Patent application number | Description | Published |
20080292582 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE - Compounds of formula (I), combinations and uses thereof for disease therapy, | 11-27-2008 |
20100119475 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE - Compounds of general formula (I): | 05-13-2010 |
20100125086 | USE OF ISOQC INHIBITORS - The present invention relates in general to an inhibitor of a glutaminyl peptide cyclotransferase-like protein (QPCTL), and the use thereof for the treatment and/or prevention of an inflammatory disease or disorder selected from the group consisting of (a) chronic and acute inflammations, e.g. rheumatoid arthritis, atherosclerosis, restenosis, pancreatitis; (b) other inflammatory diseases, e.g. neuropathic pain, graft rejection/graft failure/graft vasculopathy, HIV infections/AIDS, gestosis, tuberous sclerosis, Guillain-Barré syndrome, chronic inflammatory demyelinising polyradiculoneuropathy and multiple sclerosis; (c) neuroinflammation; and (d) neurodegenerative diseases, e.g. mild cognitive impairment (MCI), Alzheimer's disease, neurodegeneration in Down Syndrome, Familial British Dementia, and Familial Danish Dementia, which may result from neuroinflammation. | 05-20-2010 |
Patent application number | Description | Published |
20090278423 | PIEZOELECTRIC ACTUATOR WITH GRADIENT ENCAPSULATION LAYER AND METHOD FOR THE PRODUCTION THEREOF - In a method for the production of a gradient encapsulation layer | 11-12-2009 |
20090302713 | PIEZO ACTUATOR COMPRISING A MULTILAYER ENCAPSULATION, AND METHOD FOR THE PRODUCTION THEREOF - In a method for producing a multilayer encapsulation ( | 12-10-2009 |
20100038456 | METHOD AND SYSTEM FOR SEPARATING A MULTIPLICITY OF CERAMIC COMPONENTS FROM A COMPONENT BLOCK - In a method for detaching a plurality of ceramic components ( | 02-18-2010 |
20100043769 | WIRE SAW AND METHOD FOR PRODUCING A WIRE SAW - A wire saw (S) for separating a plurality of ceramic components ( | 02-25-2010 |
20100102138 | PIEZOELECTRIC COMPONENT COMPRISING A SECURITY LAYER AND AN INFILTRATION BARRIER AND A METHOD FOR THE PRODUCTION THEREOF - A piezoelectric component with a monolithic stack, has electrode layers and piezoceramic layers arranged alternately one on top of the other, the piezoceramic layers have a piezoceramic, and having at least one porous security layer arranged in the stack for the formation of a crack if mechanical overload of the stack should occur. The piezoelectric component has an infiltration barrier arranged between the security layer and a lateral surface section of the stack for suppressing the penetration of a foreign substance into the security layer. The piezoelectric component can be as a piezoactuator for controlling a valve, particularly a valve of an internal combustion engine. | 04-29-2010 |
20100225204 | PIEZOELECTRIC STACK AND METHOD FOR PRODUCING A PIEZOELECTRIC STACK - A piezoelectric stack ( | 09-09-2010 |
20130248623 | Piezoelectric Component with Contact - A piezoelectric component, e.g., for use as an actuator of a fuel injection valve in a motor vehicle, may include a stack-shaped actuator body including a plurality of piezoelectric elements and inner electrode layers arranged in an alternating manner in a stacking direction, each inner electrode layer being connected alternately to one of two metalizations on an outer face of the stack in an electrically conductive manner. Each metalization is connected to an electrically conductive electrode structure via an electrically conductive contacting element (e.g., adhesive or solder). The stack-shaped actuator body has at least one predetermined breaking point, and the metalizations and/or the contacting elements have a recess in the region of the at least one predetermined breaking point. | 09-26-2013 |
20140145563 | Tubular Spring For Receiving And Pretensioning An Actuator - A tubular spring is provided for receiving and pretensioning a piezoelectric or magnetostrictive actuator of an actuator unit, e.g., for actuating a fuel injector valve in internal combustion engines, wherein the tubular spring comprises at least two types of recesses, each comprising different maximum lateral extensions in the longitudinal direction of the tubular spring. The tubular spring is designed to comprise a uniform load distribution about the circumference of the tubular spring even without welding the longitudinal sides thereof abutting one another. | 05-29-2014 |
Patent application number | Description | Published |
20110082253 | MODIFIED ELASTOMERIC POLYMERS - The invention provides a elastomeric polymer composition comprising the reaction product of at least the following: i) a living anionic elastomeric polymer; ii) a silane modifier compound represented by the Formula I or Formula 2: (RIO) | 04-07-2011 |
