Fridman
Alexander E. Fridman, Moscow RU
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20130002486 | L1/L2 GPS RECEIVER WITH PROGRAMMABLE LOGIC - A Global Positioning System (GPS) commercial receiver includes programmable logic that utilizes P-code modulated L1 and L2 GPS signals to derive estimates of in-phase and quadrature-phase components of both L1 and L2 signals, a programmable processor that calculates pseudoranges and pseudo-Doppler phases, and derives navigation solutions. A resulting complex accumulated L2 signal comprises near-ML estimates of desired L2 amplitude and pseudo- Doppler phase. | 01-03-2013 |
Amir Fridman, Tel Aviv IL
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20110040918 | Host for Use with Dual Interface Card with Backward and Forward Compatibility - Techniques are presented that allow a memory card operable according to two protocols (such as a legacy protocol and newer protocol), and having a corresponding dual interface, to be used with hosts that support the new protocol as well as having backward compatibility with legacy hosts, while preventing the use of legacy cards with hosts that support the new protocol but do not support the legacy protocol. The card that supports the new protocol has a similar form factor to the legacy card, includes an indentation. A host that supports the new, but not the legacy, type card includes a mechanical structure within the attachment slot that, based on the card indentation, can distinguish the card types and prevent the non-supported card from being attached. | 02-17-2011 |
20110072185 | MULTI-PROTOCOL STORAGE DEVICE BRIDGE - A bridge includes a host interface via which data/commands are received from and transferred to a host, and a storage device interface via which data/commands are received from and transferred to a storage device. The bridge also includes one SDPC, a controller and a switching system that is configurable by the controller to connect the protocol converter to the host interface and the storage device interface if the storage device protocol used by the host device differs from the storage device protocol used by the storage device, and to connect the host device interface to the storage device interface, not via the bi-directional protocol converter, if the two storage device protocols are the same. The bridge may include two SDPCs, each for converting a different protocol to the host protocol and vice versa, with the switching system being configurable to switch between the two SDPCs. The bridge may omit the SDPC altogether, with the switching system being configurable to switch between connecting (1) the host device interface to the storage device interface, and (2) bypassing the storage device interface. | 03-24-2011 |
20110189866 | Dual Interface Card with Backward and Forward Compatibility - Techniques are presented that allow a memory card operable according to two protocols (such as a legacy protocol and newer protocol), and having a corresponding dual interface, to be used with hosts that support the new protocol as well as having backward compatibility with legacy hosts, while preventing the use of legacy cards with hosts that support the new protocol but do not support the legacy protocol. The card that supports the new protocol has a similar form factor to the legacy card, includes an indentation. A host that supports the new, but not the legacy, type card includes a mechanical structure within the attachment slot that, based on the card indentation, can distinguish the card types and prevent the non-supported card from being attached. | 08-04-2011 |
20130012049 | DUAL INTERFACE CARD WITH BACKWARD AND FORWARD COMPATIBILITY - A memory card includes a first set of contacts and a second set of contacts. A first edge of the memory card includes an indentation. Insertion of the memory card into a first slot of a host device engages the first set of contacts. The indentation is configured to accept a pivoting lever arm located in the first slot when the memory card is inserted into the first slot. | 01-10-2013 |
20130013836 | HOST FOR USE WITH DUAL INTERFACE CARD WITH BACKWARD AND FORWARD COMPATIBILITY - A host device includes a slot configured to receive a first type of memory card having an indentation and a mechanical structure. The mechanical structure includes a pivot structure and a lever arm. The lever arm is configured to pivot on the pivot structure and a portion of the lever arm is configured to at least partially fit into the indentation to distinguish the first type of memory card from a second type of memory card. | 01-10-2013 |
Anatoly Fridman, Newmarket CA
