Patent application number | Description | Published |
20120016493 | Passive ankle-foot prosthesis and orthosis capable of automatic adaptation to sloped walking surfaces and method of use - The present invention relates to an improved system for use in rehabilitation and/or physical therapy for the treatment of injury or disease to the lower limbs or extremities. The system can enable an amputee to proceed over any inclined or declined surface without overbalancing. The system is mechanically passive in that it does not utilize motors, force generating devices, batteries, or powered sources that may add undesirable weight or mass and that may require recharging. In particular the system is self-adapting to adjust the torque moment depending upon the motion, the extent of inclination, and the surface topography. An additional advantage of the improvement is that the system can be light and may also be simple to manufacture. | 01-19-2012 |
20120116540 | Prosthetic foot and method of making - A prosthetic foot is made by machining or molding a prosthetic foot profile to have a plurality of slots in and along the length of the forefoot region of the foot shape to achieve the appropriate roll-over shape during walking, and slotting the heel region of the machined foot shape to provide shock absorption in early stance phase of walking. | 05-10-2012 |
20130006386 | Further improvements to ankle-foot prosthesis and orthosis capable of automatic adaptation to sloped walking surfaces and methods of use - The present invention relates to an improved system for use in rehabilitation and/or physical therapy for the treatment of injury or disease to the lower limbs or extremities. The system can enable an amputee to proceed over any inclined or declined surface without overbalancing. The system is mechanically passive in that it does not utilize motors, force generating devices, batteries, or powered sources that may add undesirable weight or mass and that may require recharging. In particular the system is self-adapting to adjust the torque moment depending upon the motion, the extent of inclination, and the surface topography. An additional advantage of the improvement is that the system can be light and may also be simple to manufacture. | 01-03-2013 |
20130096694 | VACUUM PUMP SYSTEMS FOR PROSTHETIC LIMBS AND METHODS OF USING THE SAME - Pump systems for use in suspension of a prosthetic device from a residual limb and methods of suspending a prosthetic device from a residual limb are disclosed. The pump systems include a mechanically activated pump having a first compression member coupled to a second compression member, a compressible bladder disposed between the first and second compression members, and coupling elements that engage and couple together the first and second compression members. The mechanically activated pump may be connected with an electrically activated pump within a fluid circuit of a hybrid pump system to provide vacuum engagement between a prosthetic device and a residual limb. | 04-18-2013 |
20140074255 | ARTIFICIAL ANKLE, ARTIFICIAL FOOT AND ARTIFICIAL LEG - The present invention relates in the field of orthopedics to an artificial ankle which imitates the natural human gait in a proper way, thereby enabling its user to walk not only in a plane environment but also uphill and downhill without any unpleasant effects. The present invention further relates to an artificial foot and an artificial leg containing said artificial ankle. | 03-13-2014 |
20140087920 | Foldable Parallel Bar Apparatus - A foldable parallel bar apparatus includes generally U-shaped first and second end frames and a set of handrails connected to and extending between the first and second end frames, wherein the handrails are foldable so as to move the first and second end frames closer to one another thereby compacting the apparatus. When multiple modules of the end frames are connected, they provide an uninterrupted path between the handrails. An alternative embodiment provides base platforms that are foldable relative to each other and handrails that are vertically and horizontally adjustable. | 03-27-2014 |
20140088730 | Ankle-Foot Prosthesis for Automatic Adaptation to Sloped Walking Surfaces - An ankle-foot prosthesis includes a foot plate, an ankle frame attached to the foot plate, a yoke pivotally connected to the ankle frame and including a member for attaching to a leg, a damper having a first end connected to the yoke and a second end connected to the ankle frame, and a control mechanism for switching the damper between low and high settings. | 03-27-2014 |
