Patent application number | Description | Published |
20100011207 | Service Oriented Architecture Device - A system for Service Oriented Architecture (SOA) communication includes a plurality of SOA nodes having a standardized hardware configuration, wherein the standardized hardware configuration includes an operating engine, an encryption module accessed by the operating engine, which provides security for message traffic, a compression module to compress and decompress the message traffic, a routing module accessed by the operating engine, to determine the routing of message types, incoming traffic routed to appropriate service clients, outbound traffic routed to appropriate SOA devices, a security module that authenticates and authorizes message traffic, and one or more network interfaces, and one or more networks over which the SOA nodes communicate with one another. | 01-14-2010 |
20100332429 | SYSTEM AND METHOD FOR OPTIMIZING A SEQUENTIAL ARRANGEMENT OF ITEMS - A system optimizing a sequence according to an algorithm includes: an initiator; a tracker; a generator; a measurer; a regulator; and an output. The initiator provides initial sequences to the tracker. The tracker stores and effects a statistical treatment of the initial sequences. The generator employs the statistical treatment to present a new sequence. The measurer evaluates the new sequence according to the algorithm. The measurer provides the new sequence to the tracker when the evaluating indicates so, and provides the new sequence and a quality indicator to the regulator. The regulator employs the indicator to store at least a best-sequence-yet-received, and responds to a criterion to order the generator to present a new sequence or to present the best-sequence-yet-received at the output. | 12-30-2010 |
20140025610 | BENCHMARKING PROGRESSIVE SYSTEMS FOR SOLVING COMBINATORIAL PROBLEMS - A system is provided for benchmarking a progressive combinatorial solver. The system may initialize a parametric model collector, and perform a plurality of parametric trials associated with respective numbers of sub-part iterations of the progressive combinatorial solver. For each of the plurality of parametric trials, the system may initialize a statistical data collector. The system may perform a plurality of randomized executions of the progressive combinatorial solver, and add data including metric values for respective solutions of the executions to the statistical data collector. The system may then determine statistical parameter(s) of data in the statistical data collector, and add data including an indication of the respective number of sub-part iterations, a cost of finding the metric values for the respective solutions, and the statistical parameters of the trial to the parametric data collector. And the system may determine a best-fit model from data in the parametric data collector. | 01-23-2014 |
20140379401 | BENCHMARKING PROGRESSIVE SYSTEMS FOR SOLVING COMBINATORIAL PROBLEMS - A system is provided for benchmarking a progressive combinatorial solver. The system may initialize a parametric model collector, and perform a plurality of parametric trials associated with respective numbers of sub-part iterations of the progressive combinatorial solver. For each of the plurality of parametric trials, the system may initialize a statistical data collector. The system may perform a plurality of randomized executions of the progressive combinatorial solver, and add data including metric values for respective solutions of the executions to the statistical data collector. The system may then determine statistical parameter(s) of data in the statistical data collector, and add data including an indication of the respective number of sub-part iterations, a cost of finding the metric values for the respective solutions, and the statistical parameters of the trial to the parametric data collector. And the system may determine a best-fit model from data in the parametric data collector. | 12-25-2014 |
Patent application number | Description | Published |
20090078362 | PROCESS FOR FORMING CURVED THERMOPLASTIC COMPOSITE MATERIAL - A process for forming curved thermoplastic composite material. According to an illustrative embodiment, the process includes providing a length of straight thermoplastic material; pre-forming the length of straight thermoplastic material into a selected cross-sectional configuration; pressing the length of the straight thermoplastic material; and imparting a curved shape to the length of straight thermoplastic material by providing a curved section and passing the length of straight thermoplastic material through the curved section of a process assembly. | 03-26-2009 |
