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| 20130159068 | SYSTEM AND METHOD FOR DETERMINING QUALITY OF SERVICE FOR ACTIONS TO BE PERFORMED IN A VIRTUAL SPACE - A virtual space may be provided to users. In providing the virtual space to users, actions performed in the virtual space responsive to user input may be dynamically assigned a quality of service that is dependent on one or more of user value, past user action requests, past action requests cumulatively for all users, server health, and/or other criteria. This may facilitate an operator of the virtual space increasing overall user engagement and/or value, and/or provide other enhancements. | 06-20-2013 |
| 20130172085 | System And Method For Facilitating Access To An Online Game Through A Plurality Of Social Networking Platforms - Participation in an online game through a plurality of different social network platforms may be facilitated. This may include enabling an individual user to log in to the online game, which may take place in a virtual space, through a plurality of different social network platforms, thereby extending the accessibility of the online game with respect to the individual user. The online game may be provided to users through different social network platforms such that a first user accessing the online game through a first social network platform may access a common instance of the online game (and/or the virtual space) with a second user accessing the online game through a second social network platform. | 07-04-2013 |
| 20140323213 | SYSTEM AND METHOD FOR ENHANCED VIDEO OF GAME PLAYBACK - One aspect of the disclosure relates to facilitating the development and provision of enhanced video of game playback, including the ability to augment a video of game playback with information relating to the game state of the game. A video may be generated based on game state information associated with one or more selected portions of the game. The video may include visual features that may not have been present in corresponding views that were presented to the user during game play of those one or more portions of the game. The user may augment the video with displayed information based on game logic for the online game. For example, displayed information may include commentary, tips on how the user could have maximized his game play, influential plays from the one or more portions of the game, and/or other information based on the game logic. | 10-30-2014 |
| 20140359476 | SYSTEM AND METHOD FOR FORWARDING EXTERNAL NOTIFICATIONS OF EVENTS IN A VIRTUAL SPACE FROM A PRESENTATION CONTROL DEVICE TO A USER DEVICE - Notifications of events that take place within a virtual space and/or information related the notifications may be transmitted from a server which hosts an instance of the virtual space to the presentation control device via which users may interact with the virtual space. Based on the received notifications and/or the information related to those notifications, the presentation control device may transmit external notifications to one or more user devices that are within the vicinity of the presentation control device. The external notifications may be sent, for example, via email, text message, instant message (external from the virtual space), push notification and/or through other external communication media. Determining a particular user device to which the presentation control device should transmit the event notification may depend on whether the user device is located within the vicinity of the presentation control device, a predefined association between a user and the user device, and/or whether the user is present at the user device. | 12-04-2014 |
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| 20110317013 | AUTOFOCUS CAMERA SYSTEMS AND METHODS - In an example embodiment, a method for focusing a miniature camera includes applying a signal to an actuator in the camera, moving a MEMS stage movably supported by one or more flexures in response to the application of the signal, moving a lens in response to the moving of the MEMS stage, and limiting movement of the MEMS stage to substantially one degree of freedom corresponding to an optical axis of the lens. | 12-29-2011 |
| 20130128099 | AUTOFOCUS CAMERA SYSTEMS AND METHODS - A method for focusing a miniature camera includes providing a current through a coil, moving a lens of a camera based on the current to adjust a focus of the camera, and limiting movement of the lens along an optical path of the camera. | 05-23-2013 |
| 20140184892 | AUTOFOCUS CAMERA SYSTEMS AND METHODS - A method for focusing a miniature camera includes providing a current through a coil, moving a lens of a camera based on the current to adjust a focus of the camera, and limiting movement of the lens along an optical path of the camera. | 07-03-2014 |
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| 20130079325 | PYRIDINE AND PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS - Pyridine and pyrimidine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like. | 03-28-2013 |
| 20130225552 | HETEROBICYCLIC COMPOUNDS - Heterobicyclic compounds of Formula (I): | 08-29-2013 |
| 20130253186 | HETEROARYLOXYHETEROCYCLYL COMPOUNDS AS PDE10 INHIBITORS - Heteroaryloxyheterocyclyl compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntington's Disease, bipolar disorder, obsessive-compulsive disorder, and the like. | 09-26-2013 |
| 20140213572 | UNSATURATED NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS - Unsaturated nitrogen heterocyclic compounds of formula (I): | 07-31-2014 |