20150265435 | VACUUM PUMP SYSTEMS FOR PROSTHETIC LIMBS AND METHODS OF USING THE SAME - Pump systems for use in suspension of a prosthetic device from a residual limb and methods of suspending a prosthetic device from a residual limb are disclosed. The pump systems include a mechanically activated pump having a first compression member coupled to a second compression member, a compressible bladder disposed between the first and second compression members, and coupling elements that engage and couple together the first and second compression members. The mechanically activated pump may be connected with an electrically activated pump within a fluid circuit of a hybrid pump system to provide vacuum engagement between a prosthetic device and a residual limb. | 09-24-2015 |
20150265436 | VACUUM PUMP SYSTEMS FOR PROSTHETIC LIMBS AND METHODS OF USING THE SAME - Pump systems for use in suspension of a prosthetic device from a residual limb and methods of suspending a prosthetic device from a residual limb are disclosed. The pump systems include a mechanically activated pump having a first compression member coupled to a second compression member, a compressible bladder disposed between the first and second compression members, and coupling elements that engage and couple together the first and second compression members. The mechanically activated pump may be connected with an electrically activated pump within a fluid circuit of a hybrid pump system to provide vacuum engagement between a prosthetic device and a residual limb. | 09-24-2015 |
Patent application number | Description | Published |
20120284526 | PERSONAL IDENTIFICATION NUMBER SECURITY ENHANCEMENT - A system for enhancing security of a personal identification number is configned for performing a method that includes receiving, from a first entity having an input permission, a first data structure into a HSM, wherein the first data structure maps a first many-to-one mapping between a first and a second PIN numeral system. The method also includes determining whether the content of the first data structure is valid, storing the first data structure in the HSM if the first data structure is valid and marking the stored first data structure as inactive. The method further includes activating the first data structure if a second data structure is input into the HSM by a second entity having an activation permission, wherein the first entity is different from the second entity, the first data structure is identical to the second data structure. The method additionally includes converting from the first to the second PIN numeral system responsive to the activated first data structure. | 11-08-2012 |
20130073863 | PERSONAL IDENTIFICATION NUMBER SECURITY ENHANCEMENT - A method that includes receiving, from a first entity having an input permission, a first data structure into a HSM, wherein the first data structure maps a first many-to-one mapping between a first and a second PIN numeral system. The method also includes determining whether the content of the first data structure is valid, storing the first data structure in the HSM if the first data structure is valid and marking the stored first data structure as inactive. The method further includes activating the first data structure if a second data structure is input into the HSM by a second entity having an activation permission, wherein the first entity is different from the second entity, the first data structure is identical to the second data structure. The method additionally includes converting from the first to the second PIN numeral system responsive to the activated first data structure. | 03-21-2013 |
Patent application number | Description | Published |
20110083432 | Internal combustion engine and supercharger - A diesel or diesel-like internal combustion engine drivably connected to a variable internal compression ratio supercharger that supplies varying amounts of air to the engine responsive to the load requirements of the engine. The supercharger has a pair of rotors concurrently driven by the engine to move air to the engine. A slide assembly associated with screw rotors is movable with a controller relative to the rotors to bypass air to atmosphere and regulate the amount of air and pressure of the air compressed by the screw rotors to the engine to increase the engine's efficiency. | 04-14-2011 |
20110083647 | Internal combustion engine and supercharger - An internal combustion engine drivably connected to a variable displacement and variable internal compression ratio supercharger that supplies varying amounts of air to the engine air intake manifold that can range selectively from below through above atmospheric pressures responsive to the power requirements of the engine. The supercharger has a pair of rotors concurrently driven by the engine to move air to the engine. A slide assembly associated with screw rotors is movable with a controller relative to the rotors to bypass air to atmosphere and regulate the amount of air and pressure of the air above atmospheric pressure compressed by the screw rotors to the engine to increase the engine's efficiency. When operating at part-load unboosted, a throttle valve is operable to control the air mass flowing to the air intake manifold below atmospheric pressure to control the power of the engine. | 04-14-2011 |
