Doolan
Denise Doolan, Queensland AU
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20110229514 | VACCINE AND IMMUNIZATION METHOD USING PLASMODIUM ANTIGEN 2 - A vaccine comprising an immunogenic preparation containing a | 09-22-2011 |
Denise Doolan, Camp Hill AU
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20150079126 | Plasmodium falciparum antigens - The invention relates to antigens, associated with sterile immunity, and methods of their use, in an immunogenic formulation to confer an immune response against | 03-19-2015 |
20160083438 | Plasmodium falciparum antigens - The invention relates to antigens, associated with sterile immunity, and methods of their use, in an immunogenic formulation to confer an immune response against | 03-24-2016 |
Denise Doolan, Qld AU
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20120244178 | Plasmodium falciparum antigens - The invention relates to antigens, associated with sterile immunity, and methods of their use, in an immunogenic formulation to confer an immune response against | 09-27-2012 |
Denise L. Doolan, Camp Hill AU
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20080219930 | Method for the evaluation of dengue virus therapeutic agents - The inventive subject matter relates to a method for evaluating potential compounds and vaccines for the prevention or treatment of dengue virus infection. The method utilizes pigs as an animal model for the evaluation of test vaccine or drug compounds. The breeds that can be utilized and in the inventive method include Yorkshire or Lancashire as well as miniature pig breeds. | 09-11-2008 |
Denise L. Doolan, Rockville, MD US
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20120015401 | PLASMODIUM FALCIPARUM ANTIGENS AND METHODS OF USE - The subject invention provides novel | 01-19-2012 |
20120196289 | NOVEL ASSAY FOR DETECTING IMMUNE RESPONSES INVOLVING ANTIGEN SPECIFIC CYTOKINE AND/OR ANTIGEN SPECIFIC CYTOKINE SECRETING T-CELLS - Here, we describe a sensitive and specific assay and kit for the detection of chemokines having activity that is upregulated by Th-1 cytokines (such IFN-γ) and chemokines that upregulate the activity of Th-1 cytokines (such as IFN-γ). In a typical embodiment, detection of the chemokine monokine induced by gamma interferon (MIG) provides a measure of the biological effect of IFN-γ rather than direct quantitation of IFN-γ or IFN-γ secreting cells per se. Upregulation of MIG expression was observed following in vitro activation of PBMC with defined CD8 | 08-02-2012 |
Denise Louis Doolan, Camp Hill AU
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20080248060 | ADENOVIRAL VECTOR-BASED MALARIA VACCINES - The invention provides a method of inducing an immune response against malaria in a mammal. The method comprises intramuscularly administering to a mammal a composition comprising a pharmaceutically acceptable carrier and either or both of (a) a first adenoviral vector comprising a nucleic acid sequence encoding a | 10-09-2008 |
20090148477 | ADENOVIRAL VECTOR-BASED MALARIA VACCINES - The invention provides adenoviral vectors comprising an adenoviral genome comprising heterologous antigen-encoding nucleic acid sequences, such as | 06-11-2009 |
Denise Louise Doolan, Camp Hill AU
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20100222234 | Malaria antigen screening method - The invention provides a method of identifying an antigen from a pathogen or a disease antigen comprising the use of an adenoviral vector array comprising two or more different adenoviral vectors, wherein each adenoviral vector comprises a nucleic acid sequence encoding a different antigen of a pathogen. The adenoviral vectors are administered to antigen presenting cells (APCs) in vitro or to an animal in vivo. The immunogenicity of the antigen is measured by screening for an immune response from effector T lymphocytes in vitro and by screening for the absence of pathogen-induced disease onset in vivo. | 09-02-2010 |
20100278870 | ADENOVIRAL VECTOR-BASED MALARIA VACCINES - The invention provides a method of inducing an immune response against malaria in a mammal. The method comprises intramuscularly administering to a mammal a composition comprising a pharmaceutically acceptable carrier and either or both of (a) a first adenoviral vector comprising a nucleic acid sequence encoding a | 11-04-2010 |
20140314809 | MALARIA ANTIGEN SCREENING METHOD - The invention provides a method of identifying an antigen from a pathogen or a disease antigen comprising the use of an adenoviral vector array comprising two or more different adenoviral vectors, wherein each adenoviral vector comprises a nucleic acid sequence encoding a different antigen of a pathogen. The adenoviral vectors are administered to antigen presenting cells (APCs) in vitro or to an animal in vivo. The immunogenicity of the antigen is measured by screening for an immune response from effector T lymphocytes in vitro and by screening for the absence of pathogen-induced disease onset in vivo. | 10-23-2014 |
20140335128 | ADENOVIRAL VECTOR-BASED MALARIA VACCINES - The invention provides a method of inducing an immune response against malaria in a mammal. The method comprises intramuscularly administering to a mammal a composition comprising a pharmaceutically acceptable carrier and either or both of (a) a first adenoviral vector comprising a nucleic acid sequence encoding a | 11-13-2014 |
Gavin Doolan, Dublin IE
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20150154519 | ANALYZING INCOMPLETE TRANSACTIONS - Analyzing incomplete transactions may be used to improve an online retailer's ability to market and sell items, such as products and/or services. A transaction may begin by a user selecting an item to be added to a virtual shopping cart. Data related to the item and the pending transaction may be stored in a data structure. If a transaction is not completed, the data may be used to determine a context of for the incomplete transaction. Based on the context, a report may be generated. In some instances, a feedback feature, such as a pop-up window, may be provided to the user if the user removes the item from the shopping cart. | 06-04-2015 |
Joseph G. Doolan, Emeryville, CA US