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20150109015 | SYSTEM-LEVEL TESTING OF NON-SINGULATED INTEGRATED CIRCUIT DIE ON A WAFER - Structures and methods for system-level testing of integrated circuit dies at wafer sort is disclosed. This concept combines a system-level test (which is traditionally a “socketed” test performed on a packaged IC in a test socket) with the ability to contact an integrated circuit die on a wafer using a probe card. The die on the wafer becomes part of the system-level environment in order to test the integrated circuit die in the system-level environment prior to packaging, and may be used to better identify known good die. | 04-23-2015 |
Andrei L. Fridman, Eidswoll Verk NO
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20140293062 | Hyperspectral Camera and Method for Acquiring Hyperspectral Data - A hyperspectral camera includes light mixing chambers ( | 10-02-2014 |
Catherine Fridman, Paris FR
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20120100133 | USE OF ANTI-CD20 ANTIBODY FOR TREATING PRIMARY INTRAOCULAR LYMPHOMA - An embodiment relates to a monoclonal antibody directed against the CD20 antgen, in which the variable region of each of the light chains is coded by murine nucleic acid sequence SEQ ID NO:1, the variable region of each of the heavy chains is coded by murine nucleic acid sequence SEQ ID NO: 2, and the constant regions of the light chains and of the heavy chains originate from a non-murine species, said antibody being used for treating primary intraocular lymphoma. | 04-26-2012 |
Daniel Pallos Fridman, Araxa BR
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20160122848 | PROCESSES FOR PRODUCING LOW NITROGEN METALLIC CHROMIUM AND CHROMIUM-CONTAINING ALLOYS AND THE RESULTING PRODUCTS - Processes for producing low-nitrogen metallic chromium or chromium-containing alloys, which prevent the nitrogen in the surrounding atmosphere from being carried into the melt and being absorbed by the metallic chromium or chromium-containing alloy during the metallothermic reaction, include vacuum-degassing a thermite mixture comprising metal compounds and metallic reducing powders contained within a vacuum vessel, igniting the thermite mixture to effect reduction of the metal compounds within the vessel under reduced pressure i.e., below 1 bar, and conducting the entire reduction reaction in said vessel under reduced pressure, including solidification and cooling, to produce a final product with a nitrogen content below 10 ppm. The final products obtained, in addition to low-nitrogen metallic chromium in combination with other elements, can be used as raw materials in the manufacture of superalloys, stainless steel and other specialty steels whose final content of nitrogen is below 10 ppm. | 05-05-2016 |
David Fridman, Hod Hasharon IL
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20160055490 | DEVICE, SYSTEM, AND METHOD OF PROTECTING BRAND NAMES AND DOMAIN NAMES - A computerized method of protecting a brand name of a brand owner, includes: (a) crawling a global communication network to identify and collect data about web-sites that possibly abuse the brand name; (b) for each web-site that possibly abuses the brand name, analyzing whether or not the web-site abuses the brand name by analyzing at least one of: (i) content of the web-site; and (ii) data about an owner of the web-site. The method further includes: for each web-site that possibly abuses the brand name, (A) generating an investment score indicating an estimated level of investment that was invested in development of the web-site; and (B) generating a damage score indicating a level of damage that the web-site is estimated to produce to the brand name. | 02-25-2016 |
Eran Fridman, Zofit IL
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20130232216 | METHOD FOR EFFICIENT USE OF CONTENT STORED IN A CACHE MEMORY OF A MOBILE DEVICE - A method for cache management of a mobile device communicatively connected to a network component via a network is provided. The method comprises receiving by the network component a request from the mobile device for a data item, the request accompanied by a unique identifier associated thereto, the data item residing in the cache; fetching the data item from at least a server communicatively connected to the network component; generating a unique identifier respective of the fetched data item; and comparing the generated unique identifier and the received unique identifier to determine whether the data item in the cache is the same as the data item fetched from the at least a server. | 09-05-2013 |
