Ewa
Ewa Aneta Glowacz, Madrid ES
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20130101801 | OPTIMIZED STRINGER RUN-OUT ZONES IN AIRCRAFT COMPONENTS - Aircraft component, such as an aircraft wing, that comprises at least one panel ( | 04-25-2013 |
Ewa Bardasz, Mentor, OH US
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20090064956 | Ashless Consumable Engine Oil - The present invention relates to a low sulfur, low phosphorus, low-ash, zinc free consumable lubricant composition suitable for use in an internal combustion engine, comprising: an oil of lubricating viscosity containing less than 0.01 percent by weight of sulfur; a high TBN succinimide dispersant and overall all lubricant composition that has a sulfated ash value of up to about 0.2, a phosphorus content of up to about 50 to about 800 ppm and a sulfur content of up to about 0.4 percent by weight. | 03-12-2009 |
20100101518 | LUBRICANT FOR HYDROGEN-FUELED ENGINES - A lubricant composition of a synthetic oil of lubricating viscosity, 3 to 6 percent by weight of a nitrogen-containing dispersant, 1 to 2.5 weight percent of an overbased magnesium detergent, 1 to 5 weight percent of an antioxidant; and 0.25 to 1.5 weight percent of a friction modifier is useful for lubricating a hydrogen-fueled engine. The composition will typically contain less than 0.01 weight percent Ca, less than 0.01 weight percent Zn, less than 0.06 weight percent P, and will have a sulfated ash level of less than 1.2%. | 04-29-2010 |
Ewa Bogel, Belfast GB
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20090216015 | Base Stable Ionic Liquids - The present invention relates to novel base stable ionic liquids and uses thereof as solvents in chemical reactions, especially base catalysed chemical reactions and reactions comprising the use of strong basis. | 08-27-2009 |
Ewa Cichacz, Phoenix, AZ US
Ewa Dominowska, Bellevue, WA US
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20090319555 | OPTIMIZING DOCUMENTS BASED ON DESIRED CONTENT - Embodiments of the present invention relate to methods and computer storage media for optimizing the content of an online publisher. The content of the publisher is received. A category for each page of the publisher's content is determined. Desired content information and desired keyword information are received. A content deficiency of the publisher's content is determined based on at least one of the desired content or the desired keyword information. An optimization plan is created to improve the content deficiency of the publisher's content. The optimization plan is presented. In additional embodiments of the present invention, the layout of the publisher's content is analyzed and optimized. In an additional exemplary embodiment of the present invention, content modules are manipulated to optimize the publisher's content. | 12-24-2009 |
Ewa Dudzic, Warszawa PL
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20150366413 | CLEANSING TEXTILE DEVICE ESPECIALLY FOR MAKEUP REMOVAL - The invention relates to a cleansing textile device, which contains a cleaning element which comprises T-shaped, L-shaped, Y-shaped, X-shaped, or otherwise shaped loops of synthetic fibers consisting of one or more types of synthetic materials, fixed axially in relation to the fiber, where the diameter of a single fiber ranges from 500 nm to 20μm and the thickness of the fiber loop is 50 to 2,000 nm. | 12-24-2015 |
Ewa Dudzid, Warszawa PL
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20150366413 | CLEANSING TEXTILE DEVICE ESPECIALLY FOR MAKEUP REMOVAL - The invention relates to a cleansing textile device, which contains a cleaning element which comprises T-shaped, L-shaped, Y-shaped, X-shaped, or otherwise shaped loops of synthetic fibers consisting of one or more types of synthetic materials, fixed axially in relation to the fiber, where the diameter of a single fiber ranges from 500 nm to 20μm and the thickness of the fiber loop is 50 to 2,000 nm. | 12-24-2015 |
Ewa Dworniczek, Wroclaw PL
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20140220091 | EMBEDDING NANOPARTICLES IN THERMOPLASTIC POLYMERS - The present invention relates to a polymeric material having one or more nanoparticles embedded within the surface layer of a single side of the material. In some embodiments, the nanoparticles are microbiocidal nanoparticles which impart antimicrobial characteristics to the polymeric material within which they sprayed and pushed by are embedded. | 08-07-2014 |
Ewa Gebauer-Henke, Aachen DE
