Gilkeson
Gary Gilkeson, Charleston, SC US
Patent application number | Description | Published |
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20080221011 | Targeting complement factor H for treatment of diseases - The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion. | 09-11-2008 |
20110015127 | TARGETING COMPLEMENT FACTOR H FOR TREATMENT OF DISEASES - The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion. | 01-20-2011 |
20140073572 | TARGETING COMPLEMENT FACTOR H FOR TREATMENT OF DISEASES - The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion. | 03-13-2014 |
Gary Steven Gilkeson, Charleston, SC US
Patent application number | Description | Published |
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20140154307 | INHIBITION OF FACTOR B, THE ALTERNATIVE COMPLEMENT PATHWAY AND METHODS RELATED THERETO - Disclosed are novel inhibitors of the alternative complement pathway and particularly, novel anti-factor B antibodies. Also disclosed is the use of such inhibitors to reduce or prevent airway hyperresponsiveness and/or airway inflammation by selectively inhibiting the alternative complement pathway, thereby treating diseases in which such conditions play a role. Also disclosed is the use of such inhibitors to reduce or prevent other diseases and conditions, including ischemia-reperfusion injury, by inhibition of the alternative complement pathway. | 06-05-2014 |
Robert Gilkeson, Cleveland Hts., OH US
Patent application number | Description | Published |
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20090279761 | Systems and Methods for Generating Images for Identifying Diseases - Systems and methods for generating images for identifying diseases are provided. In one embodiment, a method comprises receiving a first digital radiography (DR) image of at least a portion of a body of a patient, receiving a second DR image of the at least a portion of a body of a patient, the first DR image being captured at a different energy level than the second DR image, and determining common control point locations for both the first and second DR images. The method further comprises generating an optimized DR image by moving portions of a selected one of the first and second DR images with its associated control points to locations that correspond to similar portions of the other of the first and second DR images, applying deformable transformation to one of the first and second DR images and performing a log subtraction on the first and second DR image to generate a dual-energy digital radiography (DEDR) image. | 11-12-2009 |
20120039519 | SYSTEMS AND METHODS FOR GENERATING IMAGES FOR IDENTIFYING DISEASES - A method is provided that comprises receiving a first digital radiography (DR) image of at least a portion of a body of a patient, receiving a second DR image of the at least a portion of a body of a patient, the first DR image being captured at a different energy level than the second DR image, and determining common control point locations for both the first and second DR images. The method further comprises generating an optimized DR image by moving portions of a selected one of the first and second DR images with its associated control points to locations that correspond to similar portions of the other of the first and second DR images, applying deformable transformation to one of the first and second DR images and performing a log subtraction on the first and second DR image to generate a dual-energy digital radiography (DEDR) image. | 02-16-2012 |