De Laat
Adrianus Marinus Maria De Laat, Breda NL
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20120183646 | CARBOHYDRATE-ENRICHED PLANT PULP COMPOSITION - The invention pertains to a plant or vegetable pulp composition comprising: a) plant or vegetable pulp comprising 5-30 wt % cell wall materials comprising or consisting of cellulose, hemicellulose, lignin and/or pectin, and/or fragments and/or hydrolysates thereof, wherein said pulp is obtained by disrupting plant or vegetable cell membranes and removing at least part of the intracellular content; b) 45-85 wt % of one or more water-soluble carbohydrate(s) selected from the group consisting of inulin, oligofructose, fructo-oligosaccharide, galacto-oligosaccharide, glucose, maltose, maltodextrins, polydextrose, sucrose, fructose, lactose, isomaltulose and polyols, and/or combinations thereof; and c) 5-25 wt % water, all numbers based on total weight of said composition. The invention also pertains to the method of preparing such a composition, and the use in (human) food applications. | 07-19-2012 |
Antonius Wilhelmus Maria De Laat, Eindhoven NL
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20160084476 | ENCAPSULATED QUANTUM DOTS IN POROUS PARTICLES - The invention provides a process for the production of a (particulate) luminescent material comprising particles, especially substantially spherical particles, having a porous inorganic material core with pores, especially macro pores, which are at least partly filled with a polymeric material with luminescent quantum dots embedded therein, wherein the process comprises (i) impregnating the particles of a particulate porous inorganic material with pores with a first liquid (“ink”) comprising the luminescent quantum dots and a curable or polymerizable precursor of the polymeric material, to provide pores that are at least partly filled with said luminescent quantum dots and curable or polymerizable precursor; and (ii) curing or polymerizing the curable or polymerizable precursor within pores of the porous material, as well as a product obtainable thereby. | 03-24-2016 |
Antonius Wilhelmus Maria De Laat, Den Dungen NL
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20120283669 | PUNCTAL PLUGS FOR CONTROLLED RELEASE OF THERAPEUTIC AGENTS - Lacrimal inserts such as punctal plugs may be utilized for delivery of medication to the eye. The plug includes a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of the eyelid. The plug may contain a core, or reservoir, at least partially within the body portion comprising a therapeutic agent that is configured for controlled, pulsatile release into the eye. | 11-08-2012 |
20130197341 | DISPOSABLE ELECTRODE FOR ELECTRO-STIMULATION - An electrode configured to provide electrical contact with a subject's skin and includes a conductive layer and a gel layer. The conductive layer spreads current and transmits electrical signals to and/or receives electrical signals from the subject's skin and has a first conductive surface through which electrical signals are transmitted to and/or received from the subject's skin. The first conductive surface is on a side of the conductive layer that faces toward the subject's skin if the electrode is installed on the subject. The gel layer is formed on the same side of the conductive layer as the first conductive surface. The gel layer has a first interface surface that directly contacts the subject's skin if the electrode is installed on the subject, and to conduct electrical signals between the subject's skin and the first conductive surface. The first interface surface has a surface area larger than that of the first conductive surface. | 08-01-2013 |
20140148887 | ELECTRODE APPARATUS - An electrode apparatus may be configured Electrode to provide electro-stimulation. The apparatus may include assembly a current spreader and a spongeless volume disposed adjacent to the current spreader. The current spreader may be configured to spatially distribute electrical current across a stimulation area of a subject's skin. The spongeless volume may be configured to carry liquid gel or other fluent conductive substance that is configured to conduct electrical current between the current spreader and the stimulation area of the subject's skin to provide electro-stimulation. | 05-29-2014 |
20140321609 | SCINTILLATOR PACK COMPRISING AN X-RAY ABSORBING ENCAPSULATION AND X-RAY DETECTOR ARRAY COMPRISING SUCH SCINTILLATOR PACK - A scintillator pack ( | 10-30-2014 |