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20150218082 | PROCESS FOR HYDROGENATING AROMATIC DI- AND POLYAMINES - A catalytic process for hydrogenating aromatic di- and polyamines with the aid of a selected catalyst system is provided, which comprises a mixture of a first heterogeneous catalyst and a second heterogeneous catalyst and a nitro compound (nitrate and/or nitrite salt). The first and second heterogeneous catalyst each independently comprise a metal selected from the group consisting of Cr, Mo, W, Mn, Re, Fe, Ru, Os, Co, Rh, Ir, Ni, Pd and/or Pt and the metal selected for the second heterogeneous catalyst is different from the metal selected for the first heterogeneous catalyst. Hydrogenation of aromatic rings having two or more amino groups bound to the aromatic ring produces cycloaliphatic di- and polyamines, which are useful chemical intermediates, e.g., for further reaction with epoxides or isocyanates. The amino groups may also be converted to isocyanates via reaction with phosgene. The resulting cycloaliphatic di- and polyisocyanates may also be used as monomers for making polymers. | 08-06-2015 |
20150218083 | PROCESS FOR HYDROGENATING AROMATIC DI- AND POLYAMINES TO CYCLOALIPHATIC DI- AND POLYAMINES - A process for hydrogenating aromatic di- and polyamines is provided comprising the steps of reacting the aromatic amine with hydrogen in the presence of a catalytic system, wherein the catalytic system comprises a heterogeneous catalyst comprising a metal selected from the group consisting of Cr, Mo, W, Mn, Re, Fe, Ru, Os, Co, Rh, Ir, Ni, Pd and/or Pt and a support, and wherein the catalyst system further comprises an organic nitro compound. Hydrogenation of aromatic di- and polyamines having two or more amino groups bound to the aromatic ring produces cycloaliphatic di- and polyamines, which are useful chemical intermediates, e.g., for further reaction with epoxides or isocyanates. The amino groups may also be converted to isocyanates via reaction with phosgene. The resulting cycloaliphatic di- and polyisocyanates may also be used as monomers for making polymers. | 08-06-2015 |
Ewa Goslawska-Goedecke, West Chester, PA US
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20080249992 | Cross-language searching - Methods and apparatus, including computer program products, related to cross-language searching. Input characterizing search criteria in a first language may be received and a search may be performed on a database having records in a second language. The search may be performed on the database with synonyms of the search criteria that are in the second language. A user may be able to select or edit search criteria in the second language from suggested search criteria. Context information may be used to find search criteria in the second language or results that may be more relevant. The results may be translated for a user to the first language. | 10-09-2008 |
Ewa Gruszecka-Kowalik, Atlanta, GA US
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20130172313 | Carbapenem Antibacterials with Gram-Negative Activity - The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. | 07-04-2013 |
20150306071 | Carbapenem Antibacterials with Gram-Negative Activity - The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. | 10-29-2015 |
Ewa Grzybowska, Arlington, VA US
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20100280977 | System, Program, and Method for Representation, Utilization, and Maintenance of Regulatory Knowledge - A knowledge based system, program, and method for regulatory knowledge representation, utilization, and maintenance is presented. The system, program, and method support advanced reasoning concerning entities and events in order to determine their adherence to regulations and policies, with the specific ability to identify violations of regulations that govern industries such as the financial services industry. Advanced approaches and methods that allow for efficient representation of regulatory knowledge, its utilization and maintenance are specifically defined. Events and actions like, for instance, financial transactions or regulatory compliance violations can be evaluated on an automated basis by applying various approaches and methods using the regulatory knowledge system. | 11-04-2010 |
Ewa Hansen, Vasteras SE
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20130057389 | WIRELESS COMMUNICATION BETWEEN TWO TEMPORARILY CONNECTED DEVICES - A system for setting up a wireless connection between two temporarily connected devices includes a device interconnector having a first end provided with a first wireless communication identifier and a second end provided with a second wireless communication identifier, a first device having a first interconnector mating unit, a first wireless communication unit and a first reading unit and a second device having a second interconnector mating unit, a second wireless communication unit and a second reading unit. The wireless communication units of each device is configured to receive an identifier being read by the corresponding reading unit as the device interconnector is attached to the corresponding mating unit and the wireless communication unit is configured to employ this identifier in setting up, together with the other wireless communication unit, a wireless connection between the two devices. | 03-07-2013 |
Ewa Hekstra-Nowacka, Waalre NL
