Dorgan
Andrew J. Dorgan, Edwardsville, IL US
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20120145808 | METHOD AND APPARATUS FOR VARIABLE EXHAUST NOZZLE EXIT AREA - A nozzle effective exit area control system is created with a convergent-divergent nozzle with a divergent portion of the nozzle having a wall at a predetermined angle of at least 12° from the freestream direction. Disturbance generators are located substantially symmetrically oppositely on the wall to induce flow separation from the wall with the predetermined wall angle inducing flow separation to extend upstream from each disturbance generator substantially to a throat of the nozzle pressurizing the wall and reducing the effective area of the jet flow at the nozzle exit. | 06-14-2012 |
20140145001 | METHOD AND APPARATUS FOR NOZZLE THRUST VECTORING - A thrust vectoring system is created with a convergent-divergent nozzle having a total angle no greater than 150 degrees. A divergent portion of the nozzle has a wall at a predetermined angle of at least 12° from the freestream direction. A disturbance generator is located on the wall to induce flow separation from the wall with the predetermined wall angle sufficient for the induced flow separation to extend upstream from disturbance generator substantially to a throat of the nozzle pressurizing the wall and creating a net vector angle in jet flow through the nozzle. | 05-29-2014 |
20150354498 | METHOD AND APPARATUS FOR VARIABLE EXHAUST NOZZLE EXIT AREA - A nozzle effective exit area control system is created with a convergent—divergent nozzle with a divergent portion of the nozzle having a wall at a predetermined angle of at least 12° from the freestream direction. Disturbance generators are located substantially symmetrically oppositely on the wall to induce flow separation from the wall with the predetermined wall angle inducing flow separation to extend upstream from each disturbance generator substantially to a throat of the nozzle pressurizing the wall and reducing the effective area of the jet flow at the nozzle exit. | 12-10-2015 |
Colin Richard Dorgan, Abingdon GB
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20100035956 | Compounds Having CRTH2 Antagonist Activity - Compounds of general formula (I) wherein R is phenyl optionally substituted with one or more halo substituents; and their pharmaceutically acceptable salts, hydrates, solvates, complexes or prodrugs are useful in orally administrable compositions for the treatment of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis. | 02-11-2010 |
20100048660 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY - There are disclosed compound of Formula (I) or (II) wherein A | 02-25-2010 |
20100168072 | Drug Combinations for the Treatment of Duchenne Muscular Dystrophy - Combinations comprising (or consisting essentially of) one or more compounds of the formula (I) or (II) with one or more ancillary compounds, to processes for preparing the combinations, and to various therapeutic uses of the combinations. Also provided are pharmaceutical compositions containing the combinations as well as a method of treatment of Duchenne muscular dystrophy, Becker muscular dystrophy or cachexia using the combinations. | 07-01-2010 |
20110195929 | COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS - Described are various compounds and methods for the treatment of flaviviral infections. In particular, alkaloids and imino sugars in arabinose and/or lyxose stereochemical configuration with antiflaviviral activity are described. | 08-11-2011 |
20110237538 | TREATMENT OF LYSOSOMAL STORAGE DISORDERS AND OTHER PROTEOSTATIC DISEASES - Described are various compounds, in particular iminosugars, and methods for the treatment of proteostatic diseases, in particular lysosomal storage disorders. The compound may be a pharmacoperone of an enzyme selected from: (a) Acid alpha-glucosidase; (b) Acid beta-glucosidase; (c) glucocerebrosidase; (d) alpha-Galactosidase A; (e) Acid beta-galactosidase; (f) beta-Hexosaminidase A; (g) beta-Hexosaminidase B; (h) Acid sphingomyelinase; (i) Galactocerebrosidase; (j) Acid ceramidase; (k) Arylsulfatase A; (l) alpha-L-Iduronidase; (m) Iduronate-2-sulfatase; (n) Heparan N-sulfatase; (o) alpha-N-Acetylglucosaminidase; (p) Acetyl-CoA: alpha-glucosaminide N-acetyltransferase; (q) N-Acetylglucosamine-6-sulfate sulfatase; (r) N-Acetylgalactosamine-6-sulfate sulfatase; (s) Acid beta-galactosidase; (t) Arylsulfatase B; (u) beta-Glucuronidase; (v) Acid alpha-mannosidase; (w) Acid beta-mannosidase; (x) Acid alpha-L-fucosidase; (y) Sialidase; and (z) alpha-N-acetylgalactosaminidase. | 09-29-2011 |
20110268693 | Compounds Having CRTH2 Antagonist Activity - Compounds of general formula (I) wherein R is phenyl optionally substituted with one or more halo substituents; and their pharmaceutically acceptable salts, hydrates, solvates, complexes or prodrugs are useful in orally administrable compositions for the treatment of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis. | 11-03-2011 |
20150150861 | ANTIBACTERIAL COMPOUNDS - Disclosed are compounds of formula (I): | 06-04-2015 |
20150209340 | COMPOUNDS FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASE - Disclosed are compounds of formula (I): | 07-30-2015 |
Colin Richard Dorgan, Abingdon Oxfordshire GB