20110204654 | Engine and supercharger - An internal combustion engine is coupled to a supercharger operable to supply varying amounts of air to the engine responsive to the load on the engine. The supercharger has a pair of screw rotors driven by the engine to move air to the engine and a control apparatus for varying the mass and pressure of air supplied to the engine. | 08-25-2011 |
20120041664 | Method for powering an apparatus - An internal combustion engine is coupled to a supercharger operable to supply varying amounts of air to the engine responsive to the load on the engine. The supercharger has a pair of screw rotors driven by the engine to move air to the engine and a control apparatus for varying the mass and pressure of air supplied to the engine. | 02-16-2012 |
20130261518 | BODY PULSATING APPARATUS AND METHOD - A device and method coupled to a therapy garment to apply pressure and repetitive compression forces to a body of a person has a positive air pulse generator and a user programmable time, frequency and pressure controller operable to regulate the duration of operation, frequency of the air pulses and a selected air pressure applied to the body of a person. The air pulse generator has rigid displacers that are angularly moved with crank power transmissions to draw air into the air pulse generator and discharge air pressure pulses to the therapy garment. | 10-03-2013 |
Patent application number | Description | Published |
20110158745 | VIBRATORY SYSTEM FOR A COMPACTOR - A vibratory system for a compactor is provided. The vibratory system has a first eccentric, a second eccentric, and a drive shaft. The second eccentric is rotatably and coaxially positioned with respect to the first eccentric. The drive shaft is rotatably coupled to the second eccentric and rotatably coupled to the first eccentric through a helical spline. | 06-30-2011 |
20130000429 | System and Method to Prevent Premature Wear on Key Shaft - A system and method for lubricating a key shaft in a compaction machine is disclosed. The compaction machine may include a spline oil cavity and a key shaft in fluid communication with the spline oil cavity. The key shaft may include an axial splined portion and a helical splined portion on an outer surface thereof, a longitudinal lubricating passage extending through a substantial length of the key shaft and a plurality of additional lubricating passages intersecting the longitudinal lubricating passage. The system and method may additionally include lubricating the axial splined portion and the helical splined portion of the key shaft with the lubricating oil drawn from the spline oil cavity. | 01-03-2013 |
20140133909 | ECCENTRIC WEIGHT SHAFT FOR VIBRATORY COMPACTOR - A vibratory compactor includes a roller and an eccentric shaft. The roller is rotatably mounted on a main frame and may include a first vertical support and a second vertical support. The eccentric shaft is rotatably connected between the first vertical support and the second vertical support in the roller. The eccentric shaft includes a first end, a second end, a first eccentric weight, a second eccentric weight, and a center portion, casted as a single piece. The first eccentric weight is proximal to the first end and the second eccentric weight is proximal to the second end. The center portion may be disposed between the first eccentric weight and the second eccentric weight. The center portion may include at least one cavity on a surface of the center portion. The at least one cavity is elongated between the first eccentric weight and the second eccentric weight. | 05-15-2014 |
Patent application number | Description | Published |
20080267599 | Heat exchanger for high flow rate infusion - A heat exchanger has a laminar fluid flow path receivable between the heating plates of a high flow rate infusion unit to which heat is conducted by contact with the heating plates. A bubble trap and a valve are integrated with the heat exchanger. The bubble trap collects air from the infusate exiting the laminar flow path, and includes an air vent in contact with the infusate that vents the air from the bubble trap. The valve shuts off the flow of infusate if air is detected in the bubble trap. | 10-30-2008 |
20080269663 | High flow rate infusion unit and heat exchanger - A high flow rate infusion unit includes a heating unit with opposing, electrically-operated heating plates that contact a heat exchanger to heat infusate flowing therethrough. Pressure infusers on the infusion unit are operable to provide infusate at a high flow rate. A flat, elongate heat exchanger has a laminar fluid flow path receivable between the heating plates to which heat is conducted by contact with the heating plates. A bubble trap and a valve are disposed within the heat exchanger. The bubble trap collects bubbles and vents air from infusate exiting the fluid flow path, and the valve shuts off the flow of infusate if the volume of air in the bubble trap exceeds a predefined limit. | 10-30-2008 |
