Patent application number | Description | Published |
20090326584 | Spinal Dynamic Stabilization Rods Having Interior Bumpers - A dynamic stabilization device for use in the human spine, comprising i) a hollow, closed-end cylinder component that is configured for attachment to a first pedicle screw, ii) a solid rod component that is configured on one end to slide freely within the hollow cylinder component, and configured at the other end for attachment to a second pedicle screw and iii) an elastomer component contained within the hollow cylinder and located between the closed end of the hollow cylinder and the end of the solid rod component. | 12-31-2009 |
20090326657 | Pliable Artificial Disc Endplate - An intervertebral implant for replacing an intervertebral disc of the human spine, the implant including first and second conformable foam endplates, each endplate being conformable to a boney vertebral endplate under an anatomical load, and a core between the endplates, wherein the conformable foam endplates partition the core from the boney vertebral endplate so that the core does not contact the boney vertebral endplate. | 12-31-2009 |
20100249935 | Zero Profile Spinal Fusion Cage - An interbody fusion cage having upper and lower canals for receiving the heads of bone screws that have been pre-installed in opposing vertebral body endplates. The proximal wall of the cage preferably has a vertical slot that communicates with each canal and is adapted to allow access by a screwdriver and tightening of the screws. | 09-30-2010 |
20110144700 | RESILIENT BONE PLATE AND SCREW SYSTEM ALLOWING BI-DIRECTIONAL ASSEMBLY - Bone screws and bone plates are provided that offer the surgeon the ability to either assemble the screws to the plate, or the plate to the screws, depending on the surgeon's preference and the patient's circumstances. The bone screws and bone plates of the present invention include a combination of geometric configurations that allow the screws and plates to fit together from different assembly directions. Additionally, the bone screws and bone plates can include material resilience features to allow expansion/contraction during assembly to allow bidirectional attachment to one another. | 06-16-2011 |
20130053886 | SYSTEM AND METHOD FOR CERVICAL MIDLINE FIXATION - Devices and methods for enhancing the effectiveness of spinal stabilization, and particularly that of cervical spinal stabilization, are provided herein. More specifically, methods and systems are disclosed for effectively positioning occipital plates and spinal fixation assemblies within target vertebrae, while also reducing any associated patient trauma (e.g., muscle stripping, tissue damage, etc.). The systems and methods can utilize trans-lamina delivery of the spinal fixation assemblies to allow for the positioning of the fixation elements along the midline of the patient's spine. | 02-28-2013 |
20130053891 | REVISABLE ORTHOPEDIC ANCHOR AND METHODS OF USE - A revisable orthopedic anchor and method of use for removably securing an anchor in bone, such as compromised or degenerated bone, is described herein. In one embodiment, the anchor makes use of dual probes and vector divergence of the distal tips of the probes to achieve superior bone purchase and pull-out resistance. In such an embodiment, the probes can be inserted one at a time into a hole formed in, for example, the pedicle bone. After the probes are inserted and joined at the proximal end, they have a greater pull-out resistance than a threaded anchor. Removing the anchor involves separating the proximal heads and reversing the implantation process. As a result of the unique bone anchor design disclosed herein, the devices and methods of the present invention allow for less complicated implantation and removal of orthopedic anchors, all while providing enhanced bone purchase when implanted in a patient. | 02-28-2013 |
20130053892 | SYSTEM AND METHOD FOR CERVICAL MIDLINE FIXATION - Devices and methods for enhancing the effectiveness of spinal stabilization, and particularly that of cervical spinal stabilization, are provided herein. More specifically, methods and systems are disclosed for effectively positioning occipital plates and spinal fixation assemblies within target vertebrae, while also reducing any associated patient trauma (e.g., muscle stripping, tissue damage, etc.). The systems and methods can utilize trans-lamina delivery of the spinal fixation assemblies to allow for the positioning of the fixation elements along the midline of the patient's spine. | 02-28-2013 |
20130109925 | Method and Devices For A Sub-Splenius / Supra-Levator Scapulae Surgical Access Technique | 05-02-2013 |
20140243908 | RESILIENT BONE PLATE AND SCREW SYSTEM ALLOWING BI-DIRECTIONAL ASSEMBLY - Bone screws and bone plates are provided that offer the surgeon the ability to either assemble the screws to the plate, or the plate to the screws, depending on the surgeon's preference and the patient's circumstances. The bone screws and bone plates of the present invention include a combination of geometric configurations that allow the screws and plates to fit together from different assembly directions. Additionally, the bone screws and bone plates can include material resilience features to allow expansion/contraction during assembly to allow bidirectional attachment to one another. | 08-28-2014 |