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| 20110307050 | Laser System And Processing Conditions For Manufacturing Bioabsorbable Stents - The present invention involves laser machining polymer substrates to form a stent with laser parameters that minimize damage to the substrate in a surface region adjacent to the machined edge surface. The wavelength and pulse width are selected for this unique application and they can be controlled to minimize the surface modifications (such as voids, cracks which are induced by the laser-material interaction) which contribute to the variation in mechanical properties with distance from the edge surface, bulk mechanical properties, or a combination thereof. | 12-15-2011 |
| 20140155985 | LASER SYSTEM AND PROCESSING CONDITIONS FOR MANUFACTURING BIOABSORBABLE STENTS - The present invention involves laser machining polymer substrates to form a stent with laser parameters that minimize damage to the substrate in a surface region adjacent to the machined edge surface. The wavelength and pulse width are selected for this unique application and they can be controlled to minimize the surface modifications (such as voids, cracks which are induced by the laser-material interaction) which contribute to the variation in mechanical properties with distance from the edge surface, bulk mechanical properties, or a combination thereof. | 06-05-2014 |
| 20140263217 | SHORT PULSE LASER MACHINING OF POLYMERS ENHANCED WITH LIGHT ABSORBERS FOR FABRICATING MEDICAL DEVICES - A method of laser machining a polymer construct to form a stent that includes a bioresorbable polymer and an absorber that increases absorption of laser energy during laser machining. The laser cuts the tubing at least in part by a multiphoton absorption mechanism and the polymer and absorber have a very low absorbance or are transparent to light at the laser wavelength. | 09-18-2014 |
| 20150081000 | BRAIDED SCAFFOLDS - A braided polymeric scaffold, made at least in part from a bioresorbable material is deployed on a catheter that uses a push-pull mechanism to deploy the scaffold. A drug coating is disposed on the scaffold. A plurality of scaffold segments on a catheter is also disclosed. | 03-19-2015 |
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| 20090048076 | Bicycling exercise apparatus - An apparatus permitting a user to perform a simulated bicycling exercise is provided. The design includes a frame and a first mounting point and a second mounting point configured to maintain the frame. A seat is connected to the frame and configured to support the user. A wheel is positioned in association with said frame and pedals configured to interact with the wheel, and the frame is configured to pivot about the first mounting point and second mounting point in response to leaning by the user. Handlebars may be provided that enable further force application and enhance the leaning or pivoting in the bicycle riding simulation experience. | 02-19-2009 |
| 20090170667 | Bicycling exercise apparatus with multiple element load dispersion - An apparatus permitting a user to perform a simulated bicycling exercise is provided. The design includes a frame and a first (lower front) mounting point including a multiple element distributed load arrangement and a second (upper rear) mounting point configured to maintain the frame a first lower front mounting point including a pin defining an axis substantially representing a line joining the second upper rear mounting point and the first lower front mounting point. The design includes a seat, a wheel, and pedals, and the frame is configured to pivot about the axis in response to leaning by the user. Handlebars may be provided that enable force application and enhance the leaning or pivoting in the bicycle riding simulation experience. | 07-02-2009 |
| 20110195820 | Bicycling exercise apparatus - An apparatus permitting a user to perform a simulated bicycling exercise is provided. The design includes a frame and a first mounting point and a second mounting point configured to maintain the frame. A seat is connected to the frame and configured to support the user. A wheel is positioned in association with said frame and pedals configured to interact with the wheel, and the frame is configured to pivot about the first mounting point and second mounting point in response to leaning by the user. Handlebars may be provided that enable further force application and enhance the leaning or pivoting in the bicycle riding simulation experience. | 08-11-2011 |
| 20120108399 | BICYCLING EXERCISE APPARATUS WITH MULTIPLE ELEMENT LOAD DISPERSION - An apparatus permitting a user to perform a simulated bicycling exercise is provided. The design includes a horizontal base, a lower front pivoting point, and user supporting hardware collectively adjoining pedals, a seat configured to support the user, and handlebars, the user supporting hardware provided above the horizontal base and interfacing with the lower front mounting point. The lower front pivoting point and the user supporting hardware include a multiple component resistive element arrangement and collectively define an axis of rotation forming an angle with the horizontal base of 30 to 45 degrees, sloping upward in a rearward direction from the front pivoting point to the user supporting hardware. When the user is seated on the seat and leans in one direction, such leaning causes the user supporting hardware, seat, and handlebars to rotate in the one direction about the axis of rotation. | 05-03-2012 |
