Donald, US
Bruce R. Donald, Durham, NC US
Patent application number | Description | Published |
---|---|---|
20130060005 | COMPOSITIONS AND METHODS FOR INHIBITING THE INTERACTION BETWEEN CFTR AND CAL - The present invention features compositions and methods for increasing the cell surface expression of degradation-prone CFTR proteins and preventing or treating cystic fibrosis. The invention provides peptides and peptidomimetics that selectively inhibit the interaction between CAL and mutant CFTR proteins, thereby stabilizing the CFTR and facilitating transport of the same to the cell surface. | 03-07-2013 |
Carlton D. Donald, Mount Pleasant, SC US
Patent application number | Description | Published |
---|---|---|
20100029504 | DETECTING PAX2 FOR THE DIAGNOSIS OF BREAST CANCER - A method for monitoring breast conditions in a subject is disclosed. The method comprises determining a Paired Box 2 gene-to-beta defensin- | 02-04-2010 |
20100029560 | COMPOSITIONS AND METHODS FOR DIAGNOSING, TREATING, AND PREVENTING PROSTATE CONDITIONS - Disclosed are compositions and methods for diagnosing, preventing, and treating prostate cancer and prostate intraepithelial neoplasia (PIN). | 02-04-2010 |
20100196450 | TARGETING PAX2 FOR THE INDUCTION OF DEFBI-MEDIATED TUMOR IMMUNITY AND CANCER THERAPY - Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 08-05-2010 |
20100209421 | TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER - The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the certain embodiments, the method of inhibiting expression of PAX2 is to administrate the subject a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 or by increasing expression of DEFB1 is also provided. | 08-19-2010 |
20110177075 | TARGETING PAX2 FOR THE INDUCTION OF DEFB1-MEDIATED TUMOR IMMUNITY AND CANCER THERAPY - Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 07-21-2011 |
20110177100 | TARGETING PAX2 FOR THE INDUCTION OF DEFB1-MEDIATED TUMOR IMMUNITY AND CANCER THERAPY - Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 07-21-2011 |
20110177101 | TARGETING PAX2 FOR THE INDUCTION OF DEFB1-MEDIATED TUMOR IMMUNITY AND CANCER THERAPY - Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 07-21-2011 |
20110178162 | TARGETING PAX2 FOR THE INDUCTION OF DEFB1-MEDIATED TUMOR IMMUNITY AND CANCER THERAPY - Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 07-21-2011 |
20110206665 | TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER - The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 08-25-2011 |
20110206666 | TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER - The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 08-25-2011 |
20110212089 | TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER - The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 09-01-2011 |
20110217299 | TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER - The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 09-08-2011 |
20110223161 | TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER - The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 09-15-2011 |
20110223162 | TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER - The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB 1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 09-15-2011 |
20110229467 | TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER - The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 09-22-2011 |
20110229468 | TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER - The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 09-22-2011 |
20110229492 | COMPOSITIONS AND METHODS FOR DIAGNOSING, TREATING, AND PREVENTING PROSTATE CONDITIONS - Disclosed are compositions and methods for diagnosing, preventing, and treating prostate cancer and prostate intraepithelial neoplasia (PIN). | 09-22-2011 |
20110236403 | TARGETING PAX2 FOR THE INDUCTION OF DEFB1-MEDIATED TUMOR IMMUNITY AND CANCER THERAPY - Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 09-29-2011 |
20110243937 | TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER - The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 10-06-2011 |
20110318338 | TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER - The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. | 12-29-2011 |
20120058130 | COMPOSITIONS AND METHODS FOR DIAGNOSING, TREATING, AND PREVENTING PROSTATE CONDITIONS - Disclosed are compositions and methods for diagnosing, preventing, and treating prostate cancer and prostate intraepithelial neoplasia (PIN). | 03-08-2012 |
20120071347 | COMPOSITIONS AND METHODS FOR MONITORING AND DETECTING CANCEROUS CONDITIONS - A method for monitoring or detecting a prostate condition in a subject comprises determining Engrailed-2 (EN2) gene, Paired Box 2 (PAX2) gene, and/or β defensin-1 (DEFB1) gene expression levels in a biological sample from the subject. The expression levels of EN2, PAX2 and/or DEFB1 gene are correlated with cancerous, pre-cancerous, or non-cancerous prostate conditions. | 03-22-2012 |
20120157508 | TARGETING EN2, PAX2, AND/OR DEFB1 FOR TREATMENT OF PROSTATE CONDITIONS - The present invention relates to methods and compositions for treating a prostate condition in a subject. The method comprises administering to the subject a subject effective amount of a pharmaceutical composition having a first agent that inhibits EN2 expression and/or EN2 activity and a second agent that inhibits PAX2 expression and/or PAX2 activity. The pharmaceutical composition may further comprise a third agent that enhances DEFB1 expression or activity. | 06-21-2012 |
Carlton D. Donald, Atlanta, GA US
Patent application number | Description | Published |
---|---|---|
20130023424 | DETECTING PAX2 FOR THE DIAGNOSIS OF BREAST CANCER - A method for monitoring breast conditions in a subject is disclosed. The method comprises determining a Paired Box 2 gene-to-beta defensin-1 gene (PAX2-to-DEFB1) expression ratio (the “Donald Predictive Factor” or “DPF”) in cells obtained from the breast of the subject, wherein the PAX2-to-DEFB1 expression ratio is correlated with breast conditions. Also disclosed is a kit for monitoring breast conditions and determining drug resistance. | 01-24-2013 |
