Hile
David Hile, Westborough, MA US
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20110224410 | Buffers for Controlling the pH of Bone Morphogenetic Proteins - The present invention provides formulations of cysteine knot proteins, including TGF-β superfamily proteins and bone morphogenic proteins that are pH stabilized. In particular, the present invention relates to the observation that certain buffers enhance the stability of cysteine knot proteins, including TGF-β superfamily proteins and bone morphogenic proteins. In particular, disclosed herein are liquid and lyophilized formulations prepared with a glycylglycine and tartaric acid buffers to stabilize the pH of the formulation. | 09-15-2011 |
20130172254 | Buffers for Controlling the pH of Bone Morphogenetic Proteins - The present invention provides formulations of cysteine knot proteins, including TGF-β superfamily proteins and bone morphogenic proteins that are pH stabilized. In particular, the present invention relates to the observation that certain buffers enhance the stability of cysteine knot proteins, including TGF-β superfamily proteins and bone morphogenic proteins. In particular, disclosed herein are liquid and lyophilized formulations prepared with a glycylglycine and tartaric acid buffers to stabilize the pH of the formulation. | 07-04-2013 |
David D. Hile, Westborough, MA US
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20140336114 | Buffers for Controlling the pH of Bone Morphogenetic Proteins - The present invention provides formulations of cysteine knot proteins, including TGF-β superfamily proteins and bone morphogenic proteins that are pH stabilized. In particular, the present invention relates to the observation that certain buffers enhance the stability of cysteine knot proteins, including TGF-β superfamily proteins and bone morphogenic proteins. In particular, disclosed herein are liquid and lyophilized formulations prepared with a glycylglycine and tartaric acid buffers to stabilize the pH of the formulation. | 11-13-2014 |
20160038612 | FORMULATION AND DELIVERY OF MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS - The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity. | 02-11-2016 |
Glenn Cornell Hile, Monroeville, IN US
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20120222154 | VARIETY CORN LINE NPJC6794 - The present invention provides an inbred corn line designated NPJC6794, methods for producing a corn plant by crossing plants of the inbred line NPJC6794 with plants of another corn plant. The invention further encompasses all parts of inbred corn line NPJC6794, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line NPJC6794, and plants produced according to these methods. | 08-30-2012 |
20120222157 | VARIETY CORN LINE NPFA6899 - The present invention provides an inbred corn line designated NPFA6899, methods for producing a corn plant by crossing plants of the inbred line NPFA6899 with plants of another corn plant. The invention further encompasses all parts of inbred corn line NPFA6899, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line NPFA6899, and plants produced according to these methods. | 08-30-2012 |
20130227738 | VARIETY CORN LINE FF6224 - The present invention provides an inbred corn line designated FF6224, methods for producing a corn plant by crossing plants of the inbred line FF6224 with plants of another corn plant. The invention further encompasses all parts of inbred corn line FF6224, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line FF6224, and plants produced according to these methods. | 08-29-2013 |
20140137285 | VARIETY CORN LINE FF6788 - The present invention provides an inbred corn line designated FF6788, methods for producing a corn plant by crossing plants of the inbred line FF6788 with plants of another corn plant. The invention further encompasses all parts of inbred corn line FF6788, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line FF6788, and plants produced according to these methods. | 05-15-2014 |
20150033402 | VARIETY CORN LINE JDC7199 - The present invention provides an inbred corn line designated JDC7199, methods for producing a corn plant by crossing plants of the inbred line JDC7199 with plants of another corn plant. The invention further encompasses all parts of inbred corn line JDC7199, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line JDC7199, and plants produced according to these methods. | 01-29-2015 |
20150033405 | VARIETY CORN LINE JFF6785 - The present invention provides an inbred corn line designated JFF6785, methods for producing a corn plant by crossing plants of the inbred line JFF6785 with plants of another corn plant. The invention further encompasses all parts of inbred corn line JFF6785, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line JFF6785, and plants produced according to these methods. | 01-29-2015 |
20150237818 | VARIETY CORN LINE ID5754 - The present invention provides an inbred corn line designated ID5754, methods for producing a corn plant by crossing plants of the inbred line ID5754 with plants of another corn plant. The invention further encompasses all parts of inbred corn line ID5754, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line ID5754, and plants produced according to these methods. | 08-27-2015 |