20080269676 | High flow rate infusion with extraction assist - An infusion unit includes a heating unit with opposed heating plates. A heat exchanger has a fluid flow path receivable between the heating plates to which heat is conducted by contact with the heating plates. Infusate flowing under pressure through the fluid flow path is heated by conduction from the heating plates through the fluid container. When the flow of infusate is stopped or interrupted, infusate trapped in the heat exchanger is displaced to a reservoir in the heat exchanger. Displacement of the trapped infusate reduces friction between the fluid container and the heating plates, which assists in extraction of the heat exchanger from the heating unit. | 10-30-2008 |
20080269679 | Bubble trap for high flow rate infusion - A bubble trap for separating and collecting air and bubbles from a high flow rate stream of infusate includes multiple flow chambers to collect air, a sensor support mounted to one of the chambers, an air vent disposed in one of the chambers, and a valve in fluid communication with the chambers to control the flow of infusate therethrough. | 10-30-2008 |
20100185149 | Heat exchanger for high flow rate infusion - A heat exchanger has a laminar fluid flow path receivable between the heating plates of a high flow rate infusion unit to which heat is conducted by contact with the heating plates. A bubble trap and a valve are integrated with the heat exchanger. The bubble trap collects air from the infusate exiting the laminar flow path, and includes an air vent in contact with the infusate that vents the air from the bubble trap. The valve shuts off the flow of infusate if air is detected in the bubble trap. | 07-22-2010 |
20100222737 | High flow rate infusion unit and heat exchanger - A high flow rate infusion unit includes a heating unit with opposing, electrically-operated heating plates that contact a heat exchanger to heat infusate flowing therethrough. Pressure infusers on the infusion unit are operable to provide infusate at a high flow rate. A flat, elongate heat exchanger has a laminar fluid flow path receivable between the heating plates to which heat is conducted by contact with the heating plates. A bubble trap and a valve are disposed within the heat exchanger. The bubble trap collects bubbles and vents air from infusate exiting the fluid flow path, and the valve shuts off the flow of infusate if the volume of air in the bubble trap exceeds a predefined limit. | 09-02-2010 |
20100300293 | Bubble trap for high flow rate infusion - A bubble trap for separating and collecting air and bubbles from a high flow rate stream of infusate includes multiple flow chambers to collect air, a sensor support mounted to one of the chambers, an air vent disposed in one of the chambers, and a valve in fluid communication with the chambers to control the flow of infusate therethrough. | 12-02-2010 |
20110249699 | Zero-heat-flux, deep tissue temperature measurement devices with thermal sensor calibration - A zero-heat-flux DTT measurement device is constituted of a flexible substrate supporting an electrical circuit including a heater trace defining a heater, thermal sensors, and a thermal sensor calibration circuit. | 10-13-2011 |
20110249701 | Constructions for zero-heat-flux, deep tissue temprature measurement devices - The invention pertains to flexible devices used for zero-heat-flux, deep tissue temperature measurement, especially to disposable temperature measurement devices. Such a device is constituted of a flexible substrate. An electrical circuit is disposed on a side of the substrate. The electrical circuit includes first and second thermal sensors disposed, respectively, on first and second substrate layers. A heater trace is disposed on the first substrate layer with the first thermal sensor. The first and second substrate layers are separated by a flexible layer of insulation disposed between the first and second substrate layers. The heater trace defines a heater with a central portion that operates with a first power density and a peripheral portion around the central portion that operates with a second power density greater than the first power density. | 10-13-2011 |
20120289855 | Zero-heat-flux, deep tissue temperature measurement system - A zero-heat-flux, deep tissue temperature measurement system measures internal body temperature by way of a probe having a heater and thermal sensors arranged in a zero-heat-flux construction. The measurement system includes control mechanization that determines heater and skin temperatures based upon data obtained from the probe and uses those temperatures to calculate a deep tissue temperature. The measurement system includes a signal interface cable having a connector where a probe can be releasably connected to the system. The cable and attached connector are a removable and replaceable part of the system, separate from the probe. The measurement system provides an output signal imitating a standard input signal configuration used by other equipment. | 11-15-2012 |