20130023425 | DETECTING PAX2 FOR THE DIAGNOSIS OF BREAST CANCER - A method for monitoring breast conditions in a subject is disclosed. The method comprises determining a Paired Box 2 gene-to-beta defensin-1 gene (PAX2-to-DEFB1) expression ratio (the “Donald Predictive Factor” or “DPF”) in cells obtained from the breast of the subject, wherein the PAX2-to-DEFB1 expression ratio is correlated with breast conditions. Also disclosed is a kit for monitoring breast conditions and determining drug resistance. | 01-24-2013 |
20130296403 | TARGETING EN2, PAX2, AND/OR DEFB1 FOR TREATMENT OF PROSTATE CONDITIONS - The present invention relates to methods and compositions for treating a prostate condition in a subject. The method comprises administering to the subject a subject effective amount of a pharmaceutical composition having a first agent that inhibits EN2 expression and/or EN2 activity and a second agent that inhibits PAX2 expression and/or PAX2 activity. The pharmaceutical composition may further comprise a third agent that enhances DEFB1 expression or activity. | 11-07-2013 |
20140135378 | TARGETING EN2, PAX2, AND/OR DEFB1 FOR TREATMENT OF PROSTATE CONDITIONS - The present invention relates to methods and compositions for treating a prostate condition in a subject. The method comprises administering to the subject a subject effective amount of a pharmaceutical composition having a first agent that inhibits EN2 expression and/or EN2 activity and a second agent that inhibits PAX2 expression and/or PAX2 activity. The pharmaceutical composition may further comprise a third agent that enhances DEFB1 expression or activity. | 05-15-2014 |
20140323349 | COMPOSITIONS AND METHODS FOR MONITORING AND DETECTING CANCEROUS CONDITIONS - A method for monitoring or detecting a prostate condition in a subject comprises determining Engrailed-2 (EN2) gene, Paired Box 2 (PAX2) gene, and/or β defensin-1 (DEFB1) gene expression levels in a biological sample from the subject. The expression levels of EN2, PAX2 and/or DEFB1 gene are correlated with cancerous, pre-cancerous, or non-cancerous prostate conditions. | 10-30-2014 |
20140336130 | TARGETING EN2, PAX2, AND/OR DEFB1 FOR TREATMENT OF PROSTATE CONDITIONS - The present invention relates to the compositions and use of compositions for treating a prostate condition in a subject. The use of composition comprises administering to the subject a subject effective amount of a pharmaceutical composition having a first agent that inhibits EN2 expression and/or EN2 activity and a second agent that inhibits PAX2 expression and/or PAX2 activity. The pharmaceutical composition may further comprise a third agent that enhances DEFB1 expression or activity. | 11-13-2014 |
David M. Donald, Houston, TX US
Patent application number | Description | Published |
---|---|---|
20130015115 | NOVEL INJECTION FLOCCULATION AND COMPRESSION DEWATERING UNIT FOR SOLIDS CONTROL AND MANAGEMENT OF DRILLING FLUIDS AND METHODS RELATING THERETOAANM Landis; Charles R.AACI The WoodlandsAAST TXAACO USAAGP Landis; Charles R. The Woodlands TX USAANM Collins; Ryan P.AACI SpringAAST TXAACO USAAGP Collins; Ryan P. Spring TX USAANM Anderson; Edward A.AACI SpringAAST TXAACO USAAGP Anderson; Edward A. Spring TX USAANM Donald; David M.AACI HoustonAAST TXAACO USAAGP Donald; David M. Houston TX USAANM Pullman; Douglas G.AACI WatfordAACO CAAAGP Pullman; Douglas G. Watford CAAANM Woods; Roger H.AACI WatfordAACO CAAAGP Woods; Roger H. Watford CA - A flocculation and dewatering system may include a solid-liquid sorter; a flocculation chamber including a flocculation trough that comprises at least one baffle; an injection port for introducing a flocculant; and an outlet for removing a flocculated fluid; a dewatering rack in which the outlet introduces the flocculated fluid into the dewatering rack that comprises at least one filtration collection bag; a filter press; and a pump for pumping fluids in a conduit network running at least partially through the flocculation and dewatering system. | 01-17-2013 |
20130015141 | NOVEL INJECTION FLOCCULATION AND COMPRESSION DEWATERING UNIT FOR SOLIDS CONTROL AND MANAGEMENT OF DRILLING FLUIDS AND METHODS RELATING THERETOAANM Landis; Charles R.AACI The WoodlandsAAST TXAACO USAAGP Landis; Charles R. The Woodlands TX USAANM Collins; Ryan P.AACI SpringAAST TXAACO USAAGP Collins; Ryan P. Spring TX USAANM Anderson; Edward A.AACI SpringAAST TXAACO USAAGP Anderson; Edward A. Spring TX USAANM Woods; Roger H.AACI WatfordAACO CAAAGP Woods; Roger H. Watford CAAANM Pullman; Douglas G.AACI WatfordAACO CAAAGP Pullman; Douglas G. Watford CAAANM Donald; David M.AACI HoustonAAST TXAACO USAAGP Donald; David M. Houston TX US - A method may include providing a returned fluid comprising a fluid; and a solid contaminant; introducing the returned fluid into a solid-liquid sorter thereby separating the returned fluid into an overflow and underflow; flocculating the underflow in a flocculating chamber thereby forming a flocculated fluid; and dewatering the flocculated fluid using a dewatering rack. | 01-17-2013 |
20140121134 | Drilling Fluid Compositions and Methods for Use Thereof in Subterranean Formations - A method comprising drilling a wellbore into a subterranean formation; providing a drilling fluid comprising an aqueous base fluid and a property control package, the property control package comprising: a stabilizing agent; a filtration control agent; and a suspension enhancer; introducing the drilling fluid into the wellbore in the subterranean formation; and continuously circulating the drilling fluid during the drilling of the wellbore. | 05-01-2014 |
