Patent application number | Description | Published |
20120065169 | OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS - Oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3′ and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects. | 03-15-2012 |
20120289457 | PEPTIDE OLIGONUCLEOTIDE CONJUGATES - Oligonucleotide analogues conjugated to carrier peptides are provided. The disclosed compounds are useful for the treatment of various diseases, for example diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects. | 11-15-2012 |
20140107013 | COMPOUND AND METHOD FOR TREATING MYOTONIC DYSTROPHY - Provided are 9-base morpholino antisense compounds targeted to polyCUG repeats in the 3′UTR region of dystrophia myotonica protein kinase (DMPK) mRNA, and related methods for treating myotonic dystrophy DM1. | 04-17-2014 |
20140303238 | OLIGONUCLEOTIDES FOR TREATING EXPANDED REPEAT DISEASES - The invention provides for a method for selectively reducing the expression of a mutant mRNA and/or protein having an expanded nucleotide repeat relative to a wild-type mRNA, comprising contacting a cell with an antisense oligonucleotide of sufficient length and complementarity to the expanded nucleotide repeat. More particularly it relates to selectively reducing the expression of mutant Huntington protein associated with Huntington's disease. The antisense oligonucleotide comprising either a nucleotide or a repeated three nucleotide sequence as defined in the claims. | 10-09-2014 |
20140330006 | FUNCTIONALLY-MODIFIED OLIGONUCLEOTIDES AND SUBUNITS THEREOF - Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3′ and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects. | 11-06-2014 |
20150073140 | OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS - Oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3′ and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects. | 03-12-2015 |
20150080340 | BORONIC ACID CONJUGATES OF OLIGONUCLEOTIDE ANALOGUES - Oligonucleotide analogues comprising boronic acid and/or boronic ester moieties are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects. | 03-19-2015 |
20150141321 | COMPOUND AND METHOD FOR TREATING MYOTONIC DYSTROPHY - Provided are 9-base morpholino antisense compounds targeted to polyCUG repeats in the 3′UTR region of dystrophia myotonica protein kinase (DMPK) mRNA, and related methods for treating myotonic dystrophy DM1. | 05-21-2015 |
Patent application number | Description | Published |
20090018959 | METHODS AND SYSTEMS FOR EXCHANGING AND/OR TRANSFERRING VARIOUS FORMS OF VALUE - Methods and systems for exchanging various forms of value, including coins, currency, credit, debit, and/or bank account funds, for prepaid cash cards, credit cards, phone cards, and the like. In one embodiment, a value exchange machine includes a coin input region, a coin sorting/counting apparatus, a card reader, and a communications facility configured to communicate with a remote computer network. In another embodiment, a value exchange system includes one or more of the value exchange machines connected to one or more remote computers via a communications link. A user wishing to purchase, for example, a prepaid cash card can visit one of the value exchange machines, select the desired transaction, and pay for the card with coins, currency, a credit card, a debit card, and/or bank account funds. After confirming payment, the value exchange machine dispenses the card to the user. | 01-15-2009 |
20100100481 | METHODS AND SYSTEMS FOR EXCHANGING AND/OR TRANSFERRING VARIOUS FORMS OF VALUE - Methods and systems for exchanging various forms of value, including coins, currency, credit, debit, and/or bank account funds, for prepaid cash cards, credit cards, phone cards, and the like. In one embodiment, a value exchange machine includes a coin input region, a coin sorting/counting apparatus, a card reader, and a communications facility configured to communicate with a remote computer network. In another embodiment, a value exchange system includes one or more of the value exchange machines connected to one or more remote computers via a communications link. A user wishing to purchase, for example, a prepaid cash card can visit one of the value exchange machines, select the desired transaction, and pay for the card with coins, currency, a credit card, a debit card, and/or bank account funds. After confirming payment, the value exchange machine dispenses the card to the user. | 04-22-2010 |
20100198726 | METHODS AND SYSTEMS FOR EXCHANGING/TRANSFERRING GIFT CARDS - Methods and systems for exchanging various forms of value, including coins, currency, credit, debit, and/or bank account funds, for prepaid cash cards, credit cards, phone cards, and the like. In one embodiment, a value exchange machine includes a coin input region, a coin sorting/counting apparatus, a card reader, and a communications facility configured to communicate with a remote computer network. In another embodiment, a value exchange system includes one or more of the value exchange machines connected to one or more remote computers via a communications link. A user wishing to purchase, for example, a prepaid cash card can visit one of the value exchange machines, select the desired transaction, and pay for the card with coins, currency, a credit card, a debit card, and/or bank account funds. After confirming payment, the value exchange machine dispenses the card to the user. | 08-05-2010 |
