Hardee, US
Donald Ray Hardee, Sumter, SC US
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20150311683 | ELECTRICAL SYSTEM, AND SUPPORT ASSEMBLY AND METHOD OF RACKING ELECTRICAL SWITCHING APPARATUS THEREFOR - A support assembly is for an electrical system including an electrical enclosure, an electrical switching apparatus removably disposed in the electrical enclosure, and a plate member coupled to the electrical switching apparatus. The plate member includes a distal portion facing away from the electrical enclosure. The electrical switching apparatus includes an operating handle extending through the distal portion. The support assembly includes a base assembly. The base assembly includes a base. The support assembly further includes a number of brace assemblies each coupled to the base and structured to be coupled to the distal portion of the plate member. | 10-29-2015 |
Glenn C. Hardee, Amelia, VA US
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20110185583 | MULTIPURPOSE TOOL FOR MARKING A SUBSTRATE - Described herein is a multipurpose tool used for marking a substrate. The tool includes at least first and second generally planar layers. The first layer includes first and second edges for guiding a marking device, and third and fourth edges for abutting a first surface of the substrate. The second layer may be formed on a major surface of the first layer, the second layer having fifth and sixth edges for abutting a second surface of the substrate. The first and second edges may extend beyond the fifth and sixth edges by a first predetermined lateral distance. In addition, the first and second edges may form a curved corner, while the fifth and sixth edges may form a corresponding curved corner. | 08-04-2011 |
Greg Hardee, Del Mar, CA US
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20120309815 | COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY OF OLIGONUCLEOTIDES - The present invention relates to compositions and methods which enhance the delivery of nucleic acids and other nucleosidic moieties via topical routes of administration. The invention relates to the use of an aqueous solution to preferentially deliver nucleic acids preferentially to hair follicles. The invention relates to a method of inhibiting hair growth comprising administration of a nucleic acid preferentially to a hair follicle. | 12-06-2012 |
Gregory Hardee, Del Mar, CA US
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20120238937 | METHOD OF TREATING KELOIDS OR HYPERTROPHIC SCARS USING ANTISENSE COMPOUNDS TARGETING CONNECTIVE TISSUE GROWTH FACTOR (CTGF) - This invention provides methods of preventing formation of, or treating, fibrotic lesions, including skin scars such as keloids and hypertrophic scars which comprise administering to the subject by one or more injection a compound which comprises a modified oligonucleotide, such as a modified antisense oligonucleotide, siRNA, or oligodeoxyribonucleotide, which inhibits expression of protein involved in fibrosis. Dosing of the antisense using an intradermal threading technique is also described. | 09-20-2012 |
Gregory E. Hardee, Ranacho Santa Fe, CA US
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20090326045 | COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY OF OLIGONUCLEOTIDES - The present invention relates to compositions and methods which enhance the delivery of oligonucleotides and other nucleosidic moieties via topical routes of administration. Preferred compositions include liposomes or penetration enhancers for the delivery of such moieties to dermal and/or epidermal tissue in an animal for investigative, therapeutic or prophylactic purposes. | 12-31-2009 |
Gregory E. Hardee, Del Mar, CA US
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20110213014 | COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY OF OLIGONUCLEOTIDES - The present invention relates to compositions and methods which enhance the delivery of oligonucleotides and other nucleosidic moieties via topical routes of administration. Preferred compositions include liposomes or penetration enhancers for the delivery of such moieties to dermal and/or epidermal tissue in an animal for investigative, therapeutic or prophylactic purposes. | 09-01-2011 |
20110256217 | PULSATILE RELEASE COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL DRUG ABSORPTION - Delayed release oral pharmaceutical formulations and methods for enhanced intestinal drug absorption. The formulation comprises a first population of carrier particles comprising a drug and a penetration enhancer which are released at a first location in the intestine, and a second population of carrier particles comprising a penetration enhancer and a delayed release coating or matrix. This penetration enhancer is released at a second location in the intestine downstream from the first location and enhances absorption of the drug when it reaches the second location. | 10-20-2011 |