20100225016 | TOOL SLEEVE FOR MOLD DIE AND METHOD OF MOLDING PARTS USING THE SAME - A device changes the shape of a die used to compression mold a part. The device includes a sleeve placed between the die and a charge to be molded. The sleeve has an inner face generally conforming to a face of the die, and a outer face for molding a part. | 09-09-2010 |
20100319841 | NOVEL FABRICATION PROCESS FOR THERMOPLASTIC COMPOSITE PARTS - A fabrication method of forming a thermoplastic composite laminate material with tailored and varying thickness in a continuous process. This process utilizes automated equipment or hand lay-up to collate parts or components into a multi-layer stack. Each stack contains all plies, including ply build-up areas, tacked in the proper location to maintain orientation and location. The consolidation tooling contains all necessary part features and is coordinated to the customized multiple ply stacks to form a single integrated thermoplastic composite laminate potentially having areas of differing thickness from these multiple ply stacks. | 12-23-2010 |
20130126076 | Method for Fabricating Thermoplastic Composite Parts - A fabrication method of forming thermoplastic composite laminate parts with tailored and varying thickness in a continuous process. Automated equipment or hand lay-up are used to collate parts or components into a multi-layer stack. Each stack contains all plies, including ply build-up areas, tacked in the proper location to maintain orientation and location. Ply consolidation tooling contains all necessary part features and is coordinated to the customized multiple ply stacks to form a single integrated thermoplastic composite laminate potentially having areas of differing thickness from the multiple ply stacks. | 05-23-2013 |
20140014274 | METHOD AND MATERIAL EFFICIENT TOOLING FOR CONTINUOUS COMPRESSION MOLDING - Thermoplastic laminates are fabricated in a continuous compression molding production line. A lay-up of laminate plies is placed in a recess on a carrying tool, and the tool is moved through successive forming operations on the line, including preforming and consolidation operations. The tool is separated from the fully formed part at the end of the line and may be reused. Use of the carrying tool reduces material scrap. | 01-16-2014 |
20140314894 | TOOL SLEEVE FOR MOLD DIE - A device changes the shape of a die used to compression mold a part. The device includes a sleeve placed between the die and a charge to be molded. The sleeve has an inner face generally conforming to a face of the die, and a outer face for molding a part. | 10-23-2014 |
Patent application number | Description | Published |
20120141614 | Protection Against Sunburn and Skin Problems With Orally-Ingested High-Dosage Zeaxanthin - A carotenoid substance called zeaxanthin, when ingested orally at suitable dosages such as 30 to 100 mg/day for a span of 1 to 2 weeks, can provide effective protection against sunburns, and can give skin a darker tint that emulates a healthy suntan. In tests involving adults, it was found that zeaxanthin dosages of 30 to about 80 mg per day were sufficient to induce: (i) a mild but noticeable tinting, shading, or darkening of skin color, comparable to a mild suntan; (ii) a substantial increase in the person's ability to withstand elevated levels of sun or UV exposure; and, (iii) an increased ability of reddened and sunburned skin to convert into intact skin that looks browned and healthily tanned. Oral ingestion of dosages of zeaxanthin after a noticeable darkening of the skin has been achieved further enhances a tanned appearance and/or protects against sun damage. | 06-07-2012 |
20120282204 | Protection Against Sunburn And Skin Problems With Topical And Orally-Ingested Dosages Of Zeaxanthin - A carotenoid substance called zeaxanthin, when ingested orally at suitable dosages such as 30 to 100 mg/day for a span of 1 to 2 weeks, can provide effective protection against sunburns, and can give skin a darker tint that emulates a healthy suntan. In tests involving adults, it was found that zeaxanthin dosages of 30 to about 80 mg per day were sufficient to induce: (i) a mild but noticeable tinting, shading, or darkening of skin color, comparable to a mild suntan; (ii) a substantial increase in the person's ability to withstand elevated levels of sun or UV exposure without any subsequent pain or discomfort, and without the subsequent peeling and flaking that characterizes sunburns; and, (iii) an increased ability of reddened and sunburned skin to convert into intact skin that looks browned and healthily tanned. By reducing the amount of exposure to sunlight (or tanning lights) that are required to achieve a desired level of tanning, zeaxanthin can reduce the risks of skin cancer, premature aging or wrinkling, and similar skin problems. Since zeaxanthin also has retina-protecting properties and reduces the risk of a disease called macular degeneration, oral ingestion of these dosages of a zeaxanthin to enhance a tanned appearance and/or to protect against sun damage is believed to pose no health risks, and can offer several benefits due to the anti-oxidant and other activities of zeaxanthin. | 11-08-2012 |