20140237109 | TECHNIQUES FOR DETERMINING A MOBILE APPLICATION DOWNLOAD ATTRIBUTION - A proxy server and a method for determining a mobile application download attribution are provided. The method includes identifying an application downloaded from an application repository to a mobile device; analyzing previously logged requests sent from the mobile device to identify a most recent request directed to the application repository from the mobile device; analyzing the identified most recent request to detect a source that causes the application download and at least one identifier of the application; determining the download attribution respective of the source that causes the application download; and generating an application metadata respective of the download attribution and the application identifiers. This is subject to a user's privacy, opt-in, or opt-out settings. | 08-21-2014 |
Eran Fridman, Neve Yarak IL
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20130262675 | PROXY AND METHOD FOR DETERMINATION OF A UNIQUE USER IDENTIFICATION FOR A PLURALITY OF APPLICATIONS ACCESSING THE WEB FROM A MOBILE DEVICE - A proxy and a method for providing a unique user identification (UUID) to a mobile device executing a plurality of mobile applications. The method includes receiving a request to access an Internet resource by a mobile application of the plurality of mobile applications; generating a unique user identification (UUID) to uniquely identify the mobile device, thereby the UUID enables the at least one Internet resource to uniquely identify the mobile device regardless of which of the plurality of mobile applications made a request to the Internet resource; associating to the request the UUID; and forwarding the request with the UUID to the Internet resource. | 10-03-2013 |
20140214921 | SYSTEM AND METHOD FOR IDENTIFICATION OF AN APPLICATION EXECUTED ON A MOBILE DEVICE - A method for uniquely identifying an application executed on a mobile device is provided. The method comprises trapping a request to execute an application by the mobile device, wherein the request is initiated by the application and directed to an Internet resource associated with the application; identifying a source of the request; generating metadata respective of the application initiated the request; and sending the metadata to the a proxy server communicatively connected to the mobile device, wherein the proxy server is configured to uniquely identify a name and a type of the application by matching information in the metadata to an app-index. This is subject to a user's privacy, opt-in, or opt-out settings. | 07-31-2014 |
Gil Fridman, Hoshaya IL
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20150097846 | External Validation of Graphics Pipelines - Data may be streamed out of a graphics pipeline during run time without preprogramming the stream out. A command stream may be captured, draw commands monitored, and shader output definitions may be parsed to determine how to stream out shader data, for example for debugging. | 04-09-2015 |
Herve Fridman, Paris FR
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20110195923 | Methods for Predicting the Response to Anti-Cancer Treatment with an Agonist of TLR7 or an Agonist of TLR8 - The present invention relates to methods for predicting the response to treatment with an agonist of TLR7, or an agonist of TLR8 or an anti-cancer agent for treating cancer, in particular non-small cell lung cancer comprising the step of detecting the expression of TLR7 or TLR8 in cancer cells of said patient. | 08-11-2011 |
20130203614 | METHODS FOR PREDICTING THE SURVIVAL TIME OF A PATIENT SUFFERING FROM A SOLID CANCER - The present invention provides methods and kits for the prognosis of survival time of a patient suffering from a cancerous tumor. The method involves quantitating the density of Th17 cells at the center of the tumor and at the invasive margin of the tumor, where low density values at each location indicate a favourable prognosis, high values at each location indicate an unfavourable prognosis, and heterogeneous values at the two locations (one high, one low) indicate an intermediate prognosis. | 08-08-2013 |
20130331291 | METHOD FOR PREDICTING THE OUTCOME OF COLON CANCER BY ANALYSING MIRNA EXPRESSION - The present invention relates to a method for predicting the outcome of a cancer. More particularly, the present invention relates to a method for predicting the outcome of a cancer in a patient comprising a step consisting of determining the expression level of a miRNA cluster in a sample obtained from said patient, wherein said miRNA cluster comprises: -miR.609 or, -miR.518c or, -miR.520f or, -miR.220a or, -miR.362 or, -miR.29a or, -miR.660 or, -miR.603 or, -miR.558 or, -miR519b or, -miR.494 or, -miR.130a or, -miR.639. | 12-12-2013 |
20140018255 | METHODS FOR PREDICTING THE OUTCOME OF A CANCER IN A PATIENT BY ANALYSING GENE EXPRESSION - The present invention relates to a method for predicting the outcome of a cancer in a patient by analysing gene expression in a sample obtained from said patient. More particularly the present invention relates to a method for predicting the outcome of a cancer comprising a step consisting of determining the expression level of a gene cluster consisting of at least 3 genes in a sample obtained from said patient. | 01-16-2014 |
