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| 20080279871 | Immunogenic composition - The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers. | 11-13-2008 |
| 20090142770 | Hair Follicle Pharmacodynamic Assay for Telomerase Activity - The invention is directed to methods for determining the efficacy of treatment with telomerase modulators in mammals by the analysis of the level of telomerase reverse transcriptase activity in mammalian hair follicle cells. | 06-04-2009 |
| 20090269739 | Kit for detection of telomerase reverse transcriptase nucleic acids - The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers. | 10-29-2009 |
| 20100292197 | Compositions and Methods for Increasing Telomerase Activity - The present invention relates to methods and compositions for increasing telomerase activity in cells. Such compositions include pharmaceutical formulations. The methods and compositions are useful for treating diseases subject to treatment by an increase in telomerase activity in cells or tissue of a patient. They are also useful for enhancing replicative capacity of cells in culture, as in ex vivo cell therapy and for enhancing proliferation of stem and progenitor cells. | 11-18-2010 |
| 20110263685 | Method for Identification of Sensitivity of a Patient to Telomerase Inhibition Therapy - The invention provides methods for determining the susceptibility of cancer patients to developing adverse reactions if treated with a telomerase inhibitor drug by measurement of telomere length in appropriate cells of the patient prior to initiation of the telomerase inhibitor treatment. | 10-27-2011 |
| 20110318832 | Human Telomerase Catalytic Subunit - The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers. | 12-29-2011 |
| 20120070842 | Assay for Telomerase Activity Using Microfluidic Device - Methods for determining the level of telomerase reverse transcriptase activity in mammalian cells are disclosed. A preferred measuring device is a microfluidic device that includes a spectrophotometer, a fluorescent detector, a fluorescence polarization detector or a scintillation counting device. | 03-22-2012 |
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| 20110071095 | Compositions and Methods for Increasing Telomerase Activity - The present invention relates to methods and compositions for increasing telomerase activity in cells. Such compositions include pharmaceutical, including topical, and nutraceutical formulations. The methods and compositions are useful for treating diseases subject to treatment by an increase in telomerase activity in cells or tissue of a patient, such as, for example, HIV infection, various degenerative diseases, and acute or chronic skin ailments. They are also useful for enhancing replicative capacity of cells in culture, as in ex vivo cell therapy and proliferation of stem cells. | 03-24-2011 |
| 20140088055 | COMPOSITIONS AND METHODS FOR INCREASING TELOMERASE ACTIVITY - The present invention relates to methods and compositions for increasing telomerase activity in cells. Such compositions include pharmaceutical formulations. The methods and compositions are useful for treating diseases subject to treatment by an increase in telomerase activity in cells or tissue of a patient. They are also useful for enhancing replicative capacity of cells in culture, as in ex vivo cell therapy and for enhancing proliferation of stem and progenitor cells. | 03-27-2014 |
| 20150093455 | COMPOSITIONS AND METHODS FOR INCREASING TELOMERASE ACTIVITY - The present invention relates to methods and compositions for increasing telomerase activity in cells. Such compositions include pharmaceutical, including topical, and nutraceutical formulations. The methods and compositions are useful for treating diseases subject to treatment by an increase in telomerase activity in cells or tissue of a patient, such as, for example, HIV infection, various degenerative diseases, and acute or chronic skin ailments. They are also useful for enhancing replicative capacity of cells in culture, as in ex vivo cell therapy and proliferation of stem cells. | 04-02-2015 |
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| 20110126898 | SOLAR CELL CONTACT FORMATION USING LASER ABLATION - The formation of solar cell contacts using a laser is described. A method of fabricating a back-contact solar cell includes forming a poly-crystalline material layer above a single-crystalline substrate. The method also includes forming a dielectric material stack above the poly-crystalline material layer. The method also includes forming, by laser ablation, a plurality of contacts holes in the dielectric material stack, each of the contact holes exposing a portion of the poly-crystalline material layer; and forming conductive contacts in the plurality of contact holes. | 06-02-2011 |
| 20110300665 | Ablation Of Film Stacks In Solar Cell Fabrication Processes - A dielectric film stack of a solar cell is ablated using a laser. The dielectric film stack includes a layer that is absorptive in a wavelength of operation of the laser source. The laser source, which fires laser pulses at a pulse repetition rate, is configured to ablate the film stack to expose an underlying layer of material. The laser source may be configured to fire a burst of two laser pulses or a single temporally asymmetric laser pulse within a single pulse repetition to achieve complete ablation in a single step. | 12-08-2011 |