20160052805 | ELECTRO-COAGULATION AND METAL SAND TREATMENT FOR WASTEWATER - Improved methods and systems for treating wastewaters produced in mining and/or subterranean well bore operations are provided. In one embodiment, the systems comprise: an electro-coagulation unit that receives wastewater from a wastewater source, performs an electro-coagulation treatment on the wastewater using one or more EC cells, and produces a first fluid stream that comprises one or more solid materials and a liquid effluent; a solids separation unit coupled downstream of and in fluid communication with the electro-coagulation unit that separates at least a portion of the solid materials in the first fluid stream from the liquid effluent; and a filter comprising a metal-bearing filtration media coupled downstream of and in fluid communication with the solids separation unit that filters the liquid effluent from the solids separation unit to produce a treated water stream. | 02-25-2016 |
Douglas Donald, Edmond, OK US
Patent application number | Description | Published |
---|---|---|
20120043732 | DOLLY - A dolly has a frame with a pair of risers connected thereto. Connecting bolts extend partially through the risers and through the frame to connect the risers and casters to the frame. The risers have an outer riser body with a core disposed therein. The outer riser body may be a thermoplastic injection molded riser body that is molded around a riser core which may be a metal riser plate core. | 02-23-2012 |
Elizabeth Donald, Pleasanton, CA US
Patent application number | Description | Published |
---|---|---|
20120145086 | Animal Litter Comprising A Surfactant Encapsulated Fragrance Nanoemulsion - The present invention is directed to litter compositions including a litter substrate in the form of granules and a stable fragrance coating applied over at least some of the litter granules. The stable fragrance coating provides a fragrance litter composition exhibiting no or a reduced tendency for fragrance to be lost over time. Furthermore, the fragrant litter composition is able to reform a stable fragrance coating after being wetted, upon redrying. The stable fragrance coating comprises a nanoemulsion including an aqueous surfactant continuous phase and a dispersed phase comprising one or more fragrance oils. The fragrance oil is dispersed within the continuous phase as nano-sized droplets having an average diameter of no more than about 100 nm. | 06-14-2012 |
Elizabeth L. Donald, Pleasanton, CA US
Patent application number | Description | Published |
---|---|---|
20130327678 | GARBAGE DISPOSAL CLEANING POUCH AND METHODS OF USE - This invention relates to compositions and methods to provide an effervescent garbage disposal cleaner. The compositions are contained in a water-soluble film and include encapsulated technologies to isolate ingredients that are sensitive to temperature and humidity fluctuations, and are also prone to react with each other, which would result in comprising the overall product performance. | 12-12-2013 |
Gordon Donald, Red Bank, NJ US
Patent application number | Description | Published |
---|---|---|
20150025573 | TRANSLATIONAL PLATE AND COMPRESSOR INSTRUMENT - A bone plate that is configured to operatively attach to bone includes a first segment, a second segment, and a locking mechanism. The first segment includes a compression notch. The first and second segments are positioned along a longitudinal axis and are movable relative to one another. The locking mechanism inhibits relative axial movement of the first and second segments along the longitudinal axis away from one another. The locking mechanism includes first and second grooves disposed on the second segment. The first and second grooves and the compression slot are configured to receive an instrument to move the first segment towards the second segment along the longitudinal axis. | 01-22-2015 |
20150142062 | CLIP FOR DYNAMIC SPINAL PLATE - A clip includes a body and a pin. The body includes a first end, a second end, and a backspan extending between the first and second ends. The backspan defines a through hole. Each of the first and second ends of the body are configured to releasably couple to a rail of a dynamic spinal clip between two adjacent segments of a dynamic spinal clip to maintain a span between two adjacent segments. The pin defines a longitudinal axis and includes a head and a shaft. The shaft extends from the head to a tip. The tip is configured to penetrate bone. The shaft is configured and dimensioned to be slidably received through the through hole of the body The head is sized to prevent the head from passing through the through hole of the body. | 05-21-2015 |
Gordon Donald, Eatontown, NJ US
Patent application number | Description | Published |
---|---|---|
20150196343 | IMPACTOR AND REMOVER DEVICES - An impactor having a housing including an upper portion and a lower portion at least a part of which extends perpendicularly from the upper portion, a ram having a first end positioned in the upper portion and positioned in axial alignment with the lower portion, an opposite end of the ram extending from the lower portion of the housing, at least one drive assembly including a first drive shaft operably coupled to a cam shaft, a cam operably coupled to the cam shaft, a cam operably coupled to the cam shaft, the drive shaft operably connectable to motor, wherein the cam is operable to rotate and positioned to contact the proximal end of the ram upon rotation of the cam, a circuit board comprising circuitry operable to receive instructions from a plurality of switches electrically coupled to the circuit board to operate the impactor, wherein the impactor is operable to deliver low amplitude pulsed strikes to a workpiece at variable frequencies. | 07-16-2015 |
Gordon D. Donald, Oceanport, NJ US
Patent application number | Description | Published |
---|---|---|
20160120532 | SURGICAL RETRACTOR SYSTEM AND METHOD - A retractor system is provided having a plurality of blade portions that collectively present a low profile tapered configuration for insertion through tissue along a natural tissue plane. Once inserted through tissue the blade portions may be independently moved apart to form an access path to a surgical site, such as by first moving the blade portions apart along the natural tissue plane followed by moving the blade portions apart transverse to the natural tissue plane. The blade portions may be attached to retractor frame members, and rack and pinion frame components may be used to control movement of the blade portions relative to one another. Pins may be used to secure the blade portions to bone. | 05-05-2016 |