20140288018 | METHODS FOR PREDICTING THE RESPONSE TO ANTI-CANCER TREATMENT WITH AN AGONIST OF TLR7 OR AN AGONIST OF TLR8 - The present invention relates to methods for predicting the response to treatment with an agonist of TLR7, or an agonist of TLR8 or an anti-cancer agent for treating cancer, in particular non-small cell lung cancer comprising the step of detecting the expression of TLR7 or TLR8 in cancer cells of said patient. | 09-25-2014 |
20140363472 | METHODS FOR PREDICTING THE SURVIVAL TIME OF A PATIENT SUFFERING FROM A SOLID CANCER BASED ON DENSITY OF B CELLS - The present invention relates to a method for predicting the survival time of a patient suffering from a solid cancer comprising the steps consisting of i) determining the density of B cells at the invasive margin of the tumor (im) in a tumor tissue sample obtained from said patient, ii) comparing said density with a predetermined reference value and iii) providing a good prognosis when the density of B cells at the invasive margin of the tumor is higher than the predetermined reference value and a poor prognosis when the density of B cells at the invasive margin of the tumor is lower than the predetermined reference value. | 12-11-2014 |
20150225799 | METHODS FOR PREDICTING THE OUTCOME OF A CANCER IN A PATIENT BY ANALYSING GENE EXPRESSION - The present invention relates to a method for predicting the outcome of a cancer in a patient by analysing gene expression in a sample obtained from said patient. More particularly the present invention relates to a method for predicting the outcome of a cancer comprising a step consisting of determining the expression level of a gene cluster consisting of at least 3 genes in a sample obtained from said patient. | 08-13-2015 |
20150369811 | METHODS FOR PREDICTING THE SURVIVAL TIME OF A PATIENT SUFFERING FROM A SOLID CANCER - The present invention provides methods and kits for the prognosis of survival time of a patient suffering from a cancerous tumor. The method involves quantitating the density of Th17 cells at the center of the tumor and at the invasive margin of the tumor, where low density values at each location indicate a favourable prognosis, high values at each location indicate an unfavourable prognosis, and heterogeneous values at the two locations (one high, one low) indicate an intermediate prognosis. | 12-24-2015 |
Katia Fridman, Ashdod IL
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20150263386 | LITHIUM ION SECONDARY BATTERY COMPRISING A SILICON ANODE - A lithium ion secondary battery comprising: (i) a cathode comprising a cathode active material that can reversibly oclude and release lithium ions wherein the upper cut-off voltage for the cathode during charging against Li/Li | 09-17-2015 |
Merav Fridman, Ra-Anana IL
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20160095061 | REDUCED POWER CONSUMPTION USING COORDINATED BEACON SKIPPING - In order to reduce the power consumption associated with waking and receiving beacons, a current listening device in a group of electronic devices wakes and scans for a beacon from another electronic device (such as an access point) using a wireless-local-area-network (WLAN) communication protocol (such as Wi-Fi®). Then, the current listening device transmits information associated with the beacon to the group of electronic devices using a second communication protocol (such as Bluetooth® Low Energy), which is different than the WLAN communication protocol and has a lower power consumption. Moreover, the current listening device receives, using the second communication protocol, a sequence of responses from the group of electronic devices indicating that the information was received, wherein the responses from different electronic devices are received at different times. For example, the responses may be received in a predefined order and/or in round-robin fashion for the group of electronic devices. | 03-31-2016 |
Micha Fridman, Kiryat Bialik IL
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20160115525 | DETECTION OF HYDROXYMETHYLCYTOSINE BASES - Methodologies for labeling the epigenetic modification 5-hydroxymethyl-cytosine (5hmC) along a DNA molecule, and for imaging this epigenetic modification along a DNA molecule are disclosed. Related compositions and reagents, and methods of preparing same are also disclosed. | 04-28-2016 |
Micha Fridman, Qiryat Bialik IL
