Patent application number | Description | Published |
20090317439 | Cell Preparations for Extemporaneous Use, Useful for Healing and Rejuvenation In Vivo - The present invention relates to new plasma or new platelet-rich plasma preparations, new cell dissociation methods, new cell associations or compositions, a method of preparation thereof, a use thereof, devices for the preparation thereof and preparations containing such a platelet-rich plasma preparation and cell associations or compositions. Specifically, the invention provides compositions comprising plasma or platelet-rich plasma alone or in combination with cell preparations for use in tissue regeneration and bone regeneration and pain reduction. | 12-24-2009 |
20140010857 | Cell Preparations For Extemporaneous Use, Useful for Healing and Rejuvenation In Vivo - The present invention relates to new plasma or new platelet-rich plasma preparations, new cell dissociation methods, new cell associations or compositions, a method of preparation thereof, a use thereof, devices for the preparation thereof and preparations containing such a platelet-rich plasma preparation and cell associations or compositions. Specifically, the invention provides plasma or platelet-rich plasma alone or in cell combinasons preparations for use in tissue regeneration and bone regeneration and pain reduction. | 01-09-2014 |
Patent application number | Description | Published |
20140037574 | PHARMACEUTICAL COMPOSITION - The invention provides a pharmaceutical composition for oral administration of a pharmaceutically active agent to a subject, including the pharmaceutically active agent and an inhibitor of CYP3A4. Administration of the inhibitor and the pharmaceutically active agent reduces pre-systemic degradation of the pharmaceutically active agent by CYP3A4. The inhibitor can be poly(ethylene glycol), methoxy poly(ethylene glycol), aminated poly(ethylene glycol), O-(2-aminoethyl)-O-methoxy poly(ethylene glycol), polyoxyethylene glycol, branched poly(ethylene glycol), 3-arm poly(ethylene glycol), 4-arm poly(ethylene glycol), 8-arm-poly(ethylene glycol)polyamine, poly(L-lysine), poly(L-arginine), poly(L-alanine), poly(L-valine), poly(L-serine), poly(L-histidine), poly(L-isoleucine), poly(L-leucine), poly(L-glutamic acid), poly(L-glutamine), poly(L-guanidine), poly(methyl methacrylate), polyvinyl acetate, polyacrylate, poly(lactic-co-glycolic acid) and derivatives thereof. A method of treatment is also described. | 02-06-2014 |
Patent application number | Description | Published |
20130337022 | PHARMACEUTICAL DOSAGE FORM - A pH responsive and mucoadhesive pharmaceutical dosage form for the release of a pharmaceutically active agent is described. The dosage form includes a mucoadhesive layer for site-specific mucoadhesion, a water-insoluble outer layer, and an intermediate layer including one or more pharmaceutically active agents for site-specific delivery. The different membranous layers perform different functions in order to create a drug delivery system which is able to deliver a drug to a specific site, for a particular period of time and with a specific drug release pattern. The dosage form can have two or more intermediate layers, each layer comprising an active agent. The mucoadhesive layer can also include an active agents. The dosage form is preferably an oral or buccal delivery form for release of the active agent into the gastro intestinal tract. The intermediate layer can be an electrospun fibrous membrane layer containing the active agent. | 12-19-2013 |
20130338569 | POLYMERIC HYDROGEL COMPOSITIONS WHICH RELEASE ACTIVE AGENTS IN RESPONSE TO ELECTRICAL STIMULUS - A polymeric hydrogel composition is described for the delivery of a pharmaceutically active agent when an electrical stimulus is applied to the composition. The composition comprises a polymer which forms the hydrogel, such as poly vinyl alcohol (PVA) cross-linked with diethyl acetamidomalonate (DAA), an electroactive polymer such as polyaniline and a pharmaceutically active agent such as an analgesic, and in particular, indomethacin. The composition can be subcutaneously implanted at a targeted site and under normal conditions, the active agent will be entrapped in the hydrogel itself. However, upon the application of an electric current to the hydrogel, the active agent will be released. When the electric current is removed, the change is reversed and the active agent will cease to be released. In one embodiment of the invention, the hydrogel composition is for use in alleviating chronic pain. | 12-19-2013 |
20130344125 | DRUG DELIVERY DEVICE - The invention provides an implantable intracranial device for the site-specific delivery of a pharmaceutically active agent to a human or animal for treating a mental or neurological disorder, such as Alzheimer's disease, schizophrenia or other psychoses. The biodegradable device includes a pharmaceutically active agent for treating the disorder, polymeric nano-lipoparticles into or onto which the pharmaceutically active agent is embedded; and a polymeric matrix or scaffold incorporating the nano-lipoparticles. The nano-lipoparticles can be in the form of nano-liposhells or nano-lipobubbles. The nano-liposhells or nano-lipobubbles can include an essential fatty acid or can be conjugated to a peptide ligand which targets the device to a specific cell into which the therapeutic agent can be delivered. The device can be implanted in the sub-arachnoid space in the region of the frontal lobe of the brain. | 12-26-2013 |