| 20120003788 | High Throughput Solar Cell Ablation System - A solar cell is formed using a solar cell ablation system. The ablation system includes a single laser source and several laser scanners. The laser scanners include a master laser scanner, with the rest of the laser scanners being slaved to the master laser scanner. A laser beam from the laser source is split into several laser beams, with the laser beams being scanned onto corresponding wafers using the laser scanners in accordance with one or more patterns. The laser beams may be scanned on the wafers using the same or different power levels of the laser source. | 01-05-2012 |
| 20120204926 | PROCESS AND STRUCTURES FOR FABRICATION OF SOLAR CELLS - Contact holes of solar cells are formed by laser ablation to accommodate various solar cell designs. Use of a laser to form the contact holes is facilitated by replacing films formed on the diffusion regions with a film that has substantially uniform thickness. Contact holes may be formed to deep diffusion regions to increase the laser ablation process margins. The laser configuration may be tailored to form contact holes through dielectric films of varying thicknesses. | 08-16-2012 |
| 20120312791 | HIGH THROUGHPUT SOLAR CELL ABLATION SYSTEM - A solar cell is formed using a solar cell ablation system. The ablation system includes a single laser source and several laser scanners. The laser scanners include a master laser scanner, with the rest of the laser scanners being slaved to the master laser scanner. A laser beam from the laser source is split into several laser beams, with the laser beams being scanned onto corresponding wafers using the laser scanners in accordance with one or more patterns. The laser beams may be scanned on the wafers using the same or different power levels of the laser source. | 12-13-2012 |
| 20130065357 | SOLAR CELL CONTACT FORMATION USING LASER ABLATION - The formation of solar cell contacts using a laser is described. A method of fabricating a back-contact solar cell includes forming a poly-crystalline material layer above a single-crystalline substrate. The method also includes forming a dielectric material stack above the poly-crystalline material layer. The method also includes forming, by laser ablation, a plurality of contacts holes in the dielectric material stack, each of the contact holes exposing a portion of the poly-crystalline material layer; and forming conductive contacts in the plurality of contact holes. | 03-14-2013 |
| 20130196464 | LASER SYSTEM WITH MULTIPLE LASER PULSES FOR FABRICATION OF SOLAR CELLS - A laser system with multiple laser pulses for removing material from a solar cell being fabricated. The laser system includes a single pulse laser source and a multi-pulse generator. The multi-pulse generator receives a single pulse laser beam from the single pulse laser source and converts the single pulse laser beam into a multi-pulse laser beam. A laser scanner scans the multi-pulse laser beam onto the solar cell to remove material from the solar cell. | 08-01-2013 |
| 20140096824 | PROCESS AND STRUCTURES FOR FABRICATION OF SOLAR CELLS - Contact holes of solar cells are formed by laser ablation to accommodate various solar cell designs. Use of a laser to form the contact holes is facilitated by replacing films formed on the diffusion regions with a film that has substantially uniform thickness. Contact holes may be formed to deep diffusion regions to increase the laser ablation process margins. The laser configuration may be tailored to form contact holes through dielectric films of varying thicknesses. | 04-10-2014 |
| 20140134787 | SOLAR CELL CONTACT FORMATION USING LASER ABLATION - The formation of solar cell contacts using a laser is described. A method of fabricating a back-contact solar cell includes forming a poly-crystalline material layer above a single-crystalline substrate. The method also includes forming a dielectric material stack above the poly-crystalline material layer. The method also includes forming, by laser ablation, a plurality of contacts holes in the dielectric material stack, each of the contact holes exposing a portion of the poly-crystalline material layer; and forming conductive contacts in the plurality of contact holes. | 05-15-2014 |
| 20140174519 | METAL-FOIL-ASSISTED FABRICATION OF THIN-SILICON SOLAR CELL - One embodiment relates to a method of fabricating a solar cell. A silicon lamina is cleaved from the silicon substrate. The backside of the silicon lamina includes the P-type and N-type doped regions. A metal foil is attached to the backside of the silicon lamina. The metal foil may be used advantageously as a built-in carrier for handling the silicon lamina during processing of a frontside of the silicon lamina. Another embodiment relates to a solar cell that includes a silicon lamina having P-type and N-type doped regions on the backside. A metal foil is adhered to the backside of the lamina, and there are contacts formed between the metal foil and the doped regions. Other embodiments, aspects and features are also disclosed. | 06-26-2014 |
| 20140326308 | SOLAR CELL CONTACT FORMATION USING LASER ABLATION - The formation of solar cell contacts using a laser is described. A method of fabricating a back-contact solar cell includes forming a poly-crystalline material layer above a single-crystalline substrate. The method also includes forming a dielectric material stack above the poly-crystalline material layer. The method also includes forming, by laser ablation, a plurality of contacts holes in the dielectric material stack, each of the contact holes exposing a portion of the poly-crystalline material layer; and forming conductive contacts in the plurality of contact holes. | 11-06-2014 |