J. Donald, Highlands Ranch, CO US
Patent application number | Description | Published |
---|---|---|
20080273422 | METHOD FOR CHARACTERIZING SHEAR WAVE FORMATION ANISOTROPY - A method of characterizing shear wave anisotropy in a formation includes obtaining crossed-dipole waveforms from a borehole penetrating the formation over a range of depths and frequencies, determining far-field slowness in a fast-shear and slow-shear direction using a low-frequency portion of the crossed-dipole waveforms, and determining near-wellbore slowness in the fast-shear and slow-shear directions using a high-frequency portion of the crossed-dipole waveforms. The method also includes marking a selected depth of the formation as having intrinsic anisotropy if at the selected depth the far-field slowness in the fast-shear direction is less than the far-field slowness in the slow-shear direction and the near-wellbore slowness in the fast-shear direction is less than the near-wellbore slowness in the slow-shear direction. The selected depth is marked as having stress-induced anisotropy if the far-field slowness in the fast-shear direction is less than the far-field slowness in the slow-shear direction and the near-wellbore slowness in the fast-shear direction is greater than the near-wellbore slowness in the slow-shear direction. | 11-06-2008 |
Jason Donald, Portland, OR US
Patent application number | Description | Published |
---|---|---|
20130344292 | Three Dimensional Fiducial - A method and system for forming and using a fiducial on a sample to locate an area of interest on the sample, the method comprising forming a fiducial by depositing a block of material on a sample proximal to an area of interest on the sample, the block of material extending from the surface of the sample to a detectable extent above the surface of the sample; and milling, using a charged particle beam, a predetermined pattern into at least two exposed faces of the block of material; subsequent to forming the fiducial, detecting the location of the area of interest by detecting the location of the fiducial; and subsequent to detecting the location of the area of interest, imaging or milling the area of interest with a charged particle beam. | 12-26-2013 |
20160126060 | ENDPOINTING FOR FOCUSED ION BEAM PROCESSING - To expose a desired feature, focused ion beam milling of thin slices from a cross section alternate with forming a scanning electron image of each newly exposed cross section. Milling is stopped when automatic analysis of an electron beam image of the newly exposed cross section shows that a pre-determined criterion is met. | 05-05-2016 |
Jason Donald, Lexington, MA US
Patent application number | Description | Published |
---|---|---|
20150267206 | MULTIPROTEIN EXPRESSION CASSETTES - Methods for expressing multiple proteins by constructing transformation vectors that include multiprotein expression cassettes and transforming hosts with vectors and by engineering hosts expressing multiprotein units are provided. Multiprotein units that include multiple proteins fused to modified inteins capable of effecting splicing of the multiprotein units are described. Expression cassettes that include nucleic acids encoding multiprotein units and hosts including the expression cassettes are also provided. | 09-24-2015 |
20160024485 | USE OF DIMERIZATION DOMAINS FOR TEMPERATURE REGULATION OF ENZYME ACTIVITY - Methods for regulating protein activity by fusing dimerization domains to target protein are provided. Chimeric proteins that include dimerization domains fused to target proteins for altering the activity of the target proteins are described. Engineered nucleic acids encoding chimeric proteins and hosts engineered to express engineered nucleic acids are also provided. | 01-28-2016 |
Mark Louis Donald, Norfolk, VA US
Patent application number | Description | Published |
---|---|---|
20120116278 | Bandage Pack and Method of Packaging - Articles of manufacture, methods for packaging and using bandages are described including an s-folded, or “fan folded”, bandage that is contained in a housing including an opening and a first strip of securing material proximate to the opening. The s-folded bandage may be substantially contained within the housing and may extend at least partially though the opening. The bandage may include a second strip of securing material that is configured to secure with the first strip of securing material. The second strip of securing material may include a hook material that is configured to engage with loops of the first strip of securing material and/or a bandage material of the bandage. The second strip of securing material may be folded over an end of the bandage. Aspects of the invention may provide for a low-profile bandage pack that is relatively convenient to carry and use. | 05-10-2012 |
20120150215 | Junctional Bleed Device - Systems and methods of applying a bandage to a patient including securing a bandage device over a wound and around a body part of the patient. The bandage device includes a platform with a plurality of first openings for use with a tensioning mechanism, and at least one second opening for use with a pressure adjusting mechanism. The pressure adjusting mechanism may include threads, detents, and other adjustable, or semi-permanent, locking mechanisms. In addition to pressure applied to a wound via the tensioning mechanism, an additional pressure may be applied to the wound through the platform of the bandage device via the pressure adjusting mechanism. The pressure adjusting mechanism may have a pressure application mechanism that applies the additional pressure to the wound. | 06-14-2012 |
Matthew Donald, West Palm Beach, FL US
Patent application number | Description | Published |
---|---|---|
