Heather R.
Heather R. Christofk, Carlsbad, CA US
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20100099726 | INHIBITORS OF PYRUVATE KINASE AND METHODS OF TREATING DISEASE - The invention provides pharmaceutical compositions, kits, and methods of treating cancer, diabetes, obesity, autoimmune disease, and benign prostatic hyperplasia using compounds that selectively inhibit pyruvate kinase M2 and an assay measuring chemical modulation of pyruvate kinase activity. | 04-22-2010 |
20110046083 | ACTIVATORS OF PYRUVATE KINASE M2 AND METHODS OF TREATING DISEASE - The invention described herein features methods, compositions, and kits for the use of activators of PKM2 for the treatment, prevention, or amelioration of diseases related to PKM2 function, including, e.g., cancer, diabetes, atherosclerosis, restenosis, obesity, autoimmune disorders, and proliferative disorders. | 02-24-2011 |
Heather R. Devantier, Philadelphia, PA US
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20090205581 | High-throughput operant sensory discrimination apparatus and method - Described herein are various apparatus and systems useful in sensory discrimination. Through the use of a multi-well sample plate, the high-throughput analysis apparatus and method allow for rapid sensory discrimination of a large number of samples. | 08-20-2009 |
Heather R. Falcon-Labry, Montgomery, TX US
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20100116221 | Animal Restraint System - An animal restraint system includes a vest configured to surround an animal extending from around the animal's neck. The vest includes front and rear ends, opposed first and second sides, a top, bottom, neck opening at the front end, two leg openings, and first and second shoulder areas. A ring is coupled to the vest at the first shoulder area, a first lateral loop is coupled to the vest at the top, and a first lateral loop is coupled to the vest at the first side. The system includes a first crossing loop. A strap is configured to pass through the first lateral loop and first crossing loop, respectively, the strap having opposed ends with fasteners. The strap extends along the first side when passing through the first lateral loop, the strap extending from the first to the second side when the strap passes through the first crossing loop. | 05-13-2010 |
Heather R. Murphy, Herriman, UT US
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20150101616 | Securable Procedure Kit - A procedure kit that removably retains components to be used during a medical procedure, such as the insertion of a catheter into a patient, is disclosed. The procedure kit is securable to a surface or structure such that the kit is positioned as desired by the clinician, thus minimizing chances that the kit will fall to the ground or undesirably move. In one embodiment, the procedure kit comprises a body defining a plurality of pockets that are sized to removably receive therein components for use in the medical procedure, an openable flap that covers at least a portion of the pockets; and an adhesive portion included on a portion of the body to enable the procedure kit to be secured to a structure or surface proximate to the patient, such as the sterile drape covering the patient. | 04-16-2015 |
Heather R. Nonnenmann, Warminster, PA US
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20080294131 | Disposable absorbent article and polymer film having odor control and/or skin health agents - A disposable absorbent article with an associated polymer film that is positioned to be activated by contact with bodily fluids, wherein the polymer film can release odor control and/or skin wellness agents upon contact with such bodily fluids. The polymer film can release the odor control and/or skin wellness agents immediately, gradually over a period of time after contact with such bodily fluids, or a combination of both. The polymer film can also be used for household cleaning applications, in which the polymer film can similarly contain and subsequently release household cleaning agents upon contact with water. | 11-27-2008 |
20090240228 | ADJUSTABLE ABSORBENT ARTICLE FOR IMPROVED FIT - Apparatus and methods of manufacturing absorbent articles suitable for use as training pants or other hygiene products are provided. The absorbent article includes a chassis having a front section, a rear section, and a crotch section extending between the front section and the rear section. The front section is connected to the rear section to define a waist opening, leg openings, and a belly region positioned between the waist opening and the leg openings. The absorbent article also includes an absorbent core coupled to the crotch section of the chassis. An adjustable tensioner is coupled to the chassis and is positioned for snugging the chassis against a wearer of the absorbent article. The tensioner is configured to be adjusted by the wearer from a first tension to a second, selected tension. | 09-24-2009 |
Heather R. Sanders, Rsm, CA US
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20150299811 | NUCLEIC ACID DETECTION COMBINING AMPLIFICATION WITH FRAGMENTATION - Provided herein are methods and compositions for detection of a nucleic acid target in a sample. The methods and compositions use primer directed amplification in conjunction with nucleic acid fragmentation. The methods have high sensitivity even in the presence of a large amount of non-target nucleic acid. Also provided are oligonucleotides and kits useful in the method. Exemplary nucleic acid targets are those with mutant gene sequence such as mutant sequence of the EGFR, APC, TMPRSS2, ERG and ETV1 genes. | 10-22-2015 |
Heather R. Sullens, Cupertino, CA US
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20150357815 | RECONFIGURABLE MULTIPLE-OUTPUT POWER-DELIVERY SYSTEM - The disclosed embodiments provide a system that operates a power supply. During operation, the system obtains power states of two or more loads coupled to two or more power converters in the power supply. Next, the system generates one or more control signals for a set of switching mechanisms to configure a coupling of the two or more loads to the two or more power converters through the switching mechanisms based on the power states. | 12-10-2015 |
Heather R. Sullens, San Francisco, CA US
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20120105162 | RESONANT OSCILLATOR WITH START UP AND SHUT DOWN CIRCUITRY - A system which starts up and shuts down a resonant oscillator circuit. During start up, the system operates a driving circuit, which is external to the resonant oscillator circuit, wherein the driving circuit uses a first clock signal to control a first phase output of the resonant oscillator circuit. At the same time, the driving circuit uses a second clock signal to control a second phase output of the resonant oscillator circuit, wherein the first and second clock signals have opposite phases. While the first and second phase outputs are being controlled, the system ramps up an input voltage, which is used to power the resonant oscillator circuit, wherein the ramping takes place across multiple initial oscillation periods. During shut down, the system shuts down the resonant oscillator circuit by ramping down the input voltage. Next, the system clamps the first and second phase outputs to a fixed voltage. | 05-03-2012 |
20120195080 | HIGH-VOLTAGE REGULATED POWER SUPPLY - The disclosed embodiments relate to a power-supply circuit, an electronic device that includes the power-supply circuit, and a method for generating high-voltage DC power from AC line power using the power-supply circuit. This power-supply circuit includes a voltage multiplier and a low dropout (LDO) regulator, and does not include a step-up transformer. Conventional power supplies often use a custom step-up transformer, which is expensive unless the power supplies are manufactured in high quantities. In contrast, one embodiment of the present disclosure provides a solid-state implementation of a 700 V regulated power supply that can take up to a 1020 V input from an 6× voltage multiplier powered from the AC mains. Hence, the disclosed power-supply circuit eliminates the need for large, heavy and expensive step-up transformers and chokes that are used in conventional high-voltage DC power supplies. | 08-02-2012 |