| 20150108692 | HIGH THROUGHPUT LASER PROCESSING - A solar cell is formed using a solar cell ablation system. The ablation system includes a single laser source and several laser scanners. The laser scanners include a master laser scanner, with the rest of the laser scanners being slaved to the master laser scanner. A laser beam from the laser source is split into several laser beams, with the laser beams being scanned onto corresponding wafers using the laser scanners in accordance with one or more patterns. The laser beams may be scanned on the wafers using the same or different power levels of the laser source. | 04-23-2015 |
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| 20110250092 | Inlaid optical material and method of manufacture - An optical material is inlaid into a supporting substrate, with the top surface of the optical material flush with the top surface of the substrate, wherein the optical element is used to shape a beam of light travelling substantially parallel to the top surface of the substrate, but with the central axis of the beam below the top surface of the substrate. The optical elements serve to shape the beam of light for delivery to or from a microfabricated structure within the device. | 10-13-2011 |
| 20120080762 | Plating process and apparatus for through wafer features - A method for forming through features in a substrate uses a seed layer deposited over a first substrate, and a second substrate bonded to the seed layer. The features may be formed in the first substrate, by plating a conductive filler material onto the seed layer. The first substrate and the second substrate may then be bonded to a third substrate, and the second substrate is removed, leaving through features and first substrate adhered to the third substrate. The through features may provide at least one of electrical access and motion to a plurality of devices formed on the third substrate, or may impart movement to a moveable feature on the first substrate, wherein the third substrate supports the first substrate after removal of the second substrate. | 04-05-2012 |
| 20120164718 | Removable/disposable apparatus for MEMS particle sorting device - A micromechanical particle sorting system uses a removable/disposable apparatus which may include a compressible device, a filter apparatus and a cell sorter chip assembly. The chip assembly may include a tubing strain relief manifold and a microfabricated cell sorting chip. The chip assembly may be detachable from the filter apparatus in order to mount the MEMS particle sorting chip adjacent to a force-generating apparatus which resides with the particle sorting system. A disturbance device installed in the particle sorting system may interact with a transducer on the removable/disposable apparatus to reduce clogging of the flow through the system. Using this removable/disposable apparatus, when the sample is changed, the entire apparatus can be thrown away with minimal expense and system down time. | 06-28-2012 |
| 20120190104 | MEMS Particle sorting actuator and method of manufacturing - A MEMS-based system and a method are described for separating a target particle from the remainder of a fluid stream. The system makes use of a unique, microfabricated movable structure formed on a substrate, which moves in a rotary fashion about one or more fixed points, which are all located on one side of the axis of motion. The movable structure is actuated by a separate force-generating apparatus, which is entirely separate from the movable structure formed on its substrate. This allows the movable structure to be entirely submerged in the sample fluid. | 07-26-2012 |
| 20120190105 | Cartridge for MEMS particle sorting system - A disposable cartridge is described which is compatible with a MEMS particle sorting device. The disposable cartridge may include passageways which connect fluid reservoirs in the cartridge with corresponding microfluidic passageways on the MEMS chip. A flexible gasket may prevent leakages and allow the fluid to cross the gasket barrier through a plurality of holes in the gasket. Vents and septums may also be included to allow air to escape and fluids to be inserted by hypodermic needle. A MEMS-based particle sorting system using the disposable cartridge is also described. | 07-26-2012 |
| 20120255373 | Multistage cartridge for MEMS particle storing system - A disposable cartridge is described which is equipped with a plurality of microfabricated particle sorting structures. The disposable cartridge may include passageways which connect fluid reservoirs in the cartridge with corresponding microfluidic passageways on the particle sorting structure. A flexible gasket may prevent leakages and allow the fluid to cross the gasket barrier through a plurality of holes in the gasket, allowing fluid to be transferred from the reservoirs to the microfabricated particle sorting structures. The plurality of particle sorting structures may be arranged in the disposable cartridge in order to perform multiple separation operations, such as a sequential or parallel sorting operation. | 10-11-2012 |
| 20150031120 | MEMS PARTICLE SORTING ACTUATOR AND METHOD OF MANUFACTURE - A MEMS-based system and a method are described for separating a target particle from the remainder of a fluid stream. The system makes use of a unique, microfabricated movable structure formed on a substrate, which moves in a rotary fashion about one or more fixed points, which are all located on one side of the axis of motion. The movable structure is actuated by a separate force-generating apparatus, which is entirely separate from the movable structure formed on its substrate. This allows the movable structure to be entirely submerged in the sample fluid. | 01-29-2015 |
