Goldstein, MA
David Brian Goldstein, Groton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20140051938 | Device to detect and treat Apneas and Hypopnea - A method and apparatus for the treatment of Sleep Apnea events and Hypopnea episodes wherein one embodiment comprises a wearable, belt like apparatus containing a microphone and a plethysmograph. The microphone and plethysmograph generate signals that are representative of physiological aspects of respiration, and the signals are transferred to an imbedded computer. The embedded computer extracts the sound of breathing and the sound of the heart beat by Digital Signal Processing techniques. The embedded computer has elements for determining when respiration parameters falls out of defined boundaries for said respiration parameters. This exemplary method provides real-time detection of the onset of a Sleep Apnea event or Hypopnea episode and supplies stimulation signals upon the determination of a Sleep Apnea event or Hypopnea episode to initiate an inhalation. In one embodiment, the stimulus is applied to the patient by a cutaneous rumble effects actuator and/or audio effects broadcasting. | 02-20-2014 |
Gene H. Goldstein, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100035501 | THERMAL SPRAY MASKING TAPE - A thermal spray masking tape includes a substrate having a first major surface and a second major surface and a surface layer overlying the first major surface of the substrate. The surface layer is formed from an elastomer having an ultimate tensile strength greater than about 600 lbs/square inch. | 02-11-2010 |
| 20110070795 | THERMAL SPRAY MASKING TAPE - A thermal spray masking tape includes a substrate having a first major surface and a second major surface. The thermal spray masking tape further includes a surface layer overlying the first major surface of the substrate. The surface layer is formed from an elastomer including a liquid silicone rubber. | 03-24-2011 |
James A. Goldstein, Weston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20150018136 | CARBON FIBER OR FIBERGLASS LACROSSE HEAD - A method of making a lacrosse head is provided. The method includes providing a lacrosse head design to a 3D printer, providing a first printing material to the 3D printer, the first printing material including carbon fiber or fiberglass, and printing the lacrosse head with the 3-D printer using the lacrosse head design and the printing material. | 01-15-2015 |
Jay Goldstein, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090176719 | COMPOSITIONS AND METHODS FOR TREATING PERIORAL DERMATITIS - Methods for treating perioral dermatitis are described herein. The method includes administering topically a composition containing an effective amount of a systemic or topical antibiotic and a corticosteroid. The concentration of the antibiotic is from about 0.01% to about 5% by weight of the composition and the concentration of the corticosteroid is from about 0.01% to about 5% by weight of the composition. The composition can contain one or more pharmaceutically acceptable excipients and/or carriers. The compositions can be formulated as a lotion, cream, gel, ointment, paste, powder, solution, suspension, spray, foam, or patch. | 07-09-2009 |
Jay A. Goldstein, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080317830 | Compositions and Methods for the Treatment of Wounds and Scar Tissue - Compositions for the treatment of wounds and/or scars are described herein. The compositions contain between 1 and up to 30% by weight, more preferably between 1 and 20%, most preferably between about 5 and 10% by weight particles, such as titanium dioxide or a similar material in a pharmaceutically acceptable base or carrier, such as petrolatum. The compositions are less greasy than petrolatum alone, and thus are more aesthetically pleasing. The compositions exhibit occlusive properties comparable to petrolatum. The compositions are absorbed into the skin, unlike petrolatum, and exhibit significant wound healing characteristics not observed with petrolatum alone. In one embodiment, the pharmaceutically acceptable base is petrolatum and the particles are titanium dioxide. The compositions can be used to treat complex, hard to heal wounds, such as diabetic ulcers; pressure sores, such as bed sores; lacerations; bite wounds; burns; penetrating wounds; surgical wounds, etc. The composition can also be used to promote normal healing of scar tissue. The compositions can also be used for the topical delivery of one or more active agent. The compositions can be used to reduce fine lines and wrinkles, and to rehydrate skin or to treat dry skin. | 12-25-2008 |