20110092646 | LOW CHLORIDE POLYBUTADIENE - Compositions comprising a coupled interpolymer such as polybutadiene which may be suitable for HIPS and ABS have been discovered. The coupled interpolymer composition comprises an interpolymer comprising one or more monomeric units derived from a diene wherein the coupled interpolymer composition is characterized by: (A) a halide content of less than about 30 ppm based on the total weight of the coupled interpolymer; (B) a molecular weight distribution of from about 1.6 to about 2.4; and (C) a vinyl content of from about 5 to about 15 weight percent based on the total weight of the coupled interpolymer. | 04-21-2011 |
20110178256 | STYRENE-BUTADIENE POLYMERS WITH STYRENE GRADIENT AND METHODS OF MAKING THE SAME - The invention provides a process for polymerizing a polymer comprising monomeric units derived from styrene and 1,3-butadiene, said process comprising: A) adding less than 60 weight percent of the total amount of the butadiene used in the polymerization, to a reactor comprising the total amount of styrene used in the polymerization and solvent; B) initiator to the reactor, and allowing the reaction to proceed for a time t; C) adding the remaining amount of butadiene to the reactor in two or more separate additions; and wherein for each burtadiene addition, the amount of subsequent butadiene added is less than, or equal to, the amount of butadiene added in the immediately prior addition; and wherein for each butadiene addition, the butadiene is added over a time, t | 07-21-2011 |
20120010356 | STYRENE BUTADIENE RUBBER WITH NOVEL STYRENE INCORPORATION - The present invention relates to improved compositions of SSBR rubber. The improved compositions exhibit sufficient or improved balance of characteristics such as rolling resistance, HBU, abrasion, grip, and/or tear. The compositions may be made in an efficient, cost-effective manner. | 01-12-2012 |
20130090440 | LOW VINYL STYRENE-BUTADIENE POLYMERS AND METHODS OF MAKING THE SAME - The invention provides a process for the continuous polymerization of a polymer comprising monomeric units derived from styrene and 1,3-butadiene, said process comprising:
| 04-11-2013 |
20130345379 | High Styrene High Vinyl Styrene-Butadiene Rubber and Methods for Preparation Thereof - A process for polymerization of a polymer containing monomeric units derived from a styrene monomer and a 1,3-butadiene monomer includes polymerizing the monomeric units in the presence of an initiator, a first polar agent, and a second polar agent. The first polar agent includes a structure (I): R | 12-26-2013 |
20140024767 | High Styrene High Vinyl Styrene-Butadiene Rubber and Methods for Preparation Thereof - A polymer has at least the following characteristics: (a) a block styrene content containing 4 to 6 styrene units from about 27 to about 50 weight percent based on total styrene content in the polymer; (b) a vinyl content from about 30 to about 80 weight percent based on total amount of polymerized 1,3-butadiene; and (c) a styrene content from about 40 to about 70 weight percent based on total weight of polymer. Processes for the polymerization of such a polymer, compositions containing such a pofymer, and articles containing at least one component formed from such a composition are described. | 01-23-2014 |
20140107286 | High Styrene High Vinyl Styrene-Butadiene Rubber with Narrow Molecular Weight Distribution and Methods for Preparation Thereof - A polymer having at least the following characteristics: (a) a block styrene content with more than 4 consecutive styrene units from about 40 to about 70 weight percent based on total styrene content in the polymer; (b) a vinyl content from about 25 to about 80 weight percent based on total amount of polymerized 1,3-diene; (c) a styrene content from about 20 to about 75 weight percent based on total weight of polymer; and (d) a molecular weight distribution (Mw/Mn) of 1.5 or less. | 04-17-2014 |
20140121319 | High Styrene High Vinyl Styrene-Butadiene Rubber With Narrow Molecular Weight Distribution And Methods For Preparation Thereof - A polymer having at least the following characteristics: (a) a block styrene content with more than 6 consecutive styrene units from about 15 to about 35 weight percent based on total styrene content in the polymer; (b) a vinyl content from about 25 to about 80 weight percent based on total amount of polymerized 1,3-diene; and (c) a styrene content from about 35 to about 75 weight percent based on total weight of polymer; and (d) a molecular weight distribution (Mw/Mn) of 1.5 or less. | 05-01-2014 |
20150086735 | Modified Polymer Compositions - A process for the continuous preparation of modified elastomeric polymers includes (i) providing and polymerizing at least one conjugated diene monomer and, optionally, one or more aromatic vinyl monomer in the presence of an anionic initiator and a compound according to Formula I, e.g. 2,2-di-(2-oxolanyl)propane or a derivative thereof, to provide a living anionic polymer; and (ii) adding a “sulfanylsilane” compound to the living anionic polymer. Elastomeric polymers obtainable according to the above process and compositions including the elastomeric polymer and, optionally, further constituents such as oil, filler and/or vulcanizing agent are described. A process for the preparation of a cross-linked elastomeric polymer that includes adding a vulcanizing agent to the elastomeric polymer, as well as articles and compositions that include the elastomeric polymer, the cross-linked elastomeric polymer or both are described. | 03-26-2015 |
