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| 20100046576 | METHOD FOR PERFORMING ULTRASONIC TESTING - Methods of performing ultrasonic testing are disclosed, comprising the step of determining a temperature gradient of an ultrasonic wedge. In one embodiment of the invention, the method further comprises the steps of determining a sound velocity gradient of the ultrasonic wedge to determine the time it takes for sound waves emanating from a plurality of ultrasonic transducer elements attached to the ultrasonic wedge to reach a point of interest within a test object, and firing each of the ultrasonic transducer elements in a timed sequence based on the times such that sound waves from each of the ultrasonic transducer elements reach the point of interest at the same time. In other embodiments of the invention, the total attenuation and acoustic impedance of a sound wave traveling through the ultrasonic wedge is determined to adjust the amplitude of the sound wave such that the sound wave has sufficient amplitude to perform the ultrasonic testing. | 02-25-2010 |
| 20100275692 | APPARATUS AND SYSTEM FOR MEASURING MATERIAL THICKNESS - An apparatus and system for measuring material thickness of a test object. In one embodiment, the apparatus can include a measurement probe that can have a plurality of transducer elements that can include transmitter elements and receiver elements arranged, respectively, in on a first side and a second side of a gap. The first side and the second side can form a scan area with at least one active group that can have at least one transmitter element and at least one receiver element, which can be separated from the transmitter element in a spaced relationship. | 11-04-2010 |
| 20110076863 | APPARATUS FOR CONNECTING A MULTI-CONDUCTOR CABLE TO A PIN GRID ARRAY CONNECTOR - An apparatus for connecting a multi-conductor cable of a first device to a pin grid array connector of a second device, wherein said apparatus comprises a first printed circuit board (PCB) for terminating the conductors of the cable, which are connected to a first PCB surface mounted connector mounted on the first PCB. The first PCB surface mounted connector is mated with a second PCB surface mounted connector mounted on a second PCB, on which a PCB surface mounted socket grid array is also mounted for mating to the pin grid array connector of the second device. This apparatus allows the same (i.e., standardized) multi-conductor cable with the same first PCB and the same first PCB surface mounted connector to be used regardless of what style connector is used by the second device. | 03-31-2011 |
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| 20130178523 | ANTI-CANCER COMPOSITIONS AND METHODS - Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. | 07-11-2013 |
| 20130184339 | ANTI-CANCER COMPOSITIONS AND METHODS - Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. | 07-18-2013 |
| 20130184340 | ANTI-CANCER COMPOSITIONS AND METHODS - Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. | 07-18-2013 |
| 20130253052 | ANTI-CANCER COMPOSITIONS AND METHODS - Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. | 09-26-2013 |
| 20140212475 | ANTI-CANCER COMPOSITIONS AND METHODS - Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor. | 07-31-2014 |
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| 20100179103 | CURCUMIN CYCLODEXTRIN COMBINATION FOR PREVENTING OR TREATING VARIOUS DISEASES - Curcumin has shown anti-inflammatory and anti-angiogenic properties that could be useful in treating various diseases such as those of rheumatology and oncology. However, curcumin is very poorly absorbed and has a very low bioavailability. This patent describes a method of increasing the delivery of curcumin by complexing it with cyclodextrins. Cyclodextrins are well known in the food industry and have been used to carry other drugs to increase bioavailability. The new combination of cyclodextrins and curcumin has been tested in pre-clinical inflammation models where it has demonstrated efficacy superior to both the positive control and curcumin. | 07-15-2010 |
| 20110263537 | CO-ADMINISTRATION OF STEROIDS AND ZOLEDRONIC ACID TO PREVENT AND TREAT SIDE EFFECTS FROM ZOLEDRONIC ACID INFUSION - Zoledronic Acid is used for treatment of hypercalcemia of malignancy, for the treatment of bone metastasis associated with malignancies such as prostate and breast cancer, for the prevention of and treatment of osteoporosis and for the treatment of Paget's disease. Administration of Zoledronic Acid is complicated by what is described as “post-dosing syndrome” (PDS) and osteonecrosis of the jaw (ONJ). Inflammation may be the cause of these side effects, which could be decreased by the co-administration of steroids. This application is a method of use patent for the co-administration of steroids (oral, IV, IM, rectal, or by inhalation) with Zoledronic Acid and a composition of matter patent for mixing Methyl Prednisolone with Zoledronic Acid for infusion. | 10-27-2011 |
