Patent application number | Description | Published |
20090259303 | Tool for Implantation of Replacement Heart Valve - An implant holder for removably retaining an implant during an implantation procedure includes a holder device having a frame defining a chamber. The frame may be configured for removable retention of an implant, such as the flexible bioprosthetic heart valve, substantially within the chamber. The removable retention of the implant to the implant holder maintains the implant in an orientation and shape suitable for implantation. | 10-15-2009 |
20100100176 | ANCHORING STRUCTURE WITH CONCAVE LANDING ZONE - A method and device for reducing paravalvular leakage upon implantation of a replacement heart valve is provided. The valve assembly includes a tissue or bioprosthetic heart valve attached to an anchoring structure. The anchoring structure includes an inlet rim that is substantially C-shaped in cross section to form a concave landing zone. The anchoring structure self-seats when implanted in the sinus of a patient with the proximal and distal ends of the C-shaped inlet rim pushed against the aorta to effectively prevent paravalvular leakage. | 04-22-2010 |
20100168844 | METHODS AND SYSTEMS FOR REDUCING PARAVALVULAR LEAKAGE IN HEART VALVES - A replacement valve comprises a valve body having an inflow end, an outflow end, and a valve support structure, and a valve cuff surrounding the inflow end of the valve body. The valve support structure surrounds the valve body, and the valve cuff is coupled to the valve support structure. The valve cuff includes a skirt portion and at least one flange coupled to and protruding from the skirt portion, the at least one flange forming a seal around the inflow end of the valve body. | 07-01-2010 |
20110060404 | SURGICAL DELIVERY DEVICE AND METHOD OF USE - A delivery device for a stented heart valve comprises a handle, an elongate shaft extending from a distal end of the handle, and a conical housing having a proximal end coupled to the elongate shaft and an open distal end, the conical housing having a conical lumen therein with a first internal diameter adjacent to the proximal end of the conical housing and a larger second internal diameter adjacent to the open distal end of the conical housing. | 03-10-2011 |
20110106246 | TRANSAPICAL DELIVERY DEVICE AND METHOD OF USE - A delivery device for a stented heart valve comprises a handle, an inner catheter shaft extending from the handle and having an enlarged bumper element at a distal end, an outer catheter shaft extending from the handle and slidably coupled around the inner catheter shaft, and a retraction mechanism for controlling longitudinal movement of the outer catheter shaft relative to the inner catheter shaft. The outer catheter shaft includes a generally cylindrical housing at a distal end that is structured to receive the bumper element therein. | 05-05-2011 |
20120239129 | TWISTING BIFURCATION DELIVERY SYSTEM - A catheter system comprises a catheter having an elongate catheter shaft such that a portion of the catheter shaft proximal a stent retaining region defines at least one bend that is bent around the longitudinal axis of a vessel. The catheter also has a side branch guidewire housing, defining a side branch guidewire lumen, and a side branch guidewire that extends through the side branch guidewire lumen. | 09-20-2012 |
Patent application number | Description | Published |
20090186348 | MICRORNAS DIFFERENTIALLY EXPRESSED IN CERVICAL CANCER AND USES THEREOF - The present invention concerns methods and compositions for identifying a miRNA profile for a particular condition, such as cervical disease, and using the profile in assessing the condition of a patient. | 07-23-2009 |
20090263803 | MIRNAS DIFFERENTIALLY EXPRESSED IN LYMPH NODES FROM CANCER PATIENTS - The present invention provides diagnostics and/or prognostic methods by identifying miRNAs that are differentially expressed or mis-regulated in various states of diseased, normal, cancerous, and/or abnormal tissues, including but not limited to cervix, skin, colon, breast, bladder, esophagus, liver, ovary, prostate, lung, pancreas, thyroid, kidney, stomach, testicle, uterus, spleen, tongue, brain, thymus, trachea and/or small intestine. In certain apsects, differential miRNA expression is initially determined by comparing miRNA expression between a normal tissue and cancer negative lymph node (LNneg), a normal tissue and a cancer positive lymph node (LNpos), a cancerous tissue and LNneg and/or LNpos, LNneg and LNpos. The methods of the invention are used to identify the presence or absence of non-lymphoid cells from other organs or tissues, and/or metastatic cancer cells present in lymph nodes. | 10-22-2009 |
20130184175 | MICRORNAS DIFFERENTIALLY EXPRESSED IN CERVICAL CANCER AND USES THEREOF - The present invention concerns methods and compositions for identifying a miRNA profile for a particular condition, such as cervical disease, and using the profile in assessing the condition of a patient. | 07-18-2013 |