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20080201537 | Memory Controller and Method for Coupling a Network and a Memory - A memory controller (SMC) is provided for coupling a memory (MEM) to a network (N; IM). The memory controller (SMC) comprises a first interface (PI) for connecting the memory controller (SMC) to the network (N; IM). The first interface (PI) is arranged for receiving and transmitting data streams (ST | 08-21-2008 |
20080209064 | System and Method For Transmitting Data - A device (D | 08-28-2008 |
20090083500 | MEMORY CONTROLLER AND METHOD FOR COUPLING A NETWORK AND A MEMORY - A memory controller (SMC) is provided the for coupling a memory (MEM) to a network (N). The network (N) comprises at least one network interface (PCIEI) having network interface buffers (TPB, FCB) for implementing a flow control across the network (N). The memory controller (SMC) comprises a buffer managing unit (BMU) for managing the buffering of data from the network (N) to exchange data with the memory (MEM) in bursts. The buffer managing unit (BMU) furthermore monitors the network interface buffers (TPB, FCB) in order to determine whether sufficient data is present in the network interface buffers (FCB) such that a burst of data can be written to the memory (MEM) and whether sufficient space is available in the network interface buffers (TPB) such that a burst of data from the memory (MEM) can be buffered in the network interface buffers (TPB). The buffer managing unit (BMU) controls the access to the memory (MEM) according to according to the data and/or space in the network interface buffers (FCB, TPB). | 03-26-2009 |
20090172198 | SYSTEM AND METHOD FOR SYNCHRONISING A DATA PROCESSING NETWORK - A data processing system according to the invention comprising a group of at least a first and a second module, wherein each module has a data processing facility, a clock for timing data transmissions from the module to another module, a time-slot counter for counting a number of time slots which are available for transmission of data. The modules have a first operational state wherein the counted number of time slots is less than or equal to a predetermined number, in which operational state data transmission is enabled, and a second operational state wherein the number is in excess of the predetermined number, in which second operational state data transmission is disabled, Each module has a notifying facility for notifying when it is in the second operational state. The data processing system has at least one detecting facility that detects whether the other modules have notified that they are in the second operational state and the modules each have an initialization facility for resetting the time-slot counter when the module is in the second operational state and each of the other modules has notified that it is in the second operational state. | 07-02-2009 |
20090222705 | DATA PROCESSOR SYSTEM AND A METHOD FOR COMMUNICATION DATA - A data processor system is described comprising a first and a second data processor unit (PU | 09-03-2009 |
20100198936 | STREAMING MEMORY CONTROLLER - A memory controller (SMC) is provided for coupling a memory (MEM) to a network (N). The memory controller (SMC) comprises a first interface (PI), a streaming memory unit (SMU) and a second interface (MI). The first interface (PI) is used for connecting the memory controller (SMC) to the network (N) for receiving and transmitting data streams (ST | 08-05-2010 |
Ewa Jablonska, Chynow PL
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20130095108 | FACTOR XII INHIBITORS FOR TREATING INTERSTITIAL LUNG DISEASE - The present invention provides methods for treating interstitial lung diseases, comprising administering to an individual an effective amount of an inhibitor of coagulation factor XII. The invention further provides uses and pharmaceutical kits for that treatment. | 04-18-2013 |
Ewa Karlsson, Bromma SE
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20140275254 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF FUNGAL INFECTIONS - There is provided pharmaceutical compositions suitable for topical application to the nail for the treatment of nail diseases such as onychomycosis, comprising a urea-based component, a diol component, such as propylene glycol, an organic acid component, such as lactic acid, and a triol component, such a glycerol. There is further provided methods of improving the storage stability of a pharmaceutical composition suitable for topical application to the skin and/or nails comprising such urea-based components, diol components, organic acid components, and, optionally, an aqueous base, which method comprises adding a triol component, such a glycerol, to that composition prior to said storage. | 09-18-2014 |