20150378334 | Compact Aero-Thermo Model Based Engine Power Control - Systems and methods for controlling a fluid based engineering system are disclosed. The systems and methods may include a model processor for generating a model output, the model processor including a set state module for setting dynamic states of the model processor, the dynamic states input to an open loop model based on the model operating mode, wherein the open loop model generates a current state model as a function of the dynamic states and the model input, wherein a constraint on the current state model is based a series of cycle synthesis modules, each member of the series of cycle synthesis modules modeling a component of a cycle of the control system and including a series of utilities, the utilities are based on mathematical abstractions of physical properties associated with the component. The model processor may further include an estimate state module for determining an estimated state of the model based on a prior state model output and the current state model of the open loop model. | 12-31-2015 |
20160003165 | COMPACT AERO-THERMO MODEL BASED CONTROL SYSTEM - Systems and methods for controlling a fluid based engineering system are disclosed. The systems and methods may include a model processor for generating a model output, the model processor including a set state module for setting dynamic states of the model processor, the dynamic states input to an open loop model based on the model operating mode, wherein the open loop model generates a current state model as a function of the dynamic states and the model input, wherein a constraint on the current state model is based a series of cycle synthesis modules, each member of the series of cycle synthesis modules modeling a component of a cycle of the control system and including a series of utilities, the utilities are based on mathematical abstractions of physical properties associated with the component. The model processor may further include an estimate state module for determining an estimated state of the model based on a prior state model output and the current state model of the open loop model. | 01-07-2016 |
M. Oglesby Donald, Hertford, NC US
Patent application number | Description | Published |
---|---|---|
20090277789 | Wireless Chemical Sensor and Sensing Method for Use Therewith - A wireless chemical sensor includes an electrical conductor and a dielectric material on the conductor. The conductor is electrically unconnected and is shaped for storage of an electric field and a magnetic field. In the presence of a time-varying magnetic field, the conductor resonates to generate harmonic electric and magnetic field responses, each of which has a frequency associated therewith. The dielectric material is selected such that it experiences changes in dielectric attributes thereof in the presence of a chemical-of-interest. Shifts from the sensor's baseline frequency response indicate that the dielectric material has been exposed to the chemical-of-interest. | 11-12-2009 |
Morris Donald, Westland, MI US
Patent application number | Description | Published |
---|---|---|
20150375820 | FOLDABLE ELECTRIC BICYCLE - A foldable bicycle includes a frame, a front wheel assembly, and a rear wheel assembly. The frame defines a pivot axis. The front wheel assembly is disposed on the frame and configured to rotate about the pivot axis. The rear wheel assembly is disposed on the frame and defines an opening for receiving the front wheel assembly when the bicycle is folded. | 12-31-2015 |
Richard J. Donald, Brentwood, CA US
Patent application number | Description | Published |
---|---|---|
20090061824 | MESSAGING WITH MEDIA INTEGRATION - Techniques involving messaging applications are disclosed. For example, an apparatus may include a communications interface module and a messaging module. The communications interface module may receive an incoming message of a conversation thread that is originated by a remote device. The incoming message includes a text portion and an attached media item. The messaging module automatically outputs the incoming message to a user interface in an output format. This output format includes both the text portion and content of the attached media item. The attached media item may be of various types. Examples of media items include video files, audio files, image files, resource locators, and application files. The embodiments, however are not limited to these examples. | 03-05-2009 |
20090061825 | TECHNIQUES FOR GROUP MESSAGING ON A MOBILE COMPUTING DEVICE - Techniques for group messaging on a mobile computing device are described. An apparatus may comprise a message server to communicate messages between multiple mobile computing devices. The message server may have a group message management module to establish a group messaging session between the multiple mobile computing devices. The group message management module may have a group generating module to receive a message with a group message indicator and identifying information for multiple mobile computing devices within the message. The group generating module may form a message group to communicate messages from any one of the mobile computing devices to all of the mobile computing devices for the group messaging session. Other embodiments are described and claimed. | 03-05-2009 |
20090117942 | MESSAGE ADDRESSING TECHNIQUES FOR A MOBILE COMPUTING DEVICE - Various embodiments are directed to improved message addressing techniques. In one embodiment, a computing device may comprise a messaging client arranged to receive an input sequence of alphabetic or alphanumeric characters as a destination of an outbound message. The messaging client may recognize that the input sequence represents a mnemonic short code and may automatically generate a common short code comprising a sequence of numeric digits associated with the mnemonic short code. The messaging client may display both the input sequence comprising the mnemonic short code and the common short code and enable the outbound message to be sent using the common short code as the destination. Other embodiments are described and claimed. | 05-07-2009 |