20130003776 | Zero-Heat-Flux, Deep Tissue Temperature Measurement Devices with Thermal Sensor Calibration - A zero-heat-flux DTT measurement device is constituted of a flexible substrate supporting an electrical circuit including a heater trace defining a heater, thermal sensors, and a thermal sensor calibration circuit. | 01-03-2013 |
20130010828 | Constructions for Zero-Heat-Flux, Deep Tissue Temperature Measurement Devices - The invention pertains to flexible devices used for zero-heat-flux, deep tissue temperature measurement, especially to disposable temperature measurement devices. Such a device is constituted of a flexible substrate. An electrical circuit is disposed on a side of the substrate. The electrical circuit includes first and second thermal sensors disposed, respectively, on first and second substrate layers. A heater trace is disposed on the first substrate layer with the first thermal sensor. The first and second substrate layers are separated by a flexible layer of insulation disposed between the first and second substrate layers. The heater trace defines a heater with a central portion that operates with a first power density and a peripheral portion around the central portion that operates with a second power density greater than the first power density. | 01-10-2013 |
Patent application number | Description | Published |
20100217308 | LOCKING ELEMENT FOR VASCULAR CLOSURE DEVICE - In one illustrative example, a device for sealing an opening in a vessel wall and/or tissue tract may include an anchor, a filament, a plug, and a knot. The anchor may be configured to be disposed adjacent to an interior surface of the vessel wall adjacent the opening in the vessel wall. The filament may have a distal end coupled to the anchor and may be configured to extend proximally through the vessel opening and/or tissue tract. The plug may be disposed about at least a portion of the filament member. The knot may be disposed about the filament proximal of the plug and may be configured to move over the filament and secure the plug relative to the anchor. The knot may be independent of the filament member. | 08-26-2010 |
20100217309 | PLUG FOR ARTERIOTOMY CLOSURE AND METHOD OF USE - The disclosure provides a modified arteriotomy closure plug, said modification selected from the group consisting of a slit, a notch, a groove, and combinations thereof and a method of manufacturing the arteriotomy closure plug. | 08-26-2010 |
20100217312 | COMPOSITE PLUG FOR ARTERIOTOMY CLOSURE AND METHOD OF USE - The disclosure provides a composite arteriotomy closure plug, a method of manufacturing the composite arteriotomy closure plug, and a method for the use thereof. | 08-26-2010 |
20100275432 | LOCKING ELEMENT FOR VASCULAR CLOSURE DEVICE - In one illustrative example, a device for sealing an opening in a vessel wall and/or tissue tract may include an anchor, a filament, a plug, and a knot. The anchor may be configured to be disposed adjacent to an interior surface of the vessel wall adjacent the opening in the vessel wall. The filament may have a distal end coupled to the anchor and may be configured to extend proximally through the vessel opening and/or tissue tract. The plug may be disposed about at least a portion of the filament member. The knot may be disposed about the filament proximal of the plug and may be configured to move over the filament and secure the plug relative to the anchor. The knot may be independent of the filament member. | 11-04-2010 |
20130035719 | COMPOSITE PLUG FOR ARTERIOTOMY CLOSURE AND METHOD OF USE - A composite plug for arteriotomy closure, a method of manufacturing a composite plug for arteriotomy closure, and a method for the use of a composite plug for arteriotomy closure may include an elongate core member, and one or more layers disposed at least in part about the core member, where the composite plug has been partially compacted in a radial direction. The composite plug may include an outer member at least partially surrounding the core member. | 02-07-2013 |
20130131667 | DEFLECTABLE RENAL NERVE ABLATION CATHETER - Medical devices including catheters for renal nerve ablation and/or modulation as well as methods for making and using such devices are disclosed. An example catheter may, have a proximal region and a distal region. The catheter may be configured to shift between a first straightened configuration and a second deflected configuration. The catheter may also include an ablation member coupled to the distal region and a handle coupled to the proximal region. The handle may include an actuation member for shifting the catheter between the first configuration and the second configuration. A lock may be coupled to the handle that maintains the catheter in either the first configuration or the second configuration. | 05-23-2013 |