| 20130157813 | Bicycling Exercise Apparatus - An apparatus permitting a user to perform a simulated bicycling exercise is provided. The design includes a frame having a head tube, a first upper rear mounting point and a second lower front mounting point configured to maintain the frame, a seat connected to said frame and configured to support the user in a forward facing orientation, a wheel positioned in association with said frame and pedals configured to interact with said wheel, and a stem connected to a handlebar arrangement, the stem passing through the headset collar and connected to a base by a connection arrangement comprising an arm. The frame is configured to pivot about the first upper rear mounting point and second lower front mounting point in response to leaning by the user, causing rotation of the stem within the head tube by movement of the connection arrangement comprising the arm. | 06-20-2013 |
| 20130296139 | BICYCLING EXERCISE APPARATUS WITH MULTIPLE ELEMENT LOAD DISPERSION - An apparatus permitting a user to perform a simulated bicycling exercise is provided. The design includes a base, a frame comprising a head tube, and a lower front pivoting point connected to the base and an upper rear pivoting axial member positioned a fixed distance above the base. The lower front pivoting point and the upper rear pivoting axial member include a multiple component resistive element arrangement and collectively defining an axis of rotation, the axis of rotation forming a fixed angle relative to the base of 30 to 45 degrees, sloping upward in a rearward direction from the front pivoting point to the upper rear pivoting axial member. The design further includes a stem connected to a handlebar arrangement, the stem passing through the head tube and connected to the base by a connection arrangement comprising an arm. | 11-07-2013 |
| 20150080191 | BICYCLING EXERCISE APPARATUS - An apparatus permitting a user to perform a simulated bicycling exercise is provided. The design includes a frame having a head tube, a first upper rear mounting point and a second lower front mounting point configured to maintain the frame, and a stem connected to a handlebar arrangement, the stem passing through the headset collar and connected to a base by a connection arrangement comprising an arm. The frame is configured to pivot about the first upper rear mounting point and second lower front mounting point in response to leaning by the user, causing rotation of the stem within the head tube by movement of the connection arrangement. | 03-19-2015 |
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| 20090268924 | AUTOMOBILE PERSONAL RADIO RECORDER - In one embodiment, an audio recorder is disclosed that interfaces with an automobile radio. The audio recorder includes a radio tuner that receives radio frequency signals and converts the signals to audio output and an audio comparator that compares audio output from the radio tuner with audio output of the automobile radio and tunes the radio tuner until the audio output of the audio tuner is synchronized with the audio output of the automobile radio. An audio storage device is activatable to record the audio output of the radio tuner for later playback. | 10-29-2009 |
| 20090327521 | AUTOMATIC MAPPING OF HUMAN-MEANINGFUL PARAMETERS TO NETWORK-MEANINGFUL PARAMETERS FOR TRAFFIC IMPORTANCE IN HOME NETWORK - A method of automatically discovering home network device capabilities, ranking devices using the capabilities in accordance with ranking heuristics, and implementing traffic policy in accordance with the ranking. | 12-31-2009 |
| 20100005170 | MAPPING HUMAN-MEANINGFUL PARAMETERS TO NETWORK-MEANINGFUL PARAMETERS TO PERMIT USER TO ESTABLISH TRAFFIC IMPORTANCE IN HOME NETWORK - A method of describing highly valued traffic in a home network in terms that are meaningful for a human and that are translated to useful network parameters. | 01-07-2010 |
| 20100057668 | MAPPING HUMAN-MEANINGFUL PARAMETERS TO NETWORK-MEANINGFUL PARAMETERS FOR MEDIA TRANSFORMATION - A method of permitting a user to define preferred and acceptable audio/video experiences in a home network in terms that are meaningful for a human and that are translated to useful content transformation parameters. | 03-04-2010 |
| 20110314083 | MULTICAST AND SYNCHRONIZATION EMULATION FOR CONTENT TRANSFORMED STREAMS - Embodiments of the present disclosure emulate multicast by generating and synchronizing multiple unicasts of a single content in different encoding formats to multiple devices on a shared network. In one embodiment, a method for multicast emulation includes receiving a request to join an active stream containing a media content. The method also includes identifying a position of the active stream from which to start a new unicast stream of the same media content. The method further includes providing the new unicast stream starting from the identified position, where the new unicast stream is in a format independent from the format of the active stream and the new unicast stream is synchronized to the active stream. | 12-22-2011 |
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| 20090083406 | DYNAMIC HOST CONFIGURATION PROTOCOL (DHCP) MESSAGE INTERCEPTION AND MODIFICATION - In an embodiment, a method includes intercepting a configuration message from a first network node addressed to a third network node, and modifying the intercepted configuration message to provide a modified configuration message that includes address information associated with a second network node that is configured to provide bootstrap information for the third node. | 03-26-2009 |