20110307378 | METHODS AND SYSTEMS FOR EXCHANGING/TRANSFERRING GIFT CARDS - Methods and systems for exchanging various forms of value, including coins, currency, credit, debit, and/or bank account funds, for prepaid cash cards, credit cards, phone cards, and the like. In one embodiment, a value exchange machine includes a coin input region, a coin sorting/counting apparatus, a card reader, and a communications facility configured to communicate with a remote computer network. In another embodiment, a value exchange system includes one or more of the value exchange machines connected to one or more remote computers via a communications link. A user wishing to purchase, for example, a prepaid cash card can visit one of the value exchange machines, select the desired transaction, and pay for the card with coins, currency, a credit card, a debit card, and/or bank account funds. After confirming payment, the value exchange machine dispenses the card to the user. | 12-15-2011 |
20130091055 | METHODS AND SYSTEMS FOR EXCHANGING AND/OR TRANSFERRING VARIOUS FORMS OF VALUE - Methods and systems for exchanging various forms of value, including coins, currency, credit, debit, and/or bank account funds, for prepaid cash cards, credit cards, phone cards, and the like. In one embodiment, a value exchange machine includes a coin input region, a coin sorting/counting apparatus, a card reader, and a communications facility configured to communicate with a remote computer network. In another embodiment, a value exchange system includes one or more of the value exchange machines connected to one or more remote computers via a communications link. A user wishing to purchase, for example, a prepaid cash card can visit one of the value exchange machines, select the desired transaction, and pay for the card with coins, currency, a credit card, a debit card, and/or bank account funds. After confirming payment, the value exchange machine dispenses the card to the user. | 04-11-2013 |
20140201012 | METHODS AND SYSTEMS FOR EXCHANGING AND/OR TRANSFERRING VARIOUS FORMS OF VALUE - Methods and systems for exchanging various forms of value, including coins, currency, credit, debit, and/or bank account funds, for prepaid cash cards, credit cards, phone cards, and the like. In one embodiment, a value exchange machine includes a coin input region, a coin sorting/counting apparatus, a card reader, and a communications facility configured to communicate with a remote computer network. In another embodiment, a value exchange system includes one or more of the value exchange machines connected to one or more remote computers via a communications link. A user wishing to purchase, for example, a prepaid cash card can visit one of the value exchange machines, select the desired transaction, and pay for the card with coins, currency, a credit card, a debit card, and/or bank account funds. After confirming payment, the value exchange machine dispenses the card to the user. | 07-17-2014 |
20140289111 | METHODS AND SYSTEMS FOR EXCHANGING AND/OR TRANSFERRING VARIOUS FORMS OF VALUE - Methods and systems for exchanging various forms of value, including coins, currency, credit, debit, and/or bank account funds, for prepaid cash cards, credit cards, phone cards, and the like. In one embodiment, a value exchange machine includes a coin input region, a coin sorting/counting apparatus, a card reader, and a communications facility configured to communicate with a remote computer network. In another embodiment, a value exchange system includes one or more of the value exchange machines connected to one or more remote computers via a communications link. A user wishing to purchase, for example, a prepaid cash card can visit one of the value exchange machines, select the desired transaction, and pay for the card with coins, currency, a credit card, a debit card, and/or bank account funds. After confirming payment, the value exchange machine dispenses the card to the user. | 09-25-2014 |
Patent application number | Description | Published |
20080235242 | Advanced Contact Management in Communications Networks - A system provided herein permits a communications network subscriber to establish a local contact database on at least one communications device. The local contact database can communicate with a global contact database to receive contact information updates for a group of subscribers stored within the local contact database. The contact information can include basic contact information, such as name, address, email address, and telephone number. The contact information can also include advanced contact information, such as registration and activity information for each communications device associated with the group of subscribers, location information, hotspot information, points of interest information, and social networking information. Methods are provided herein that permit subscribers to introduce each other and obtain contact information securely. Methods are also provided herein that permit subscribers to request further contact information after a communication session is terminated. | 09-25-2008 |