20150195241 | SYSTEM, METHOD AND TECHNIQUE FOR ENABLING USERS TO INTERACT WITH ADDRESS FILEDS OF MESSAGING APPLICATIONS - An example system includes a main processor operable in a normal mode or a trusted mode, the main processor having an embedded diagnostic trusted code executable in the trusted mode; a secure memory accessible by the main processor when the main processor is in the trusted mode and inaccessible to the main processor when the main processor is in the normal mode, wherein execution of the embedded diagnostic trusted code causes the main processor to write diagnostic information to the secure memory; and a monitor processor having access to the secure memory to analyze the diagnostic information to determine a state of the main processor. | 07-09-2015 |
Richard J. Donald, San Jose, CA US
Patent application number | Description | Published |
---|---|---|
20100048231 | Handheld Threading - The present invention determines which messages to display in message threads to a user. An electronic communication device receives and stores numerous SMS messages transported through an SMS network, but the SMS messages are sent without explicit linking information such as a previous message or subject line. A threading module applies threading rules to determine which messages to correlate into an SMS message thread through implicit link information. The threading rules thread outgoing messages sent in response to an incoming message from a user, or incoming messages where a previous outgoing message was sent to the user. An SMS application displays threads in a user interface and indicates messages threads with an icon in one view, and displays an expanded message thread in another view. | 02-25-2010 |
Rick Donald, Sunnyvale, CA US
Patent application number | Description | Published |
---|---|---|
20090037509 | WIDGET DISCOVERY IN COMPUTING DEVICES - A system and a method are disclosed for discovering widgets for computing devices. A computing device parses data to identify rich content. The computing device searches for widgets supporting the identified rich content in a remote server and retrieves a widget supporting the identified rich content. The computing device executes the widget to process the rich content. | 02-05-2009 |
Robert Andrew Donald, Riverside, CT US
Patent application number | Description | Published |
---|---|---|
20140039017 | THERAPEUTIC COMBINATION - This invention relates to pharmaceutical combinations of amlodipine or a pharmaceutically acceptable acid addition salt thereof and atorvastatin or a pharmaceutically acceptable salt thereof, kits containing such combinations and methods of using such combinations to treat subjects suffering from angina pectoris, atherosclerosis, combined hypertension and hyperlipidemia and to treat subjects presenting with symptoms of cardiac risk, including humans. This invention also relates to additive and synergistic combinations of amlodipine and atorvastatin whereby those synergistic combinations are useful in treating subjects suffering from angina pectoris, atherosclerosis, combined hypertension and hyperlipidemia and those subjects presenting with symptoms of cardiac risk, including humans. | 02-06-2014 |
Robert G.k. Donald, South Orange, NJ US
Patent application number | Description | Published |
---|---|---|
20080280313 | Coccidian Parasite Casein Kinase I as a Chemotherapeutic Target for Antiprotozoal Agents - Isolated nucleic acid molecules encoding coccidian casein kinase I, CKI, enzymes from the species | 11-13-2008 |
Robert G. K. Donald, South Orange, NJ US
Patent application number | Description | Published |
---|---|---|
20120269841 | COMPOSITIONS RELATING TO A MUTANT CLOSTRIDIUM DIFFICILE TOXIN AND METHODS THEREOF - In one aspect, the invention relates to an immunogenic composition that includes a mutant | 10-25-2012 |
20130244307 | COMPOSITIONS RELATING TO A MUTANT CLOSTRIDIUM DIFFICILE TOXIN AND METHODS THEREOF - In one aspect, the invention relates to an immunogenic composition that includes a mutant | 09-19-2013 |
20130330371 | COMPOSITIONS RELATING TO A MUTANT CLOSTRIDIUM DIFFICILE TOXIN AND METHODS THEREOF - In one aspect, the invention relates to an immunogenic composition that includes a mutant | 12-12-2013 |
20150125927 | COMPOSITIONS RELATING TO A MUTANT CLOSTRIDIUM DIFFICILE TOXIN AND METHODS THEREOF - In one aspect, the invention relates to an immunogenic composition that includes a mutant | 05-07-2015 |
20150291940 | COMPOSITIONS AND METHODS RELATING TO A MUTANT CLOSTRIDIUM DIFFICILE TOXIN - In one aspect, the invention relates to an immunogenic composition that includes a mutant | 10-15-2015 |
20150307563 | COMPOSITIONS RELATING TO A MUTANT CLOSTRIDIUM DIFFICILE TOXIN AND METHODS THEREOF - In one aspect, the invention relates to an immunogenic composition that includes a mutant | 10-29-2015 |
20160002361 | SACCHARIDES AND USES THEREOF - The invention relates to novel saccharides and uses thereof. In one aspect, the invention relates to a saccharide having a legionaminic acid moiety, a N-acetylgalactosamine moiety, a galactose moiety, and a glucose moiety. In another aspect, the invention relates to a saccharide having an altruronic acid moiety, a fucose moiety, and a glucose moiety. In yet another aspect, the invention relates to a saccharide having a repeating unit of a glycerol phosphate moiety and a glucose moiety, wherein the saccharide is from | 01-07-2016 |
Robert J. Donald, Midland, MI US
Patent application number | Description | Published |
---|---|---|
20090173441 | METHOD FOR JOINING PIPING SYSTEMS AND PIPING TO EQUIPMENT, FIXTURES, DEVICES, STRUCTURES, AND APPLIANCES - A method to join pipe is disclosed using a curable one or two part adhesive composition comprising an effective amount of a boron containing initiator compound such as an organoborate, a stabilized organoborane complex, or combinations thereof; one or more monomers, oligomers, polymers or mixtures thereof having olefinic unsaturation which is capable of polymerization by free radical polymerization; and optionally a decomplexing agent. | 07-09-2009 |