| 20090254976 | CONDITIONAL DATA DELIVERY TO REMOTE DEVICES - In one embodiment a method comprises enrolling a mobile device in a local area network by setting a variable to a mobile device identifier and authenticating the mobile device using a network gateway and the mobile device identifier. A request for data is received from the mobile device and the data is delivered from a service provider to the mobile device. | 10-08-2009 |
| 20110083160 | APPARATUS AND METHOD FOR SECURE CONFIGURATION OF SHARED POWERLINE DEVICES - Client adapter and method simplify security deployment in an EPN, including the shared services electrical power lines of a premises. With direct coupling, piggybacked adapter receives network signals and electrical from EPN-connected first adapter through a shared medium port. An authenticating adapter exchanges security management services and information with supplicant adapter. Two or more adapters may be piggybacked. Piggybacked adapters exchange security management service information without rogue intrusion. Exchanged information, stored, is later used to communicate securely. Defined adjacency (neighborhood) information can be exchanged, and a neighborhood established on an EPN, where one authorized neighbors securely communicate. | 04-07-2011 |
| 20130039213 | SIMULTANEOUS SETUP OF A WIRELESS NETWORK ADAPTER AND A NETWORK HOST DEVICE - A system and method for causing concurrent setup of a wireless network adapter and a network host device. The method involves receiving a request to install either a wireless network adapter or a network host device. If the request is to install the wireless network adapter, then the method further involves detecting that the network host device is not yet installed, and prompting a user to connect to the network host device. Alternatively, if the request is to install the network host device, then the method further involves detecting that the wireless network adapter is not yet installed, and prompting the user to connect to the wireless network adapter. The method also involves causing a connection to be established between the wireless network adapter and the network host device. | 02-14-2013 |
| 20130046899 | IPV6 LAN-SIDE ADDRESS ASSIGNMENT POLICY - Techniques are presented for assigning a network address to a computing device. In one embodiment, a network device such as a router may be responsible for assigning a network address (e.g., an IP address) to a connected computing device. For example, in IPv6, the network device provides the computing device with a 64-bit prefix that the computing device then uses to generate a 128-bit unique IP address. The network device typically receives this prefix from another server located in the WAN. In case of a communication failure with the WAN, the network device may be unable to attain the correct prefix. Instead of assigning a random prefix that may cause a conflict if the computing device uses the incorrect prefix on the WAN, the network device may assign a different IP address using a different communication protocol—e.g., IPv4. The computing device can then use IPv4 to access both the LAN and the WAN without risking a conflict. | 02-21-2013 |
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| 20090318374 | METHODS OF DIAGNOSING AND TREATING MIGRAINE - The present invention provides methods of diagnosing migraine attacks and determining predisposition of an individual to the development of migraine based on sodium level in the cerebrospinal fluid (CSF) and/or brain extracellular fluid. The invention also provides methods of treating migraine, wherein the individual is selected for treatment based in the individual's sodium level in the CSF and/or brain extracellular fluid. The CSF sodium level may be based on the sodium concentration in the saliva. | 12-24-2009 |
| 20110097736 | METHODS OF DETERMINING LEVELS OF FREE AMINO ACID AND DIPEPTIDES AND DIAGNOSING ALZHEIMER'S DISEASES - Provided herein are methods of diagnosing Alzheimer's disease (“AD”) based on characteristic changes of the levels of certain free amino acids or dipeptides (collectively termed as “AD diagnosis markers”) in the body fluid sample of an individual, carnosine synthesis activities in the plasma, and dopamine synthesis activities in the plasma. Also provided are methods of simultaneously determining the levels of at least two free amino acids or dipeptides in the biological fluid sample of an individual. | 04-28-2011 |
| 20120270816 | METHODS OF DIAGNOSING AND TREATING MIGRAINE - The present invention provides methods of diagnosing migraine attacks and determining predisposition of an individual to the development of migraine based on sodium level in the cerebrospinal fluid (CSF) and/or brain extracellular fluid. The invention also provides methods of treating migraine, wherein the individual is selected for treatment based in the individual's sodium level in the CSF and/or brain extracellular fluid. The CSF sodium level may be based on the sodium concentration in the saliva. | 10-25-2012 |
| 20140308753 | METHODS OF DETERMINING LEVELS OF FREE AMINO ACIDS AND DIPEPTIDES AND DIAGNOSING ALZHEIMER'S DISEASE - Provided herein are methods of diagnosing Alzheimer's disease (“AD”) based on characteristic changes of the levels of certain free amino acids or dipeptides (collectively termed as “AD diagnosis markers”) in the body fluid sample of an individual, carnosine synthesis activities in the plasma, and dopamine synthesis activities in the plasma. Also provided are methods of simultaneously determining the levels of at least two free amino acids or dipeptides in the biological fluid sample of an individual. | 10-16-2014 |