20090022285 | Dynamic Voicemail Receptionist System - A voicemail receptionist system includes a memory and a processor. The memory can store data relating to one or more users. An incoming communication can be handled by the voicemail receptionist system and provided with functionality based upon a user's preferences, for example. The data stored by the voicemail receptionist system can be updated at any time, or automatically updated upon updating of the data, or upon occurrence of a trigger event. Voicemail receptionist functionality can include standard voicemail system functionality as well as functionality relating to email, text messaging, MMS messaging, calendar features, schedule announcements, location data, as well as other features. | 01-22-2009 |
20090024633 | Systems and methods for remote deletion of contact information - An exemplary system for providing remote deletion of contact information includes a first device associated with a first user. The first device is configured to generate and send a delete request message to a second device. In some embodiments, the delete request message includes a request to delete contact information for the first user from the second device. The second device can be configured to receive the delete request message and delete the first user's contact information. A method for providing remote deletion of contact information includes a delete request message being generated at a first device, associated with a first user. The delete request message can include a request to delete contact information for the first user. The first device can send the delete request message to a second device. The delete request message can instruct the second device to delete the first user's contact information. | 01-22-2009 |
20090285129 | Systems and Methods for Delayed Message Delivery - A system for delayed message delivery can include an IP Multimedia Subsystem (IMS) network that is in communication with at least one of a first user equipment and a second user equipment, and a message application server. The message application server can be configured to receive a message sent from the first user equipment, store the message temporarily in accordance with a time parameter, and send the message to a gateway when the time parameter is satisfied. The gateway can be configured to receive a message formatted in accordance with a first protocol used by the IMS network and convert the message into a format in accordance with a second protocol used by a message center. The message center can be configured to receive the message formatted in accordance with the second protocol and forward the message to the second user equipment. Other systems for delayed message delivery and corresponding methods are disclosed. | 11-19-2009 |
20100287241 | Enhanced Messaging Feature - The present disclosure provides various systems and methods for providing enhanced messaging features. An exemplary method for providing a predictive response messaging feature includes receiving a message from a first device ( | 11-11-2010 |
20120066177 | Systems and Methods for Remote Deletion of Contact Information - An exemplary system for providing remote deletion of contact information includes a first device associated with a first user. The first device is configured to generate and send a delete request message to a second device. In some embodiments, the delete request message includes a request to delete contact information for the first user from the second device. The second device can be configured to receive the delete request message and delete the first user's contact information. A method for providing remote deletion of contact information includes a delete request message being generated at a first device, associated with a first user. The delete request message can include a request to delete contact information for the first user. The first device can send the delete request message to a second device. The delete request message can instruct the second device to delete the first user's contact information. | 03-15-2012 |
20150201074 | Dynamic Voicemail Receptionist System - A voicemail receptionist system includes a memory and a processor. The memory can store data relating to one or more users. An incoming communication can be handled by the voicemail receptionist system and provided with functionality based upon a user's preferences, for example. The data stored by the voicemail receptionist system can be updated at any time, or automatically updated upon updating of the data, or upon occurrence of a trigger event. Voicemail receptionist functionality can include standard voicemail system functionality as well as functionality relating to email, text messaging, MMS messaging, calendar features, schedule announcements, location data, as well as other features. | 07-16-2015 |
Patent application number | Description | Published |
20090148225 | Tube With Resilient Applicator For Dispensing Texture Materials - A system for applying texture material to a destination surface comprising a textured portion formed by a spray system and an untextured portion comprises a container and a sponge assembly. The container is flexible such that applying deliberate manual force to the container forces the texture material onto an applicator surface defined by the sponge assembly. The sponge member is resilient. When the container member is displaced along a dispensing axis towards and away from the destination surface with the applicator surface substantially parallel to the destination surface, at least a portion of the texture material on the applicator comes into contact with the untextured portion of the destination surface to transfer texture material from the applicator surface to the destination surface. At least a portion of an exposed portion of the particulate material stands out from and is visually perceptible on the untextured portion of the destination surface. The texture material forms a coat of new texture material that substantially matches an appearance of the textured portion of the destination surface formed by the spray system. | 06-11-2009 |