20150306052 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF FUNGAL INFECTIONS - There is provided pharmaceutical compositions suitable for topical application to the nail for the treatment of nail diseases such as onychomycosis, comprising a urea-based component, a diol component, such as propylene glycol, an organic acid component, such as lactic acid, and a triol component, such a glycerol. There is further provided methods of improving the storage stability of a pharmaceutical composition suitable for topical application to the skin and/or nails comprising such urea-based components, diol components, organic acid components, and, optionally, an aqueous base, which method comprises adding a triol component, such a glycerol, to that composition prior to said storage. | 10-29-2015 |
Ewa Kijak, Erce Pres Liffre FR
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20090144608 | Device and method for creating summaries of multimedia documents - The invention relates to a device ( | 06-04-2009 |
Ewa Kijak, Saint Aubin Du Cormier FR
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20130080431 | COMPUTER TOOL WITH SPARSE REPRESENTATION - Computer tool characterised in that it includes: | 03-28-2013 |
20160098421 | COMPUTER TOOL WITH SPARSE REPRESENTATION - Computer tool characterised in that it comprises: | 04-07-2016 |
Ewa Kijak, Dinge FR
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20090034932 | Method for Selecting Parts of an Audiovisual Program and Device Therefor - The invention relates to a method of selecting parts of an audiovisual document. First, the document is analyzed by at least two subdividing means in order to extract from it at least two groups of audiovisual sequences. Then, selection criteria associated with each of the two subdividing means are entered. Finally, a list of sequences responding to all the selection criteria entered previously is generated. | 02-05-2009 |
Ewa Kilar, Swidnica PL
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20100012588 | SYSTEM AND METHOD FOR THE EXTRA-CORPOREAL PURIFICATION OF BLOOD OF PATHOGENIC ENZYMES - The invention concerns an extra-corporeal system and method to purify blood of pathogenic enzymes which initiate tumoral processes as well as evoke dystrophic muscular lesion, including enzymes of the group of cysteine peptidases, in particular of cathepsins B and L and calpain, this system being intended for removing these proteins from the blood in order to eliminate the degradation of the body's cells caused by the presence of these proteins in the blood. | 01-21-2010 |
Ewa Kowalk, Atlanta, GA US
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20100160284 | CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY AND PROCESSES FOR THEIR PREPARATION - The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of β-methyl carbapenems which are useful as antibacterial agents. | 06-24-2010 |
Ewa Kowalska, Krakow PL
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20160060631 | DNA APTAMERS BINDING THE HISTIDINE TAG AND THEIR APPLICATION - A DNA aptamer was obtained which has an affinity for His-tag, and contains a nucleotide sequence selected from SEQ ID No. 1 and SEQ ID No. 2, which has clear applications. | 03-03-2016 |
Ewa Krasnowska, Roma IT
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20140030307 | NEW COMBINATION COMPRISING N-ACETYL-L-CYSTEINE AND ITS USE - A combination of N-acetyl-L-cysteine, selenium in the form of selenomethionine and melatonin, and a medical product or pharmaceutical composition comprising such combination, useful for the treatment of a variety of diseases and conditions is described. The combination of N-acetyl-L-cysteine, selenium in the form of selenomethionine and melatonin is also useful for cosmetic treatment of skin and as an antibacterial agent. | 01-30-2014 |
Ewa Kubalska, Los Gatos, CA US
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20090204834 | SYSTEM AND METHOD FOR USING INPUTS AS WAKE SIGNALS - A system and method for waking up a portion of a programmable system on a chip (SoC). The system includes a power management unit for controlling power levels to the SoC and one or more inputs for receiving inputs from a coupled device. The system further includes a power management interface coupled to the one or more inputs. The power management interface signals the power management unit to adjust power levels to the SoC in response to receiving a signal via the one or more inputs corresponding to a wake event. | 08-13-2009 |
20090256607 | POWERED RING TO MAINTAIN IO INDEPENDENT OF THE CORE OF AN INTEGRATED CIRCUIT DEVICE - In an integrated circuit device, a power circuit for maintaining asserted values on an input output pin of the device when a functional block of the device is placed in a sleep mode. The device includes a power circuit disposed along the periphery of the device, the power circuit configured to maintain power when the device is placed in a low-power mode. A plurality of input output blocks are included in the device and are for receiving external inputs for the integrated circuit device and for providing outputs from the integrated circuit device. The power circuit is coupled to provide power to at least one of the input output blocks to maintain state when the integrated circuit device is in the low-power mode. | 10-15-2009 |