Patent application number | Description | Published |
20100274230 | Axial-Force Limiting Torque Wrench for Use with Implantable Medical Devices - Embodiments of the invention are related to tools for coupling leads to header assemblies for implantable medical devices, amongst other things. A wrench is configured so that if an axial force exceeding a first threshold is applied to a handle housing, then the housing handle will rotate with respect to a shaft. Other embodiments are also included herein. | 10-28-2010 |
20110082531 | SIDE MOUNT FEEDTHROUGH SYSTEM FOR SEALED COMPONENTS - The present subject matter provides apparatus and methods for manufacturing an encasement for a component of an implantable medical device having a main circuit board. The method includes forming an encasement aperture on a lateral side of the encasement. The lateral side of the encasement is adapted to be placed substantially parallel to a surface of the main circuit board. A feedthrough assembly is connected through the encasement aperture. The feedthrough assembly includes at least one terminal conductor at least partially passing through the encasement aperture. | 04-07-2011 |
20110230923 | FEEDTHROUGH SYSTEM FOR IMPLANTABLE DEVICE COMPONENTS - The present subject matter provides feedthrough or interconnect systems for components of an implantable medical device and methods for their manufacture. A feedthrough system includes a wire or nailhead having a protruded tip. The wire or nailhead extends from an aperture in an encasement of a first component and is connected to a terminal conductor adapted to electrically connect to circuitry within the encasement. A ribbon wire has a distal end adapted to electrically connect to a second component and a proximal end having a pattern adapted to fit to the protruded tip of the wire or nailhead to provide for subsequent attachment of the ribbon wire to the nailhead. | 09-22-2011 |
20120271387 | CANTILEVERED SPRING CONTACT FOR AN IMPLANTABLE MEDICAL DEVICE - Some examples of an electrical contact spring for an implantable medical device includes a housing, rigid and tubular in shape, defining a housing passage extending along a longitudinal axis, from a proximal portion including a proximal lip that defines a proximal opening, to a distal portion including a distal lip that defines a distal opening and a spring disposed in the housing, the spring tubular in shape and defining a spring passage concentric to the housing passage, the spring including: a distal ring portion disposed adjacent the distal portion of the housing and physically coupled to the housing, a plurality of spring elements coupled to and extending from the distal ring portion toward the proximal portion of the housing and a proximal ring portion disposed adjacent the proximal portion of the housing, cantilevered and suspended inside of and spaced apart from the housing by the plurality of spring elements. | 10-25-2012 |
20140075752 | FEEDTHROUGH SYSTEM FOR IMPLANTABLE DEVICE COMPONENTS - The present subject matter provides feedthrough or interconnect systems for components of an implantable medical device and methods for their manufacture. A feedthrough system includes a wire or nailhead having a protruded tip. The wire or nailhead extends from an aperture in an encasement of a first component and is connected to a terminal conductor adapted to electrically connect to circuitry within the encasement. A ribbon wire has a distal end adapted to electrically connect to a second component and a proximal end having a pattern adapted to fit to the protruded tip of the wire or nailhead to provide for subsequent attachment of the ribbon wire to the nailhead. | 03-20-2014 |
Patent application number | Description | Published |
20140011675 | AGRICULTURAL COMPOSITIONS AND APPLICATIONS UTILIZING MINERAL COMPOUNDS - Embodiments provide inorganic mineral chelated compositions, cobalt compounds and compositions, and treatment compositions, and methods of making and using them. Mineral chelated compositions and cobalt compounds have been shown to improve plant health, plant emergence, crop yield, and plant resistance to disease and drought. The compositions described herein can be applied directly to seeds, soil, or plants, or they can be incorporated with existing agricultural treatments and processes, reducing cost and time for farmers to implement the methods described herein. Accordingly, the compositions can be used as a seed treatment, or they can be broadcast on soil, tilled in soil, placed in-furrow, mixed with other fertilizers or chemicals, side-dressed in the field, used as foliar treatments, or combinations thereof. Such methods provide valuable micronutrients in a highly bioavailable form to plants and soil. | 01-09-2014 |