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| 20130307693 | SYSTEM AND METHOD FOR REAL TIME DATA ANALYSIS - A system and method for real time data analysis are disclosed. A particular embodiment includes; receiving a plurality of current data streams from a plurality of sensor arrays deployed at a monitored venue; correlating the current data streams with corresponding historical data streams and related data streams; analyzing, by use of a data processor, the data streams to identify patterns of activity, behavior, and/or status occurring at the monitored venue; applying one or more rules of to rule set to the analyzed data streams to determine if an alert should he issued; and dispatching an alert if such alert is determined to be warranted. | 11-21-2013 |
| 20130307972 | SYSTEM AND METHOD FOR PROVIDING A SENSOR AND VIDEO PROTOCOL FOR A REAL TIME SECURITY DATA ACQUISITION AND INTEGRATION SYSTEM - A system and method for providing a sensor and video protocol for a real time security data acquisition and integration system are disclosed. A particular embodiment includes: receiving a data sample; assigning, by use of a data processor, a sample identifier (ID) to the received data sample; recording, into a sensor sample data set, an ID of a sensing device that sourced the data sample; recording, into the sensor sample data set, a time and a location corresponding to when and where the data sample was taken by the sensing device; storing the received data sample into a values section of the sensor sample data set based on a format defined by a sensor fields section of the sensor sample data set; and storing details of the sensing device into a sensor type section of the sensor sample data set. | 11-21-2013 |
| 20130307980 | SYSTEM AND METHOD FOR REAL TIME SECURITY DATA ACQUISITION AND INTEGRATION FROM MOBILE PLATFORMS - A system and method for real time security data acquisition and integration from mobile platforms are disclosed. A particular embodiment includes: deploying a plurality of sensors and video sources in a monitored venue, the plurality of sensors and video sources generating security data in the monitored venue; receiving the security data wirelessly in real time at a real time wireless data integrator positioned adjacent to the monitored venue; establishing a real time wireless data integrator network between at least two real time wireless data integrators; and causing the transfer of the security data to an operations center via a network. | 11-21-2013 |
| 20130307989 | SYSTEM AND METHOD FOR REAL-TIME DATA CAPTURE AND PACKET TRANSMISSION USING A LAYER 2 WIRELESS MESH NETWORK - A system and method for real time security data acquisition and integration from mobile platforms are disclosed. A particular embodiment includes: deploying a plurality of sensors and video sources in a monitored venue, the plurality of sensors and video sources generating security data in the monitored venue; receiving the security data wirelessly in real time at a real time wireless data integrator positioned adjacent to the monitored venue; establishing a real time wireless mesh network including a plurality of real time wireless data integrators, each of the plurality of wireless data integrators being configured to route the security data through the wireless mesh network; and causing the transfer of the security data to an operations center via the wireless mesh network. | 11-21-2013 |
| 20130312043 | SYSTEM AND METHOD FOR SECURITY DATA ACQUISITION AND AGGREGATION ON MOBILE PLATFORMS - A system and method for security data acquisition and aggregation on mobile platforms are disclosed. A particular embodiment includes: providing an edge device data aggregator in a mobile venue; using the edge device data aggregator to receive security data from a plurality of sensors and video sources deployed in the mobile venue; performing at least one processing operation on the security data; and causing the transfer of the processed security data in real time to a real time wireless data integrator positioned outside of the mobile venue. | 11-21-2013 |
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| 20090054463 | Derivatives of urea and related diamines, methods for their manufacture, and uses therefor - The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders related to the function of the calcium sensing receptor. The invention also relates to processes for making such compounds and to intermediates useful in these processes. | 02-26-2009 |
| 20100125062 | PYRIDINE AND PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS - Pyridine and pyrimidine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like. | 05-20-2010 |
| 20100160280 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS - Pyridine and pyrimidine compounds: | 06-24-2010 |
| 20100160327 | Modified Malonate Derivatives - The present invention relates to a novel class of modified malonate derivatives. The modified malonate compounds can be used to treat cancer. The modified malonate compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the modified malonate derivatives and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the modified malonate derivatives in vivo. | 06-24-2010 |
| 20100324046 | 4-CARBOXYBENZYLAMINO DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS - The present invention relates to a novel class of 4-carboxybenzylamino derivatives. The 4-carboxybenzylamino compounds can be used to treat cancer. The 4-carboxybenzylamino compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the 4-carboxybenzylamino derivatives and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the 4-carboxybenzylamino derivatives in vivo. | 12-23-2010 |