Patent application number | Description | Published |
20110313281 | Instrument for Image Guided Applications - A trackable medical instrument for use in a computer assisted image guided surgery system having a digitizer for tracking the position of the instrument in three dimensional space and a display providing an indication of the position of the instrument with respect to images of a body part taken preoperatively, wherein the instrument comprises a tracking array located distally of a rotatable, axially fixed drive handle. | 12-22-2011 |
20110319995 | Enhanced Cage Insertion Device - A method of delivering a fusion cage to an intervertebral disc space bounded by adjacent vertebral endplates, comprising the step of delivering the fusion cage into the disc space without contacting its teeth to the vertebral endplates during delivery, wherein a sheath is interposed between a cage surface and the endplates to prevent contact therebetween during delivery. | 12-29-2011 |
20110320000 | Multi-Segment Lateral Cage Adapted to Flex Substantially in the Coronal Plane - The present invention concerns several fusion devices and methods for laterally inserting a fusion device at an initial trajectory that is not parallel to the disc space. Each fusion device incorporates components that enable flexing, bending or pivoting of the device during its final approach to the prepared disc space. | 12-29-2011 |
20120265210 | Vertebroplasty Curved Needle - Devices, systems and methods for delivering a curable, stabilizing material into a central region of a bone structure. Precise placement of the curable substance into a central region of a bone structure through a unipedicular approach. One primary advantage is its ability to create a central cavity in a vertebral body (or to centrally deliver bone cement) through a unipedicular approach. A curved needle having increased rigidity in its flexible end when the end is disposed in its straight position. This increased rigidity is due to a novel tensioning mechanism and to a segmented tube design (as opposed to the conventional longitudinally-slotted tube design). | 10-18-2012 |
Patent application number | Description | Published |
20100073145 | RFID Reaction Time Reduction - A method, system, and a control device are provided for reducing RFID reaction times. A control unit receives a data signal, which comprises a code signal if a passive RFID transponder is located in the carrier field of an RFID reader. The code represents the identification code of the passive RFID transponder. The carrier field is disabled to reset the data signal, and thereafter enabled to receive a first portion of the code signal only. The code of the passive RFID transponder is then validated on the basis of said first portion of the code signal only. | 03-25-2010 |
20120081106 | DOUBLE-COIL INDUCTIVE PROXIMITY SENSOR APPARATUS - Systems and/or methods are provided for a dual-channel inductive proximity sensor. The sensor can include a sensing element which includes a core having a first cavity and a second cavity, a first coil accommodated within the first cavity of the core, and a second coil housed within the second cavity of the core. Each coil can be independently driven by oscillators to generate respective magnetic fields. The magnetic fields can be monitored to determine whether detection of a target object occurs. | 04-05-2012 |
20120326842 | System and Method for Extending Range of Radio Frequency Identification (RFID) Signal Communications - Systems and methods for extending the range of radio frequency identification (RFID) signal communications, including related sensing systems, are disclosed. In one embodiment, the system facilitates wireless communications between a RFID reader device and RFID transponder device and includes an extender circuit. The extender circuit includes a first tank circuit including a first inductor connected in parallel with a first capacitor between first and second nodes, and a second tank circuit including a second inductor connected in parallel with a second capacitor between third and fourth nodes. The extender circuit includes a first connection including a resistor, the first connection linking the first and third nodes, and a second connection between the second and fourth nodes, where the second and fourth nodes are at or substantially at a common voltage. In at least some additional systems, the extender circuit is implemented in combination with an RFID reader or transponder device. | 12-27-2012 |