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| 20090194344 | Single Layer Mutual Capacitance Sensing Systems, Device, Components and Methods - According to one embodiment, there is provided a mutual capacitance sensing system comprising at least one substrate comprising an electrode array mounting surface. A plurality of drive electrodes are disposed in a first plurality of rows or columns positioned upon the electrode array mounting surface, where the drive electrodes in each row or column are electrically connected to one another. A plurality of sense electrodes are disposed in a second plurality of rows or columns positioned upon the electrode array mounting surface that is substantially perpendicular to the first plurality of rows or columns, and the sense electrodes in each column are electrically connected to one another. The sense and drive electrodes form an array disposed substantially in a single plane that is configured to permit at least one location corresponding to at least one finger placed in proximity thereto to be detected thereby. | 08-06-2009 |
| 20100026655 | Capacitive Touchscreen or Touchpad for Finger or Stylus - According to one embodiment, there is provided a mutual capacitance touchscreen or touchpad having combined finger navigation and stylus navigation and/or character entry capabilities. First and second pluralities of sense and drive electrodes are disposed in or on upper and lower substrates. The sense and drive electrodes form an array disposed substantially in two opposing planes that are configured to permit at least one location corresponding to a finger or stylus placed in proximity thereto to be detected thereby. The upper substrate is deflectable towards the lower substrate when the stylus is pressed downwardly thereagainst. | 02-04-2010 |
| 20110134050 | FABRICATION OF TOUCH SENSOR PANEL USING LASER ABLATION - Fabrication of a touch sensor panel using laser ablation is disclosed. The fabricated touch sensor panel can have its touch sensors formed on an under surface of its cover substrate. A fabrication method can include depositing a conductive layer onto a substrate, depositing a dielectric material onto the conductive layer, ablating the conductive layer to define different regions for the touch sensors, and depositing a conductive material on the dielectric material. Another fabrication method can include sputtering a conductive material onto a substrate at discrete locations on the substrate, printing a dielectric material on the conductive material at the discrete locations, depositing a conductive layer over the substrate, and selectively ablating the conductive layer at the discrete locations to define different regions for the touch sensors. The touch sensor panel can be incorporated into a mobile telephone, a digital media player, or a personal computer. | 06-09-2011 |
| 20120026099 | Fabrication of Touch Sensor Panel Using Laser Ablation - Fabrication of a touch sensor panel using laser ablation is disclosed. The fabricated touch sensor panel can have its touch sensors formed from conductive layers disposed on a surface such as an undersurface of the panel's cover substrate. A fabrication method can include ablating a first conductive layer to define the first part of the touch sensors and then ablating a second conductive layer proximate to the first conductive layer to define the second part of the touch sensors. The touch sensor panel can be incorporated into a mobile telephone, a digital media player, or a personal computer. | 02-02-2012 |
| 20120026123 | Compensation for Capacitance Change in Touch Sensing Device - This relates to compensation for undesirable capacitance changes in a touch sensing device, where the capacitance changes are not indicative of a touch at the device. The touch sensing device can include a touch sensor panel having touch sensors for sensing a touch at the panel, a flexible circuit for transmitting the sensed touch signal from the panel, and a touch controller for receiving and processing the transmitted signal. To compensate for the capacitance changes, the touch sensing device can include one or more reference conductive traces decoupled from touch sensors of the device to measure non-touch capacitances in the device. The touch sensing device can then adjust a touch signal from the touch sensors using the non-touch capacitance measurements to substantially reduce or eliminate the non-touch capacitances from the signal. | 02-02-2012 |
| 20120327040 | IDENTIFIABLE STYLUS - A stylus is disclosed. The stylus includes a shaft; a conductive tip at a distal end of the shaft; and control circuitry coupled to the conductive tip and configured to generate a modulated signal at the conductive tip to identify the stylus. The stylus can also include a switch coupled between the conductive tip and the shaft. The control circuitry can be further configured to control the switch to modulate a conductive path between the conductive tip and the shaft to generate the modulated signal. | 12-27-2012 |
| 20120327041 | ACTIVE STYLUS - An active stylus is disclosed. The stylus includes an electrode at a tip of the stylus; and powered circuitry coupled to the electrode and configured for capacitively coupling the electrode with a capacitive touch sensor panel. The powered circuitry can further include drive circuitry configured to output a drive voltage at the electrode and/or sense circuitry configured to sense a voltage received at the electrode. | 12-27-2012 |
| 20120327042 | STYLUS ORIENTATION DETECTION - Stylus orientation detection is disclosed. In an example, the orientation of a stylus relative to a contacting surface, e.g., a touch panel, can be detected by detecting a capacitance at one or more locations on the stylus relative to the surface, and then using the capacitance(s) to determine the orientation of the stylus relative to the surface. In another example, the orientation of a stylus relative to a contacting surface, e.g., a touch panel, can be detected by first detecting the orientation of the stylus relative to a reference, detecting the orientation of the contacting surface relative to the reference, and then calculating the orientation of the stylus relative to the contacting surface using the two detected orientations. | 12-27-2012 |