Harlan Hile, Seattle, WA US
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20110098918 | Navigation Images - A computer-implemented navigational method includes transmitting, from a mobile computing device to a computer server system, data that can be used to determine a start point and an end point of a trip. The method also includes receiving navigational information defining a route between the start point and the end point, and a plurality of digital photographic images that have previously been taken along the route, sensing motion of the mobile computing device along the route, and displaying updated images from the plurality of images that substantially match a geographic position of the mobile computing device along the route. | 04-28-2011 |
20120022786 | Navigation Images - A computer-implemented navigational method includes transmitting, from a mobile computing device to a computer server system, data that can be used to determine a start point and an end point of a trip. The method also includes receiving navigational information defining a route between the start point and the end point, and a plurality of digital photographic images that have previously been taken along the route, sensing motion of the mobile computing device along the route, and displaying updated images from the plurality of images that substantially match a geographic position of the mobile computing device along the route. | 01-26-2012 |
20150332487 | ENCODING POLYGON DATA FOR FAST RETRIEVAL AND RENDERING - An indexed list of vertices is generated to represent a polygon. The indexed list is ordered so as to define one or more boundaries of a polygon, where each element in the indexed list of vertices specifies respective coordinates in an at least two-dimensional space. A description of several component shapes that make up the polygon is generated, where the description includes indices into the indexed list of vertices. The indexed list of vertices and the description of the component shapes are provided to a computing device for rendering the polygon. | 11-19-2015 |
Harlan Gerhardt Hile, Seattle, WA US
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20150117796 | METHOD AND SYSTEM FOR PRIORITIZING POINTS OF INTEREST FOR DISPLAY IN A MAP - Systems, methods, and machine-readable media for prioritizing points of interest for display in a map have been described. In certain aspects a system may include an interface module, a search module, and a priority module. The interface module may be configured to obtain pattern recognition data and location data associated with an image of a geographical area. The search module may be configured to access a set of point of interest listings and determine whether the pattern recognition data and the location data associated with the image correspond with a point of interest listing in the set of point of interest listings. The priority module may be configured to prioritize the point of interest listing for display in a map if a point of interest listing in the set of point of interest listings is determined to correspond. | 04-30-2015 |
Jeffrey B. Hile, Wexford, PA US
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20080276766 | Locking Pliers with CAM - A pair of locking pliers having an adjusting device that utilizes a cam assembly. The pliers, preferably, include a trolley disposed in a first handle member that defines a channel. The trolley is structured to be coupled to a link assembly wherein the position of the link assembly relative to the distal end of the first handle member affects the spacing of the pliers' jaws. The cam assembly is, preferably, a planar disk-like body having a radially extending handle and, preferably, a plurality of flats about the circumference. The cam assembly is disposed, preferably, in the plane defined by the first handle member and the second handle assembly. The cam is coupled to the first handle member at the distal end of the handle portion and its' axis extends generally perpendicular to the plane defined by the first handle member and the second handle assembly. At this location, the cam plurality of flats are structured to engage the trolley/cam follower as the cam handle extends beyond the first handle member distal end. Rotation of the cam causes the trolley, and therefore link assembly, to move relative to the distal end of the first handle member. | 11-13-2008 |
20100186558 | Locking pliers with quick jaw release - A jaw release mechanism for locking pliers which utilize an over-center toggle locking mechanism and wherein the normally stationary upper jaw of the pliers is pivotally fastened to the main body of the pliers. This normally stationary upper jaw is releaseably retained in a normally stationary position relative to the main body of the pliers by a thumb actuated trigger release mechanism whereby the locked pliers may be safely released with the same hand which grasps and manipulates the pliers. | 07-29-2010 |
John Hile, Withcott AU