20130127599 | DETERMINING OPERATIONAL STATE WITH TAGS - Systems and methods are provided relating to utilizing a plurality of RFID tags in conjunction with a circuit comprising at least one reed switch to facilitate determination of operational states and actions based thereon. A magnet can activate the reed switch causing a first RFID tag to be activated and transmit an associated RFID identifier from which a position/operation associated with the first RFID can be determined. The magnet can be removed to activate a second RFID tag whereupon a second RFID identifier is transmitted from which a second position/operation can be determined. The circuit comprising the reed switch and RFID tags can have an induction coil enabling the circuit to be activated when the induction coil is brought into proximity of a second induction coil and inductively coupled. | 05-23-2013 |
Patent application number | Description | Published |
20130214167 | System to Test Performance of Pixels in a Sensor Array - A system to test operation of an optical sensor is disclosed. The optical sensor includes one or more photosensitive devices configured to convert light to electrical signals. A test light source and a reference target are included within the housing of the optical sensor. The test light source is mounted proximate to the photosensitive devices and the reference target is positioned opposite from the test light source. The test light source is periodically pulsed on to emit light at a known wavelength. The light is reflected from the reference target back to at least a portion of the photosensitive devices. A logic circuit uses the reflected light which is received at the portion of the photosensitive devices to determine the distance between the light source and the reference target. This calculated distance is compared against the known distance to verify correct operation of the optical sensor. | 08-22-2013 |
20130215418 | System to Detect Failed Pixels in a Sensor Array - A system to test operation of an optical sensor is disclosed. The optical sensor includes one or more photosensitive devices configured to convert light to electrical signals. A test light source is included within the housing of the optical sensor. The test light source is periodically pulsed on to emit radiation at a sufficient intensity to saturate each of the photosensitive devices. Each of the photosensitive devices generates a signal corresponding to the intensity of light detected at that device. A logic circuit uses the signals corresponding to the intensity of light to identify whether each of the photosensitive devices is performing at an acceptable level. | 08-22-2013 |
20130270422 | Method and Apparatus for a Dual Matrix Sensor Array - The subject matter disclosed herein describes an optical sensor used in a safety system. The sensor includes two pixel matrices on a single substrate. Each of the pixel matrices are arranged in a row and column format, and pixels from one matrix are interspersed with pixels from the other matrix such that alternating pixels in each row and column belong to separate matrices. Two sets of selection logic allow each matrix to be enabled separately. Additional monitoring logic is included to detect shorted pixels and/or shorted selection lines. In addition, the frames generated by each pixel array may be compared to detect variation in performance between arrays. | 10-17-2013 |
20150041626 | Method and Apparatus for Control of a Dual Matrix Sensor Array - The subject matter disclosed herein describes an optical sensor used in a safety system. The sensor includes two pixel matrices on a single substrate. Each of the pixel matrices are arranged in a row and column format, and pixels from one matrix are interspersed with pixels from the other matrix such that alternating pixels in each row and column belong to separate matrices. Two sets of selection logic allow each matrix to be enabled separately. Additional monitoring logic is included to detect shorted pixels and/or shorted selection lines. In addition, the frames generated by each pixel array may be compared to detect variation in performance between arrays. | 02-12-2015 |
Patent application number | Description | Published |
20130039910 | METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS AND PERICYTE COMPOSITION - In certain aspects, the present disclosure relates to the insight that a polypeptide comprising a ligand-binding portion of the extracellular domain of activin-like kinase I (ALK1) polypeptide may be used to inhibit angiogenesis in vivo, particularly in mammals suffering angiogenesis-related disorders. Additionally, the disclosure demonstrates that inhibitors of ALK1 may be used to increase pericyte coverage in vascularized tissues, including tumors and the retina. The disclosure also identifies ligands for ALK1 and demonstrates that such ligands have pro-angiogenic activity, and describes antibodies that inhibit receptor-ligand interaction. | 02-14-2013 |
