Patent application number | Description | Published |
20120258870 | Methods, Systems, and/or Use of Oligonucleotide Conjugates to Develop Panels for Use in Assays and Detections - The present disclosure is directed to methods systems, and/or uses of oligonucleotide conjugates to develop panels for use in assays and detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein. | 10-11-2012 |
20120258880 | Methods and/or Use of Oligonucleotide Conjugates for Assays and Flow Cytometry Detections - The present disclosure is directed to methods and/or uses of oligonucleotide conjugates for assays and flow cytometry detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein. | 10-11-2012 |
20120258881 | Methods and/or Use of Oligonucleotide Conjugates for Assays and Microscopy/Imaging Detections - The present disclosure is directed to methods and/or uses of oligonucleotide conjugates for assays and microscopy/imaging detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein. | 10-11-2012 |
20130035259 | Methods and/or Systems Producing and Providing Sets of Oligonucleotide Conjugates for Assays and Detections - The present disclosure is directed to methods and/or systems producing and providing uses sets of oligonucleotide conjugates for assays and detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein. | 02-07-2013 |
20130123121 | Methods and/or Use of Oligonucleotide-Bead Conjugates for Assays and Detections - The present disclosure is directed to methods and/or uses of oligonucleotide-bead conjugates for assays and detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein. | 05-16-2013 |
20130184184 | Methods and/or Use of Oligonucleotide Conjugates Having Varied Degrees of Labeling for Assays and Detections - The present disclosure is directed to methods and/or uses of oligonucleotide conjugates having varied degrees of labeling for assays and detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein. | 07-18-2013 |
20130344508 | Methods and/or Use of Oligonucleotide Conjugates for Suppressing Background Due to Cross-Hybridization - The present disclosure is directed to methods and/or uses of oligonucleotide conjugates for assays and detections and related systems and/or kits for suppressing background due to cross-hybridization. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein. | 12-26-2013 |
Patent application number | Description | Published |
20110320498 | Systems and Methods for Optimizing Very Large N-Gram Collections for Speed and Memory - A computer memory stores a data structure representing a ternary search tree (TST) representing multiple word n-grams for a corpus of documents. The data structure includes plural records in a first memory, each record representing a node of the TST and comprising plural fields. At least some n-grams have a sequence of units. The plurality of fields includes one for identifying a given unit of the sequence for a given node, one reserved for storing payload information for the given node, and plural child fields reserved for storing information for a first, second and third child nodes of the given node. The child fields store a null value indicating the absence of the child node or an identifier identifying a memory location of the child node. For at least one record, at least one of the child fields stores an identifier identifying a memory location of a memory different than the first memory. | 12-29-2011 |
20140234810 | Systems and Methods for Determining Text Complexity - Computer-implemented systems and methods are provided for determining a document's complexity. For example, a computer performing the complexity analysis can receive a document. The computer can determine the content words within the document and determine an association measure for each group of content words. An association profile can be created for the document using the association measures. The computer can use the association profile to determine the complexity of the document. The complexity of the document may correspond to the document's suitable reading level or, if the document is an essay, an essay score. | 08-21-2014 |
20140295399 | Systems and Methods for Evaluating Susceptibility of Automated Scoring Engines to Gaming Behavior - Systems and methods are provided for determining a susceptibility of a computer-implemented automated scoring engine to gaming strategies. A plurality of responses to a prompt are provided to a computer-implemented automated scoring engine to receive a first set of scores. A first transformation is performed on each of the plurality of responses to generate a first set of transformed responses. The first set of transformed responses is provided to the computer-implemented automatic scoring engine to receive a second set of scores, and a gaming susceptibility metric is determined based on the first set of scores and the second set of scores. | 10-02-2014 |
20140343923 | Systems and Methods for Assessing Constructed Recommendations - A computer-implemented method of training an assessment model for assessing constructed texts expressing opinions on subjects includes accessing a plurality of training texts, which are constructed texts. The training texts are analyzed with the processing system to derive values of a plurality of linguistic features of an assessment model. At least one of the plurality of linguistic features relates to sentiment and at least one of the plurality of linguistic feature relates to specificity. The assessment model is trained with the processing system based on the values of the plurality of linguistic features. Based on the training, a weight for each of the plurality of linguistic features is determined. The assessment model is calibrated to include the weights for at least some of the plurality of linguistic features such that the assessment model is configured to generate assessment measures for constructed texts expressing opinions on subjects. | 11-20-2014 |
20150254565 | Systems and Methods for Constructed Response Scoring Using Metaphor Detection - Systems and methods described herein utilize supervised machine learning to generate a figure-of-speech prediction model for classify content words in a running text as either being figurative (e.g., as a metaphor, simile, etc.) or non-figurative (i.e., literal). The prediction model may extract and analyze any number of features in making its prediction, including a topic model feature, unigram feature, part-of-speech feature, concreteness feature, concreteness difference feature, literal context feature, non-literal context feature, and off-topic feature, each of which are described in detail herein. Since uses of figure of speech in writings may signal content sophistication, the figure-of-speech prediction model allows scoring engines to further take into consideration a text's use of figure of speech when generating a score. | 09-10-2015 |
20150347385 | Systems and Methods for Determining Lexical Associations Among Words in a Corpus - Systems and methods are provided for identifying one or more target words of a corpus that have a lexical relationship to a plurality of provided cue words. The cue words and statistical lexical information derived from a corpus of documents are analyzed to determine candidate words that have a lexical association with the cue words. The statistical information includes numerical values indicative of probabilities of word pairs appearing together as adjacent words in a well-formed text or appearing together within a paragraph of a well-formed text. For each candidate word, a statistical association score between the candidate word and each of the cue words is determined. An aggregate score for each of the candidate words is determined based on the statistical association scores. One or more of the candidate words are selected to be the one or more target words based on the aggregate scores. | 12-03-2015 |
Patent application number | Description | Published |
20130018781 | MERCHANT DATA CLEANSING IN CLEARING RECORD - A network operator intermediates a cashless transaction by sending a payment device issuer an outbound clearing data file enriched with cleansed merchant data. Issuers that choose to participate in the merchant data cleansing service will be provided with the cleansed, and optionally augmented, merchant information. Providing this data to the issuer could be used to help reduce costs associated with “do not recognize” calls by cardholders, disputed charges, and charge-backs. With cleansed data provided in the clearing record, a device holder would be given access to this cleansed information about the merchant where a transaction took place through their statement. The present disclosure also provides for augmenting the clearing record data to include merchant-specific add-on and/or aggregate data not presently included in the transaction clearing record, yet useful to the issuer both in form and content. | 01-17-2013 |
20140114848 | MERCHANT DATA CLEANSING IN CLEARING RECORD - A network operator intermediates a cashless transaction by sending a payment device issuer an outbound clearing data file enriched with cleansed merchant data. Issuers that choose to participate in the merchant data cleansing service will be provided with the cleansed, and optionally augmented, merchant information. Providing this data to the issuer could be used to help reduce costs associated with “do not recognize” calls by cardholders, disputed charges, and charge-backs. With cleansed data provided in the clearing record, a device holder would be given access to this cleansed information about the merchant where a transaction took place through their statement. The present disclosure also provides for augmenting the clearing record data to include merchant-specific add-on and/or aggregate data not presently included in the transaction clearing record, yet useful to the issuer both in form and content. | 04-24-2014 |