20150144839 | OPTICAL COMPOSITION - An optical composition is provided, comprising: —a polysilsesquioxane comprising repeating units of the formula [R—SiO | 05-28-2015 |
Bas H. De Laat, Maastricht NL
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20150118691 | SIMULTANEOUS MEASUREMENT OF THROMBIN GENERATION AND CLOT STRENGTH IN PLASMA AND WHOLE BLOOD - A method for the simultaneous measurement of proteolylic enzyme generation and clot strength in plasma or whole blood or any appropriate biological sample derived from blood. The measurement method encompasses the use of a detectable substrate which includes a moiety that can be released upon reaction with the targeted proteolytic enzyme, and elements for measurement of an increase in viscosity of clot strength. | 04-30-2015 |
Cornelis Wilhelmus Jacobus De Laat, Etten-Leur NL
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20090252589 | Apparatus and method for handling pipe - An apparatus for handling pipes, the apparatus, in certain aspects, having a body having a tapered surface and at least a first slip and a second slip slidable on the tapered surface, a slip actuator for setting said at least first slip and said second slip, said first slip and said second slip having interengaging elements such that upon actuation of said slip actuator, said first slip is set and said second slip is set by the interengaging elements transferring setting force from the slip actuator through said first slip to said second slip; and methods for using such an apparatus. | 10-08-2009 |
Dennis De Laat, Hilversum NL
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20130007890 | METHOD AND SYSTEM FOR DETECTING VIOLATION OF INTELLECTUAL PROPERTY RIGHTS OF A DIGITAL FILE - A computer-based method and system for detecting violation of intellectual property rights of a digital file, comprising, in a distribution channel, digitally sending or streaming the file from a sending party to a receiving party, adding a watermark to the digital file at the sending party prior to sending or streaming the file, wherein the watermark comprises an identifier of the sending and receiving party(s), as well as a unique file ID. In one embodiment, the party is informed about user and/or customer behavior, and can take precautions. | 01-03-2013 |
Jules Martinus Adrianus Gerardus De Laat, Tilburg NL
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20160091217 | SYSTEMS AND METHODS FOR MANAGING ENVIRONMENTAL CONDITIONS - Disclosed are systems and methods for adjusting environmental conditions based on automatically and manually generated requests. A commissioned unit comprising at least one IP luminaire ( | 03-31-2016 |
20160095188 | SYSTEMS AND METHODS FOR MANAGING ENVIRONMENTAL CONDITIONS - Disclosed are systems and methods for adjusting environmental conditions within a physical structure comprising a plurality of linked commissioned units. One or more occupancy sensors ( | 03-31-2016 |
Marc De Laat, Amsterdam NL
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20130007890 | METHOD AND SYSTEM FOR DETECTING VIOLATION OF INTELLECTUAL PROPERTY RIGHTS OF A DIGITAL FILE - A computer-based method and system for detecting violation of intellectual property rights of a digital file, comprising, in a distribution channel, digitally sending or streaming the file from a sending party to a receiving party, adding a watermark to the digital file at the sending party prior to sending or streaming the file, wherein the watermark comprises an identifier of the sending and receiving party(s), as well as a unique file ID. In one embodiment, the party is informed about user and/or customer behavior, and can take precautions. | 01-03-2013 |
Martijn H.c. De Laat, Veldhoven NL
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20140230380 | Apparatus for Packaging an Object with a Tubular Film - An apparatus for packaging an object with a tubular film, includes: a main frame, a stretch frame for stretching the tubular film and to applying the tubular film to the object, and a top frame having a feeding device for delivering a tubular film from a film magazine to the stretch frame and having a cutting device to cut the tubular film to a predetermined length. The top frame is moveable at the main frame between a working position and a maintenance position. In the maintenance position the top frame is located outside the work space. | 08-21-2014 |
Maurice Martinus De Laat, Budel NL