20100329772 | TUBE WITH RESILIENT APPLICATOR AND SCRAPER FOR DISPENSING TEXTURE MATERIALS - A method of patching a destination surface to substantially match a structure of an existing sprayed on visible texture pattern. A sponge member is displaced in a dabbing direction towards and away from the destination surface to transfer texture material to the destination surface. Individual particles of the texture material are supported by binder on the applicator surface such that at least a portion of the structure at least some of the individual particles supported on the applicator surface visibly extend from the destination surface. The portion of the structure of the individual particles supported by the binder that extends outwardly from the binder on the destination surface forms a visible structure on the destination surface. The visible structure substantially matches the structure of the existing sprayed on visible texture pattern. | 12-30-2010 |
20110081488 | Tube With Resilient Applicator for Dispensing Texture Materials - A method of applying texture material to a destination surface defining a pre-textured portion formed by a spray system and an untextured portion, comprising the following steps. A flexible container, texture, material, a sponge base, a resilient sponge are provided. The resilient sponge is adhered to the sponge base to form a sponge assembly. The texture material is arranged within the container chamber, and the sponge member is fixed relative to the container. Texture material is forced out of the container member and onto an applicator surface. At least a portion of the texture material on the applicator surface is transferred to the untextured portion of the destination surface by displacing the container member along the dispensing axis towards the destination surface with the applicator surface substantially parallel to the destination surface. The container member is then displaced away from the destination surface along the dispensing axis with the applicator surface substantially parallel to the destination surface such that an exposed portion of the particulate material on the untextured portion of the destination surface stands out from the destination surface and is visually perceptible. | 04-07-2011 |
20130011560 | TUBE WITH RESILIENT APPLICATOR AND SCRAPER FOR DISPENSING TEXTURE MATERIALS - A system for applying a coating to an untextured portion of a destination surface comprises a tube member defining a container opening, texture material within the tube member, a sponge member defining an applicator surface and a sponge opening. The texture material comprises a binder and visually perceivable discrete particles. The sponge member is secured to the tube member such that the texture material can flow out of the tube member through the sponge opening. The texture material is displaced out of the tube member and onto the applicator surface. The applicator surface of the sponge member is displaced substantially along a dispensing axis perpendicular to the applicator surface towards and away from the destination surface with the applicator surface substantially parallel to the destination surface to transfer the texture material to the destination surface. | 01-10-2013 |
20130022747 | Tube With Resilient Applicator for Dispensing Texture Material - The present invention may be embodied as an apparatus for applying texture material to a destination surface defining a pre-textured portion formed by a spray system and an untextured portion, where the pre-textured portion comprises visually perceptible particles. The apparatus comprises a flexible container defining a container chamber, texture material arranged within the container chamber, a sponge base, and a sponge member. The application of deliberate manual force to the container forces the texture material in the container chamber out of the container member. The sponge member is angled with respect to the dispensing axis such that a visually perceptible exposed portion of the particulate material transferred to the untextured portion of the destination surface is allowed to project from the destination surface after the texture material is deposited on the destination surface. | 01-24-2013 |
20130026252 | Systems and Methods for Dispensing Texture Material Using Dual Flow Adjustment - An aerosol dispensing system for dispensing stored material in a spray comprises a container, a conduit, a valve system, a first adjustment system, and a second adjustment system. The container defines a chamber containing the stored material and pressurized material. The conduit defines a conduit passageway having a conduit inlet and a conduit outlet. The conduit inlet is arranged within the chamber, and the conduit outlet is arranged outside of the chamber. The valve system is arranged to allow and prevent flow of stored material along the conduit passageway. The first adjustment system is arranged to control flow of stored material along the conduit passageway. The first adjustment system is arranged between the conduit inlet and the conduit outlet. The second adjustment system is arranged to control flow of stored material along the conduit passageway. The second adjustment system is arranged between the first adjustment system and the conduit outlet. | 01-31-2013 |