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20130095057 | COMPOUNDS FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE-ASSOCIATED DISEASE - Disclosed are compounds of formula (I): | 04-18-2013 |
20130309191 | COMPOUNDS FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE-ASSOCIATED DISEASE - Disclosed are compounds of formula (I): | 11-21-2013 |
20140073801 | PYRROLIDINE DERIVATIVES AS SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF - Disclosed are compounds of formula (I): | 03-13-2014 |
Colin Richard Dorgan, Oxfordshire GB
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20110195932 | Drug Combinations for the Treatment of Duchenne Muscular Dystrophy - Combinations comprising (or consisting essentially of) one or more compounds of formula (1) with one or more ancillary agents, to processes for preparing the combinations, and to various therapeutic uses of the combinations. Also provided are pharmaceutical compositions containing the combinations as well as a method of treatment of Duchenne muscular dystrophy, Becker muscular dystrophy or cachexia using the combinations. | 08-11-2011 |
20120020950 | ANTIBACTERIAL COMPOUNDS - Disclosed are compounds of formula (I), which are of use in the treatment of bacterial diseases and infections, to compositions containing those compounds and to methods of treating bacterial diseases and infections using the compounds. In particular, the compounds are useful for the treatment of infection with, and diseases caused by, | 01-26-2012 |
Colin Richard Dorgan, Oxon GB
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20090192195 | Compounds Having CRTH2 Antagonist Activity - Compounds of general formula (I) | 07-30-2009 |
Colin Richard Dorgan, Oxford GB
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20090075938 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY - There are disclosed compound of Formula (1): A | 03-19-2009 |
20140018320 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY - There are disclosed compound of Formula (1): A | 01-16-2014 |
John R. Dorgan, Golden, CO US
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20080254209 | POLYMER ICE AND METHODS OF MAKING AND USING THE SAME - The development provides polymer compositions that may restrict mobility of moving people, animals and objects within an area, including individual combatants and vehicles. The polymer-based compositions create an artificial ice material to directedly and reversibly reduce ground traction. The development also may include a non-toxic reversal agent, matched to the chemical characteristics of the polymer compositions, that restores traction when applied to a surface coated with the initial, traction-reducing polymer. | 10-16-2008 |
20090292046 | HIGH MODULUS POLYMER COMPOSITES AND METHODS OF MAKING THE SAME - The invention provides methods of producing composite polymers by combining fillers with polymers in the presence of pre-formed high molecular weight polymer. Monomer polymerization can be initiated through the addition of initiators or by reactive chemical groups on the surface of the fibers. The composite materials formed possess superior mechanical properties compared to similar polymer composites made by either purely mechanical mixing or solely polymerization of monomers in the presence of the fillers. | 11-26-2009 |
20110319509 | POLYMER COMPOSITES INCORPORATING STEREOCOMPLEXATION - Grafting polymer chains onto filler particles is an established methodology for creating superior polymer composite materials. Stereocomplexation is a non-bonded interaction between polymers that leads to a crystalline form having a higher melting temperature than the non-stereocomplexed form; stereocomplexed polymers often have superior properties compared to their non-stereocomplexed constituents. The present application discloses combining grafted filler particles with matrix materials in which the grafted polymer layer forms a stereocomplex with the polymer matrix. The resulting composite materials have properties which exceed both filled polymer systems and stereocomplexed polymers. | 12-29-2011 |
20130281582 | POLYLACTIDE-GRAFT-LIGNIN BLENDS AND COPOLYMERS - The present invention is directed to a PLA-graft-lignin polymers and copolymers and methods of making the same. As the lignocellulosic biorefining industry emerges as a viable fuels technology, the availability of the assortment of lignins will also expand. The use of lignins as a copolymer is one area where lignin may be utilized. | 10-24-2013 |
20140066608 | LIGNIN EXTRACTION FROM LIGNOCELLULOSICS - The present invention is directed to a method to extract lignin from lignocellulosic biomass using lactic acid. | 03-06-2014 |
20150038652 | BLENDS OF BIORENEWABLE POLYAMIDES AND METHODS OF MAKING THE SAME - The invention discloses a method to produce a blended polymer by mixing polyamide 11 and polyamide 6, 10. The method may be utilize melt mixing or may utilize blended solutions. The invention also includes a blended polymer, wherein the blended polymer is produced from polyamide 11 and polyamide 6,10. | 02-05-2015 |
Kathleen Dorgan, Pullman, WA US