| 20110275645 | Small Molecules for Inhibition of Protein Kinases - The invention provides compounds that inhibit protein kinases, prodrugs of the compounds, intermediates and methods of synthesizing the compounds and/or prodrugs, pharmaceutical compositions including the compounds and/or prodrugs and methods of using the compounds and/or prodrugs in a variety of contexts, including, for example, in the treatment and/or prevention of various diseases that are responsive to protein kinase inhibition and/or that are mediated, at least in part, by inappropriate kinase activity. | 11-10-2011 |
| 20120315235 | EMU OIL IN COMBINATION WITH OTHER ACTIVE INGREDIENTS FOR TREATING SKIN IMPERFECTIONS - Compositions comprising emu oil as a vehicle for the delivery of other active ingredients for the treatment of cosmetic and other skin imperfections such as acne, wrinkles, and hair loss are disclosed. Methods of treating cosmetic and other skin imperfections using the compositions are also disclosed. | 12-13-2012 |
| 20130058980 | SMALL MOLECULE INHIBITORS OF PROTEIN KINASES - Compounds that modulate, for example, that inhibit, syk kinase, and, optionally other kinases. The compounds can be used to treat a variety of disorders, including inflammatory disorders and autoimmune disorders. | 03-07-2013 |
| Patent application number | Description | Published |
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| 20110275645 | Small Molecules for Inhibition of Protein Kinases - The invention provides compounds that inhibit protein kinases, prodrugs of the compounds, intermediates and methods of synthesizing the compounds and/or prodrugs, pharmaceutical compositions including the compounds and/or prodrugs and methods of using the compounds and/or prodrugs in a variety of contexts, including, for example, in the treatment and/or prevention of various diseases that are responsive to protein kinase inhibition and/or that are mediated, at least in part, by inappropriate kinase activity. | 11-10-2011 |
| 20130058980 | SMALL MOLECULE INHIBITORS OF PROTEIN KINASES - Compounds that modulate, for example, that inhibit, syk kinase, and, optionally other kinases. The compounds can be used to treat a variety of disorders, including inflammatory disorders and autoimmune disorders. | 03-07-2013 |
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| 20100003506 | COATED ARTICLES DEMONSTRATING HEAT REDUCTION AND NOISE REDUCTION PROPERTIES - Coated articles are provided comprising:
| 01-07-2010 |
| 20100004353 | WATERBORNE FILM-FORMING COMPOSITIONS HAVING HEAT REFLECTIVE PROPERTIES - Curable compositions are provided comprising:
| 01-07-2010 |
| 20100004369 | LOW DENSITY VISCOELASTIC COMPOSITION HAVING DAMPING PROPERTIES - Curable compositions are provided comprising:
| 01-07-2010 |
| 20100258371 | WATERBORNE FILM-FORMING COMPOSITIONS HAVING HEAT REFLECTIVE PROPERTIES - A heat reflective system in which a curable composition is deposited and cured onto a substrate, wherein the curable composition comprises: (a) a resinous binder comprising a polyamideimide, a polyepoxide and/or a polysiloxane; and (b) a metallic reflective pigment. After application to a surface of a substrate and after curing, when the coated surface is exposed to a heat source having a temperature up to 390° C. at a distance of at least ½ inch (1.27 cm), the reverse side of the substrate is at least 20 Celsius degrees lower than the temperature of the reverse side of a similar substrate without the curable film-forming composition. | 10-14-2010 |
| 20110037013 | COATINGS COMPRISING ITACONATE LATEX PARTICLES AND METHODS FOR USING THE SAME - Coatings comprising a latex particle comprising the reaction product of itaconic acid/anhydride and a monoalcohol, a monoepoxide, a monoamine or mixtures thereof are disclosed. Methods for using such coatings, particularly for inhibiting sound and/or vibration transmission through a substrate, are also disclosed. | 02-17-2011 |
| 20120128499 | STRUCTURAL ADHESIVE COMPOSITIONS - Disclosed herein are 2K structural adhesive compositions comprising (a) a first component comprising (i) an epoxy-adduct formed as a reaction product of reactants comprising a first epoxy compound, a polyol, and an anhydride and/or a diacid; and (ii) a second epoxy compound; and (b) a second component that reacts with the first component. In one embodiment, the second component is an amine compound. These adhesives may be used to bond together substrate materials such as two half shells of wind turbine blades. | 05-24-2012 |