20090189321 | Thermoplastic composition and use for large parison blow molding applications - A polymeric blend composition, and method of using same for large parison blow molding applications, comprising greater than about 50 parts by weight of a carbonate polymer component (e.g., a branched polycarbonate having a weight average molecular weight (M | 07-30-2009 |
20100316823 | THERMOPLASTIC COMPOSITION AND USE FOR LARGE PARISON BLOW MOLDING APPLICATIONS - A polymeric blend composition, and method of using same for large parison blow molding applications, comprising greater than about 50 parts by weight of a carbonate polymer component (e.g., a branched polycarbonate having a weight average molecular weight (M | 12-16-2010 |
20110256333 | Polypropylene Compositions - A mineral-filled, polypropylene composition comprises (i) a coupled, impact propylene polymer, and (ii) at least 0.5 weight percent (wt %) based on the weight of the composition of at least one of calcium carbonate and talc. The compositions are useful in the manufacture of three-layer pipe comprising (A) a first or outer non-foam layer; (B) a second or middle foam layer; and (C) a third or inner non-foam layer. | 10-20-2011 |
Scott Donald, Spring, TX US
Patent application number | Description | Published |
---|---|---|
20160123096 | IN-SITU MINING OF ORES FROM SUBSURFACE FORMATIONS - An in situ method of mining is disclosed. In one non-limiting embodiment, the method includes: defining an ore volume; drilling a large number of vertical boreholes; forming lateral boreholes from at least some of the vertical boreholes; transporting the ore cut during drilling of the vertical and lateral boreholes to a surface location; and separating the ore received at the surface from other materials. Additional ore may be extracted fracturing and/or leaching the formation surrounding the drilled boreholes. The residual ore at the surface may be disposed by pumping it into already drilled boreholes or underground storage facilities. | 05-05-2016 |
Scott F. Donald, Spring, TX US
Patent application number | Description | Published |
---|---|---|
20140332285 | FORMATION-ENGAGING ELEMENT PLACEMENT ON EARTH-BORING TOOLS AND RELATED METHODS - Earth-boring tools include a cutting element positioned on a drill bit body at a radial distance from a longitudinal axis thereof. At least two formation-engaging elements are positioned at the same radial distance from the longitudinal axis as the cutting element. The formation-engaging elements are recessed from cutting profile of the cutting element by a distance within about 10% of d, wherein d=(α*x)/(1800*y), where α is an angle between the formation-engaging element and the cutting element, x is a rate of penetration of the drill bit body, and y is a rotation speed of the drill bit body. Additional earth-boring tools include at least one cutting element and at least two formation-engaging elements recessed from a cutting profile of the at least one cutting element at a common angle. Methods relate to forming such earth-boring tools. | 11-13-2014 |
20150287150 | SYSTEMS AND METHODS FOR EARTH-BORING ROTARY DRILL BIT SELECTION - Systems and methods may be used to select a drill bit design for an earth-boring rotary drill bit for use in a particular drilling application. The systems may include a computer server, and a remote device configured to communicate with the computer server through a network. The computer server may include a database including information relating to normalized scores for a plurality of drill bit responses for a plurality of differing drill bit designs. The computer server may receive information from the at least one remote device, to select one or more potential drill bit designs from the at least one database based on the information, and to transmit information relating to the selected one or more potential drill bit designs to the remote device. Such systems may be used in methods of selecting drill bit designs for earth-boring rotary drill bits for use in respective drilling applications. | 10-08-2015 |
20160060964 | EARTH-BORING TOOLS WITH EXTENDED CUTTING FEATURES AND RELATED METHODS - A superabrasive-impregnated earth-boring rotary drill bit includes cutting features extending outwardly from a bit body in a nose region of the drill bit. The cutting features comprise a composite material including superabrasive particles embedded within a matrix material. The cutting features extend from an outer surface of the bit body by a relatively high average distance. Methods of forming a superabrasive-impregnated earth-boring rotary drill bit include the formation of cutting features that extend outwardly from a bit body of a drill bit in a nose region of the drill bit. The cutting features are formed to comprise a particle-matrix composite material that includes superabrasive particles embedded within a matrix material. The cutting features are further formed such that they extend from the outer surface of the bit body by a relatively high average distance. | 03-03-2016 |
Scott F. Donald, The Woodlands, TX US
Patent application number | Description | Published |
---|---|---|
20100187011 | CUTTING STRUCTURES FOR CASING COMPONENT DRILLOUT AND EARTH-BORING DRILL BITS INCLUDING SAME - An earth-boring tool includes a bit body having a face on which two different types of cutters are disposed, the first type being cutting elements suitable for drilling at least one subterranean formation and the second type suitable for drilling through at least one elastomeric component of a casing string, as well as a casing shoe and cement. Methods of drilling with an earth-boring tool include engaging and drilling an elastomeric component using at least one abrasive cutting structure. | 07-29-2010 |