Patent application number | Description | Published |
20110213335 | HOLLOW MICRONEEDLE ARRAY AND METHOD - Rapid, high-volume, intradermal infusion with minimal pain, is achived by applying an array of 10 to 30 hollow microneedles having a length of greater than 100 um to less than 1 mm into the skin of a patient, with a microneedle spacing of no less than 1.5 mm on average between adjacent microneedles, and pumping greater than 200 uL of fluid through the hollow microneedles at a rate of greater than 20 uL/min. | 09-01-2011 |
20130123707 | AQUEOUS FORMULATIONS FOR COATING MICRONEEDLE ARRAYS - Aqueous formulations that include at least one active pharmaceutical ingredient; and at least one excipient, wherein the aqueous formulation has a viscosity of from 500 to 30,000 centipoise when measured at a shear rate of 100 s | 05-16-2013 |
20140066842 | MICRONEEDLE DEVICES AND METHODS - A medical device, comprising: an array of microneedles, and a coating disposed on the microneedles, wherein the coating comprises: a local anesthetic selected from the group consisting of lidocaine, prilocalne, and a combination thereof; and a local anesthetic dose-extending component selected from the group consisting of alpha 1 adrenergic agonists, alpha 2 adrenergic agonists, and a combination thereof; wherein the local anesthetic is present in an amount of at least 1 wt-% based upon total weight of solids in the coating, and wherein the dose-extending component/local anesthetic weight ratio is at least 0.0001; a medical device, comprising an array of dissolvable microneedles, the microneedles comprising: a dissolvable matrix material; at least 1 wt-% of a local anesthetic selected from the group consisting of lidocaine, prilocalne, and a combination thereof; and a local anesthetic dose-extending component selected from the group consisting of alpha 1 adrenergic agonists, alpha 2 adrenergic agonists, and a combination thereof; wherein the dose-extending component/local anesthetic weight ratio is at least 0.0001, and wherein wt-% is based upon total weight of solids in all portions of the dissolvable microneedles which contain the local anesthetic; a method of extending a topically delivered local anesthetic dose in mammalian tissue using the devices; and methods of making the devices are provided. | 03-06-2014 |
20140066843 | MICRONEEDLE DEVICES AND METHODS - A medical device, comprising: an array of microneedles, and a coating disposed on the microneedles, wherein the coating comprises: a local anesthetic selected from the group consisting of lidocaine, prilocaine, and a combination thereof; and a local anesthetic dose-extending component selected from the group consisting of tetracaine, ropivacaine, bupivacaine, procaine and a combination thereof; wherein the local anesthetic is present in an amount of at least 1 wt-% based upon total weight of solids in the coating, and wherein the local anesthetic and dose-extending component are in a non-eutectic weight ratio; a medical device, comprising an array of dissolvable microneedles, the microneedles comprising: a dissolvable matrix material; at least 1 wt-% of a local anesthetic selected from the group consisting of lidocaine, prilocaine, and a combination thereof; and a local anesthetic dose-extending component selected from the group consisting of tetracaine, ropivacaine, bupivacaine, procaine and a combination thereof; wherein the local anesthetic and dose-extending component are in a non-eutectic weight ratio, and wherein wt-% is based upon total weight of solids in all portions of the dissolvable microneedles which contain the local anesthetic; a method of extending a topically delivered local anesthetic dose in mammalian tissue using the devices; and methods of making the devices are provided. | 03-06-2014 |
Patent application number | Description | Published |
20080300515 | Focused Chest Compression System and Method of Using Same - A system and method are described which permits the directed application of a percussive force to the chest wall to loosen mucus. Airway clearance therapy can be provided by repeated application of air impulses transmitted through the device. The device receives air from an air compressor or pulsating therapy unit (PTU), and forces the air into a flexible membrane inside a cup-like cavity. The open side of the cup is where the membrane expands outwardly into contact the patient's chest when it receives pressure pulses. Rapidly repeated air impulses impact the chest to dislodge mucus adherent to airways within in the lungs. Strategic placement of the device permits focused treatment of affected lung regions. Administration of air impulses to the chest wall is continued until treatment is completed. A pressure sensor can be provided to ensure that the device is properly placed on the patient's body. | 12-04-2008 |