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20130045933 | ALOE-EMODIN DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF CANCER - The present invention relates to anthracycline derivatives that are based on an Aloe-emodin (AE) backbone attached to a glycoside (an amino sugar or amino carba-sugar). These derivatives are useful as chemotherapeutic agents. Advantageously, these derivatives are potent cytotoxic agents against a variety of anthracycline-resistant tumors. In addition, they may have reduced cardiotoxicity. As such, the novel compounds of the invention offer an advantage over currently available drugs. The present invention further relates to methods for preparing the novel Aloe-Emodin Glycoside (AEG) based derivatives, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially as chemotherapeutic agents for prevention and treatment of cancers. | 02-21-2013 |
Moti Fridman, Rehovot IL
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20130010295 | SYSTEM AND METHOD FOR POLARIZATION MEASUREMENT - A system and method are presented for use in measuring polarization of an optical beam. The system is configured and operable for determining polarization profile along a cross section of the input optical beam, and comprises an optical system and a pixel matrix. The optical system comprises a polarization beam splitting assembly configured and operable for splitting said input optical beam into a predetermined number of beam components with a predetermined polarization relation between them, the polarization beam splitting assembly comprising a first polarization beam splitter in an optical path of the input optical beam splitting said input optical beam into a first plurality of beam components with a certain polarization relation between them and a birefringent element in an optical path of said first plurality of the beam components for splitting each of them into a pair of beams having ordinary and extraordinary polarizations, thereby producing said predetermined number of output beam components. The pixel matrix is located in substantially non intersecting optical paths of said output beam components and generates a corresponding number of output data pieces indicative of intensity distribution within said output beam components, respectively, data contained in said data pieces being indicative of the polarization profile along the cross section of the input optical beam. | 01-10-2013 |
Natalie Fridman, Petach Tikva IL
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20090265299 | COMPUTING SOLUTIONS TO PROBLEMS USING DYNAMIC ASSOCIATION BETWEEN ABSTRACT GRAPHS - A device, system, and method for solving a plurality of sub-problems representing a main problem pertaining to an environment. An abstract graph corresponding to each of the sub-problems may be constructed in a computing system for each of the sub-problems. At least a first abstract graph of the abstract graphs may be resolved, for example, by decomposing one or more nodes of the first abstract graph. At least one of the one or more nodes of the first abstract graph may be associated with one or more nodes of others of the abstract graphs. At least one of the abstract graphs may be resolved using information obtained by the association. Other embodiments are described and claimed. | 10-22-2009 |
Ofer Fridman, Lotem IL
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20100030057 | IMAGING CATHETER - A catheter for conveying flowables in or out of the body, be they gases or liquids. The catheter has a triangular lumen and optional auxiliary structures. One optional element is guide engaging for employing a guide for placing the catheter. Another element is a secondary lumen disposed within the wall of the tube. The camera and lighting devices at the tip of the catheter are mounted on a partially flexible PCB and packaged in the tube permitting all elements to point substantially forwards. | 02-04-2010 |
20150065994 | POSTERIOR BREAST MASSAGE UNIT - A method of milk extraction system may include massaging a posterior of a breast. Massaging and collecting milk may optionally be performed simultaneously. A posterior massager may also be used and/or mounted separately from a collection unit. In some embodiments the massager may be used to improve milk collection and/or alleviate breast ailments for example engorgement, plugged ducts, and/or mastitis. A collection flange may include an air inlet manifold, to mix air and milk. Optionally as air is drawn along a tube by a vacuum, milk may be entrained in the airstream and brought towards a collection vessel. The system may include automated tracking of milk production and/or consumption. | 03-05-2015 |
Ofer Fridman, Haifa IL