Patent application number | Description | Published |
20100009979 | PHARMACEUTICALS CONTAINING FLUOROQUINOLONES - The invention relates to the use of quaternary ammonium compounds for preventing precipitations of fluoroquinolones from their solutions and to stable, tolerated pharmaceuticals which are particularly suitable for parenteral use and which contain, in dissolved form, a fluoroquinolone and a quaternary ammonium compound. | 01-14-2010 |
20100197571 | EXTRUDATES WITH IMPROVED TASTE MASKING - The invention relates to extrudates comprising one or more pharmaceutically active substances, where the extrudates have a strand diameter of 0.5 mm or less, and to the use of these extrudates for the manufacture of medicaments. | 08-05-2010 |
20100261688 | STABILIZATION OF OILY SUSPENSIONS COMPRISING HYDROPHOBIC SILICAS - The invention relates to a stabilization of fluid oil-based suspensions comprising a hydrophobic silica, and medicaments based on such suspensions. | 10-14-2010 |
20110263826 | ANTIBODIES WHICH BIND SELECTIVELY TO HAIR OF ANIMALS AND AN ANTIBODY BASED DRUG DELIVERY SYSTEM FOR ANIMALS - The present invention provides antibodies which bind selectively to hair of animals and an antibody based drug delivery system in which a particular formulation can be directed to animal hair. This is driven by the need of increasing the effective period of therapeutics for animal ectoparasites treatment, reducing the toxicity of these drugs and improving their release profile | 10-27-2011 |
20120034273 | EXTRUDATE HAVING SPICULAR ACTIVE SUBSTANCES - The invention relates to extrudates containing at least one pharmaceutically active substance in the form of needles, wherein the ratio of the particle size of the needle-shaped pharmaceutically active substance to the strand diameter is at least 1:15, and the use of these extrudates for the production of medicaments. | 02-09-2012 |
20130197006 | Non-Starch Based Soft Chewables - The present invention generally relates to soft chewables, especially suitable for delivering active ingredients to animals and processes for the preparation thereof. In various embodiments, the soft chewable comprises a pharmaceutically effective amount of at least one active ingredient, a flavoring agent, a disintegrant a humectant, an antioxidant, a preservative, and water. In accordance with preferred embodiments, the soft chewable is essentially free of starch, oil glycols, waxes, and soy products. | 08-01-2013 |
20140371139 | PREPARATIONS CONTAINING AMORPHOUS EMODEPSIDE - The invention relates to preparations comprising amorphous emodepside in a polyvinylpyrrolidone matrix, pharmaceuticals comprising such preparations, and their use against endoparasites in animals or humans. | 12-18-2014 |
Patent application number | Description | Published |
20120031823 | Apparatus for the Treatment of Wastewater - An apparatus for the treatment of wastewater, in particular aboard boats, with a treatment tank, which has a receiving portion and a treatment portion, an intake for wastewater in the receiving portion, an outlet on the treatment portion for treated wastewater, which is connected back into the treatment portion via a maceration pump with an intake for treated wastewater, wherein a separating wall with overflow is arranged between the receiving portion and the treatment portion, the receiving portion has a sump for solids and a connection for sea water and disinfecting agent is provided on the treatment portion, wherein a guide wall is arranged at a distance from the upper intake in the receiving portion, which ends above the sump and first directs the entering wastewater in the direction of the sump, the separating wall with a wall adjacent to the treatment portion forms an intermediate reservoir, to which the wastewater is added via the overflow, wherein the other wall has a second overflow to the treatment portion and the separating wall is designed as a flap, which in the open position connects the lower area of the intermediate reservoir with the sump. | 02-09-2012 |
20120103882 | Device for Clarifying Wastewater Preferably on Ships - A device for clarifying wastewater, preferably on ships, having the following features: A tank for untreated water is connected to a pressure tank via a macerator and a feed pump. The pressure tank is connected to a compressed air source so that the untreated water in the pressure tank is saturated with air. The pressure tank is connected via a line to a decompression tank in which the flotate and clarification water can be separated from each other. An expansion valve is inserted in the line, and a dosing pump for flocculant is connected to the line between expansion valve and decompression tank. | 05-03-2012 |