Patent application number | Description | Published |
20080269256 | PYRIDINE-2-CARBOXYAMIDE DERIVATIVES - The invention relates to compounds of formula I: | 10-30-2008 |
20090018171 | IMIDAZOLE DERIVATIVES - The present invention relates to imidazole derivatives of formula I | 01-15-2009 |
20090029977 | DUAL MODULATORS OF 5HT2A AND D3 RECEPTORS - The present invention relates to compounds of the formula (I) | 01-29-2009 |
20090042943 | BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS - The present invention relates to compounds of formula (I) | 02-12-2009 |
20090054490 | METHODS FOR THE TREATMENT OF GERD WITH MGLUR5 ANTAGONISTS - The present invention relates to methods for the treatment, prevention and/or delay of progression of gastro-esophageal reflux disease (GERD) by administering compounds that act as antagonists of metabotropic glutamate type-5 receptors (mGluR5 receptor antagonists), for example compounds of formula (I) | 02-26-2009 |
20100048569 | DIAZOLE DERIVATIVES - The present invention relates to diazole derivatives of the general formula | 02-25-2010 |
20100075979 | PYRIDINYLPIPERAZIN DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS - The present invention provides compounds of provides formula I, having affinity and selectivity for the dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use for the therapeutic and/or prophylactic treatment of cognitive disorders. | 03-25-2010 |
20100075981 | ISOXAZOLO[4,5]PYRIDIN-3-YL-PIPERAZIN DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS - The present invention provides compounds of formula I, having affinity and selectivity for the dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use for the therapeutic and/or prophylactic treatment of cognitive disorders. | 03-25-2010 |
20100075983 | D3 AND 5-HT2A RECEPTOR MODULATORS - The present invention provides compounds of the general formula (I) | 03-25-2010 |
20100075985 | BENZO[D]ISOXAZOL-3-YL-PIPERAZIN DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS - The present invention provides compounds of the general formula (I), having affinity and selectivity for the dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use for the therapeutic and/or prophylactic treatment of cognitive disorders. | 03-25-2010 |
20100227887 | PYRIDINE-2-YL CARBOXYLIC ACID AMIDES - The present invention relates to pyridine-2-yl-carboxylic acid amides which act as metabotropic glutamate receptor antagonists. In particular, the present invention relates to pyridine-2-yl-carboxylic acid amides of formula I | 09-09-2010 |
20110015202 | IMIDAZOLES - The present invention relates to imidazole derivatives of the general formula | 01-20-2011 |
20110098313 | POSITIVE ALLOSTERIC MODULATORS (PAM) - The present invention relates to phenylethynyl compounds of formula I | 04-28-2011 |
20110152257 | ETHYNYL COMPOUNDS USEFUL FOR TREATMENT OF CNS DISORDERS - The present invention relates to ethynyl compounds of formula | 06-23-2011 |
20110251169 | Arylethynyl derivatives - The present invention relates to ethynyl compounds of formula I | 10-13-2011 |
20120004208 | BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS - The present invention relates to compounds of the general formula | 01-05-2012 |
20120040972 | DUAL MODULATORS OF 5HT2A AND D3 RECEPTORS - The present invention relates to compounds of the formula (I) | 02-16-2012 |
20120270852 | PHENYL OR PYRIDINYL-ETHYNYL DERIVATIVES - The present invention relates to ethynyl derivatives of formula I | 10-25-2012 |
20120277213 | ETHYNYL COMPOUNDS - The present invention relates to ethynyl derivatives of formula I | 11-01-2012 |
20120277243 | PYRAZOLIDIN-3-ONE DERIVATIVES - The present invention relates to ethynyl derivatives of formula I | 11-01-2012 |
20130090332 | ETHYNYL DERIVATIVES - The present invention relates to ethynyl derivatives of formula I | 04-11-2013 |
20130090347 | ETHYNYL DERIVATIVES - The present invention relates to ethynyl derivatives of formula I | 04-11-2013 |
20130123254 | PHARMACEUTICALLY ACCEPTABLE MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND THEIR METHODS OF IDENTIFICATION - The present invention relates to mGluR5 positive allosteric modulators (PAM) and methods for identifying pharmaceutically acceptable compounds with high tolerability and safety, which method comprises the use of at least one non-competitive mGluR5 allosteric modulator which has a shift factor measured at 10 uM glutamate concentration below 3.0, | 05-16-2013 |
20130131056 | POSITIVE ALLOSTERIC MODULATORS (PAM) - The present invention relates to phenylethynyl compounds of formula I | 05-23-2013 |
20130165432 | Dual Modulators of 5HT2A and D3 Receptors - The present invention relates to compounds of the formula (I) | 06-27-2013 |
20130178456 | ARYLETHYNYL DERIVATIVES - The present invention relates to ethynyl compounds of formula I | 07-11-2013 |
20130274464 | Arylethynyl Derivatives - The present invention relates to ethynyl compounds of formula I | 10-17-2013 |
20140073638 | ETHYNYL COMPOUNDS USEFUL FOR TREATMENT OF CNS DISORDER - The present invention relates to ethynyl compounds of formula | 03-13-2014 |
20140155602 | Arlethynyl Derivatives - The present invention relates to ethynyl compounds of formula I-C1 | 06-05-2014 |
20140350051 | Dual Modulators Of 5HT2A and D3 Receptors - The present invention relates to compounds of the formula (I) | 11-27-2014 |