Dupraz

Ingrid Dupraz, Rietheim/weilheim DE

Patent application number	Description	Published
20130079676	NON-INVASIVE METHOD AND DEVICE FOR DETERMINING A REFERENCE PLANE OF THE HUMAN PELVIS - A non-invasive method for the determination of a reference plane of the human pelvis is described in which method position coordinates of three points A, B, C of the reference plane are determined non-invasively in a reference coordinate system and the reference plane is calculated from the position coordinates of the three points A, B, C, wherein position coordinates of a first point A of the reference plane are determined non-invasively by detecting a first characteristic point (A) on the pelvis, which first characteristic point (A) is located on the reference plane. Furthermore, a device for non-invasively determining a reference plane of the human pelvis is also described.	03-28-2013

Jean-Luc Dupraz, Eschandens CH

Patent application number	Description	Published
20120206359	POINTING DEVICE WITH SOLID-STATE ROLLER - A solid-state roller on a pointing device with enhanced features. The solid-state design described herein allows the sensor to be placed on any shape of surface, such as one that has curvature in two directions. In one embodiment, a trench or downward curve contains sensors for detecting finger movement. The user's finger can thus bend about a knuckle in a curved motion to activate the sensor, requiring little or no movement of the finger up and down. The solid-state sensors can be of one of a number of designs. In one embodiment, multiple electrodes are contacted by a finger as it moves. Each electrode is coupled to a capacitive detection circuit, for detecting the change in capacitance as the electrode is contacted by the finger.	08-16-2012
20130215033	POINTING DEVICE WITH SOLID-STATE ROLLER - A solid-state roller on a pointing device with enhanced features. The solid-state design described herein allows the sensor to be placed on any shape of surface, such as one that has curvature in two directions. In one embodiment, a trench or downward curve contains sensors for detecting finger movement. The user's finger can thus bend about a knuckle in a curved motion to activate the sensor, requiring little or no movement of the finger up and down. The solid-state sensors can be of one of a number of designs. In one embodiment, multiple electrodes are contacted by a finger as it moves. Each electrode is coupled to a capacitive detection circuit, for detecting the change in capacitance as the electrode is contacted by the finger.	08-22-2013

Jean-Pierre Dupraz, Bressolles FR

Patent application number	Description	Published
20110005906	APPARATUS FOR CONTROLLILNG ELECTRICAL SWITCHGEAR - A control apparatus for controlling electrical switchgear, the control apparatus being designed such that it is capable of performing the following in succession:	01-13-2011
20130299320	Electrical Equipment Comprising A Mobile Part Having Improved Dynamics - A locked state for a movable part (	11-14-2013
20130299321	Switchgear for a Vacuum Circuit Breaker Comprising Locking Means - The movable portion (	11-14-2013
20140340182	Electromagnetic Actuator Comprising Permanent Magnets and Mechanical Load Interrupter Actuated By Such An Actuator - The invention relates to a novel permanent magnet electromagnetic actuator with triggering speed and drive torque improved relative to those of the prior art. The main target application is actuating an electromechanical switch-disconnector specifically for performing the operations to disconnect a mechatronic circuit-breaker for breaking high-voltage direct currents.	11-20-2014
20140347101	OPTIMAL HVDC BY-PASS POINT-ON-WAVE INDUCTIVE LOAD SWITCHING - The invention relates to a method of opening a shunt switch carrying a current, the switch being connected in parallel with at least one thyristor of a high voltage DC network, interruption of the current flowing through the switch being initiated at the time of a current zero of the current flowing through the switch, the method being characterized in that it includes, based on a measurement effected by means for measuring the current flowing through the switch, a step of adjusting a control angle of the thyristor to position the current zero in a zone in which the time derivative of the measured current is a continuous function and the absolute value of a peak value of the measured current is substantially equal to the absolute value of the inaccuracy of the measurement of the current zero.	11-27-2014

Michel Louis Dupraz, Morzine FR

Patent application number	Description	Published
20090277203	DEVICE FOR HEATING, COOLING AND PRODUCING DOMESTIC HOT WATER USING A HEAT PUMP AND LOW-TEMPERATURE HEAT STORE - A heating device includes a low-temperature heat store thermally coupled to a heat pump. The heat store is a buried pocket containing a permeable material and water. A high heat exchange capacity is thus achieved by exploiting both the high specific heat of the water and the high latent heat of liquefaction of the water contained in the heat store.	11-12-2009