| 20120331546 | INTELLIGENT STYLUS - An intelligent stylus is disclosed. The stylus can provide a stylus condition in addition to a touch input. The stylus architecture can include multiple sensors to sense information indicative of the stylus condition, a microcontroller to determine the stylus condition based on the sensed information, and a transmitter to transmit the determined condition to a corresponding touch sensitive device so as to cause some action based on the condition. | 12-27-2012 |
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| 20140028607 | Device for Digital Communication Through Capacitive Coupling - A computing device configured to communicate with an input device. The computing device includes a processor, a touch interface, such as a touch screen, and a receiving unit. The touch interface is configured to detect an input signal corresponding to an object approaching or contacting a surface. The receiving unit is configured to receive, through the touch interface, at least one input signal from the input device, and the receiving unit amplifies the at least one input signal creating at least one amplified input signal. Additionally, at least one of the processor or the receiving unit analyzes the at least one amplified input signal and creates at least one output digital signal corresponding to the at least one input signal. | 01-30-2014 |
| 20140085247 | Force Sensing Using Dual-Layer Cover Glass with Gel Adhesive and Capacitive Sensing - A touch device including a force sensor disposed between capacitive sensing structures, so both touch and force sensing occur capacitively using device drivers in rows and columns. A dual-layer cover glass, with gel adhesive separating first and second CG layers, so capacitive sensing between the first and second CG layers can determine both touch locations and applied force. The first and second CG layers include a compressible material having a Poisson's ratio of less than approximately 0.48, the force sensor being embedded therein, or disposed between the first and second CG layers. Applied force is detected using capacitive detection of depression of the first CG layer. Depression is responsive to compressible features smaller than optical wavelengths, so those features are substantially invisible to users. Alternatively, the compressible features may be large enough to be seen by a user, but made substantially invisible through the use of a fluid or other element filling spaces between the features. Such a fluid may have an index of refraction equal to, or nearly equal to, the index of refraction of the compressible features. | 03-27-2014 |
| 20140085253 | Force Sensing Using Dual-Layer Cover Glass with Gel Adhesive and Capacitive Sensing - A touch device including a force sensor disposed between capacitive sensing structures, so both touch and force sensing occur capacitively using device drivers in rows and columns. A dual-layer cover glass, with gel adhesive separating first and second CG layers, so capacitive sensing between the first and second CG layers can determine both touch locations and applied force. The first and second CG layers include a compressible material having a Poisson's ratio of less than approximately 0.48, the force sensor being embedded therein, or disposed between the first and second CG layers. Applied force is detected using capacitive detection of depression of the first CG layer. Depression is responsive to compressible features smaller than optical wavelengths, so those features are substantially invisible to users. Alternatively, the compressible features may be large enough to be seen by a user, but made substantially invisible through the use of a fluid or other element filling spaces between the features. Such a fluid may have an index of refraction equal to, or nearly equal to, the index of refraction of the compressible features. | 03-27-2014 |
| 20150091708 | Remote Control Configuration using a Remote Control Profile - Utilizing remote control profile information for configuration of a remote control device. A media processing device may store a remote control profile, locally or on a server accessible via a wide area network, which may include information for configuring a remote control device to utilize one or more wireless remote control commands for controlling the media processing device. The media processing device may also detect one or more wireless remote control commands for controlling one or more other electronic devices and update the remote control profile to include information for configuring a remote control device to utilize those commands. It may be determined to configure a remote control device according to the remote control profile based at least in part on proximity of the remote control device to the media processing device. The remote control device may then be configured according to the remote control profile. | 04-02-2015 |
| 20150103049 | ACTIVE STYLUS - An active stylus is disclosed. The stylus includes an electrode at a tip of the stylus; and powered circuitry coupled to the electrode and configured for capacitively coupling the electrode with a capacitive touch sensor panel. The powered circuitry can further include drive circuitry configured to output a drive voltage at the electrode and/or sense circuitry configured to sense a voltage received at the electrode. | 04-16-2015 |