20140141423 | miRNAs Differentially Expressed in Lymph Nodes from Cancer Patients - The present invention provides diagnostics and/or prognostic methods by identifying miRNAs that are differentially expressed or mis-regulated in various states of diseased, normal, cancerous, and/or abnormal tissues, including but not limited to cervix, skin, colon, breast, bladder, esophagus, liver, ovary, prostate, lung, pancreas, thyroid, kidney, stomach, testicle, uterus, spleen, tongue, brain, thymus, trachea and/or small intestine. In certain aspects, differential miRNA expression is initially determined by comparing miRNA expression between a normal tissue and cancer negative lymph node (LNneg), a normal tissue and a cancer positive lymph node (LNpos), a cancerous tissue and LNneg and/or LNpos, LNneg and LNpos. The methods of the invention are used to identify the presence or absence of non-lymphoid cells from other organs or tissues, and/or metastatic cancer cells present in lymph nodes. | 05-22-2014 |
Patent application number | Description | Published |
20100031867 | INTERCHANGEABLE SUPERSTRUCTURES AND HULLS FOR OCEAN GOING VESSELS - An ocean going vessel with interchangeable superstructure and hull in which the superstructure has control units for controlling propulsion and steering, as well as components for communication and navigation. The superstructure and the hull each have an interface providing quick connect and disconnect capability between the control units of the superstructure and the components being controlled of the hull. A system for interchanging superstructures and hulls for ocean going vessels is enabled in which the superstructure of an inbound vessel is removed and transferred to an outbound hull with the use of a crane at the port facility. This facilitates quick turnaround time of the superstructure and crew of the inbound vessel. This also enables inbound ship hulls to be inspected without delaying the outbound hull that has been preloaded from being shipped out of port with the transferred superstructure. | 02-11-2010 |
20110126755 | INTERCHANGABLE SUPERSTRUCTURES AND HULLS FOR OCEAN GOING VESSELS - An ocean going vessel with interchangeable superstructure and hull in which the superstructure has control units for controlling propulsion and steering, as well as components for communication and navigation. The superstructure and the hull each have an interface providing quick connect and disconnect capability between the control units of the superstructure and the components being controlled of the hull. A system for interchanging superstructures and hulls for ocean going vessels is enabled in which the superstructure of an inbound vessel is removed and transferred to an outbound hull with the use of a crane at the port facility. This facilitates quick turnaround time of the superstructure and crew of the inbound vessel. This also enables inbound ship hulls to be inspected without delaying the outbound hull that has been preloaded from being shipped out of port with the transferred superstructure. | 06-02-2011 |
20120285363 | INTERCHANGEABLE SUPERSTRUCTURES AND HULLS FOR OCEAN GOING VESSELS - An ocean going vessel with interchangeable superstructure and hull in which the superstructure has control units for controlling propulsion and steering, as well as components for communication and navigation. The superstructure and the hull each have an interface providing quick connect and disconnect capability between the control units of the superstructure and the components being controlled of the hull. A system for interchanging superstructures and hulls for ocean going vessels is enabled in which the superstructure of an inbound vessel is removed and transferred to an outbound hull with the use of a crane at the port facility. This facilitates quick turnaround time of the superstructure and crew of the inbound vessel. This also enables inbound ship hulls to be inspected without delaying the outbound hull that has been preloaded from being shipped out of port with the transferred superstructure. | 11-15-2012 |
20140202373 | INTERCHANGEABLE SUPERSTRUCTURES AND HULLS FOR OCEAN GOING VESSELS - An ocean going vessel with interchangeable superstructure and hull in which the superstructure has control units for controlling propulsion and steering, as well as components for communication and navigation. The superstructure and the hull each have an interface providing quick connect and disconnect capability between the control units of the superstructure and the components being controlled of the hull. A system for interchanging superstructures and hulls for ocean going vessels is enabled in which the superstructure of an inbound vessel is removed and transferred to an outbound hull with the use of a crane at the port facility. This facilitates quick turnaround time of the superstructure and crew of the inbound vessel. This also enables inbound ship hulls to be inspected without delaying the outbound hull that has been preloaded from being shipped out of port with the transferred superstructure. | 07-24-2014 |