| 20120165302 | ANTIFUNGAL FORMULATIONS - A topical composition and the method using the composition, which contains an antifungal agent and a low potency anti-inflammatory steroid which is safe and effective such as desonide or its derivative. The low potency steroid agent does not cause side effects such as skin atrophy, striae and hypopigmentation. The composition can be formulated in a dosage form such as a cream, ointment, gel, lotion, foam, powder, aerosol, spray, shampoo, or liquid solution. The composition can be used to treat a fungal disease such as tinea pedis, tinea capitis, tinea corporis, tinea versicolor, tinea cruris, and candidiasis as well as intertriginous dermatitis complicated by candidiasis. | 06-28-2012 |
Jonah Goldstein, Bringhton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110083090 | Apparatus and method for creating and using documents in a distributed computing network - An authoring application for allowing users to create, control and distribute electronic content including a canvas interface for constructing a project of the electronic content from a plurality of resource files, the canvas interface having: a canvas area for constructing screen elements of the selected resource files to create screens; a path area for illustrating a relationship among the screens of the project; and a properties area for adjusting characteristics of the selected screen elements, a reader interface for allowing the users to view the project, the reader interface being accessible from the canvas interface and a resource interface for managing groups, membership in groups, and user accounts, said groups and user accounts having varying levels of control over the project. | 04-07-2011 |
Keith Goldstein, Framingham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20140180918 | STORED-VALUE CARD SYSTEM - A hybrid stored-value card system is designed to support and effectively link uniquely designed physical stored-value cards with digital stored-value cards. Each physical stored-value card is preferably provided with a unique mobile link code that can be retrieved by a mobile device using automated means of data capture. The link code is transmitted to a server in direct communication with the mobile device along with certain pre-defined user information, such as the card owner name, email address and mobile number. The server utilizes the link code to create a corresponding digital stored-value card that can be downloaded and installed onto the mobile device in a format and design as specified by the card issuer. Using the user information, the server is able to maintain a direct communication path with the mobile device and thereby provide real-time notifications and updates to the card owner. | 06-26-2014 |
Keith E. Goldstein, Framingham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100276495 | TRANSACTION CARD ASSEMBLY AND METHODS OF MANUFACTURE - A transaction card assembly may be constructed and arranged for use in a transaction by an issuee of the transaction card assembly. The transaction card assembly may include a first layer including a sheet of material, a second layer including a sheet of material, and an adhesive foam material between the first and second layers that expands to fill a space between the first and second layers and to define, at least in part, a finished thickness for the transaction card assembly and bonds the first and second layers together. Indicia, such as information representing an account number, biometric data representing a feature of the issuee, etc., may be included with the assembly for use in a transaction. | 11-04-2010 |
| 20100279101 | COMPOSITES PRODUCED FROM SPRAYABLE ELASTOMERIC POLYURETHANE FOAM - The present invention relates to a composite containing a first plastic layer, a second plastic layer and a sprayable elastomeric polyurethane foam made from the reaction product of at least one isocyanate, at least one polyol and water, optionally at least one of blowing agents, surfactants, cross-linking agents, extending agents, pigments, flame retardants, catalysts and fillers, wherein the sprayable elastomeric polyurethane foam is sprayed onto one surface of the first plastic layer and expands to contact and adhere to one surface of the second plastic layer which is oriented parallel to the one surface of the first plastic layer and wherein the sprayable elastomeric polyurethane foam has a free rise density of from about 5 lb/ft | 11-04-2010 |
| 20100295286 | Cover and method of manufacturing the same - An electronic cover for a passport, booklet or the like includes an electronic device and a layer of cover material that are bonded together by a fill-up adhesive layer, the electronic device preferably being in the form of an RFID inlay that includes a substrate, an antenna coupled to the substrate and an integrated circuit (IC) chip module conductively coupled to the antenna. During manufacture of the cover, the fill-up adhesive layer is applied to at least one of the electronic device and the layer of cover material. Immediately thereafter, the electronic device and the layer of cover material are held spaced apart from one another a predefined distance so as to define a void therebetween. Through a suitable trigger, the fill-up adhesive layer expands to fill in the entire void and subsequently cures to bond the electronic device to the layer of cover material. | 11-25-2010 |