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20120213527 | OPTOELECTRONIC DEVICE FOR BIDIRECTIONALLY TRANSPORTING INFORMATION THROUGH OPTICAL FIBERS AND METHOD OF MANUFACTURING SUCH A DEVICE - An optoelectronic device for bidirectionally transporting information through glass fibers between logically distributed users and a central station by means of transceivers of said central station. In particular, a set of several glass fibers ( | 08-23-2012 |
20130142488 | MULTIPURPOSE FIBER TERMINATION UNIT - The NTU receiving structure ( | 06-06-2013 |
20130156430 | DEVICE FOR USING A BROADBAND NETWORK AT A CUSTOMER'S PREMISES, METHOD OF OPERATING SUCH A DEVICE AND BROADBAND NETWORK SYSTEM UTILIZING SUCH A DEVICE - The invention relates to a piece of customer premises equipment (CPE) comprising a physical connector ( | 06-20-2013 |
20130343763 | DEVICE FOR USE ON THE LOCATION OF A CUSTOMER OF A BROADBAND NETWORK SYSTEM, BROADBAND NETWORK SYSTEM USING SUCH A DEVICE AND METHOD FOR CONSTRUCTING SUCH A DEVICE - The invention is particularly related to an optoelectronic device ( | 12-26-2013 |
Walterus Theodorus Franciscus Maria De Laat, Eindhoven NL
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20090001493 | ELECTRONIC IMAGING DEVICE - An electronic imaging device includes a base layer containing electrical functional circuitry, the base layer having a first side for interconnection of the circuitry and a second side which serves as a photo-detection side. The second side has exposed photosensitive electrical elements arranged in the base layer. Spacers of a predetermined height are provided adjacent to said second side. The spacers can advantageously be used for gaining control over the tolerance of a desired distance between a lens of a lens system and said photo-detection side. Thus, individual focusing of the lens system of each imager device after completion of production is no longer needed. Moreover, an air gap that improves the performance of the micro-lenses may be formed. | 01-01-2009 |
Wilhelmus Johannes Maria De Laat, Heeswijk-Dinther NL
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20090170025 | LITHOGRAPHIC METHOD AND CARRIER SUBSTRATE - A carrier substrate is provided with a layer of PDMS and curing agent on one side of the carrier substrate. The PDMS and curing agent can be arranged to receive and adhere to a lithographic substrate. The carrier substrate can be dimensioned such that the combined carrier substrate and lithographic substrate may be handled by a conventional lithographic apparatus. | 07-02-2009 |
20120281192 | LITHOGRAPHIC APPARATUS AND METHOD - A method of obtaining information indicative of the topography of a surface of a flexible substrate, the method including directing a beam of radiation at the surface of the flexible substrate; and detecting changes in intensity distribution, or angle of reflection, of the beam of radiation after the beam of radiation has been reflected from the surface of the substrate to obtain information indicative of the topography of the surface of the flexible substrate. | 11-08-2012 |
Wilhelmus Nicolaas Gerardus Maria De Laat, Den Haag NL
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20160022198 | Vaginal Drug Delivery and/or Diagnostic System - The present invention relates to a vaginal drug delivery and/or diagnostic system, which is connected to a positioning member configured for placement within the vagina. The system comprises an electronic capsule comprising a drug reservoir and means for dispensing the drug from the reservoir into the vagina. The positioning member is for example eight-shaped, pear-shaped or dolphin-shaped and is preferably provided with friction-enhancing means to keep the device in place. The system is particularly useful for systemic administration of drugs and hormones. | 01-28-2016 |
Wilhelmus Theodorus Antonius Maria De Laat, Breda NL
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20080261287 | Metabolic Engineering of Xylos Fermentation - The present invention relates to further genetic modifications in eukaryotic host cells that have been transformed to express a xylose isomerase that confers the host cell the ability of isomerising xylose to xylulose. The further genetic modifications are aimed at improving the efficiency of xylose metabolism and include e.g. reduction of unspecific aldose reductase activity, increased xylulose kinase activity and increased flux of the pentose phosphate pathway. The modified host cells of the invention are suitable for the production of a wide variety of fermentation products, including ethanol, in fermentation processes in which a source of xylose or a source of xylose and glucose are used as carbon source. | 10-23-2008 |