20130281545 | Protection Against Sunburn And Skin Problems With Topical And Orally-Ingested Dosages Of Zeaxanthin - A carotenoid substance called zeaxanthin, when ingested orally at suitable dosages such as 30 to 100 mg/day for a span of 1 to 2 weeks, can provide effective protection against sunburns, and can give skin a darker tint that emulates a healthy suntan. In tests involving adults, it was found that zeaxanthin dosages of 30 to about 80 mg per day were sufficient to induce: (i) a mild but noticeable tinting, shading, or darkening of skin color, comparable to a mild suntan; (ii) a substantial increase in the person's ability to withstand elevated levels of sun or UV exposure without any subsequent pain or discomfort, and without the subsequent peeling and flaking that characterizes sunburns; and, (iii) an increased ability of reddened and sunburned skin to convert into intact skin that looks browned and healthily tanned. By reducing the amount of exposure to sunlight (or tanning lights) that are required to achieve a desired level of tanning, zeaxanthin can reduce the risks of skin cancer, premature aging or wrinkling, and similar skin problems. Since zeaxanthin also has retina-protecting properties and reduces the risk of a disease called macular degeneration, oral ingestion of these dosages of a zeaxanthin to enhance a tanned appearance and/or to protect against sun damage is believed to pose no health risks, and can offer several benefits due to the anti-oxidant and other activities of zeaxanthin. | 10-24-2013 |
Patent application number | Description | Published |
20140283675 | OPERATIONAL CONTROL LOGIC FOR HARMONIZED TURRET WITH GIMBALED SUB-SYSTEMS - Methods are disclosed for controlling a turret assembly with two or more gimbaled, swivel assembly sub-systems, such as a gimbaled gun and a gimbaled electro-optical sensor. The turret can be automatically slewed in response to one of the swivel assemblies rotating. A user can switch turret modes reflecting a priority between the gimbaled sub-systems system so that one takes priority over the other(s) during a mission. | 09-25-2014 |
20150025801 | GYRO DRIFT CANCELATION - Methods, devices, and systems are presented for compensating for gyroscopic drift in a stabilized gimbal system mounted on a vehicle. When the vehicle is parked and the gimbal is not being commanded to move by an operator, encoders or resolvers of the gimbal stabilized system are read and periodically read thereafter. When the vehicle begins to move or the gimbal is commanded to move, the last periodic reading of the resolvers is used to determine the amount that the gimbal has moved during the rest period. A gyroscopic drift rate is computed by dividing the amount of angular movement by the time period between the readings, and the gyroscopic drift rate is used for corrections while the vehicle is moving or gimbal is commanded to move. Each time the vehicle stops, the gyroscopic drift rate is re-computed and updated. The gyroscope can be heated until the drift rate is constant with respect to temperature, further helping the calibration. | 01-22-2015 |
20150059567 | HARMONIZED TURRET WITH MULTIPLE GIMBALED SUB-SYSTEMS - Multiple independently gimbaled devices, such as an electro-optical sensor and machine gun, are mounted to a rotating platform on a vehicle. The platform can rotate to prevent one device from blocking the other while aiming at an off-board location. A control system can harmonize the rotation of the device gimbals and rotating platform so that they remain pointed at the same location. The platform can be rotated to place a firing weapon downwind of a sensor or otherwise compensate for effects of one on the other. | 03-05-2015 |
Patent application number | Description | Published |
20100093560 | COMBINED AUTOMATED PARALLEL SYNTHESIS OF POLYNUCLEOTIDE VARIANTS - The present disclosure relates to methods for efficient synthesis, cloning, transformation and screening of large diverse libraries of polynucleotide variants comprising well-defined nucleotide differences relative to a reference polynucleotide. | 04-15-2010 |