Ewa Lada, Nowa Iwiczna PL
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20130152308 | INTELLIGENT HOSPITAL BED AND METHOD FOR OPERATING SAME - The invention relates to an intelligent hospital bed comprising a lower main frame ( | 06-20-2013 |
Ewa Lesniewska, Lodz PL
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20150283496 | MULTILAYER COMPOSITE FOR REVERSIBLE SORPTION OF MERCURY AND METHOD FOR SORPTION AND DESORPTION OF MERCURY FROM A GASEOUS PHASE - A multilayer composite for reversible sorption of mercury, with a carrier core made of a metal or an alloy based on transition metals, has isolating layers of a transition metal nitride and externally located sorptive layers, made of a mixture of sulfides and nitrides of transition metals, the layers being deposited on both sides of the core. A method for sorption of mercury from a gaseous phase during an exposition of the multilayer composite to the influence of multicomponent gaseous mixtures that contain mercury vapours or compounds for a time period of 0.5 to 24 hours, while the temperature of the multilayer composite is maintained in the range from 20 to 150° C. | 10-08-2015 |
Ewa Lindenstroem, Vaerloese DK
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20110217317 | TREATMENT OF THROMBOCYTOPENIA - The present invention relates to treatment of thrombocytopenia with a pharmaceutical composition comprising re-combinant polyclonal anti-RhesusD antibody product as the active ingredient. | 09-08-2011 |
Ewa Malatynska, Doyletown, PA US
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20080317883 | METHODS FOR TREATING DEPRESSION - The present invention is a method for the treatment of depression comprising administering to a subject in need thereof a therapeutically effective amount of one or more carbamate compounds of Formula 1 and/or Formula 2 as herein defined and shown below for the treatment of depression. | 12-25-2008 |
Ewa Micewicz, Los Angeles, CA US
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20160090369 | RADIOMITIGATING PHARMACEUTICAL FORMULATIONS - The present disclosure relates to compounds of Formula (I) and (II), compositions containing the compounds (alone or in combination with other agents), and their use to prevent, mitigate or treat a) damage induced by ionizing radiation, b) inflammation or c) cancer. | 03-31-2016 |
Ewa Moczko, Srebrna Gora PL
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20100304421 | OPTICAL MONITORING METHOD - A mixture of dyes each having an optical property (e.g. fluorescence intensity) which is sensitive to an external factor is caused to interact with a system that is to be monitored, such that the system provides the external factor and therefore influences the optical properties of the dyes. The optical properties of the individual dyes are individually measurable (e.g. being spectral intensities at different wavelengths). Their values are subjected to pattern analysis, e.g. using an artificial neural network analysis, leading to an output that characterises the system or its state. | 12-02-2010 |
Ewa Oldak, Bethlehem, PA US
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20100056409 | COMPOSITIONS FOR PROCESSING OF SEMICONDUCTOR SUBSTRATES - Compositions useful in microelectronic device manufacturing for surface preparation and/or cleaning of wafer substrates such as microelectronic device precursor structures. The compositions can be employed for processing of wafers that have, or are intended to be further processed to include, copper metallization, e.g., in operations such as surface preparation, pre-plating cleaning, post-etching cleaning, and post-chemical mechanical polishing cleaning of microelectronic device wafers. The compositions contain (i) alkanolamine, (ii) quaternary ammonium hydroxide and (iii) a complexing agent, and are storage-stable, as well as non-darkening and degradation-resistant in exposure to oxygen. | 03-04-2010 |
Ewa Oldak, Fountain Hill, PA US
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20090120457 | COMPOSITIONS AND METHOD FOR REMOVING COATINGS AND PREPARATION OF SURFACES FOR USE IN METAL FINISHING, AND MANUFACTURING OF ELECTRONIC AND MICROELECTRONIC DEVICES - Improved cleaning compositions for removing particles, organic contamination, photoresist, post-ash residue, coatings, and other materials from metal and silicon surfaces including substrates present during the manufacture of integrated circuits, liquid crystal displays, and photovoltaic devices. The cleaning and surface preparation compositions comprise one or more water soluble strongly basic components, one or more water soluble organic amines, one or more water soluble oxidizing agents, balance water. Optional components can include corrosion inhibitors, surfactants and chelating agents. | 05-14-2009 |
