Guo, HK
Lei Guo, Hk HK
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20140213614 | Imaging Beta-Amyloid Peptides and Inhibition of Beta-Amyloid Peptide Aggregation - The present invention is in the field of pharmaceuticals and chemical industries. In particular, the present invention relates to methods for labeling, imaging and detecting the beta-amyloid (Aβ) peptides, oligomers, and fibrils in vitro by using carbazole-based fluorophores. A further aspect of the present invention relates to a method of reducing and preventing aggregation of beta-amyloid peptides for Alzheimer's disease (AD) as well as of treating and/or preventing Alzheimer's disease by using carbazole-based fluorophores. | 07-31-2014 |
Lei Guo, Hkust HK
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20140005411 | LOW BANDGAP DICYANOVINYL AND TRICYANOVINYL OLIGOTHIOPHENES FOR SOLAR CELL APPLICATIONS | 01-02-2014 |
Lei Guo, Hong Kong HK
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20140212360 | Imaging Beta-Amyloid Peptides and Inhibition of Beta-Amyloid Peptide Aggregation - The present invention is in the field of pharmaceuticals and chemical industries. In particular, the present invention relates to methods for labeling, imaging and detecting the beta-amyloid (Aβ) peptides, oligomers, and fibrils in vitro by using carbazole-based fluorophores. A further aspect of the present invention relates to a method of reducing and preventing aggregation of beta-amyloid peptides for Alzheimer's disease (AD) as well as of treating and/or preventing Alzheimer's disease by using carbazole-based fluorophores. | 07-31-2014 |
Qi Guo, Hong Kong HK
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20150029453 | STABILIZED PHOTO-ALIGNMENT LAYER FOR LIQUID CRYSTAL - A liquid-crystal photo-alignment layer that is composed of polymer stabilized azo dyes is provided, where a polymer network is introduced in the photo-alignment layer for stabilization. The photo-alignment layer is realized based on a two-step irradiation to first achieve molecule alignment to form the photo-alignment layer and then stabilize this layer. To realize the photo-alignment layer, a pre-determined surface of the substrate is first coated with a film of mixture. The mixture comprises an azo dye and a monomer preferably mixed in an optimal concentration of 0.67 wt/wt. The azo dye and the monomer have light-absorption peaks at different wavelengths such that photo-alignment of the azo-dye molecules and stabilization of the photo-alignment layer by polymerization of the monomer are achievable by two separate exposures of light to the film. | 01-29-2015 |
Xin Dong Guo, Hong Kong HK
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20130034589 | pH-SENSITIVE NANOPARTICLES FOR ORAL INSULIN DELIVERY - The present invention discloses the pH-sensitive nanoparticles composed of pH-sensitive polymer, hydrophobic material, internal stabilizer, external stabilizer content and insulin drug. The present invention also includes a method for preparation of pH-sensitive nanoparticles, in particular, a multiple emulsions solvent evaporation method. The pH-sensitive nanoparticles of the present invention show good pH-sensitive property with 100-300 nanometer particle size. Significant decrease in blood glucose level is observed in streptozotocin (STZ)-induced diabetic rats and the bioavailability of insulin is more than 10% after oral administration of the insulin-loaded pH-sensitive nanoparticles. | 02-07-2013 |
20130034602 | ENTERIC-COATED CAPSULE CONTAINING CATIONIC NANOPARTICLES FOR ORAL INSULIN DELIVERY - The invention relates to an enteric-coated capsule containing cationic nanoparticles for oral insulin delivery, in particular to a type of cationic nanoparticle including a polycationic and mucoadhesive polymer and a biodegradable polymer, wherein each of the nanoparticles has positive surface charge and enhanced permeability for paracellular insulin delivery; the enteric-coated capsule further includes a pH-sensitive polymer as the coating. The enteric-coated capsule containing cationic nanoparticles, when being orally administered to a subject, are configured to prevent the acidic degradation of the active substance such as insulin before being released from said cationic nanoparticles to a specific absorption site along the gastrointestinal tract. | 02-07-2013 |
Zheng-Wen Guo, Kwai Chung HK
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20150082538 | Reversible Child Holding Accessory - A child holding accessory includes a reversible resting support and at least one fixture for attaching the resting support with a rigid support frame. The reversible resting support has a first and a second bearing surface facing opposite directions, the first and second bearing surfaces respectively having different profiles, and each of the first and second regions being positionable to be upwardly facing to receive a child thereon. | 03-26-2015 |
Zheng-Wen Guo, Central Hong Kong HK
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20120086193 | Wheel Assembly for an Infant Carrier Apparatus - A wheel assembly for an infant carrier apparatus can include a shock absorber, and at least a wheel pivotally coupled with the shock absorber. Examples of the infant carrier apparatus can include an infant stroller apparatus. In some embodiments, the shock absorber can be directly connected with a support frame of the infant carrier apparatus. In other embodiments, the wheel assembly can include a mount base through which the shock absorber is connected with the support frame. | 04-12-2012 |
20130026804 | Child Safety Seat Assemblies Having Anchor Systems - A child safety seat assembly comprises a base, two connector arms assembled with the base, at least one latch assembled with the base and operable to lock the connector arms in position with the base, and at least a release actuator disposed between the connector arms and operatively connected with the latch. The connector arms are provided with locking fasteners operable to engage with an anchorage bracket in a vehicle to lock the base in place, the connector arms being movable relative to the base to adjust a length of extension of the connector arms outside the base. The release actuator is operable to drive an unlocking displacement of the latch to allow adjustment of the connector arms relative to the base. | 01-31-2013 |
20130307305 | Support Base for a Child Safety Seat - A support base for a child safety seat includes a shell body, an adjustable arm assembled with the shell body and having a rear end provided with a fastener operable to attach with an anchorage fixture of a vehicle, a safety lock, and a coupling portion assembled through an interior of the adjustable arm. The shell body is movable along the adjustable arm to adjust a distance between the fastener and a rear of the shell body. The safety lock is assembled with the shell body, and includes a latch operable to engage and disengage an opening of the adjustable arm. The latch is operable to lock the shell body with the adjustable arm, and a locking engagement of the fastener with the anchorage fixture causes a displacement of the coupling portion that pushes the latch to disengage from the opening for allowing displacement of the shell body toward the fastener. | 11-21-2013 |
20140035333 | Base for Child Safety Carrier - A base suitable for use with a child safety carrier includes a shell body, a platform movably assembled with the shell body, a latch mechanism and a plurality of cushion structures. The latch mechanism includes a holding frame and a latch, the holding frame being affixed with one of the shell body and the platform, and the latch being assembled with the other one of the shell body and the platform. The holding frame includes locking openings, and the latch is operable to engage with any of the locking openings to lock the platform with the shell body. The cushion structures are respectively disposed adjacent to the locking openings. When collision occurs, the latch can interact with one of the cushion structures to cause deformation or break of the cushion structure so that the platform is displaced relative to the shell body. | 02-06-2014 |
Zhen-Wen Guo, Central Hong Kong HK
Patent application number | Description | Published |
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20130277933 | Wheel Assembly for an Infant Carrier Apparatus - A wheel assembly for an infant carrier apparatus can include a shock absorber, and at least a wheel pivotally coupled with the shock absorber. The shock absorber is formed integrally in a single body comprising a cushion structure capable of elastic deformation, and a mount structure having a tubular shape adapted to assemble with a support frame of an infant carrier apparatus. Examples of the infant carrier apparatus can include an infant stroller apparatus. | 10-24-2013 |