| 20110230517 | CALCIUM RECEPTOR MODULATING AGENTS - The present invention relates generally to novel calcimimetic compounds and pharmaceutical compositions comprising them. The invention also relates to methods of treating of diseases or disorders related to the function of the calcium sensing receptor using the compounds represented in Formula (I). Where Cy | 09-22-2011 |
| 20130137690 | 4-CARBOXYBENZYLAMINO DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS - The present invention relates to a novel class of 4-carboxybenzylamino derivatives. The 4-carboxybenzylamino compounds can be used to treat cancer. The 4-carboxybenzylamino compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the 4-carboxybenzylamino derivatives and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the 4-carboxybenzylamino derivatives in vivo. | 05-30-2013 |
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| 20080221101 | Calcium receptor modulating agents - The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders related to the function of the calcium sensing receptor. The invention also relates to processes for making such compounds and to intermediates useful in these processes. | 09-11-2008 |
| 20110178133 | CALCIUM RECEPTOR MODULATING AGENTS - The present invention relates generally to novel calcimimetic compounds and pharmaceutical compositions comprising them. The invention also relates to methods of treating of diseases or disorders related to the function of the calcium sensing receptor using the compounds represented in Formula I. | 07-21-2011 |
| 20110306590 | ARYL- AND HETEROARYL- NITROGEN-HETEROCYCLIC COMPOUNDS AS PDE10 INHIBITORS - Aryl- and heteroaryl-nitrogen heterocyclic compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntington's Disease, bipolar disorder, obsessive-compulsive disorder, and the like. | 12-15-2011 |
| 20110306591 | HETEROARYLOXYCARBOCYCLYL COMPOUNDS AS PDE10 INHIBITORS - Heteroaryloxycarbocyclyl compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntington's Disease, bipolar disorder, obsessive-compulsive disorder, and the like. | 12-15-2011 |
| 20130079325 | PYRIDINE AND PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS - Pyridine and pyrimidine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like. | 03-28-2013 |
| 20140107109 | AMINO-DIHYDROTHIAZINE AND AMINO-DIOXIDO DIHYDROTHIAZINE COMPOUNDS AS BETA-SECRETASE ANTAGONISTS AND METHODS OF USE - The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I: | 04-17-2014 |
| 20140275058 | PERFLUORINATED CYCLOPROPYL FUSED 1,3-OXAZIN-2-AMINE COMPOUNDS AS BETA-SECRETASE INHIBITORS AND METHODS OF USE - The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I: | 09-18-2014 |
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| 20120000528 | METHOD OF FABRICATING A SOLAR CELL WITH A TUNNEL DIELECTRIC LAYER - Methods of fabricating solar cells with tunnel dielectric layers are described. Solar cells with tunnel dielectric layers are also described. | 01-05-2012 |
| 20130078758 | METHOD OF FABRICATING A SOLAR CELL WITH A TUNNEL DIELECTRIC LAYER - Methods of fabricating solar cells with tunnel dielectric layers are described. Solar cells with tunnel dielectric layers are also described. | 03-28-2013 |
| 20130247967 | GASEOUS OZONE (O3) TREATMENT FOR SOLAR CELL FABRICATION - Methods of fabricating solar cells and apparatuses for fabricating solar cells are described. In an example, a method of fabricating a solar cell includes treating a light-receiving surface of a substrate with a gaseous ozone (O | 09-26-2013 |
| 20140134788 | METHOD OF FABRICATING A SOLAR CELL WITH A TUNNEL DIELECTRIC LAYER - Method of fabricating solar cells with tunnel dielectric layers are described. Solar cells with tunnel dielectric layers are also described. | 05-15-2014 |
| 20140273331 | METHODS FOR WET CHEMISTRY POLISHING FOR IMPROVED LOW VISCOSITY PRINTING IN SOLAR CELL FABRICATION - A method of fabricating a solar cell is disclosed. The method includes forming a polished surface on a silicon substrate and forming a first flowable matrix in an interdigitated pattern on the polished surface, where the polished surface allows the first flowable matrix to form an interdigitated pattern comprising features of uniform thickness and width. In an embodiment, the method includes forming the silicon substrate using a method such as, but not limited to, of diamond wire or slurry wafering processes. In another embodiment, the method includes forming the polished surface on the silicon substrate using a chemical etchant such as, but not limited to, sulfuric acid (H | 09-18-2014 |
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| 20120180979 | Computer Cooling System And Method of Use - A reliable, leak-tolerant liquid cooling system with a backup air-cooling system for computers is provided. The system may use a vacuum pump and a liquid pump and/or an air compressor in combination to provide negative fluid pressure so that liquid does not leak out of the system near electrical components. Alternatively, the system can use a single vacuum pump and a valve assembly to circulate coolant. The system distributes flow and pressure with a series of pressure regulating valves so that an array of computers can be serviced by a single cooling system. The system provides both air and liquid cooling so that if the liquid cooling system does not provide adequate cooling, the air cooling system will be automatically activated. The heat may be removed from the building efficiently with a cooling tower. | 07-19-2012 |