20130274309 | COMPOSITIONS AND METHODS FOR NON-PARENTERAL DELIVERY OF OLIGONUCLEOTIDES - The present invention relates to compositions and methods which enhance the local and systemic uptake and delivery of oligonucleotides and nucleic acids via non-parenteral routes of administration. Pharmaceutical compositions comprising oligonucleotides disclosed herein include, for systemic delivery, emulsion and microemulsion formulations for a variety of applications and oral dosage formulations. It has also surprisingly been discovered that oligonucleotides may be locally delivered to colonic sites by rectal enemas and suppositories in simple solutions, e.g., neat or in saline. Such pharmaceutical compositions of oligonucleotides may further include one or more penetration enhancers for the transport of oligonucleotides and other nucleic acids across mucosal membranes. The compositions and methods of the invention are utilized to effect the oral, buccal, rectal or vaginal administration of an antisense oligonucleotide to an animal in order to modulate the expression of a gene in the animal for investigative, therapeutic, palliative or prophylactic purposes | 10-17-2013 |
Gregroy Hardee, Del Mar, CA US
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20120322851 | ORAL DELIVERY OF THERAPEUTICALLY EFFECTIVE LNA OLIGONUCLEOTIDES - The invention provides for LNA oligomers, for the treatment of a metabolic or liver disorder, wherein the LNA oligomer is administered orally in a unit dose of less than 50 mgs/kg, wherein the LNA oligomer is administered in the presence of a penetration (permeation) enhancer. | 12-20-2012 |
H. Lenora Hardee, Fort Wayne, IN US
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20080264194 | INTEGRATED AUTOMATIC MANUAL TRANSMISSION LEVER-TYPE SHIFT SELECTOR - A bimodal shifter assembly provides a radically simplified mechanical arrangement for movement of the shifter in each of two modes along distinct shift paths. | 10-30-2008 |
Jim Hardee, Tulsa, OK US
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20110110803 | GAS/FLUID INHIBITOR TUBE SYSTEM - A pump assembly is disclosed. The pump has a suction opening. A motor is configured to drive the pump. The pump includes an inhibitor tube having an outlet configured to be in fluid communication with the suction opening. | 05-12-2011 |
Kenneth L. Hardee, Middlefield, OH US
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20090211918 | ELECTROCHEMICAL CELL AND METHOD FOR OPERATING THE SAME - The invention relates to an electrochemical cell comprising an arrangement of anode/cathode pairs, in which the accumulation of scales or similar fouling phenomena are prevented by alternatively operating either the anode or the cathode of one pair and the corresponding counterelectrode of the adjacent pair, the non-operated electrode of each pair being at open circuit. The electrolyte dissolves the scale deposits on the electrodes at open circuit, without resorting to harmful current reversal. | 08-27-2009 |
20100044219 | Smooth Surface Morphology Chlorate Anode Coating - The present invention relates to an electrocatalytic coating and an electrode having the coating thereon, wherein the coating is a mixed metal oxide coating, preferably ruthenium, titanium and tin or antimony oxides. The coating uses water as a solvent that provides for a smoother surface than alcohol based solvents. The electrocatalytic coating can be used especially as an anode component of an electrolysis cell and in particular a cell for the electrolysis of aqueous chlor-alkali solutions. | 02-25-2010 |
20110174628 | CATHODE MEMBER AND BIPOLAR PLATE FOR HYPOCHLORITE CELLS - A cathodic member for electrochemical cells used in hypochlorite production comprises a zirconium plate coated with a zirconium oxide layer, which is particularly suitable for minimising the decomposition of the hypochlorite product while ensuring a prolonged lifetime. The coated zirconium plate can be used as the cathodic plate in a monopolar cell, or can be welded to a titanium plate for use in a bipolar configuration. | 07-21-2011 |
20120318748 | ELECTROCHLORINATION METHOD FOR ABOVE-GROUND SWIMMING POOLS - The invention relate to the addition of mixture of non-halide salts to the water of above-ground swimming pools to allow sterilisation by in-situ electrochlorination with a modest sodium chloride content. A limitation of sodium chloride concentration in above-ground pools is necessary to prevent corrosion of the relevant steel supporting structure. The salt mixture additive contains sodium bisulphate and other salts of low toxicity. | 12-20-2012 |
Kim C. Hardee, Colorado Springs, CO US
