| Patent application number | Description | Published |
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| 20100282984 | DEVICE AND METHOD FOR THE CONTACTLESS MANIPULATION AND ALIGNMENT OF SAMPLE PARTICLES IN A MEASUREMENT VOLUME USING A NONHOMOGENEOUS ELECTRIC ALTERNATING FIELD - The invention relates to a device for contactless manipulation and alignment of sample particles in a measurement volume using a nonhomogeneous electric alternating field, comprising a radiation source for emitting electromagnetic radiation and optical means for guiding the electromagnetic radiation into the measurement volume. The device is characterized in that the optical means include a beam shaping device for generating an intensity profile that is asymmetrical about the beam axis, wherein sample particles in the measurement volume can be trapped in a nonhomogeneous field distribution of the electric field generated by the asymmetrical intensity profile, that for the purpose of entraining sample particles trapped in the nonhomogeneous field distribution there is provided a rotating device to effect rotation of the asymmetrical intensity profile about the beam axis relatively to the measurement volume, and that the electromagnetic radiation beam in the measurement volume is unfocused, more particularly, divergent. The invention further relates to a method for contactless manipulation and alignment of sample particles in a measurement volume using a nonhomogeneous electric field. | 11-11-2010 |
| 20130316390 | Method for diagnosis and/or prognosis of cancers by analysis of the mechanical properties of tumour cells - A method for diagnosis and/or prognosis of cancers, for diagnosis of the site of origin of tumour cells, for optimizing the treatment of cancer patients and for screening active substances for oncology. In the method, the mechanical properties of tumour cells and reference cells are analyzed under a mechanical load that leads to linear or nonlinear deformation of the respective loaded cell. The expansion of the cells, which results from the input of a directed mechanical stress, is used to determine the risk of tumour metastases and, if appropriate, the presence of uncontrollably proliferating and/or invasive cells, or the tissue of origin of the tumour. The risk of tumour metastases is determined on the basis of the proportion of cells in the sample that have an extension counter to the direction of stressing. The risk of the presence of uncontrollably proliferating cells is determined, in the case of nonlinear deformation of the cell, on the basis of the mean value of the expansion in the direction of stressing of cells in the sample. | 11-28-2013 |
| Patent application number | Description | Published |
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| 20100011337 | OPEN APPLICATION LIFECYCLE MANAGEMENT FRAMEWORK DOMAIN MODEL - Techniques for an open application lifecycle management framework domain model are described, including evaluating data retrieved from an application in data communication with a framework hosted by a computer, identifying an element associated with the data and another element associated with the framework, creating a common data representation associated with the element, wherein the common data representation is generated according to a domain model associated with the framework, and generating a map associating the common data representation to the element and another element associated with the framework. | 01-14-2010 |
| 20100017792 | OPEN APPLICATION LIFECYCLE MANAGEMENT FRAMEWORK - Techniques for open application lifecycle management frameworks are described, including using a framework hosted on one or more computers and having one or more services to integrate the one or more services with one or more applications using one or more providers, each of the one or more providers is adapted to at least one of the one or more applications, registering one or more repositories associated with the one or more applications using a location service module, receiving an input creating a project context associated with a project, data associated with the input being stored in a data structure associated with the project, the data structure being stored in a repository associated with the framework, generating a link, after registering the one or more repositories, between one or more element containers associated with the project, the link and the one or more element containers being stored in the repository, and configuring the framework to detect another input indicating interaction with an artifact, other data associated with the interaction being mapped between the one or more repositories and the repository using a domain model. | 01-21-2010 |
| 20140101632 | OPEN APPLICATION LIFECYCLE MANAGEMENT FRAMEWORK - Techniques for open application lifecycle management frameworks are described, including using a framework hosted on one or more computers and having one or more services to integrate the one or more services with one or more applications using one or more providers, each of the one or more providers is adapted to at least one of the one or more applications, registering one or more repositories associated with the one or more applications using a location service module, receiving an input creating a project context associated with a project, data associated with the input being stored in a data structure associated with the project, the data structure being stored in a repository associated with the framework, generating a link, after registering the one or more repositories, between one or more element containers associated with the project, the link and the one or more element containers being stored in the repository, and configuring the framework to detect another input indicating interaction with an artifact, other data associated with the interaction being mapped between the one or more repositories and the repository using a domain model. | 04-10-2014 |
