Hampe
Christiane Hampe, Seattle, WA US
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20110052569 | MOLECULES AND METHODS FOR TREATMENT OF DIABETES - Described are antibodies that specifically recognize and bind the epitope of glutamate decarboxylase (GAD65) that is bound by antibody b96 11, and anti-idiotypic antibodies that are capable of competing with GAD65 for binding with b96.11 and competitively inhibit such binding. These antibodies can be provided in the form of a pharmaceutical composition and can be used in methods for delaying the onset of Type 1 diabetes and for inhibiting insulitis and other diabetic symptoms. Also provided are methods for detecting a susceptibility to Type 1 diabetes in a subject and for detecting the presence of anti-idiotypic antibodies to GAD65. The method comprises contacting a specimen with an antibody of the invention. The method further comprises detecting binding of the molecule of the specimen. The absence (or relative absence) of binding is indicative of susceptibility to Type 1 diabetes and of the absence of anti-idiotypic antibodies. | 03-03-2011 |
Christiane S. Hampe, Seattle, WA US
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20160032016 | MOLECULES AND METHODS FOR TREATMENT OF DIABETES - Described are antibodies that specifically recognize and bind the epitope of glutamate decarboxylase (GAD65) that is bound by antibody b96.11, and anti-idiotypic antibodies that are capable of competing with GAD65 for binding with b96.11 and competitively inhibit such binding. These antibodies can be provided in the form of a pharmaceutical composition and can be used in methods for delaying the onset of Type 1 diabetes and for inhibiting insulitis and other diabetic symptoms. Also provided are methods for detecting a susceptibility to Type 1 diabetes in a subject and for detecting the presence of anti-idiotypic antibodies to GAD65. The method comprises contacting a specimen with an antibody of the invention. The method further comprises detecting binding of the molecule to the specimen. The absence (or relative absence) of binding is indicative of susceptibility to Type 1 diabetes and of the absence of anti-idiotypic antibodies. | 02-04-2016 |
Cornelia Hampe, Plan-Les-Ouates CH
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20130035256 | Chimeric Polypeptides Useful in Proximal and Dynamic High-Throughput Screening Methods - The present invention provides a method of high-throughput screening (HTS) of active agents of a cell-surface G-Protein coupled receptor (GPCR) or another target receptor of interest. The method uses a non-invasive, sensitive reporting system that is proximal to the target of interest, combined with a dynamic, automated screening procedure so as to detect orthosteric ligands, such as agonists and antagonists, but is also suitable to detect allosteric or low affinity active agents of a GPCR and possibly other disease-related receptors. | 02-07-2013 |
Craig E. Hampe, San Jose, CA US
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20120113738 | Memory Device Having Multiple Power Modes - A memory device having a memory core is described. The memory device includes a clock receiver circuit, a first interface to receive a read command, a data interface, and a second interface to receive power mode information. The data interface is separate from the first interface. The second interface is separate from the first interface and the data interface. The memory device has a plurality of power modes, including a first mode in which the clock receiver circuit, first interface, and data interface are turned off; a second mode in which the clock receiver is turned on and the first interface and data interface are turned off; and a third mode in which the clock receiver and first interface are turned on. In the third mode, the data interface is turned on when the first interface receives the command, to output data in response to the command. | 05-10-2012 |
Jochen Hampe, Ville St-Laurent CA
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20100099083 | CROHN DISEASE SUSCEPTIBILITY GENE - The present invention relates to the ATG16l1 gene and genetic variants associated with Crohn's disease. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to Crohn's disease and/or their response to a particular drug or drugs. | 04-22-2010 |
Patrick Hampe, Bangkok TH
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20110291677 | METHOD AND APPARATUS FOR DEFECT DETECTION - A system for detecting a defect in a membranous article ( | 12-01-2011 |
Patrick Hampe, Singapore SG
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20100263695 | SYSTEM FOR THE PROCESSING OF REUSABLE GLOVES - A system for processing reusable gloves comprising a conveyor means ( | 10-21-2010 |