | 03-20-2014 |
Timothy R. Hirst, Manuka AU
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20120003267 | Therapeutic Agents - A method for treating an rheumatoid arthritis in a mammalian subject in need of same wherein the method comprises: administering to the mammalian subject an agent capable of modulating a ganglioside GM-1 associated activity in an amount effective to treat the disease. | 01-05-2012 |
Timothy Raymond Hirst, Manuka AU
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20140322274 | Therapeutic Agents - A method for treating an rheumatoid arthritis in a mammalian subject in need of same wherein the method comprises: administering to the mammalian subject an agent capable of modulating a ganglioside GM-1 associated activity in an amount effective to treat the disease. | 10-30-2014 |
Timothy Raymond Hirst, Forrest AU
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20080305125 | Mutant Forms Of EtxB and CtxB And Their Use As Carriers - The present invention describes the use of a mutant form of EtxB or CtxB to deliver an agent to a target cell wherein the mutant has GM-1 binding activity; but wherein the mutant has a reduced immunogenic and immunomodulatory activity relative to the wild type form of EtxB or CtxB. | 12-11-2008 |
William Joseph Senior Hirst, Amsterdam NL
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20110213554 | METHOD AND SYSTEM FOR SCREENING AN AREA OF THE ATMOSPHERE FOR SOURCES OF EMISSIONS - A method for remotely screening a selected area of the atmosphere for the presence of emissions into the atmosphere comprises moving a mobile platform, such as an aircraft, which carries an atmospheric component sensor in a pattern over and in the vicinity of the selected area, measuring the concentration of a component of the atmosphere at one or more points along the pattern with the atmospheric component sensor to obtain concentration data, obtaining supplementary data, and using an inverse dispersion technique, that utilizes the concentration data with the supplementary data to detect and locate one or more sources of emissions, and to determine the emitted mass release rates and/or surface fluxes. | 09-01-2011 |