| 20120129980 | STRUCTURAL ADHESIVE COMPOSITIONS - Disclosed herein are compositions including (a) a first component comprising (1) an epoxy-adduct that is the reaction product of reactants comprising a first epoxy compound, a polyol, and an anhydride and/or a diacid and (2) a second epoxy compound; (b) rubber particles having a core/shell structure and/or graphenic carbon particles; and (c) a second component that chemically reacts with the first component at ambient or slightly thermal conditions. Also disclosed herein are compositions including (a) an epoxy-capped flexibilizer; (b) a heat-activated latent curing agent; and optionally (c) rubber particles having a core/shell structure and/or graphenic carbon particles; (d) an epoxy/CTBN adduct; and/or (e) an epoxy/dimer acid adduct. | 05-24-2012 |
| 20120211160 | ADHESIVE COMPOSITIONS CONTAINING GRAPHENIC CARBON PARTICLES - Disclosed herein are adhesive compositions comprising (a) a first component; (b) a second component that chemically reacts with said first component; and (c) graphenic carbon particles having a compressed density of 0.9 or less. Disclosed herein are associated methods for forming the adhesive compositions and applying the adhesive compositions to a substrate to form a bonded substrate. | 08-23-2012 |
| 20140150970 | STRUCTURAL ADHESIVE COMPOSITIONS - Disclosed herein are compositions including (a) a first component comprising (1) an epoxy-adduct that is the reaction product of reactants comprising a first epoxy compound, a polyol, and an anhydride and/or a diacid and (2) a second epoxy compound; (b) rubber particles having a core/shell structure and/or graphenic carbon particles; and (c) a second component that chemically reacts with the first component at ambient or slightly thermal conditions. Also disclosed herein are compositions including (a) an epoxy-capped flexibilizer; (b) a heat-activated latent curing agent; and optionally (c) rubber particles having a core/shell structure and/or graphenic carbon particles; (d) an epoxy/CTBN adduct; and/or (e) an epoxy/dimer acid adduct. The heat-activated latent curing agent may include at least one reaction product of reactants including an epoxy compound and an amine and/or an alkaloid. | 06-05-2014 |
| 20140299270 | ADHESIVE COMPOSITIONS CONTAINING GRAPHENIC CARBON PARTICLES - Disclosed herein are adhesive compositions comprising (a) a first component; (b) a second component that chemically reacts with said first component; and (c) graphenic carbon particles having an oxygen content of no more than 2 atomic weight percent. Disclosed herein are associated methods for forming the adhesive compositions and applying the adhesive compositions to a substrate to form a bonded substrate. | 10-09-2014 |
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| 20080313267 | OPTIMIZE WEB SERVICE INTERACTIONS VIA A DOWNLOADABLE CUSTOM PARSER - A method, system and computer program product for optimizing web service interactions. A server receives a service request from a client, where the service request includes information that is used by the server to provide a customized parser to the client that allows optimal web service interactions. Upon the server providing a link to the client to download this customized parser, the client downloads the parser and embeds the parser into its runtime environment. The parser in the client is then able to receive and transmit communications from and to the server, respectively, in a most efficient manner. For example, the parser may reduce the size of the XML message size more considerably than compression algorithms. In another example, if the client and server communicate in different languages, the parser may translate the messages between the client and server so that the messages are understandable. | 12-18-2008 |
| 20090138545 | ASYNCHRONOUS RESPONSE PROCESSING IN A WEB BASED REQUEST-RESPONSE COMPUTING SYSTEM - Embodiments of the present invention address deficiencies of the art in respect to asynchronous web based request-response handling and provide a method, system and computer program product for asynchronous response handling in a web based request-response computing system. In an embodiment of the invention, a method for asynchronous response handling in a web based request-response computing system can be provided. The method can include inserting an address of an intermediate response server in a request, transmitting the request to a target processing server separate from the intermediate response server, and polling the intermediate response server for a response | 05-28-2009 |