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20100291605 | ASSAYS FOR S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES - Disclosed are novel methyltransferase assay methods, comprising: including, in a reaction mixture for a methyltransferase activity, a purified or recombinant adenosine nucleosidase activity that catalyses release of an adenine or adenine derivative moiety from a transmethylation product, and a purified or recombinant adenine deaminase activity that catalyses deamination of the released moiety to hypoxanthine or respective derivative and ammonia, wherein the methyltransferase activity is rate-limiting; and determining the methyltransferase activity by spectrophotometric or chromatographic monitoring of the coupled deamination reaction products, or of subsequent enzymatic or chemical reactions coupled thereto. Coupled oxidation of the hypoxanthine to uric acid and hydrogen peroxide is optionally affected using purified or recombinant xanthine oxidase, wherein the methyltransferase activity is rate-limiting, and wherein determining the methyltransferase activity comprises monitoring of the coupled oxidation reaction. Variations are disclosed comprises monitoring of reaction products (e.g., to detect NH3, Hypoxanthine, H2O2, and Uric Acid). | 11-18-2010 |
Kelly Dorgan, La Jolla, CA US
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20120234102 | Method and Apparatus for Investigating Mechanical Properties of Soft Materials - A method and apparatus for investigating subsurface properties of sediment, soil, snow, food stuff and other soft materials incorporates a probe head, preferably in the form of a coil spring that functions as a screw thread, which moves into the soil, snow, sediment, food stuff or other soft material, isolates a column of the material and applies tension to that column while measuring the applied force with a force sensor. | 09-20-2012 |
Peter Dorgan, Ontario CA
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20150344179 | COMPACT STACKABLE TRAY - A compact stackable tray system is disclosed wherein in a first orientation the supports of a lower tray maintain an upper tray away from the lower tray such that one of a plurality of standard milk containers stored on the lower tray may be freely removed and in a second orientation wherein the supports of the lower tray nest within the support of the upper tray such that the lower surface of the upper tray rests against the upper surface of the lower tray. | 12-03-2015 |
Philip David Dorgan, Newcastle Upon Tyne GB
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20130324456 | SPRAY-DRIED DETERGTENT POWDER - The present invention is a spray-dried powder comprising: at least 5 wt % of a spray-dried particle comprising at least 40 wt % anionic detersive surfactant, from 15 to 40 wt % carbonate and less than 20 wt % sulphate and having a bulk density of from 300 g/l to 450 g/l. | 12-05-2013 |
Roderick John Jeremiah Dorgan, Sandwich GB
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20100105649 | VETERINARY COMPOSITIONS FOR TREATING MASTITIS - The present invention relates to a veterinary composition for the prophylaxis and treatment of mastitis in mammals, preferably cows. The formulations of the present invention comprise two parts that are optionally administered to the animal as a blended formulation or two separate formulations. The first part is a seal formulation comprising a gel base and a non-toxic heavy metal salt in the base. The second part of the formulation is an oil-based product preferably containing an antibiotic in an oil-based formulation. The oil-based formulation may also optionally contain any other pharmaceutically active agent for the treatment or prophylaxis of disease in cattle. | 04-29-2010 |
Roderick John Jeremiah Dorgan, Reigate GB
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20160030398 | VETERINARY COMPOSITIONS FOR TREATING MASTITIS - The present invention relates to a veterinary composition for the prophylaxis and treatment of mastitis in mammals, preferably cows. The formulations of the present invention comprise two parts that are optionally administered to the animal as a blended formulation or two separate formulations. The first part is a seal formulation comprising a gel base and a non-toxic heavy metal salt in the base. The second part of the formulation is an oil-based product preferably containing an antibiotic in an oil-based formulation. The oil-based formulation may also optionally contain any other pharmaceutically active agent for the treatment or prophylaxis of disease in cattle. | 02-04-2016 |
Stephen E. Dorgan, Hoffman Estates, IL US
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20080201910 | Apparatus And Method For Holding Garments - An improved apparatus and method for holding garments, such as neckties, is disclosed. The device comprises a magnet, preferably made of a rare Earth material and magnetized to about Grade N35 or better, and a faceplate. In one embodiment, the magnet is positioned under at least a portion of the wearer's shirt while the faceplate is positioned on a portion of the wearer's necktie. The shirt and/or necktie may additionally include pockets for housing the magnet and/or faceplate. The faceplate may be decorative, and interchangeable, for prominent display in front of the necktie. Alternatively, the device may be configured to be completely hidden from view. Several means for retaining the magnet to the shirt upon separation of the garments are presented. | 08-28-2008 |