20130026253 | Systems and Methods for Dispensing Texture Material Using Dual Flow Adjustment - An aerosol dispenser for dispensing stored material in a spray comprises a container, a conduit, and first and second adjustment systems. The container defines a chamber containing the stored material and pressurized material. The conduit defines a conduit passageway having a conduit inlet and a conduit outlet. The conduit inlet is arranged within the chamber and the conduit outlet is arranged outside of the chamber. The first adjustment system is arranged to vary a flow of stored material along the conduit passageway and is arranged between the conduit inlet and the conduit outlet. The second adjustment system arranged to vary a flow of stored material along the conduit passageway and is arranged between the first adjustment system and the conduit outlet. | 01-31-2013 |
20130287951 | Spray Texture Material Compositions and Dispensing Systems and Methods - A system for coating a target surface employs a bottle for containing the texture material and a spray pump assembly. A resilient member is supported by a pump housing to define an outlet opening. A collar member is supported by the pump housing. The resilient member is normally in an undeformed configuration in which the outlet opening defines a first cross-sectional area. Moving the collar member relative to the pump housing causes the collar member to act on the resilient member to deform the resilient member from the undeformed configuration to a deformed configuration in which the outlet opening defines a second cross-sectional area, where the second cross-sectional area is greater than the first cross-sectional area. | 10-31-2013 |
20140072714 | PIGMENTED SPRAY TEXTURE MATERIAL COMPOSITIONS, SYSTEMS, AND METHODS - A method of applying a coating material to a target surface defined by a wall comprises providing a pigmented texture material, combining the texture material with a propellant in a main chamber, operating a valve assembly to allow the propellant material to force the texture material out of the main chamber in discrete droplets, and arranging the container assembly such that the discrete droplets are deposited on the target surface. The binder material, filler material, and pigment material are combined such that the discrete droplets define a physical structure that is visibly distinct from the target surface, where the binder material is provided in an amount sufficient to maintain the physical structure of and to bind the discrete droplets to the target surface. The discrete droplets also define a texture color associated with a color of the pigment material. When dry, the discrete droplets are sufficiently durable to function as part of a final wall surface. | 03-13-2014 |
20140162023 | Tube with Resilient Applicator and Scraper for Dispensing Texture Materials - A system for applying a coating to an untextured portion of a destination surface comprises a tube member defining a container opening, texture material within the tube member, a sponge member defining an applicator surface and a sponge opening. The texture material comprises a binder and visually perceivable discrete particles. The sponge member is secured to the tube member such that the texture material can flow out of the tube member through the sponge opening. The texture material is displaced out of the tube member and onto the applicator surface. The applicator surface of the sponge member is displaced substantially along a dispensing axis perpendicular to the applicator surface towards and away from the destination surface with the applicator surface substantially parallel to the destination surface to transfer the texture material to newly textured portion of the destination surface. | 06-12-2014 |
20140263417 | Adapter Systems and Methods for Aerosol Dispensing Systems - A dispenser for aerosol material includes an aerosol assembly, an adapter assembly comprising a fixed member and a removable member, and an actuator assembly. When the dispenser is in a first configuration, the fixed member is attached to the rim structure, and the removable member is detachably attached to the fixed member. When the dispenser is in a second configuration, the fixed member is attached to the rim structure, and the actuator assembly is detachably attached to the fixed member. The removable member substantially covers a valve structure of the aerosol assembly when the dispenser is in the first configuration. The actuator assembly engages the valve assembly to allow product to be dispensed from the aerosol assembly when the dispenser is in the second configuration. | 09-18-2014 |
20140272124 | Coating Systems and Methods for Countertops - A method of forming a restored countertop surface on an existing countertop surface comprises the step of applying discrete portions of a secondary material onto a base coat formed of uncured base material. The base material and the secondary material are formulated such that the secondary material does not mix with the base material and a visual appearance of the secondary material is different from that of the base material. At least one of the base material and the secondary material harden to form the restored countertop surface. | 09-18-2014 |
