Patent application number | Description | Published |
20090181027 | Anti-IL-12/23p40 Antibodies, Epitopes, Formulations, Compositions, Methods and Uses - An anti-IL-12/23p40 antibody that binds to a portion of the IL-12 or IL-23 protein corresponding to the p40 subunit of IL-12 or IL-23, including compositions, formulations, and methods of administration have applications in diagnostic and/or therapeutic uses and devices. | 07-16-2009 |
20100111959 | ENGINEERED ANTI-IL-13 ANTIBODIES, COMPOSITIONS, METHODS AND USES - The present invention relates to engineered antibodies immunospecific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications. | 05-06-2010 |
20120045438 | ENGINEERED ANTI-IL-13 ANTIBODIES, COMPOSITIONS, METHODS AND USES - The present invention relates to engineered antibodies immuno specific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications. | 02-23-2012 |
20130064760 | Method for Treating Crohn's Disease By Administering An Anti-IL-12 Antibody - Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of antibody or portions for treating and/or diagnosing IL-12 related conditions, diseases, and disorders, such as Crohn's disease. | 03-14-2013 |
20130129617 | Method for Treating Psoriatic Arthritis By Administering An Anti-IL-12 Antibody - An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in treating IL-12-related disorders, such as psoriatic arthritis. | 05-23-2013 |
Patent application number | Description | Published |
20140141013 | ANTI-IL-6 ANTIBODIES, COMPOSITIONS, METHODS AND USES - The present invention relates to at least one novel chimeric, humanized or CDR-grafted anti-IL-6 antibodies derived from the murine CLB-8 antibody, including isolated nucleic acids that encode at least one such anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices. | 05-22-2014 |
20140161816 | ANTI- TNF ANTIBODIES, COMPOSITIONS, METHODS AND USES - The present invention relates to anti-TNF antibodies comprising all of the heavy chain variable CDR regions of SEQ ID NOS: 1, 2 and 3 and/or all of the light chain variable CDR regions of SEQ ID NOS:4, 5 and 6, specific for at least one human tumor necrosis factor alpha (TNF) protein or fragment thereof, as well as nucleic acids encoding such anti-TNF antibodies, complementary nucleic acids, vectors, host cells, production methods and therapeutic methods. | 06-12-2014 |
20140178295 | Method for Treating Psoriasis By Administering An Anti-IL-12 Antibody - Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of antibody or portions for treating and/or diagnosing IL-12 related conditions, diseases, and disorders, such as psoriasis. | 06-26-2014 |
20140255388 | TOLL LIKE RECEPTOR 3 ANTAGONISTS, METHODS AND USES - Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments, and methods of making and using the foregoing are disclosed. | 09-11-2014 |
20150030608 | Method of Treating Crohn's Disease By Administering An Anti-IL-12 Antibody - An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 01-29-2015 |
Patent application number | Description | Published |
20080286289 | Use of B Cell Expansion Agents in Generating Antibodies - A method for efficiently generating antibodies immunizes an animal with a target antigen and a B cell expansion agent, such as an anti-CD40 agonist. The antibodies generated from this method are useful as therapeutic agents, diagnostic agents or research reagents in a variety of diseases and conditions. | 11-20-2008 |
20090162371 | Anti-IL-23 Antibodies, Compositions, Methods and Uses - An anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 06-25-2009 |
20100322863 | Methods and Uses of Anti-IL-23 Antibodies - An anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 12-23-2010 |
20110200613 | Use of B Cell Expansion Agents in Generating Antibodies - A method for efficiently generating antibodies immunizes an animal with a target antigen and a B cell expansion agent, such as an anti-CD40 agonist. The antibodies generated from this method are useful as therapeutic agents, diagnostic agents or research reagents in a variety of diseases and conditions. | 08-18-2011 |
20110319292 | METHODS FOR GENERATING ANTI-IL-23 ANTIBODIES, COMPOSITIONS, METHODS AND USES - A protein variant of IL-23p19 that has conserved residues in positions 93-102, 93-110, and/or 127-137 of SEQ ID NO:1, can be used to generate anti-IL-23p19 antibodies. | 12-29-2011 |
20120189643 | Toll Like Receptor 3 Antagonists, Methods and Uses - Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments thereof, and methods of making and using the foregoing are disclosed. | 07-26-2012 |
20120308573 | Anti-IL-23 Antibodies, Compositions, Methods and Uses - An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 12-06-2012 |
Patent application number | Description | Published |
20140046031 | Anti-IL-23 Antibodies, Compositions, Methods and Uses - An anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 02-13-2014 |
20140128576 | Anti-IL-23 Antibodies, Compositions, Methods and Uses - An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 05-08-2014 |