20100018550 | CLEANING COMPOSITIONS WITH VERY LOW DIELECTRIC ETCH RATES - Aqueous cleaning compositions comprising a tertiary organic amine, an organic acid, a non-metallic fluoride salt, a corrosion inhibitor, e.g., ascorbic acid or its derivatives alone or in combination, balance water, effective to remove plasma processing residues (sidewall polymer) which include metal-organic complexes and/or inorganic salts, oxides, hydroxides or complexes which form films or residues either alone or in combination with the organic polymer resins. These compositions clean effectively at low temperatures without etching metal or dielectric layers, including low-κ dielectric materials. | 01-28-2010 |
20120187336 | CONDITIONING COMPOSITIONS FOR SOLAR CELLS - Method of using improved compositions for conditioning silicon surfaces during the manufacture of photovoltaic devices. Used for removing particles, organic contamination, and unwanted metals from these surfaces. Also used for removing a thin layer of silicon as required for damage removal or texturing. These conditioning and surface preparation compositions comprise one or more water soluble strongly basic components capable of producing a pH greater than 10, one or more water soluble organic amines, one or more chelating agents, and water. | 07-26-2012 |
Ewa Osika, Cambridge CA
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20120142676 | Oxathiazine and dithiine oxides as inhibitors of sulfhydryl-dependent biomolecules - Novel derivatives of dihydro-1,4,2-oxathiazine and dihydro-1,4-dithiine oxides, more particularly, novel derivatives of dihydro-1,4,2-oxathiazine and dihydro-1,4-dithiine oxides that target cysteine residues of biomolecules of pharmacological importance are provided as pharmaceutically useful compounds, for example, as anticancer, antiinfectious, antigastric acid secretion, antiosteoporosic, and antiinflammatory agents. | 06-07-2012 |
Ewa Owska, Gdansk PL
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20150045316 | SEMISYNTHETIC DERIVATIVES OF NYSTATIN A1 - The invention provides semisynthetic derivatives of Nystatin A | 02-12-2015 |
Ewa Piotrowska, Olsztyn PL
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20090062380 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES - The invention relates to the medical use of natural isoflavones and their semisynthetic derivatives or the pharmaceutically acceptable salts thereof for the therapeutic and/or prophylactic treatment of diseases, at the base of which lies an excessive production or storage of glycosaminoglycans, especially for treatment of mucopolysaccharidoses. The isoflavones and their semisynthetic derivatives are represented by formula (I), in which R | 03-05-2009 |
20120190642 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES - A method of treatment of mucopolysaccharidosis, the method including administering to a patient in the need of such treatment—a therapeutically effective amount of a natural isoflavone of formula (I), a derivative thereof, or a pharmaceutically acceptable salt thereof. A pharmaceutical composition including a pharmaceutically acceptable excipient; and a natural isoflavone of formula (I), a derivative thereof, or a pharmaceutically acceptable salt thereof, the natural isoflavone, the derivative thereof, or the pharmaceutically acceptable salt thereof being in a therapeutically effective amount for the treatment of mucopolysaccharidosis. | 07-26-2012 |
20140107051 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES - A pharmaceutical composition including a pharmaceutically acceptable excipient; and a natural isoflavone of formula (I), a derivative thereof, or a pharmaceutically acceptable salt thereof, the natural isoflavone, the derivative thereof, or the pharmaceutically acceptable salt thereof being in a therapeutically effective amount for the treatment of mucopolysaccharidosis. A method of treatment of mucopolysaccharidosis, the method including administering to a patient in the need of such treatment—a therapeutically effective amount of a natural isoflavone of formula (I), a derivative thereof, or a pharmaceutically acceptable salt thereof. | 04-17-2014 |
Ewa Prokopczuk, Danville, CA US
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20090312340 | USE OF RANOLAZINE FOR THE TREATMENT OF CARDIOVASCULAR DISEASES - Disclosed are methods for treating patients suffering from cardiovascular diseases comprising administering an intravenous (IV) infusion of ranolazine. In one embodiment, the IV infusion of ranolazine is followed by an orally administered sustained release ranolazine dosage formulation to maintain human ranolazine plasma levels at therapeutic levels in patients. | 12-17-2009 |
20150283149 | METHODS OF TREATING PATIENTS HAVING IMPLANTABLE CARDIAC DEVICES - Described herein are methods for reducing ventricular tachycardia/ventricular fibrillation (VT/VF), methods for reducing implantable cardioverter-defibrillator device (ICD) shocks, methods for reducing CV hospitalization, ER visits, CV death or SCD in patients having implantable cardiac devices or CRT, and methods for reducing the use of ICD in a human patient without prior VT/VF, by administering an effective amount of the potent and selective late sodium ion channel blocker Compound 1. | 10-08-2015 |