20140272140 | Acoustic Ceiling Popcorn Texture Materials, Systems, and Methods - An actuator for forming a texture layer on a target surface has a housing, a trigger, and an adapter. The housing supports the trigger for pivoting movement between first and second trigger positions. The housing supports the adapter member for sliding movement between first and second adapter positions. The trigger engages the adapter to displace the adapter from the first adapter position to the second adapter position as the trigger moves from the first trigger position to the second trigger position. The adapter engages a valve assembly such that the valve assembly is in closed and open configurations when the adapter is in the first and second adapter positions. | 09-18-2014 |
20150050425 | Ceiling Texture Materials, Systems, and Methods - An aerosol dispensing system has a container assembly, an actuator assembly, and a trigger member. The container assembly has a valve assembly. The actuator assembly has an actuator housing defining a rail portion, a trigger member pivotably attached to the actuator housing, and an outlet assembly defining an outlet opening. The outlet assembly is slidably supported relative to the actuator housing by the rail portion. The trigger member engages the outlet assembly such that application of deliberate manual force on the trigger member causes pivoting movement of the trigger member relative to the actuator housing and such that pivoting movement of the trigger member relative to the actuator housing causes linear movement of the outlet assembly relative to the actuator housing. The outlet assembly engages the valve assembly such that linear movement of the outlet assembly alters the valve assembly from a closed configuration to a fully open configuration. | 02-19-2015 |
Patent application number | Description | Published |
20120330787 | PAYMENT SELECTION AND AUTHORIZATION - When making a payment with an electronic payment type, a user may provide additional verification of ownership through communications with the user's mobile computing device. For example, the user may swipe her bank card at a retailer's store. The retailer may authorize the bank card through an issuing party (“host”). The host may transmit a request to the user via a mobile application running on the mobile computing device, which may request the user to approve or decline the purchase request. In various embodiments, the host's request may require the user to enter personal and/or authorization information (e.g., a PIN, password, biometrics, etc.) via the mobile application to approve the request. In some aspects, the host may allow the user to split or allocate a payment amount across one or more electronic payment types available to the user from the host via the mobile application during the authorization process. | 12-27-2012 |
20120330788 | PAYMENT SELECTION AND AUTHORIZATION BY A MOBILE DEVICE - When making a payment with an electronic payment type, a user may provide additional verification of ownership through communications with the user's mobile computing device. For example, the user may swipe her bank card at a retailer's store. The retailer may authorize the bank card through an issuing party (“host”). The host may transmit a request to the user via a mobile application running on the mobile computing device, which may request the user to approve or decline the purchase request. In various embodiments, the host's request may require the user to enter personal and/or authorization information (e.g., a PIN, password, biometrics, etc.) via the mobile application to approve the request. In some aspects, the host may allow the user to split or allocate a payment amount across one or more electronic payment types available to the user from the host via the mobile application during the authorization process. | 12-27-2012 |
20130151419 | Merchant Verification of In-person Electronic Transactions - Validation data, such as an image selected by a merchant, is rendered on a mobile device of a customer to provide the merchant confirmation that payment for an item submitted through the mobile device of the customer was in fact received by the merchant. The merchant may establish an account on a network-accessible computing device (e.g., in the “cloud”) that includes the validation data. The customer authorizes payment to the merchant from the mobile device using the network connectivity of the mobile device. When the payment is received by the merchant, the network-accessible computing device sends the validation data to the customer's mobile device. The merchant may be confident that he or she has in fact received an electronic payment from the customer when the validation data is presented on the mobile device. Techniques to prevent reuse and copying of the validation data are also discussed. | 06-13-2013 |