20130040896 | METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS AND PERICYTE COMPOSITION - In certain aspects, the present disclosure relates to the insight that a polypeptide comprising a ligand-binding portion of the extracellular domain of activin-like kinase I (ALK1) polypeptide may be used to inhibit angiogenesis in vivo, particularly in mammals suffering angiogenesis-related disorders. Additionally, the disclosure demonstrates that inhibitors of ALK1 may be used to increase pericyte coverage in vascularized tissues, including tumors and the retina. The disclosure also identifies ligands for ALK1 and demonstrates that such ligands have pro-angiogenic activity, and describes antibodies that inhibit receptor-ligand interaction. | 02-14-2013 |
20130108650 | ACTRIIB BINDING AGENTS AND USES THEREOF | 05-02-2013 |
20130189269 | ACTRIIB BINDING AGENTS AND USES THEREOF - The disclosure provides, among other aspects, neutralizing antibodies and portions thereof that bind to ActRIIB and uses for same. | 07-25-2013 |
20130344067 | ALK1 RECEPTOR AND LIGAND ANTAGONISTS AND USES THEREOF - In certain aspects, the present disclosure relates to the insight that a polypeptide comprising a ligand-binding portion of the extracellular domain of activin-like kinase I (ALK1) polypeptide may be used to inhibit angiogenesis in vivo, particularly in mammals suffering angiogenesis-related disorders. The disclosure also identifies ligands for ALK1 and demonstrates that such ligands have pro-angiogenic activity, and antibodies that inhibit receptor-ligand interaction. | 12-26-2013 |
20150030606 | ACTRIIB BINDING AGENTS AND USES THEREOF - The disclosure provides, among other aspects, neutralizing antibodies and portions thereof that bind to ActRIIB and uses for same. | 01-29-2015 |
20150056199 | TGF-BETA RECEPTOR TYPE II VARIANTS AND USES THEREOF - In certain aspects, the present disclosure relates to polypeptides comprising a truncated, ligand-binding portion of the extracellular domain of TβRII polypeptide useful to selectively antagonize a TβRII ligand. The disclosure further provides compositions and methods for use in treating or preventing TGFβ associated disorders. | 02-26-2015 |
Patent application number | Description | Published |
20090082270 | Uses of cerberus, Coco and derivatives thereof - The disclosure relates to Cerberus/Coco polypeptides or variants thereof for use in treating a variety of disorders associated with myostatin, nodal and GDF-11. | 03-26-2009 |
20090304691 | ANTAGONISTS OF BMP9, BMP10, ALK1 AND OTHER ALK1 LIGANDS, AND USES THEREOF - In certain aspects, the present disclosure relates to the insight that a polypeptide comprising a ligand-binding portion of the extracellular domain of activin-like kinase I (ALK1) polypeptide may be used to inhibit angiogenesis in vivo, particularly in mammals suffering angiogenesis-related disorders. In certain aspects, the disclosure demonstrates that antagonists of BMP9 and/or BMP10, ligands for ALK1, may also be used to inhibit angiogenesis in vivo. | 12-10-2009 |
20090311272 | METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS AND PERICYTE COMPOSITION - In certain aspects, the present disclosure relates to the insight that a polypeptide comprising a ligand-binding portion of the extracellular domain of activin-like kinase I (ALK1) polypeptide may be used to inhibit angiogenesis in vivo, particularly in mammals suffering angiogenesis-related disorders. Additionally, the disclosure demonstrates that inhibitors of ALK1 may be used to increase pericyte coverage in vascularized tissues, including tumors and the retina. The disclosure also identifies ligands for ALK1 and demonstrates that such ligands have pro-angiogenic activity, and describes antibodies that inhibit receptor-ligand interaction. | 12-17-2009 |
20110046057 | USES OF CERBERUS AND DERIVATIVES THEREOF - The disclosure relates to Cerberus/Coco polypeptides or variants thereof for use in treating a variety of disorders associated with myostatin, nodal and GDF-11. | 02-24-2011 |
Patent application number | Description | Published |
20130325023 | Methods and Devices for Anchoring a Graft to Bone - Methods and devices are provided for anchoring graft to bone. In one exemplary embodiment, a bone cavity is created in bone, a graft is partially advanced into the bone cavity, and a hardenable filler material is inserted into the cavity. The hardenable filler material can change from a viscous first state to a harder second state, compressing the graft against the walls of the bone cavity and thereby anchoring the graft within the cavity. The hardenable filler material can be inserted in an open sac, a closed sac, other carriers or housings, or directly into the bone cavity. | 12-05-2013 |
20150073446 | Methods and Devices for Anchoring a Graft to Bone - Methods and devices are provided for anchoring graft to bone. In one exemplary embodiment, a bone cavity is created in bone, a graft is partially advanced into the bone cavity, and a hardenable filler material is inserted into the cavity. The hardenable filler material can change from a viscous first state to a harder second state, compressing the graft against the walls of the bone cavity and thereby anchoring the graft within the cavity. The hardenable filler material can be inserted in an open sac, a closed sac, other carriers or housings, or directly into the bone cavity. | 03-12-2015 |