| 20140130382 | Pneumatic Excavation System And Method Of Use - An excavation system employing a high-pressure pulsed air jet in combination with a low-pressure high velocity blower for excavating improvised explosive devices or other buried objects. The excavation system may also be employed to operate a pneumatic tool such as a cut-off tool or a chisel. The high velocity blower may incorporate a bifurcated fan duct having two air outlets. The system may include a pressure control module for regulating the from a high-pressure air source to an evacuation valve. The evacuation valve employs first and second valves where the second valve controls the operation of the first valve. | 05-15-2014 |
| 20140130383 | Pneumatic Excavation System And Method Of Use - An excavation system employing a high-pressure pulsed air jet in combination with a low-pressure high velocity blower for excavating improvised explosive devices or other buried objects. The excavation system may also be employed to operate a pneumatic tool such as a cut-off tool or a chisel. The high velocity blower may incorporate a bifurcated fan duct having two air outlets. The system may include a pressure control module for regulating the from a high-pressure air source to an evacuation valve. The evacuation valve employs first and second valves where the second valve controls the operation of the first valve. | 05-15-2014 |
| 20140190660 | Vacuum Pumped Liquid Cooling System for Computers - A reliable, leak tolerant liquid cooling system with a backup air-cooling system for computers is provided. The system may use a vacuum pump and a liquid pump in combination to provide negative fluid pressure so that liquid does not leak out of the system near electrical components. The system distributes flow and pressure with a series of pressure regulating valves so that an array of computers can be serviced by a single cooling system. The system provides both air and liquid cooling so that if the liquid cooling system does not provide adequate cooling, the air cooling system will be automatically activated. A connector system is provided to automatically evacuate the liquid from the heat exchangers before they are disconnected. | 07-10-2014 |
| 20140373933 | No Drip Hot Swap Connector And Method of Use - A connector for use in a negative pressure coolant system is disclosed. The connector connects coolant system circulating to an electrical component thereby allowing the coolant to circulate through the electrical component. The connector is made up of two components, a component side connector and a pump side connector, and can be in three positions: disengaged, semi-engaged and fully-engaged. An electrical component can be drained of its coolant while the connector is shifted from the fully-engaged position, to the semi-engaged position and to the disengaged position. This can be accomplished without shutting down the negative pressure coolant system, thus allowing a particular electrical component to be disconnected without affecting the cooling efficiency of other electrical components connected to the system. Because the coolant is drained, it will not spill on the electrical component and cause damage. | 12-25-2014 |
| Patent application number | Description | Published |
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| 20080302516 | Compressor Cooling System and Method of Use - A compressor cooling system for an air compressor includes an air compressor including an external surface; an enclosure for enclosing the air compressor inside the enclosure; an air passage formed on the inside of the enclosure between the enclosure and the external surface of the air compressor; multiple holes in the enclosure; and a negative pressure source coupled to the air passage for drawing air through the multiple holes and into the enclosure for cooling the compressor. | 12-11-2008 |
| 20080302596 | Diaphragm Muffler and Method of Use - A diaphragm muffler for quiet operation of a compressor imparting an above atmospheric pressure stream and a below atmospheric pressure stream. The diaphragm muffler including a diaphragm pressure chamber receiving the above atmospheric pressure stream; a diaphragm vacuum chamber receiving the below atmospheric pressure stream; and a flexible diaphragm dividing the diaphragm pressure chamber receiving the above atmospheric pressure stream from the diaphragm vacuum chamber receiving the below atmospheric pressure stream, whereby the above atmospheric pressure stream and the below atmospheric pressure stream cancel each other out via the flexible diaphragm. | 12-11-2008 |
| 20080304980 | Compressor Vibration Isolation Mount and Method of Use - A compressor vibration isolation mount for isolating the vibrations of a compressor from the rest of a structure includes at least one frame; and at least one gimbal coupling the compressor to the at least one frame for partial rotation about at least one primary axis of rotation. | 12-11-2008 |
| 20090257888 | MULTIPLE CHAMBER PUMP AND METHOD - Disclosed is a pneumatically powered high-pressure and lightweight fluid pump. The pump is useful for pumping fuel for liquid rocket engines and for transferring liquids from one space vehicle to another. During operation of the pump, liquid is drained from a tank into a pump chamber and the chamber is then pressurized to deliver fluid. The chamber is then refilled from the main tank. An auxiliary chamber supplies fuel while the main chamber is being filled, thereby a steady stream is delivered from the pump. The auxiliary chamber is refilled from the tank while the main chamber is delivering fluid. In order to transfer fluid from the tank to the pump chamber, the pressure in the pump chamber is maintained at a pressure higher than the vapor pressure of the fluid being pumped but lower than the pressure in the tank. | 10-15-2009 |