20110029468 | METHOD OF GENERATING AN OPTIMIZED, DIVERSE POPULATION OF VARIANTS - The present disclosure relates to methods of rapidly and efficiently searching biologically-related data space to identify a population set maximally diverse and optimized for sets of desired properties. More specifically, the disclosure provides methods of identifying a diverse, evolutionary separated bio-molecules with desired properties from complex bio-molecule libraries. The disclosure additionally provides digital systems and software for performing these methods. | 02-03-2011 |
20110034342 | METHOD OF GENERATING AN OPTIMIZED, DIVERSE POPULATION OF VARIANTS - The disclosure relates to a method of generating a diverse set of variants to screen improved and novel properties within the variant population, a system for creating the diverse set of variants, and the variant peptides. | 02-10-2011 |
20110082055 | REDUCED CODON MUTAGENESIS - Methods and compositions that reduce complexity of libraries of variant biological molecules, that reduce oversampling of these libraries during screening and that improve screening efficiency are provided. Sets of efficient degenerate codon sets are provided that efficiently encode all, or nearly all canonical amino acids. Degenerate oligonucleotides comprising these codons are provided, as are polynucleotide variants. Variant pooling strategies are used during library construction. Logical filtering is applied to select codon sites for mutagenesis, or to select amino acid sets to be incorporated at such sites. Methods for reducing non-optimal oversampling during screening are provided. | 04-07-2011 |
20130143767 | COMBINED AUTOMATED PARALLEL SYNTHESIS OF POLYNUCLEOTIDE VARIANTS - The present disclosure relates to methods for efficient synthesis, cloning, transformation and screening of large diverse libraries of polynucleotide variants comprising well-defined nucleotide differences relative to a reference polynucleotide. | 06-06-2013 |
20140256557 | METHOD OF GENERATING AN OPTIMIZED, DIVERSE POPULATION OF VARIANTS - The disclosure relates to a method of generating a diverse set of variants to screen improved and novel properties within the variant population, a system for creating the diverse set of variants, and the variant peptides. | 09-11-2014 |
20150024971 | COMBINED AUTOMATED PARALLEL SYNTHESIS OF POLYNUCLEOTIDE VARIANTS - The present disclosure relates to methods for efficient synthesis, cloning, transformation and screening of large diverse libraries of polynucleotide variants comprising well-defined nucleotide differences relative to a reference polynucleotide. | 01-22-2015 |
Patent application number | Description | Published |
20090298125 | HALOHYDRIN DEHALOGENASES AND RELATED POLYNUCLEOTIDES - The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods. | 12-03-2009 |
20090312196 | METHOD OF SYNTHESIZING POLYNUCLEOTIDE VARIANTS - The present disclosure relates to methods for generating libraries of polynucleotide variants comprising defined nucleotide differences relative to a reference polynucleotide. | 12-17-2009 |
20100099143 | Alanine 2,3-aminomutases and related polynucleotides - The present invention is directed to polypeptides that have enhanced alanine 2,3-aminomutase (AAM) activity and/or thermostability relative to the wild-type enzymes that have incidental AAM activity as a result of cross reactivity with alanine. In addition, the present invention is directed to a polynucleotides that encodes for the AAM polypeptides of the present invention, to nucleic acid sequences comprising the polynucleotides, to expression vectors comprising the polynucleotides operatively linked to a promoter, to host cells transformed to express the AAM polypeptides, and to a method for producing the AAM polypeptides of the present invention. | 04-22-2010 |
20100248312 | Alanine 2,3-aminomutases and related polynucleotides - The present disclosure relates generally to polypeptides having improved alanine 2,3-aminomutase (AAM) activity, the polynucleotides encoding the AAM polypeptides, and expression vectors and host cells for expressing the AAM polypeptides. | 09-30-2010 |
20120040437 | ALANINE 2,3-AMINOMUTASES AND RELATED POLYNUCLEOTIDES - The present disclosure relates generally to polypeptides having improved alanine 2,3-aminomutase (AAM) activity, the polynucleotides encoding the AAM polypeptides, and expression vectors and host cells for expressing the AAM polypeptides. | 02-16-2012 |
Patent application number | Description | Published |
20100167345 | HALOHYDRIN DEHALOGENASES AND RELATED POLYNUCLEOTIDES - The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods. | 07-01-2010 |
20110257023 | METHODS, SYSTEMS, AND SOFTWARE FOR IDENTIFYING FUNCTIONAL BIOMOLECULES - The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods. | 10-20-2011 |
20120208259 | Halohydrin Dehalogenases and Related Polynucleotides - The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods. | 08-16-2012 |