Emily S.
Emily S. Hsu, Munich DE
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20120122889 | SMALL MOLECULE INHIBITORS OF NECROPTOSIS - The invention features a series of heterocyclic derivatives that inhibit tumor necrosis factor alpha (TNF-α) induced necroptosis. The heterocyclic compounds of the invention are described by Formulas (I)-(VIII) and by Compounds (I)-(I), (13)-(26), (27)-(33), (48)-(57), and (58)-(70). These necrostatins are shown to inhibit TNF-α induced necroptosis in FADD-deficient variant of human Jurkat T cells. The invention further features pharmaceutical compositions featuring necrostatins. The compounds and compositions of the invention may also be used to treat disorders where necroptosis is likely to play a substantial role. | 05-17-2012 |
20140024657 | SMALL MOLECULE INHIBITORS OF NECROPTOSIS - The invention features a series of heterocyclic derivatives that inhibit tumor necrosis factor alpha (TNF-α) induced necroptosis. The heterocyclic compounds of the invention are described by Formulas (I)-(VIII) and by Compounds (1)-(7), (13)-(26), (27)-(33), (48)-(57), and (58)-(70). These necrostatins are shown to inhibit TNF-α induced necroptosis in FADD-deficient variant of human Jurkat T cells. The invention further features pharmaceutical compositions featuring necrostatins. The compounds and compositions of the invention may also be used to treat disorders where necroptosis is likely to play a substantial role. | 01-23-2014 |
Emily S. Kociolek, Westmont, IL US
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20160113301 | NON-POROUS WEIGHTS FOR USE IN FERMENTING VESSELS - An improved weight for use in fermenting vessels (e.g., glazed ceramic fermenting crocks) comprises a multi-sectioned weight made from a non-porous material. The non-porous material is preferably glass, and the glass is preferably non-leaded. In one embodiment, a number of sections of the multi-sectioned weight is 2, and in another embodiment, the number of sections is 4. Use of non-porous material renders the weight impenetrable by the fermenting liquid, and also by mold, harmful bacteria, and/or foul smells that may occur if something goes wrong during the fermentation process. | 04-28-2016 |
Emily S. Winn-Deen, Potomac, MD US
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20110003281 | Device and method for multiple analyte detection - The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device. | 01-06-2011 |
20110022555 | Computer Algorithm for Automatic Allele Determination from Fluorometer Genotyping Device - The present invention provides methods and systems for an automated method of identifying allele values from data files derived from processed fluorophore emissions detected during the observation of fluorophore labeled nucleotide probes used in analyzing polymorphic DNA are provided. These methods are used in the rapid and efficient distinguishing of targeted polymorphic DNA sites without control samples. | 01-27-2011 |
Emily S. Winn-Deen, Livermore, CA US
Patent application number | Description | Published |
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20120143872 | Computer Algorithm for Automatic Allele Determination from Fluorometer Genotyping Device - The present invention provides methods and systems for an automated method of identifying allele values from data files derived from processed fluorophore emissions detected during the observation of fluorophore labeled nucleotide probes used in analyzing polymorphic DNA are provided. These methods are used in the rapid and efficient distinguishing of targeted polymorphic DNA sites without control samples. | 06-07-2012 |
20120303472 | METHODS FOR PLACING, ACCEPTING, AND FILLING ORDERS FOR PRODUCTS AND SERVICES - Methods and systems for ordering assays which detect SNPs or gene expression are provided. The methods use PCR and RT-PCR procedures. Collections of stock assays are assembled using pre- and post-manufacturing quality control procedures and made available to consumers via the Internet. In addition, custom assays are prepared upon order from the consumer and these assays are also prepared using pre- and post-manufacturing quality control procedures. The assays are then delivered to the consumer. | 11-29-2012 |
20140108411 | Computer Algorithm for Automatic Allele Determination from Fluorometer Genotyping Device - The present invention provides methods and systems for an automated method of identifying allele values from data files derived from processed fluorophore emissions detected during the observation of fluorophore labeled nucleotide probes used in analyzing polymorphic DNA are provided. These methods are used in the rapid and efficient distinguishing of targeted polymorphic DNA sites without control samples. | 04-17-2014 |