20140143162 | SYSTEM AND METHOD FOR GATHERING DATA FOR DETECTING FRAUDULENT TRANSACTIONS - A system and method for gathering data for detecting fraudulent transactions includes, in one embodiment, a web page that contains a fraud data gathering script and causes a client device to download a fraud detection applet. The fraud data gathering script causes the client device to collect information from the client device that is usable to identify the client device. The fraud detection applet causes the client device to connect to an identification echo service server to obtain the actual IP address of the client device. The fraud detection data, including the identifying information and the actual IP address, are then sent to a web server and/or a fraud data gathering server for further processing and to determine whether a transaction with the client device is likely to be fraudulent. | 05-22-2014 |
Patent application number | Description | Published |
20130064807 | USE OF THROMBIN MUTANTS TO INHIBIT THE ANTICOAGULATION EFFECT OF THROMBIN INHIBITORS - The present disclosure provides methods for inhibiting the anticoagulation effect of a thrombin inhibitor in a patient in need thereof comprising administration of a therapeutically effective amount of a variant prothrombin or thrombin that is capable of binding the thrombin inhibitor and that has reduced procoagulant activity. Variant prothrombins or thrombins of use in the methods of the present disclosure include thrombin mutants W215A, W215A/E217A, or variants thereof in which the amino acids at positions 215 and/or 217 are alanine. Methods are also provided in which the thrombin mutants are administered with an additional active agent. In one embodiment, the methods are useful in the treatment of patients in which a direct thrombin inhibitor has been administered. The present disclosure further provides a method for quantifying the concentration of an anticoagulant in the plasma or whole blood of a patient using a variant prothrombin or thrombin titration assay. | 03-14-2013 |
20130171144 | ANTI-FACTOR XI MONOCLONAL ANTIBODIES AND METHODS OF USE THEREOF - The present invention relates to compositions and methods for inhibiting thrombosis without compromising hemostasis. Compositions include anti-factor XI monoclonal antibodies (aXIMabs) capable of binding to an epitope on the heavy chain of human FXI, particularly the A3 domain of the heavy chain of human FXI. Compositions also include epitope-binding fragments, variants, and derivatives of the monoclonal antibodies, cell lines producing these antibody compositions, and isolated nucleic acid molecules encoding the amino acid sequences of the antibodies. The invention further includes pharmaceutical compositions comprising the anti-factor XI monoclonal antibodies of the invention, or epitope-binding fragments, variants, or derivatives thereof, in a pharmaceutically acceptable carrier. Methods of the invention comprise administering the compositions described above to a subject in need thereof for the purpose of inhibiting thrombosis, reducing a required dose of an antithrombotic agent in the treatment of thrombosis, treating metastatic cancer, or treating an acute inflammatory reaction. | 07-04-2013 |
20140322219 | ANTI-FACTOR XI MONOCLONAL ANTIBODIES AND METHODS OF USE THEREOF - The present invention relates to compositions and methods for inhibiting thrombosis without compromising hemostasis. Compositions include anti-factor XI monoclonal antibodies (aXIMabs) capable of binding to an epitope on the heavy chain of human FXI, particularly the A3 domain of the heavy chain of human FXI. Compositions also include epitope-binding fragments, variants, and derivatives of the monoclonal antibodies, cell lines producing these antibody compositions, and isolated nucleic acid molecules encoding the amino acid sequences of the antibodies. The invention further includes pharmaceutical compositions comprising the anti-factor XI monoclonal antibodies of the invention, or epitope-binding fragments, variants, or derivatives thereof, in a pharmaceutically acceptable carrier. Methods of the invention comprise administering the compositions described above to a subject in need thereof for the purpose of inhibiting thrombosis, reducing a required dose of an antithrombotic agent in the treatment of thrombosis, treating metastatic cancer, or treating an acute inflammatory reaction. | 10-30-2014 |
20150322163 | ANTI-FACTOR XI MONOCLONAL ANTIBODIES AND METHODS OF USE THEREOF - Compositions and methods for inhibiting thrombosis without compromising hemostasis are described. Compositions include anti-factor XI monoclonal antibodies (aXIMabs) capable of binding to an epitope on the heavy chain of human FXI, particularly the A3 domain of the heavy chain of human FXI. Compositions also include epitope-binding fragments, variants, and derivatives of the monoclonal antibodies, cell lines producing these antibody compositions, and isolated nucleic acid molecules encoding the amino acid sequences of the antibodies. The disclosure further includes pharmaceutical compositions comprising the disclosed anti-factor XI monoclonal antibodies, or epitope-binding fragments, variants, or derivatives thereof, in a pharmaceutically acceptable carrier. Methods of the disclosure include administering the compositions described above to a subject in need thereof for the purpose of inhibiting thrombosis, reducing a required dose of an antithrombotic agent in the treatment of thrombosis, treating metastatic cancer, or treating an acute inflammatory reaction. | 11-12-2015 |
Patent application number | Description | Published |