Lee E. Goldstein, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090041666 | Ophthalmic formulations of Amyloid-beta contrast agent and methods of use thereof - The invention provides ophthalmic formulations of Amyloid-β contrast agents. Also provided are methods of using such formulations in the diagnosis of Alzheimer's Disease or a predisposition thereto as well as methods for the prognosis of Alzheimer's Disease. | 02-12-2009 |
| 20090053712 | Methods of using LEDGF/p75 - The invention provides methods for diagnosing tumors in mammals using a reagent that bind to LEDGF/p75 or to a nucleic acid encoding LEDGF/p75. For example, the tumor may be located in the CNS, the prostate, the skin, the bone marrow, or the gut of the mammal. Also provided are methods for diagnosing brain tumors such as medulloblastomas, meningiomas, astrocytomas, glioblastomas multiforme, and ependymomas by examining LEDGF/p75 or a nucleic acid encoding LEDGF/p75 localization. The invention also involves methods for diagnosing cancers involving cancerous epithelial cells such as colon cancer. The instant invention also provides methods for isolating stem cells from a heterogeneous population of cells, as well as methods for identifying neuroepithelial stem cells, newly differentiated neurons, and astrocytes in a subject. Also provided are methods for inducing the differentiation of neuroepithelial stem cells into astrocytes or neurons and methods for screening candidate compounds that regulate the differentiation of neuroepithelial stem cells. | 02-26-2009 |
| 20110080559 | Ocular Imaging - A system for performing quasi-elastic light scattering and fluorescent ligand scanning on a subject's eye includes a light source configured to transmit light toward the subject's eye, a lens configured to focus light sent from the source and scattered by the subject's eye, a measurement reflector disposed to receive at least a portion of the focused light and configured to reflect a first portion of the received light, a camera configured and disposed to receive the first portion of the received light and configured to provide indicia of an image corresponding to the first portion of the received light, and a processor coupled to the camera and configured to analyze intensities of light in the image to determine a location of a reference point corresponding to an interface of a portion of the eye. | 04-07-2011 |
| 20130114042 | Ocular Imaging - A system for performing quasi-elastic light scattering and fluorescent ligand scanning on a subject's eye includes a light source configured to transmit light toward the subject's eye, a lens configured to focus light sent from the source and scattered by the subject's eye, a measurement reflector disposed to receive at least a portion of the focused light and configured to reflect a first portion of the received light, a camera configured and disposed to receive the first portion of the received light and configured to provide indicia of an image corresponding to the first portion of the received light, and a processor coupled to the camera and configured to analyze intensities of light in the image to determine a location of a reference point corresponding to an interface of a portion of the eye. | 05-09-2013 |
Lee Edwin Goldstein, Newton, MA US
Neil Goldstein, Belmont, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100309467 | Single-Shot Spectral Imager - A single-shot spectral imager or imaging system which acquires multiplexed spatial and spectral data in a single snapshot with high optical collection efficiency and with the speed limited only by the readout time of the detector circuitry. The imager uses dispersive optics together with spatial light modulators to encode a mathematical transform onto the acquired spatial-spectral data. A multitude of encoded images is recorded simultaneously on a focal plane array and subsequently decoded to produce a spectral/spatial hypercube. | 12-09-2010 |
| 20120206725 | External Cavity Laser Source - A tunable laser source that includes multiple gain elements and uses a spatial light modulator in an external cavity to produce spectrally tunable output is claimed. Several designs of the external cavity are described, targeting different performance characteristics and different manufacturing costs for the device. Compared to existing devices, the tunable laser source produces high output power, wide tuning range, fast tuning rate, and high spectral resolution. | 08-16-2012 |