| 20110253147 | BREATHING APPARATUS - A breathing apparatus includes a supply tube configured to provide a supply of air. A first and second nasal interface each include a generally spherical member having a respective projection configured to be at least partially received within a respective nasal passage of a user, and are independently movable relative to the housing. A valve is disposed between the fluid chamber and an exhaust passage for selectively allowing air to be exhausted from the fluid chamber via the exhaust passage. A diaphragm, coupled to a bias chamber, is also coupled to the valve for moving the valve between the open position and the closed position. Bias pressure within the bias chamber is regulated, at least in part, by a loading fluid impedance and a venting fluid impedance. | 10-20-2011 |
| Patent application number | Description | Published |
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| 20080272200 | Rotary sprayer for a fluid delivery device - A rotary sprayer and method for spraying an inner surface of an enclosure, such as a toilet bowl, with a fluid are disclosed. The rotary sprayer includes a clip and a rotating nozzle. The clip includes a fluid inlet and an arm having a distal end section. The nozzle includes a circular deflection plate, and a pair of spaced apart walls extending away from a surface of the deflection plate. The walls define a channel on the surface of the deflection plate. A passageway is in fluid communication with the channel and an end space between the walls. The fluid inlet is positioned in the end space and a spindle of the nozzle is mounted to the distal end section of the arm. Fluid exiting the fluid inlet flows through the passageway and the channel and contacts an inner surface of at least one of the walls to rotate the nozzle and spray the inner surface wall of the enclosure with the fluid. | 11-06-2008 |
| 20090044372 | Handheld Portable Devices for Touchless Particulate Matter Removal - Handheld portable devices for dislodging and capturing particulate matter that has accumulated on various surfaces or structures are provided. The devices create opposing airflows that can intimately interface with each other during use. A vacuum airflow is drawn into the device, defining a vacuum affected zone upon the surface being cleaned. A high pressure airflow is emitted that penetrates through or passes adjacent to the opposing vacuum airflow and contacts the surface being cleaned, dislodging particulate matter therefrom. The high pressure airflow can be emitted from multiple nozzles as a series of airflow bursts that discretely contact the surface being cleaned. The configuration of each nozzle, as well as the overall arrangement and positions of all the nozzles together, are selected to impart the desired particulate matter dislodging characteristics to the device. | 02-19-2009 |
| 20100089058 | Combustion Powered Hydroelectric Sequential Turbines - This invention is a method to extract energy from a pressurized gas in the case that the gas may be unsuitable for use in a gas turbine. The system is a gas powered liquid pump. The system expands the gas against a liquid such as water and the water then flows through a series of liquid turbines to generate power. As the gas expands the pressure decreases. The water is initially directed to a turbine designed to work efficiently with high-pressure water, and then the water is redirected to another turbine which is designed to work efficiently with lower pressure water. As the pressure of the gas and the water decreases, the turbine which most efficient for extracting the energy at a given pressure is used to extract the energy from the stream of pressurized water | 04-15-2010 |
| 20110277270 | PORTABLE DEVICES FOR TOUGHLESS PARTICULATE MATTER REMOVAL - Portable devices for dislodging and/or capturing particulate matter that has accumulated on various surfaces or structures are provided. The devices include a body segment and a nose segment extending away therefrom. A high-pressure assembly generates a high-pressure airflow that is directed to a nozzle assembly in the nose segment. From the nozzle assembly, the high-pressure airflow can be emitted from multiple nozzles as a series of airflow bursts that discretely contact the surface from which the particulate matter is being dislodged. The configuration of each nozzle, as well as the overall arrangement and positions of all the nozzles together, is selected to impart the desired particulate matter dislodging characteristics to the device, and the device may incorporate a vacuum airflow to remove the particulate matter after such matter has been dislodged. | 11-17-2011 |
| 20130185966 | Pulsed Supersonic Jet with Local High Speed Valve - A pulsed supersonic jet excavator uses a short duration blast of air to excavate using a minimum amount of air and a minimum reaction force. This device uses a fast acting valve to create a jet of air that lasts about as long as it takes to develop. The result is a device that works much more efficiently than existing air jet excavators. This device can be mounted on a small robot and allow it to dig, whereas a normal backhoe type excavator would just lift the robot when attempting to dig in packed earth. | 07-25-2013 |