20100036174 | BUTANOL PRODUCTION IN A EUKARYOTIC CELL - The present invention relates to a transformed eukaryotic cell comprising one or more nucleotide sequence(s) encoding acetyl-CoA acetyltransferase, 3-hydroxybutyryl-CoA dehydrogenase, 3-hydroxybutyryl-CoA dehydratase, butyryl-CoA dehydrogenase, alcohol dehydrogenase or acetaldehyde dehydrogenase and/or NAD(P)H-dependent butanol dehydrogenase, whereby the nucleotide sequence(s) upon transformation of the cell confer(s) the cell the ability to produce butanol. The invention also relates to a process for the production of butanol. | 02-11-2010 |
20110143402 | DEGRADATION OF LIGNOCELLULOSIC MATERIAL - The present invention describes a method for the treatment of lignocellulosic material which method comprises contacting said lignocellulosic material with a composition comprising two or more enzyme activities, said enzyme activities being cellulase and/or hemicellulase activities, wherein the pH during the treatment is about 4.5 or lower, and the treatment is carried out at a dry matter content of 15% or more. | 06-16-2011 |
20120115186 | FERMENTATIVE PRODUCTION OF ETHANOL FROM GLUCOSE, GALACTOSE AND ARABINOSE EMPLOYING A RECOMBINANT YEAST STRAIN - The present invention relates to a process for the production of one or more fermentation product from a sugar composition, comprising the following steps: | 05-10-2012 |
20120225451 | METABOLIC ENGINEERING OF XYLOSE-FERMENTING EUKARYOTIC CELLS - The present invention relates to genetic modifications in eukaryotic host cells that have been transformed to express a xylose isomerase that confers on the host cell the ability to isomerize xylose to xylulose. These genetic modifications are aimed at improving the efficiency of xylose metabolism and include. e.g., reduction of nonspecific aldose reductase activity, increased xylulose kinase activity and increased flux of the pentose phosphate pathway. The modified host cells of the invention are suitable for the production of a wide variety of fermentation products, including ethanol, in fermentation processes in which a source of xylose or a source of xylose and glucose are used as carbon source. | 09-06-2012 |
Wilhelmus Theodorus Antonius Marie De Laat, Breda NL
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20140342396 | FERMENTATIVE PRODUCTION OF LIPIDS ON AN INDUSTRIAL SCALE USING CHEMICALLY DEFINED MEDIA - We describe the use of chemically defined media for the fermentative production of valuable compounds on an industrial scale. Microbial strains which are suitable for fermentation on an industrial scale using a chemically defined medium include fungal, yeast and bacterial strains. Suitable strains can be obtained as wild type strains or by screening and selection after mutagenic treatment or DNA transformation. | 11-20-2014 |
Wouter De Laat, Rotterdam NL
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20100062947 | CIRCULAR CHROMOSOME CONFORMATION CAPTURE (4C) - The present invention relates in one aspect to a method for analysing the frequency of interaction of a target nucleotide sequence with one or more nucleotide sequences of interest (eg. one or more genomic loci) comprising the steps of: (a) providing a sample of cross-linked DNA; (b) digesting the cross-linked DNA with a primary restriction enzyme; (c) ligating the cross-linked nucleotide sequences; (d) reversing the cross linking; (e) optionally digesting the nucleotide sequences with a secondary restriction enzyme; (f) optionally ligating one or more DNA sequences of known nucleotide composition to the available secondary restriction enzyme digestion site(s) that flank the one or more nucleotide sequences of interest; (g) amplifying the one or more nucleotide sequences of interest using at least two oligonucleotide primers, wherein each primer hybridises to the DNA sequences that flank the nucleotide sequences of interest; (h) hybridising the amplified sequence(s) to an array; and (i) determining the frequency of interaction between the DNA sequences. | 03-11-2010 |
Wouter Leonard De Laat, Utrecht NL
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20130183672 | 3-D GENOMIC REGION OF INTEREST SEQUENCING STRATEGIES - The invention relates to methods for determining the sequence of a genomic region of interest comprising a target nucleotide sequence comprising, fragmenting a crosslinked DNA, ligating the fragmented cross linked DNA, reversing the crosslinking and determining at least part of the sequences of ligated DNA fragments which comprise a target nucleotide sequence. | 07-18-2013 |