Peter Goldstein, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20140278137 | DISTANCE MAPS USING MULTIPLE ALIGNMENT CONSENSUS CONSTRUCTION - Techniques for assembly of genetic maps including de novo assembly of distance maps using multiple alignment consensus construction. Multiple map alignment can be performed on a defined bundle of fragment maps corresponding to biomolecule fragments to determine consensus events and corresponding locations. Fragment maps in the bundle can be removed when there is no overhang from the consensus events. When the subset of fragment maps in the bundle is less than a predetermined threshold, one or more additional fragment maps can be added based on fragment signatures, a consensus alignment score, and a pairwise alignment score. Techniques for multiple alignment can include generating a graph with edges and vertices representing each pairwise relation. An ordered set of sets of events best representing a multiple alignment reflecting all pairwise alignments can be generated by repeatedly randomly removing edges and combining vertices to identify a min cut of the graph. | 09-18-2014 |
Peter H. Goldstein, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120122712 | Methods for Sequencing a Biomolecule by Detecting Relative Positions of Hybridized Probes - A sequencing method is presented in which a biomolecule is hybridized with a specially chosen pool of different probes of known sequence which can be electrically distinguished. The different probe types are tagged such that they can be distinguished from each other in a Hybridization Assisted Nanopore Sequencing (HANS) detection system, and their relative positions on the biomolecule can be determined as the biomolecule passes through a pore or channel. The methods eliminate, resolve, or greatly reduce ambiguities encountered in previous sequencing methods. | 05-17-2012 |
Peter Isaac Goldstein, Medford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20140321115 | LED-BASED DIRECT-VIEW LUMINAIRE WITH UNIFORM MIXING OF LIGHT OUTPUT - Methods and apparatus are provided for producing mixed light in a direct-view luminaire. The luminaire includes a plurality of light sources ( | 10-30-2014 |
| 20140340910 | LED-Based Luminaire Having a Mixing Optic - Disclosed is an LED-based luminaire ( | 11-20-2014 |
Scott Goldstein, Mashpee, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20140352164 | Tape Measure with Measurement Indicia Dial - A tape measure with a dial for storing a particular measurement value is provided. The present invention consists of a housing containing an extensible and retractable roll of measuring tape and a dial disposed on the outer face of the housing. The dial is used to store a measured value so that it can be remembered at a later time. Worksites are often noisy places filled with distractions, making it very easy to forget or misremember a measurement. When an individual forgets a measurement they are forced to either guess at the measurement value, potentially resulting in wasted materials and money, or re-measure the article, wasting valuable time. The present tape measure circumvents these problems by providing an easy and intuitive means for storing a numeric value while measuring so that it can be used for later without the user having to risk misremembering the value. | 12-04-2014 |
Seth Goldstein, Newburyport, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110185309 | GESTURE-BASED USER INTERFACE - The invention includes methods, systems, computer program products and means for providing an intuitive user interface for interacting with a game console that obviates the need for, or use of, a typical game controller. In one embodiment, the user interface comprises an analog-like mechanism for manipulating a menu and icon system. The menu system allows the user to highlight a menu option or icon using movement along one axis and to activate the menu option or icon via movement on a different axis. In one embodiment, highlighting is associated with a vertical motion and activation is associated with a horizontal motion. The vertical motion can be tied to the vertical movement of a particular appendage, e.g., the up and down movement of the user's right arm, and the horizontal motion can be tied to the horizontal movement of that or another appendage, e.g., movement of the right arm or hand across the body from right to left. | 07-28-2011 |