20090204530 | BAR CODED MONETARY TRANSACTION SYSTEM AND METHOD - An improved financial transaction device comprising bar-coded information incorporating one of a plurality of algorithmic signatures, the signature being configured to permit at least one party involved in a financial transaction to store pertinent data in a multi-organizational payment tracking database, wherein the signature comprises a payment tracking identifier capable of uniquely referencing a single financial transaction and some of the pertinent data. The transaction may correspond to a format signature which may be in the form of a unique pictographic image representing the arrangement of data on a financial device for comparison against a library or database of signatures for purposes of device recognition. | 08-13-2009 |
20090259612 | MESSAGE CONDUIT SYSTEMS WITH ALGORITHMIC DATA STREAM CONTROL AND METHODS FOR PROCESSING THEREOF - A method for processing messages is provided where at least one algorithmic conduit is defined, and at least one conduit rule for controlling at least one algorithmic conduit is defined. An algorithmic conduit is a persistent connection, controlled by explicit, independent, dynamic rules, and capable of processing messages among data communicators such as devices, systems, or programs. Messages can be monitored, filtered, transformed, correlated, or processed in other ways without modifying the data communicators. A message conduit hub system allows creation and management of algorithmic conduits to serve as active, virtualized links carrying rules-based data streams among configurable endpoints. These “smart” connections are managed using parameters, logic, and other control interfaces for tailoring behavior to a particular application, site, or user. A message conduit hub system may be implemented as a stand-alone device, as part of a larger system, or as an “encapsulation layer” for an existing application. | 10-15-2009 |
20120136777 | BAR CODED MONETARY TRANSACTION SYSTEM AND METHOD - An improved financial transaction device comprising bar-coded information incorporating one of a plurality of algorithmic signatures, the signature being configured to permit at least one party involved in a financial transaction to store pertinent data in a multi-organizational payment tracking database, wherein the signature comprises a payment tracking identifier capable of uniquely referencing a single financial transaction and some of the pertinent data. The transaction may correspond to a format signature which may be in the form of a unique pictographic image representing the arrangement of data on a financial device for comparison against a library or database of signatures for purposes of device recognition. | 05-31-2012 |
20130046722 | MESSAGE CONDUIT SYSTEMS WITH ALGORITHMIC DATA STREAM CONTROL AND METHODS FOR PROCESSING THEREOF - A method for processing messages is provided where at least one algorithmic conduit is defined, and at least one conduit rule for controlling at least one algorithmic conduit is defined. An algorithmic conduit is a persistent connection, controlled by explicit, independent, dynamic rules, and capable of processing messages among data communicators such as devices, systems, or programs. Messages can be monitored, filtered, transformed, correlated, or processed in other ways without modifying the data communicators. A message conduit hub system allows creation and management of algorithmic conduits to serve as active, virtualized links carrying rules-based data streams among configurable endpoints. These “smart” connections are managed using parameters, logic, and other control interfaces for tailoring behavior to a particular application, site, or user. A message conduit hub system may be implemented as a stand-alone device, as part of a larger system, or as an “encapsulation layer” for an existing application. | 02-21-2013 |
20130117175 | BAR CODED MONETARY TRANSACTION SYSTEM AND METHOD - An improved financial transaction device comprising bar-coded information incorporating one of a plurality of algorithmic signatures, the signature being configured to permit at least one party involved in a financial transaction to store pertinent data in a multi-organizational payment tracking database, wherein the signature comprises a payment tracking identifier capable of uniquely referencing a single financial transaction and some of the pertinent data. The transaction may correspond to a format signature which may be in the form of a unique pictographic image representing the arrangement of data on a financial device for comparison against a library or database of signatures for purposes of device recognition. | 05-09-2013 |
20150287005 | BAR CODED MONETARY TRANSACTION SYSTEM AND METHOD - A method of administrating the life cycle of a financial transaction between a biller, a customer, and a plurality of third party processors, involving the recording, in a single multi-organizational payment tracking database, of a billing obligation as an element of a processing flow that reflects the financial transaction life cycle corresponding to the billing obligation, where the multi-organizational payment tracking database is configured to permit access by any one of the biller, customer, and plurality of third party processors to permit each participant to record, update and/or manage elements within the processing flow. | 10-08-2015 |