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20140083402 | CLAY-PIGEON-LIKE PROJECTILE FOR CROWD CONTROL - A crowd control projectile includes a payload carrier, an incapacitating agent inside the payload carrier, and an activating mechanism for activating the incapacitating agent. The activating mechanism includes a sensor and a timer. The timer delays the activation until a predetermined delay after the sensor senses that the projectile has been launched. Alternatively, the activating mechanism includes a receiver for receiving an activation signal after the projectile has been launched. Preferably, the projectile has the shape of a clay pigeon. A launcher of such a projectile includes a communication mechanism for transmitting a timing signal or an activation signal to the projectile and an arm for launching the projectile by direct contact. To control a crowd, the projectile is launched over the crowd by direct contact with a solid arm and the activating mechanism is used to activate the incapacitating agent when the projectile is above the crowd. | 03-27-2014 |
Ofer Fridman, Bikat Beit Hakerem IL
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20100087804 | SYSTEM AND METHOD FOR TREATING TISSUE - A method and system for tissue treatment, wherein the method includes transmitting energy onto tissue to be treated, and maintaining a required distance, during the tissue treatment, between a hand piece and the tissue. The method may further include applying a soldering agent for facilitating tissue soldering, used as adhesive to various types of protein in human tissue, wherein the transmitting energy activates the soldering agent applied on the tissue. | 04-08-2010 |
Ofer Fridman, D.n. Bikat Beit Hakerem IL
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20100280545 | SYSTEM AND METHOD FOR BONDING LIVING TISSUE - A system for bonding living tissue including first tissue displacer functionality operative initially to cause displacement of edges of tissue into a mutual touching relationship along a seam prior to bonding thereof and second tissue displacer functionality operative following operation of the first tissue displacer functionality to cause displacement of the edges into a mutual non-touching relationship wherein the edges are in mutual propinquity. | 11-04-2010 |
Sharon Fridman, London GB
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20100057767 | SYSTEM AND METHOD FOR DYNAMICALLY CREATING AND/OR UPDATING SUBSCRIBER COMMUNICATIONS LISTS - A system and method are disclosed herein for dynamically updating a first subscriber communications list or creating a new subscriber communications list based on awareness information data, the method comprising creating a rule for defining a second subscriber communications list, the second subscriber communications list being an updated first subscriber communications list or being a created new subscriber communications list; storing the rule; retrieving and pre-processing existing data; retrieving and pre-processing the awareness information data; and storing the second subscriber communications list. | 03-04-2010 |
20110022444 | SYSTEM AND METHOD FOR ASSESSING MOBILE APPLICATION VALUE - A method and system for assessing a value of a first application with respect to a use of a mobile communication device in communication with a second communication device are presented. The method entails assigning a set of proximity values that relate the use of the application to the communication between the mobile communication device and the second communication device, and determining an impact and a value based on the proximity values. The proximity values may include a relationship proximity value, a time proximity value, a geographical proximity value, an action proximity value, and one or more user-defined proximity values. The determined value may be expressed as a monetary value. | 01-27-2011 |
20120157137 | SYSTEM AND METHOD FOR ASSESSING MOBILE APPLICATION VALUE - A method and system for assessing a value of a first application with respect to a use of a mobile communication device in communication with a second communication device are presented. The method entails assigning a set of proximity values that relate the use of the application to the communication between the mobile communication device and the second communication device, and determining an impact and a value based on the proximity values. The proximity values may include a relationship proximity value, a time proximity value, a geographical proximity value, an action proximity value, and one or more user-defined proximity values. The determined value may be expressed as a monetary value. | 06-21-2012 |
Tzvika Fridman, Kiryat Ono IL
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20100028134 | QUIET FAN INCORPORATING ACTIVE NOISE CONTROL (ANC) - An active noise control (ANC) system may be implemented to both sides of a fan, such that both directions of the noise emitting are treated to reduce the overall noise. The impact on airflow is minimal, and the technique is very effective in a broad range of low frequencies. Passive sound-absorbing materials may be included for attenuation of high frequencies. The resulting quiet fan produces a low level of noise compared to any other device based on fan, which produces the same capacity of airflow. The quiet fan may be incorporated in any mechanical system which requires airflow induction such as: computers, air conditioners, machines, and more. | 02-04-2010 |