Philippe Dupraz, Crissier CH

Patent application number	Description	Published
20080286824	System for Screening Cells for High Expression of a Protein of Interest (Poi) - This invention refers to industrial production of proteins. More particularly, the invention refers to a fusion protein as a novel chimeric selection marker comprising a peptide conferring resistance to an antibiotic, or a fragment, allelic variant, splice variant or mutein thereof, and at least one sequence comprising SEQ ID NO: 1, 2 or 3, preferably for producing a protein of interest (POI). The inventive chimeric selection marker exhibits: (i) a resistance to an antibiotic; and (ii) a fluorescence activity upon binding of a ligand to the sequence comprising SEQ ID NO: 1, 2 or 3. The invention further refers to nucleic acids encoding the inventive fusion protein and to expression vectors, comprising the inventive fusion protein and additionally the protein of interest (POI). Finally, uses of the inventive chimeric selection marker for screening cells for high expression of a protein of interest (POI) are disclosed.	11-20-2008
20100167298	PURO-DHFR Quadrifunctional Marker and its use in Protein Production - This invention relates to industrial production of proteins. More specifically, the invention relates to the res-DHFR surrogate marker, which corresponds to a fusion between DHFR and a protein conferring resistance to a toxic compound or conferring a metabolic advantage. The invention further relates to the use of res-DHFR for screening cells for high expression of a protein of interest. The invention is illustrated by the Puro-DHFR surrogate marker, which corresponds to a fusion between the puromycin N-acetyltransferase and dihydrofolate reductase (DHFR).	07-01-2010
20110091901	Vectors and Methods for Screening Cells for High Expression of Protein of Interest (POI) - This invention refers to industrial production of proteins. More particularly, the invention refers to a fusion protein as a novel chimeric selection marker comprising a peptide conferring resistance to an antibiotic, or a fragment, allelic variant, splice variant or mutein thereof, and at least one sequence comprising SEQ ID NO: 1, 2 or 3, preferably for producing a protein of interest (POI). The inventive chimeric selection marker exhibits: (i) a resistance to an antibiotic; and (ii) a fluorescence activity upon binding of a ligand to the sequence comprising SEQ ID NO: 1, 2 or 3. The invention further refers to nucleic acids encoding the inventive fusion protein and to expression vectors, comprising the inventive fusion protein and additionally the protein of interest (POI). Finally, uses of the inventive chimeric selection marker for screening cells for high expression of a protein of interest (POI) are disclosed.	04-21-2011
20130171714	PURO-DHFR QUADRIFUNCTIONAL MARKER AND ITS USE IN PROTEIN PRODUCTION - This invention relates to industrial production of proteins. More specifically, the invention relates to the res-DHFR surrogate marker, which corresponds to a fusion between DHFR and a protein conferring resistance to a toxic compound or conferring a metabolic advantage. The invention further relates to the use of res-DHFR for screening cells for high expression of a protein of interest. The invention is illustrated by the Puro-DHFR surrogate marker, which corresponds to a fusion between the puromycin N-acetyltransferase and dihydrofolate reductase (DHFR).	07-04-2013
20150024485	PURO-DHFR QUADRIFUNCTIONAL MARKER AND ITS USE IN PROTEIN PRODUCTION - This invention relates to industrial production of proteins. More specifically, the invention relates to the res-DHFR surrogate marker, which corresponds to a fusion between DHFR and a protein conferring resistance to a toxic compound or conferring a metabolic advantage. The invention further relates to the use of res-DHFR for screening cells for high expression of a protein of interest. The invention is illustrated by the Puro-DHFR surrogate marker, which corresponds to a fusion between the puromycin N-acetyltransferase and dihydrofolate reductase (DHFR).	01-22-2015

Philippe Dupraz, Crissier (vaud) CH

Patent application number	Description	Published
20140178965	TRANSIENTLY IMMORTALIZED CELLS FOR USE IN GENE THERAPY - The invention provides methods and compositions for expanding cells that are not abundant or are difficult to obtain in pure form in culture, are in short supply (e.g., human cells), or have brief lifetimes in culture, using fusion polypeptide. The fusion polypeptide has a first region having the transport function of herpesviral VP22 protein or human immunodeficiency virus (HIV) TAT protein, and a second region with a polypeptide having cell immortalization activity, a polypeptide having telomerase-specific activity, or a polypeptide having telomerase gene activation activity. The resulting cells of the invention are suitable for use in cell therapy.	06-26-2014

Philippe V. Dupraz, Crissier CH

Patent application number	Description	Published
20150196577	Compounds, Compositions and Methods for Protecting Brain Health in Neurodegenerative Disorders - Aspects of the invention relate to compounds, extracts and compositions thereof, and methods of using of the same, to treat neurodegenerative disorders and/or improve brain health. In certain embodiments, said compounds are pomegranate flavonoids.	07-16-2015

Philippe V. L. Dupraz, Crissier CH

Patent application number	Description	Published
20110065662	Compounds, Compositions, and Methods for Protecting Brain Health in Neurodegenerative Disorders - Aspects of the invention relate to compounds, extracts and compositions thereof, and methods of using of the same, to treat neurodegenerative disorders and/or improve brain health. In certain embodiments, said compounds are pomegranate flavonoids.	03-17-2011