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20150343865 | Safety Enhanced Turntable or Fifth Wheel for Coupling a Semi-Trailer to a Prime Mover - A method for assisting in the coupling of a semi-trailer to a turntable of a prime mover includes remotely monitoring sensors about the turntable to make a number of determinations. These include that the semitrailer is suitably close to the turntable for correct coupling. That a locking member, e.g. a kingpin, of the semitrailer is correctly positioned relative to the turntable for proper coupling. That a kingpin locking mechanism of the turntable is in a locked configuration. The result of the determinations is indicated to an operator of the prime mover. | 12-03-2015 |
Michael Alan Hile, Cincinnati, OH US
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20140286756 | DEVICE, SYSTEM AND METHOD FOR PREVENTING LEAKAGE IN A TURBINE - A turbine disk and blade assembly comprises a turbine disk including a plurality of disk posts extending radially therefrom and a plurality of disk slots between adjacent disk posts. The turbine disk is of a first material having a first coefficient of thermal expansion. The assembly further comprises a plurality of turbine blades. One of the turbine blades is received in each disk slot. The turbine blades are of a second material having a second coefficient of thermal expansion. The assembly further comprises a plurality of seal plates, wherein one of the seal plates is positioned in each disk slot radially inward of the turbine blade. The seal plates are of a material having a coefficient of thermal expansion substantially similar to that of either the disk posts or the turbine blade. | 09-25-2014 |
Samuel James Hile, St Peters AU
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20160125310 | APPARATUS AND METHOD FOR QUANTUM PROCESSING - The present disclosure provides a quantum processor realised in a semiconductor material and method to operate the quantum processor to implement adiabatic quantum computation. The quantum processor comprises a plurality of qubit elements disposed in a two-dimensional matrix arrangement. The qubits are implemented using the nuclear or electron spin of phosphorus donor atoms. Further, the processor comprises a control structure with a plurality of control members, each arranged to control a plurality of qubits disposed along a line or a column of the matrix. The control structure is controllable to perform adiabatic quantum error corrected computation. | 05-05-2016 |
20160125311 | APPARATUS AND METHOD FOR QUANTUM PROCESSING - The present disclosure provides a quantum processor realised in a semiconductor material and method to operate the quantum processor to implement error corrected quantum computation. The quantum processor comprises a plurality of qubit elements disposed in a two-dimensional matrix arrangement. The qubits are implemented using the nuclear or electron spin of phosphorus donor atoms. Further, the processor comprises a control structure with a plurality of control members, each arranged to control a plurality of qubits disposed along a line or a column of the matrix. The control structure is controllable to perform topological quantum error corrected computation. | 05-05-2016 |
Wayne Hile, Round Lake Park, IL US
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20100141440 | METHOD AND APPARATUS FOR VISUAL SILENT ALARM INDICATOR - An apparatus and method thereof wherein a portable computer system or personal digital assistant generates a visual signal in response to an occurrence of a programmed event. For example, the portable computer system can use a light emitting diode to visually signal an alarm at a specified time. The visual signal can be varied in order to indicate the type of event associated with the alarm. In one implementation, the visual signal blinks at a particular rate depending on the type of event. In another implementation, the visual signal blinks a prescribed number of times or according to a particular pattern depending on the type of event. When enabled, the visual signal is generated in lieu of an audible signal, thus providing to the user a silent alarm that does not disturb other people in proximity, such as in a meeting, a theater, or some other gathering. | 06-10-2010 |
20120112921 | METHOD AND APPARATUS FOR VISUAL SILENT ALARM INDICATOR - A handheld computer includes a processor; a memory in communication with the processor; and at least one light-emitting device that emits visible light as a visual indicator of an occurrence of a designated event. The processor is programmed to selectively activate the visual indicator in response to an occurrence of a designated event to provide the visual indicator to a user of the handheld computer. The processor is programmed to monitor for occurrence of two or more different types of designated events. The processor varies the visual indicator based on the type of the event for which occurrence is being signaled by that visual indicator, such that a different visual indicator is associated with each type of event for which the processor is programmed to monitor. | 05-10-2012 |