Ewa Rucinska, Goteborg SE
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20110315576 | PACKAGE OF TISSUES - A package of tissues or napkins includes a stack of tissues or napkins and a wrapping sheet. The wrapping sheet extends over at least a first pair of side surfaces, a lower end surface, and at least a portion of an upper end surface of the stack. A first sheet end of the wrapping sheet is provided with a first releasable attachment arrangement for attaching the first sheet end to a first wall of a container accommodating the package of tissues or napkins, and a second sheet end is adapted for being attached to an opposing second wall of the container such that the wrapping sheet holds the stack of tissues or napkins with the upper end surface exposed. The stack of tissues or napkins is easily accessible and may be repositioned in the container. | 12-29-2011 |
Ewa Skrzypczak-Jankun, Sylvania, OH US
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20100137209 | MODIFIED PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 AND METHODS BASED THEREON - The present invention is based upon the discovery that modified plasminogen activator inhibitor type-I (PAI-1) in which two or more amino acid residues that do not contain a sulfhydryl group have been replaced with amino acid residues that contain a sulfhydryl group and, therefore, forms intramolecular disulfide bonds, have increased in vivo half-life. Also disclosed are the modified PAI-1 proteins, derivatives and analogs thereof, specific antibodies, nucleic acid molecules and host cells. Methods for producing modified PAI-1, derivatives and analogs are also provided. The invention further relates to Therapeutics, pharmaceutical compositions and method of using the composition for treatment. The invention may be used to inhibit angiogenesis in a subject, thereby treating diseases or conditions associated with undesired angiogenesis and cell proliferation. Such conditions include psoriasis, chronic inflammation, tumor invasion and metastasis and conditions in which angiogenesis is pathogenic. The modified PAI-1 molecules of the present invention are useful for the treatment, prophylaxis, management and amelioration of cardiovascular diseases such as, but not limited to those that are related to hyperfibrinolysis, hemophilia, and vessel leakage syndrome. | 06-03-2010 |
20100184667 | MODIFIED PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 MOLECULE AND METHODS BASED THEREON - The present invention relates to a modified plasminogen activator inhibitor type-1 (PAI-1) molecule that displays CN an increased in vivo half-life of the active form of PAI-1, but is deficient in one or more functional activities as compared to the wild-type PAI-1 protein. The modified PAI-1 molecule that displays an increased half-life further displays at least one of the following funtional characteristics: (i) decreased binding activity to at least one of the following molecules: urokinase plasminogen activator (uPA), tissue plasminogen activator (tPA) and vitronectin (Vn); and (ii) decreased specific activity against at least one of the following molecules: uPA, tPA and Vn. The invention further relates to pharmaceutical compositions comprising modified PAI-1 molecules and methods of using these pharmaceutical compositions for treatment. | 07-22-2010 |
Ewa Smigiera, Warszawa PL
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20150291891 | A METHOD OF OBTAINING PARAFFINIC HYDROCARBONS FROM NATURAL FAT - A method of obtaining paraffinic hydrocarbons from fat, by an exemplary method, whereby the method is performed in two stages, in a coupled flow-type system, under atmospheric pressure conditions, in the presence of heterogeneous catalysts, after their thermal activation, so that in Stage I the fat and/or waste fat is heated at a temperature range of 100-500° C., in the presence of an inert gas, in the presence of a catalyst in the form of a metal oxide on an oxide support or in the form of a mixture of at least two metal oxides on an oxide support. The product obtained in Stage I is treated, in the presence of an inert gas, at a temperature range of 100-500° C., in the presence of a metallic catalyst on an oxide support, with hydrogen gas or with a mixture of hydrogen and carbon monoxide, obtained in the selective decomposition of methanol. | 10-15-2015 |
Ewa Szajna- Fuller, Ames, IA US
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20130251865 | Antioxidant Formulations - Antioxidant formulations containing new active molecules with tocopherols are disclosed. The best performing formulas contain extracts of green tea that are oil soluble, extracts of rosemary, extracts of spearmint and tocotrienols. Interestingly, the amount of tocopherols in formulas could be reduced by 50% in this diet when the other actives were increased accordingly. | 09-26-2013 |
Ewa Szolajska, Warszawa PL