20090306556 | Chest Compression Apparatus Having Physiological Sensor Accessory - A chest compression system and method of use for respiratory therapies such as cystic fibrosis, including an air flow generator, a pulse frequency control component having a fan blade for producing a series of air pulses communicated to a patient-worn garment during a therapy session. The system further includes one or more patient physiologic sensors capable of capturing patient information during the therapy session. The sensors may include a blood oximeter or a mouthpiece used to evaluate pulmonary function. An airway congestion monitoring system provides airway and lung congestion trend analysis. Adjustments are made to the series of air pulses based on a patient's therapy session data. | 12-10-2009 |
20100242955 | Aerosolized Drug Delivery System - A system for delivering an aerosolized drug to a patient includes an aerosol drug generator coupled to a mouthpiece including two sensing ports. A pressure sensor is connected to the two sensing ports of the mouthpiece. The system also includes a data processing component which calculates an inspired flow rate based on a signal from the pressure sensor, and a measurement component which measures the inhalation time, which is the time during which the aerosolized drug is inhaled at the inspired flow rate. The data processing component also calculates the amount of the aerosolized drug delivered to the patient based on the inspired flow rate, the amount of inhalation time, and a drug delivery coefficient. | 09-30-2010 |
20100249634 | Mouthpiece and Airway Congestion Monitoring System - A congestion monitoring system includes a generally cylindrical, hollow form to channel a patient's breath, a flow restriction within the hollow form, and a pair of air ports. One of the air ports is located on the hollow form at a first side of the flow restriction, and the other air port is located on the hollow form at a second side of the flow restriction. The system also includes a coupling for connecting the pair of air ports to a pair of air lines, a sensor in communication with the air ports via the pair of air lines, and a monitor device. The monitor device converts a pressure signal from the air ports into a signal representative of a flow rate of the patient's breath through the hollow form. | 09-30-2010 |
20110125068 | Frequency Optimization for Chest Compression Apparatus - A high frequency chest compression system for deriving one or more frequencies for a therapeutically-beneficial treatment protocol based on pressure measurements made via a mouthpiece. A routine for identifying optimal operating frequencies for an air pulse generator is also provided. | 05-26-2011 |
Patent application number | Description | Published |
20090139394 | Self starting vibrator - Briefly, the invention comprises a vibrator with an on-demand start-up system, that inhibits fouling the atmosphere, with one embodiment of the invention including an integral non-fouling start-up system wherein at least one of the bearing surfaces contains a surface adhered lubricant so as to provide an on-demand static start-up system and in another embodiment the on-demand start-up system is a dynamic system that can unbalance the differential forces on the piston therein to ensure that the vibrator will begin vibrating “on-demand”. Thus, two types of start-up systems are available one an on-demand static start-up system and the other an on-demand dynamic start-up system with either of the systems can be used alone or if desired in combination to provide redundant start-up systems. | 06-04-2009 |
20140299803 | Butterfly Valve - A lightweight butterfly valve having a disk maintained in a fixed position on a compound shaft through an interlocking relation ship between each of the individual shafts of the compound shaft and the disk as the disk is moveable between an open or closed position with the butterfly valve may having other features such as an electric drive to quickly rotate the compound shaft to provide for rapid opening and closing the butterfly valve, a disk position indicator and a shaft stop to prevent the disk from being driven past a full open condition. | 10-09-2014 |
20160018006 | Butterfly valves - A lightweight butterfly valve having a disk maintained in a fixed position on a compound shaft through an interlocking relation ship between each of the individual shafts of the compound shaft and the disk as the disk is moveable between an open or closed position with the butterfly valve may having other features such as an electric drive to quickly rotate the compound shaft to provide for rapid opening and closing the butterfly valve, a disk position indicator and a shaft stop to prevent the disk from being driven past a full open condition. | 01-21-2016 |