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20090072879 | SHORT-CIRCUIT CHARGE-SHARING TECHNIQUE FOR INTEGRATED CIRCUIT DEVICES - A short-circuit charge-sharing technique which allows charge-sharing between two or more circuits with a simple shorting transistor controlled to achieve the desired operating voltage levels. The shorting transistor which can be either a P-channel Metal Oxide Semiconductor (PMOS) or an N-channel Metal Oxide Semiconductor (NMOS) device and can be controlled utilizing the same clock that enables the drive of the signals between which charge-sharing occurs. In operation, the desired operating voltage levels can be regulated by increasing and decreasing the pulse width of the control circuit output to the gate of the shorting transistor. | 03-19-2009 |
20090073786 | EARLY WRITE WITH DATA MASKING TECHNIQUE FOR INTEGRATED CIRCUIT DYNAMIC RANDOM ACCESS MEMORY (DRAM) DEVICES AND THOSE INCORPORATING EMBEDDED DRAM - An early write with data masking technique for dynamic random access memory (DRAM) devices and those devices incorporating embedded DRAM. The technique of the present invention allows for early writes to DRAM arrays with direct bit, byte or word data masking capability. | 03-19-2009 |
20090106488 | STATIC RANDOM ACCESS MEMORY (SRAM) COMPATIBLE, HIGH AVAILABILITY MEMORY ARRAY AND METHOD EMPLOYING SYNCHRONOUS DYNAMIC RANDOM ACCESS MEMORY (DRAM) IN CONJUNCTION WITH A DATA CACHE AND SEPARATE READ AND WRITE REGISTERS AND TAG BLOCKS - A high-speed, static random access memory (SRAM) compatible, high availability memory array and method employing synchronous dynamic random access memory (DRAM) in conjunction with a data cache and separate data read and write registers and tag blocks. The inclusion of separate data read and write registers allows the device to effectively operate at a cycle time limited only by the DRAM subarray cycle time. Further, the inclusion of two tag blocks allows one to be accessed with an externally supplied address and the other to be accessed with a write-back address, thus eliminating the requirement for a single tag to execute two read-modify write cycles in one DRAM cycle time. | 04-23-2009 |
20120008444 | DUAL BIT LINE PRECHARGE ARCHITECTURE AND METHOD FOR LOW POWER DYNAMIC RANDOM ACCESS MEMORY (DRAM) INTEGRATED CIRCUIT DEVICES AND DEVICES INCORPORATING EMBEDDED DRAM - A dual bit line precharge architecture and method for low power DRAM which provides the low operating voltage of a non-half supply voltage (VCC/2) precharge with the low memory array current consumption and low memory array noise spike of VCC/2 precharge techniques. The architecture and technique of the present invention provides both reference voltage (VSS) precharged sub arrays and VCC precharged sub arrays on the same DRAM memory either with or without the novel charge sharing or charge recycling circuitry between these two different sub arrays as disclosed herein. | 01-12-2012 |
20120008445 | DUAL BIT LINE PRECHARGE ARCHITECTURE AND METHOD FOR LOW POWER DYNAMIC RANDOM ACCESS MEMORY (DRAM) INTEGRATED CIRCUIT DEVICES AND DEVICES INCORPORATING EMBEDDED DRAM - A dual bit line precharge architecture and method for low power DRAM which provides the low operating voltage of a non-half supply voltage (VCC/2) precharge with the low memory array current consumption and low memory array noise spike of VCC/2 precharge techniques. The architecture and technique of the present invention provides both reference voltage (VSS) precharged sub arrays and VCC precharged sub arrays on the same DRAM memory either with or without the novel charge sharing or charge recycling circuitry between these two different sub arrays as disclosed herein. | 01-12-2012 |
Patrice L. Hardee, Beaufort, SC US
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20090313795 | Reclosable locking tape - A reclosable locking tape for releasably attaching a fabric add-on to a foundation includes: (a) a substantially planar tape base to which is affixed at least one male locking portion that is generally mushroom-shaped and includes a stem affixed to a cap; and (b) at least one female locking portion affixed to the tape base, the female locking portion including two same-sized hook members on opposite sides of a male portion-sized space in the female portion. Also included are a reclosable rib and groove tape assembly that includes: (a) a fabric add-on including at least one longitudinally extending rib or groove on a substantially planar and flexible portion backing; and (b) a separate foundation attachment portion including at least one rib or groove on a substantially planar portion backing, the rib or groove of the foundation attachment portion corresponding to the rib or groove of the add-on attachment portion, and a related method. | 12-24-2009 |