Victor Fridman, Calgary CA
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20130192840 | MULTILATERAL LOCATION AND ORIENTATION ASSEMBLY - A location and orientation assembly suitable for use in a multi-lateral wellbore may include a coupling portion, an upper muleshoe, a muleshoe spacer and a bottom muleshoe. The bottom muleshoe may connect to the coupling portion through a threaded connection. A method for locating and orienting in a multi-lateral wellbore includes providing a locating and orientation assembly. In the orientation assembly a coupling portion is provided and an upper muleshoe is inserted into the coupling portion. A muleshoe spacer is inserted into the coupling portion so as to matingly contact the upper muleshoe portion. Part of a bottom muleshoe is inserted into the coupling portion so as to matingly contact the muleshoe spacer. The coupling portion is jointed to the bottom muleshoe by a threaded connection. | 08-01-2013 |
Wolf-Herman Fridman, Paris FR
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20090215053 | Vitro Method for the Prognosis of Progression of a Cancer and of the Outcome in a Patient and Means for Performing Said Method - The present invention relates to the prognosis of the outcome of a cancer in a patient, which prognosis is based on the quantification of one or several biological markers that are indicative of the presence of, or alternatively the level of, the adaptive immune response of said patient against said cancer. | 08-27-2009 |
20110178069 | INHIBITORS OF INTERLEUKIN-1 BETA CONVERTING ENZYME - The present invention relates to novel classes of compounds which are inhibitors of interleukin-1β converting enzyme. The ICE inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting ICE activity and consequently, may be advantageously used as agents against IL-1-, apoptosis-, IGIF-, and IFN-γ-mediated diseases, inflammatory diseases, autoimmune diseases, destructive bone disorders, proliferative disorders, infectious diseases, degenerative diseases, and necrotic diseases. This invention also relates to methods for inhibiting ICE activity, for treating interleukin-1-, apoptosis-, IGIF- and IFN-γ-mediated diseases and decreasing IGIF and IFN-γ production using the compounds and compositions of this invention. This invention also relates to methods for preparing N-acylamino compounds. | 07-21-2011 |
20120165319 | INHIBITORS OF INTERLEUKIN-1 BETA CONVERTING ENZYME - The present invention relates to novel classes of compounds which are inhibitors of interleukin-1β converting enzyme. The ICE inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting ICE activity and consequently, may be advantageously used as agents against IL-1-, apoptosis-, IGIF-, and IFN-γ-mediated diseases, inflammatory diseases, autoimmune diseases, destructive bone disorders, proliferative disorders, infectious diseases, degenerative diseases, and necrotic diseases. This invention also relates to methods for inhibiting ICE activity, for treating interleukin-1-, apoptosis-, IGIF- and IFN-γ-mediated diseases and decreasing IGIF and IFN-γ production using the compounds and compositions of this invention. This invention also relates to methods for preparing N-acylamino compounds. | 06-28-2012 |
20140057257 | IN VITRO METHOD FOR THE PROGNOSIS OF PROGRESSION OF A CANCER AND OF THE OUTCOME IN A PATIENT AND MEANS FOR PERFORMING SAID METHOD - The present invention relates to the prognosis of the outcome of a cancer in a patient, which prognosis is based on the quantification of one or several biological markers that are indicative of the presence of, or alternatively the level of, the adaptive immune response of said patient against said cancer. | 02-27-2014 |
20150268245 | IN VITRO METHOD FOR THE PROGNOSIS OF PROGRESSION OF A CANCER AND OF THE OUTCOME IN A PATIENT AND MEANS FOR PERFORMING SAID METHOD - The present invention relates to the prognosis of the outcome of a cancer in a patient, which prognosis is based on the quantification of one or several biological markers that are indicative of the presence of, or alternatively the level of, the adaptive immune response of said patient against said cancer. | 09-24-2015 |
Wolf Herve Fridman, Paris FR
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20100196418 | UNIVERSAL CARRIER FOR TARGETING MOLECULES TO Gb3 RECEPTOR EXPRESSING CELLS - The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein: | 08-05-2010 |
20150045536 | UNIVERSAL CARRIER FOR TARGETING MOLECULES TO GB3 RECEPTOR EXPRESSING CELLS - The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein: | 02-12-2015 |