20130118813 | CUTTING ELEMENTS HAVING LATERALLY ELONGATED SHAPES FOR USE WITH EARTH-BORING TOOLS, EARTH-BORING TOOLS INCLUDING SUCH CUTTING ELEMENTS, AND RELATED METHODS - A cutting element for an earth-boring tool includes a volume of superabrasive material on a substrate. The cutting element has an elongated shape in a lateral dimension parallel to a front cutting face of the cutting element, and has a maximum lateral width in a first direction parallel to the front cutting face of the cutting element and a maximum lateral length in a second perpendicular direction parallel to the front cutting face of the cutting element. The maximum lateral length is significantly greater than the maximum lateral width. An earth-boring tool includes one or more such cutting elements mounted to a body of the earth-boring tool. A method of forming such an earth-boring tool includes selecting at least one such cutting element and mounting the cutting element to a body of an earth-boring tool. | 05-16-2013 |
20130186694 | SUPERABRASIVE-IMPREGNATED EARTH-BORING TOOLS WITH EXTENDED FEATURES AND AGGRESSIVE COMPOSITIONS, AND RELATED METHODS - A superabrasive-impregnated earth-boring rotary drill bit includes cutting features extending outwardly from a bit body in a nose region of the drill bit. The cutting features comprise a composite material including superabrasive particles embedded within a matrix material. The cutting features extend from the outer surface of the bit body by a relatively high average distance. Methods of forming a superabrasive-impregnated earth-boring rotary drill bit include the formation of cutting features that extend outwardly from a bit body of a drill bit in a nose region of the drill bit. The cutting features are formed to comprise a particle-matrix composite material that includes superabrasive particles embedded within a matrix material. The cutting features are further formed such that they extend from the outer surface of the bit body by a relatively high average distance. | 07-25-2013 |
Sean Donald, Spring, TX US
Patent application number | Description | Published |
---|---|---|
20150367483 | APPARATUS AND METHODS FOR HIGH PRESSURE LEACHING OF POLYCRYSTALLINE DIAMOND CUTTER ELEMENTS - A method for leaching a PCD table for a cutter element includes (a) positioning a PCD table within a leaching chamber. The method also includes (b) submerging the PCD table in an acid within the leaching chamber. In addition, the method includes (c) sealing the leaching chamber. Further, the method includes (d) increasing the pressure within the leaching chamber to a pressure greater than or equal to 20,000 psi after (c). | 12-24-2015 |
Shannon Donald, Baltimore, MD US
Patent application number | Description | Published |
---|---|---|
20120306154 | Board Game Apparatus - The present invention features a game apparatus having a game board having game spaces and game pieces. The apparatus comprises fabulous five game pieces and blank game pieces with indicia on one side identifying the game piece is a traveler. Only a traveler can move in a forwards and backwards direction on the game board in one or two game spaces. The game pieces move in a diagonal motion two diagonal game spaces or a ricochet motion, which is in a curved motion to one game space in the first column and then to a second game space in the second column. The player who cannot move or the player who has no remaining game pieces on the board loses the game. | 12-06-2012 |
Stephen D. Donald, Bowie, MD US
Patent application number | Description | Published |
---|---|---|
20080263009 | System and method for sharing of search query information across organizational boundaries - Disclosed is a method and system for capturing and reporting information relating to an organization's queries, such as Internet search queries generated by particular groups within an organization, and making such information available to others to support various decisions organizations must make. The search activity of search-level users may be constantly tracked, and search event data records (including query terms and an identification of the search-level user) are collected and analyzed. An analytics engine receives and analyzes the search event data and determines when predefined organization-specific relationships exist between queries of distinct users. When such a relationship is identified, a notification message or alert may be generated indicating the existence of such relationship, and directed to a person in the organization other than the search-level users whose queries were found as relating to one another, thus allowing such person receiving the notification to take action in response to the related activity. | 10-23-2008 |
Steven Donald, Lyons, NY US
Patent application number | Description | Published |
---|---|---|
20100054784 | FUSERS, PRINTING APPARATUSES AND METHODS OF FUSING TONER ON MEDIA - Fusers, printing apparatuses and methods of fusing toner on media are disclosed. An embodiment of a fuser for heating media includes a fuser roll including an outer portion having a first outer surface; a voltage source connected to the outer portion and adapted to supply voltage to the outer portion to heat the first outer surface; a pressure roll having a second outer surface; and a nip between the first and second outer surfaces. The first and second outer surfaces are adapted to contact a medium at the nip. | 03-04-2010 |
Steven T. Donald, Agua Dulce, TX US
Patent application number | Description | Published |
---|---|---|
20100158726 | Plunger Pump - A pump system according on one or more aspects of another embodiment of the present disclosure comprises a pair of plunger pumps disposed in a back-to-back assembly having a width that is less than about 102 inches, wherein each pump comprises a zero offset and at least a six inch stroke. | 06-24-2010 |
20110239856 | Plunger Pump Lubrication System and Method - A system and method for lubricating a packing gland of a positive displacement plunger pump. The system includes a pressure regulated lubricant discharge from the packing gland. The pressure regulated lubricant discharge maintains a positive pressure in the packing gland to resist unloading of the packing. | 10-06-2011 |