Patent application number | Description | Published |
20090317852 | Engineered Cell Growth on Polymeric Films and Biotechnological Applications Thereof - A free-standing thin film is fabricated from a structure comprising a base layer coated with a sacrificial polymer layer, which is in turn coated with a flexible polymer layer. Cells are then seeded onto the flexible polymer layer and cultured to form a tissue. The flexible polymer layer is then released from the base layer to produce a free-standing thin film comprising the tissue on the flexible polymer layer. In one embodiment, the cells are myocytes, which can be actuated to propel or displace the free-standing film. In another embodiment, the free-standing film is used to treat injured human tissue. | 12-24-2009 |
20100126404 | Surface Topographies for Non-Toxic Bioadhesion Control - An article has a surface topography for resisting bioadhesion of organisms and includes a base article having a surface. A composition of the surface includes a polymer. The surface has a topography comprising a pattern defined by a plurality of spaced apart features attached to or projected into the base article. The plurality of features each have at least one microscale dimension and at least one neighboring feature having a substantially different geometry. An average feature spacing between adjacent ones of the features is between 10 μm and 100 μm in at least a portion of the surface. The surface topography can be numerically represented using at least one sinusoidal function. In one embodiment, the surface can comprise a coating layer disposed on the base article. | 05-27-2010 |
20100196432 | BIOPOLYMER STRUCTURES - The invention described herein relates to biopolymer structures. The biopolymer structures are spatially organized from the nanometer to centimeter length scales and incorporate functionally active cells. Applications of the biopolymer structures include use with stem cells. | 08-05-2010 |
20100330644 | BOUNDARY CONDITIONS FOR THE ARRANGEMENT OF CELLS AND TISSUES - The present invention relates to the arrangement of one or more cells in a medium or on a substrate through the use of boundary conditions, which are changes in local environment compared to the medium or substrate alone or cause an alteration of cell response upon interaction of a cell with the boundary condition. | 12-30-2010 |
20110189719 | METHODS OF GENERATING PATTERNED SOFT SUBSTRATES AND USES THEREOF - The present invention provides methods of generating and devices of patterned soft substrates, on which cells may be seeded, as well as methods of using these substrates. Devices containing these patterned soft substrates are also provided. | 08-04-2011 |
Patent application number | Description | Published |
20090164634 | Automatic Intranet and Internet Detection for Enhanced Browsing and Information Discovery within Collaborative Applications - A computer-implemented method of managing bookmarks within a collaborative application can include receiving a user input specifying a universal resource locator (URL) to be bookmarked and determining whether a bookmark record including the URL exists. Responsive to determining that a bookmark record including the URL does not exist, an address and a network type for the URL can be determined. A bookmark record including the URL and the network type can be stored. | 06-25-2009 |
20100131666 | System and Method for Managing Data Transfers Between Information Protocols - A computer data handling method, system and apparatus are disclosed. A data item or information object are received in one protocol. Based on data contents, a protocol transfer module (engine) optimizes information presentation by transferring/converting the data item from the one protocol to a form of the data item in a different protocol. The resulting form (i.e. the data item/information object in the different protocol) optimally presents the data contents to an end-user. The end user reads the converted data item in the different protocol. The invention system enables the user to reply or otherwise further handle the data item in the initial protocol as desired. The initial protocol may be email and the resulting form of the data item may be one or more feed entries in machine-readable feeds specified by the user. The invention optimization effectively reduces email In-box clutter and streamlines reading in feed readers. | 05-27-2010 |
20120131499 | COMPUTER METHOD AND SYSTEM FOR TOPOGRAPHICAL REPRESENTATION OF TEXTUAL DATA - Computer system, method and apparatus generate and display a graphical representation of a body of text. The graphical representation serves as a text map allowing navigation operations and other user interaction. The text map enables improved navigation of the body of text. Computer-based geographic mapping operations (e.g., zoom, pan, highlight, etc.) are used to navigate the text. The text map may have various graphical feature overlays also navigable by and interactive to the user. | 05-24-2012 |
20130239021 | RECEIVING AND PRESENTING DETAILED ACTIVITY INFORMATION REGARDING CURRENT AND RECENT INSTANT MESSAGING SESSIONS OF REMOTE USERS - A system for providing a local computer user with detailed activity information regarding remote users, in order to assist the local user in determining whether to initiate a communication session with a remote user. The system provides activity information that may describe the number of instant messaging sessions one or more remote users are currently involved in, the identities of participants in those sessions, activity levels, time period information, and other information. The system further provides detailed activity information describing recent instant messaging sessions of one or more remote users. | 09-12-2013 |
Patent application number | Description | Published |
20100016938 | DIAGNOSING, MONITORING AND TREATING INFLAMMATION - The present invention provides methods and compositions for treating chronic inflammatory disease in a subject and associated pharmaceutical compositions, medical devices and systems. | 01-21-2010 |
20130102546 | METHODS OF TREATING VASCULAR INFLAMMATORY DISORDERS - Provided are methods of treating or delaying the onset of a vascular inflammatory disease (e.g., acute lung injury) in a subject including administering to the subject a therapeutically effective amount of a nucleic acid containing all or a part of the sequence of mature miR-181b (SEQ ID NO: 1). Also provided are methods of decreasing nuclear factor-R? (NF-R?) signaling in an endothelial cell including administering to the subject a nucleic acid containing all or a part of the sequence of mature miR-181b (SEQ ID NO: 1). | 04-25-2013 |
20140121262 | Methods of Using microRNA-26a to Promote Angiogenesis - Methods for promoting angiogenesis, and for diagnosing the presence or risk of developing disorders associated with impaired angiogenesis or blood flow to a tissue in the body, using microRNA-26a (miR-26a). | 05-01-2014 |
20140162947 | Kruppel-like Factor 10 (KLF10) as a Biomarker of Endothelial Progenitor Cell Dysfunction - The use of Kruppel-like Factor (KLF10) as a diagnostic and prognostic tool for peripheral artery disease and other disease conditions associated with reduced angiogenesis or endothelial progenitor cell dysfunction such as diabetes and stent thrombosis. | 06-12-2014 |
20150152418 | METHODS OF TREATING VASCULAR INFLAMMATORY DISORDERS - Provided are methods of treating or delaying the onset of a vascular inflammatory disease (e.g., acute lung injury) in a subject including administering to the subject a therapeutically effective amount of a nucleic acid containing all or a part of the sequence of mature miR-181b (SEQ ID NO: 1). Also provided are methods of decreasing nuclear factor-κβ (NF-κβ) signaling in an endothelial cell including administering to the subject a nucleic acid containing all or a part of the sequence of mature miR-181b (SEQ ID NO: 1). | 06-04-2015 |