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20120165474 | POLYFARNESENES - Provided herein are polyfarnesenes derived from a farnesene and at least two different vinyl monomers. Also provided herein are polyfarnesenes derived from a farnesene; at least two different vinyl monomers, such as (meth)acrylic acid, (meth)acrylic esters, styrene, and substituted styrenes; and at least one functional comonomer such as maleic anhydride. | 06-28-2012 |
20140357533 | DRILLING FLUIDS COMPRISING FARNESANE AND/OR FARNESENE - Provided herein are drilling fluids comprising microbial-derived bio-organic compounds, a weighting agent and a viscosifier. In some embodiments, the microbial-derived bio-organic compounds comprise a famesane, a farnesene or a combination thereof. In certain embodiments, the drilling fluid comprises a continuous phase comprising a famesane, a farnesene or a combination thereof; and a discontinuous phase comprising water or an aqueous solution, an emulsifier, a weighting agent and a viscosifier. In other embodiments, the viscosifier is an organophillic clay. | 12-04-2014 |
20150025193 | POLYMERIZATION OF COMPOSITIONS COMPRISING A FARNESENE - Provided herein are polyfarnesenes such as farnesene homopolymers derived from a farnesene and farnesene interpolymers derived from a farnesene and at least a vinyl monomer; and the processes of making and using the polyfarnesenes. The farnesene homopolymer can be prepared by polymerizing the farnesene in the presence of a catalyst. In some embodiments, the farnesene is prepared from a sugar by using a microorganism. | 01-22-2015 |
Michael Charles Doolan, Brigstock GB
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20130156887 | HYDROLYSED MARINE PROTEIN PRODUCT, PROCESS FOR THE PRODUCTION THEREOF, AND APPLICATION - A hydrolyzed marine protein product, a method for the production of the product, a feed product for animals, including humans, and a culture medium including the hydrolyzed marine protein product. The protein product may be hydrolyzed by enzymatic activity, bacterial activity, acids, cooking or any combination of these. The protein product may also include stickwater peptide fraction containing bioactive peptides. Feed product could be any nutritional product comsumable by any animal including humans. | 06-20-2013 |
Padraig Doolan, Swords IE
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20090017460 | DIFFERENTIAL EXPRESSION PROFILING ANALYSIS OF CELL CULTURE PHENOTYPES AND USES THEREOF - The present invention provides, among other things, systems and methods for identifying genes and proteins that regulate and/or are indicative of cell phenotypes based on expression profiling analysis. The present invention further provides methods of manipulating identified genes and proteins to engineer improved cell lines. | 01-15-2009 |
20090186358 | Pathway Analysis of Cell Culture Phenotypes and Uses Thereof - The present invention provides methods for systematically identifying genes, proteins and/or related pathways that regulate or indicative of cell phenotypes. The present invention further provides methods for manipulating the identified genes, proteins and/or pathways to engineer improved cell lines and/or to evaluate or select cell lines with desirable phenotypes. | 07-23-2009 |
Rick Doolan, Burnaby CA
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20100276611 | HIGH-INTENSITY ELECTROMAGNETIC RADIATION APPARATUS AND METHODS - An apparatus for producing electromagnetic radiation includes a flow generator configured to generate a flow of liquid along an inside surface of an envelope, first and second electrodes configured to generate an electrical arc within the envelope to produce the electromagnetic radiation, and an exhaust chamber extending outwardly beyond one of the electrodes, configured to accommodate a portion of the flow of liquid. In another aspect, the flow generator is electrically insulated. In another aspect, the electrodes are configured to generate an electrical discharge pulse to produce an irradiance flash, and the apparatus includes a removal device configured to remove particulate contamination from the liquid, the particulate contamination being released during the flash and being different than that released by the electrodes during continuous operation. | 11-04-2010 |
William Doolan, Alpharettan, GA US
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20140062152 | Reclinable Child Seat Assembly - A child seat assembly has a base to rest on a vehicle seat, a seat shell, and a recline mechanism that selectively permits adjustment of the seat shell between first and second recline positions and includes a recline positioner, pin, biasing element, and handle. The recline positioner has first and second portions defining the first and second recline positions, respectively. The pin is movable between a released position and an engaged position in which the pin is configured to engage the first or second portion to retain the seat shell in the corresponding first or second recline position. The biasing element is coupled to the pin and configured to bias the pin to the engaged position. The handle is operable to move the pin from the engaged position to the released position in which the seat shell is movable between the first and second recline positions. | 03-06-2014 |
William Doolan, Clover, SC US
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20160068083 | CENTER-PULL LATCH MECHANISM - A base for a safety seat and method for manufacturing the same are provided. The base may have a shell defining a cavity therein with a locking assembly disposed within the cavity. The base may further include one or more straps having a first end and a second end extending through the locking assembly releasably engaging the straps with the first and second ends being disposed on opposing sides of the locking assembly. The straps may define a first portion extending from a connector to the locking assembly and a second portion extending from the locking assembly to the second ends. A tensioning assembly may be provided to apply a tension to the second portions. The one or more straps may include two straps configured to be accessed by a user parallel to a centerline of the base. | 03-10-2016 |
William S. Doolan, Atlanta, GA US
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20100126833 | Method for Assembling a Portable Device Configured with an Energy Storage Device | 05-27-2010 |