Stephan Goldstein, North Reading, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20130033299 | APPARATUS FOR INTERFACING CIRCUIT DOMAINS - An interface circuit for controlling a cross-domain signal link between a first circuit domain and a second circuit domain in a circuit may include first and second controllers, each of the first and second controllers including a first input coupled to a first voltage source of the first circuit domain and a second input coupled to a second voltage source of the second circuit domain. The interface circuit may further include a first switch controlled by an output of the first controller, the first switch including a first end coupled to the cross-domain signal link and a second end coupled to a first defined voltage state, and a second switch controlled by an output of the second controller, the second switch including a first end coupled to the cross-domain signal link and a second end coupled to a second defined voltage state, in which during a power-up of the circuit, if one of the first and second voltage sources is unavailable, at least one of the first and second controllers generates a control signal to engage at least one of the first and second switches and pull the cross-domain signal link to one of the first and second defined voltage states, while providing cross-domain protection against field-induced charge device model (FICDM) stress conditions at small drivers and receiver inputs connected to the signal interface link. | 02-07-2013 |
Susanne Beth Goldstein, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20150073824 | Systems and Methods for Evaluating Health Care Provider Referrals - In one embodiment, a method comprises accessing a physician-referral-network, which comprises a number of nodes and a number of edges connecting the nodes, each of the edges representing a single degree of separation between the nodes. Each node represents a physician, and each edge represents a patient-referral between two physicians corresponding to the connected nodes. One or more references indicating a patient-referral from a first physician to a second physician is received. The physician-referral-network is updated based on the received reference. One or more performance-scores from the second physicians may be received, each performance-score corresponding to a patient-referral. A referral-score is calculated for the first physician based on the performance-scores. The method further comprises determining if a referral-score for a first physician is below a threshold referral-score. | 03-12-2015 |
| 20150073833 | Systems and Methods for Evaluating Experience of a Health Care Provider - In one embodiment, a method comprises identifying one or more health-care-providers associated with one or more medical-specializations, wherein each medical-specialization is associated with a specialty class and at least one geographic area. A number of patient-diagnosis codes is received, each patient-diagnosis code corresponding to one of the health-care-providers and representing a patient-visit to the health-care-provider. The patient-diagnosis code includes at least one diagnosis within a condition-group for the patient visit, and a severity-factor for the diagnosis. The method further comprises determining all patient-diagnosis codes corresponding to the health-care-providers. A patient-volume is calculated for each health-care-provider, based on the patient-diagnosis codes and associated severity-factors. A variety-score is calculated for each health-care-provider based on the patient-diagnosis codes. An experience-score is calculated for each health-care-provider based on the patient-volume and variety-score. | 03-12-2015 |
| 20150073877 | Systems and Methods for Evaluating Performance of a Health Care Provider - In one embodiment, a method comprises receiving an indication of one or more care-episodes from a client device. Each care-episode may include an identifier for one or more physicians, a base-concept corresponding to a medical condition or medical treatment, one or more sub-concepts associated with the base-concept, and an indication of the resources used during the care-episode. The method comprises calculates one or more cost-factors for a base-concept for a particular physician based on the care-episodes associated with the base-concept. The method further comprises determining a specialty and geographic region of the particular physician. A peer group of physicians in the same specialty and geographic region is selected. A performance score is calculated based on the cost-factor for the physician compared to the cost-factors for the peer group of physicians. | 03-12-2015 |
| 20150073943 | Search Engine Systems for Matching Medical Providers and Patients - In one embodiment, a method comprises receiving a set of parameters for selecting a physician from an administrator of a matching-engine system. The matching-engine system stores the parameters in a data store of the matching-engine system. The matching-engine system receives from a user a search query with a location of the user and a user-specified symptom or treatment. The matching-engine system determines a base-concept of a medical diagnosis or medical procedure based on the search query. The matching-engine system may identify a set of physicians to be recommended to the user based on the parameters, and a performance-score and experience-score associated with the base-concept for each physician. The matching-engine system may send a search-results page to the user listing the recommended physicians. | 03-12-2015 |