20140004185 | PHARMACEUTICAL COMPOSITION | 01-02-2014 |
20140005269 | POLYMERIC MATRIX OF POLYMER-LIPID NANOPARTICLES AS A PHARMACEUTICAL DOSAGE FORM | 01-02-2014 |
20140023692 | DRUG DELIVERY DEVICE - The invention provides an inflammation-responsive implantable device for the in situ delivery of one or more pharmaceutically active agents to a human or animal. The device comprises two differential release bioresponsive polymeric matrices (BPMs): an outer polymetric matrix and an inner polymeric matrix, both of which contain at least one pharmaceutically active agent or drug, typically an antibiotic and an anti-inflammatory agent, respectively. The therapeutically effective agent may be embedded in nanoparticles or nanobubbles. In response to inflammation, the pharmaceutically active agents are released, but at different rates: the rate of drug release from the inner polymeric matrix is lower than the rate of drug release from the outer polymeric matrix. Suitable polymers for forming the outer and inner polymeric matrices are hyaluronic acid and chitosan, respectively. A method of making the device and a method of treatment are also described. | 01-23-2014 |
20150202153 | LIPOSOMAL DRUG DELIVERY SYSTEM - The invention relates to a drug delivery system, particularly to a liposomal drug delivery system. Most particularly the invention relates to a liposomal drug delivery system for the release of at least one drug compound at a target site within a human or animal body. The invention extends to a method of manufacturing the drug delivery system. | 07-23-2015 |
20150313837 | POLYMERIC HYDROGEL COMPOSITIONS WHICH RELEASE ACTIVE AGENTS IN RESPONSE TO ELECTRICAL STIMULUS - A polymeric hydrogel composition is described for the delivery of a pharmaceutically active agent when an electrical stimulus is applied to the composition. The composition comprises a polymer which forms the hydrogel, such as poly vinyl alcohol (PVA) cross-linked with diethyl acetamidomalonate (DAA), an electroactive polymer such as polyaniline and a pharmaceutically active agent such as an analgesic, and in particular, indomethacin. The composition can be subcutaneously implanted at a targeted site and under normal conditions, the active agent will be entrapped in the hydrogel itself. However, upon the application of an electric current to the hydrogel, the active agent will be released. When the electric current is removed, the change is reversed and the active agent will cease to be released. In one embodiment of the invention, the hydrogel composition is for use in alleviating chronic pain. | 11-05-2015 |
Patent application number | Description | Published |
20080306806 | METHODS AND APPARATUS FOR DYNAMICALLY ALLOCATING TASKS - The present disclosure provides methods and apparatuses for dynamically allocating tasks. Using the methods and apparatus herein, users can dynamically assign tasks to roles within a workflow process. This allows business process designers to easily create tasks and define roles for those tasks. | 12-11-2008 |
20080307490 | METHODS AND APPARATUS FOR BUILDING AND EXECUTING NATURAL LANGUAGE WORKFLOW FUNCTIONS - The present disclosure provides methods and apparatuses for building and executing natural language policies. Using the methods and apparatus herein, users can easily program policies in a natural language intuitive manner. The user can program the natural language policy without needing to have technical knowledge of the underlying systems and without the assistance of a technical specialist. | 12-11-2008 |
20080312997 | METHODS AND APPARATUS FOR EXPOSING WORKFLOW PROCESS DEFINITIONS AS BUSINESS OBJECTS - The present disclosure provides methods and apparatuses for exposing a workflow processes definition as a business object. Using the methods and apparatus herein, users can access a business object representing a workflow process definition from any system using standard database constructs. The data for the business object may be combined from a variety of existing sources and/or new data. Using the methods and apparatus a user may generate reports from the business object. | 12-18-2008 |
20080319813 | METHODS AND APPARATUS FOR COLLABORATIVE PROCESS MODELING - The present disclosure provides methods and apparatuses for collaborative process modeling. Using the methods and apparatus herein, users can utilize a plurality of modeling canvases with a plurality of functionality levels during business process design. Additionally, a plurality of users can work collaboratively on a single business process design. | 12-25-2008 |