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20120141425 | VIRUS-LIKE PARTICLE VECTOR FOR DELIVERY OF PHARMACEUTICAL AGENTS, A PROCESS FOR THE MANUFACTURE THEREOF, ITS USES AND A PHARMACEUTICAL COMPOSITION - The embodiment of the invention is a virus-like particle vector, a process for the manufacture thereof, use of the virus-like particle vector and a pharmaceutical composition, which contains the virus-like particle vector. The vector is intended for the delivery of therapeutic agents into specific mammalian tissues, especially low molecular weight agents, in particular low molecular weight anti-cancer drugs into cancer tissues. More specifically, the invention relates to the virus-like particle vector, which constitutes an adenoviral dodecahedron with the therapeutic substance encapsulated or covalently linked. | 06-07-2012 |
Ewa Urbanczyk-Wochniak, Golm DE
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20080288174 | Method for Identifying the Function of a Gene - Described is a method for determining the function of a gene. This method involves determining the amount of transcript for each of a set of candidate genes in samples taken from different phenotypic and/or genotypic states of an organism and determining the amount of each of a plurality of metabolites in different samples taken from the same states as those mentioned above. Subsequently, the data obtained is analyzed by suitable mathematical methods in order to identify a transcript and metabolites which correlate in the different states, thereby identifying a transcript corresponding to a gene which influences the amount of metabolites in the organism. Furthermore described is a method for identifying a gene which is capable of modifying the amount of a metabolite in an organism and to a method for identifying a metabolite which is capable of modifying the amount of a transcript in an organism. Likewise, uses of the genes and metabolites identified in the aforementioned methods are described. | 11-20-2008 |
Ewa Wandzioch, Wyndmoor, PA US
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20140323546 | PME-1 AS A BIOMARKER TO PREDICT AND DIAGNOSE AN INCREASED RISK OF ENDOMETRIAL CANCER AND GENE SILENCING OF PME-1 TO INHIBIT EPITHELIAL TO MESENCHYMAL TRANSITION - Disclosed are methods of attenuating activity of the PME-1 gene. siRNAs or shRNAs are used to target against PME-1, thereby reducing the PME-1 mRNA. It is disclosed that the siRNAs or shRNAs targeted against PME-1 attenuate the epithelial to mesenchymal transition, thereby inhibit endometrial cancer development. A kit containing siRNA or shRNA reagents for attenuating the PME-1 gene expression is also disclosed. | 10-30-2014 |
Ewa Wasilewska, Swedow PL
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20100137576 | 5' O [(N ACYL)AMIDOPHOSPHATE] AND 5' O [(N ACYL)AMIDOTHIOPHOSPHATE] AND 5' O [(N ACYL)AMIDODITHIOPHOSPHATE] AND 5' O [(N ACYL)AMIDOSELENOPHOSPHATE] DERIVATIVES OF NUCLEOSIDES AND PROCESSES FOR THE MANUFACTURE THEREOF - The subject of the invention includes 5′-O-[(N-acyl)amidophosphate]- and 5′-O-[(N-acyl)amidothiophosphate]- and 5′-O-[(N-acyl)amidodithiophosphate]- and 5′-O-[(N-acyl)amidoselenophosphate]- derivatives of nucleosides. | 06-03-2010 |
Ewa Zuziak, Brzeg Dolny PL
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20110008873 | PURIFIED BACTERIOPHAGE, ITS PREPARATION AND APPLICATION - A method of preparation of purified bacteriophage with increased antibacterial activity, in which from bacterial lysate of phages is obtained, advantageously in the presence of lysozyme, chelating factor and detergent, in a continuous manner with ultrafiltration on membranes, the phage containing high molecular mass preparation, devoid of bacterial cell wall and other contaminants, free of toxins and endotoxins, active in tests of bacterial lysis, which is characterized by chromatography HPLC, In SDS-PAGE electrophoresis, immunoblotting, biological tests of bacterial lysis, and is dedicated for phage therapy of bacterial infections and tumors and for production of phage deriving pharmaceutical preparations. | 01-13-2011 |
Ewa Zuziak, Wroclaw PL
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20110256103 | METHOD OF PRODUCING A PHARMACOLOGICALLY STABLE FORM OF LYOPHILISED, ACTIVE PREPARATIONS OF PURIFIED BACTERIOPHAGES - The subject the present invention is a method of producing a pharmacologically stable form of purified and lyophilised bacteriophage preparations of increased stability and antibacterial activity, characterised in that phages produced from a bacterial lysate, for example by ultrafiltration on ultrafiltration membranes, containing a high molecular weight preparation of purified phages is stabilised most preferably with a probiotic extract in the presence or absence of neutral salts and/or organic solvents, lyophilised, characterised via HPLC chromatography, by SDS-PAGE, and bacterial lysis biological assays, and then stored under a vacuum, where the active lyophilisate is destined for phage therapy of infections and tumours. | 10-20-2011 |